• 정보처리학회논문지B
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• 제13B권5호
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• pp.515-524
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• 2006

배경추출은 비디오 감시 시스템에서 움직이는 물체를 찾는데 중요한 기술이다. 본 논문에서는 벡터 정렬을 이용한 새로운 온라인 컬러 배경 추출 방법을 제안한다. 제안된 방법에서 배경은 물체보다 발생빈도가 높다는 사실을 이용하여, 연속된 프레임의 컬러화소 값들의 벡터 미디언을 그 화소에서의 배경이라 간주한다. 본 알고리즘에서 현재 프레임의 물체는 얻어진 배경과의 거리가 문턱치보다 큰 화소들의 집합으로 구성된다. 알고리즘의 성능을 평가하기 위하여 온라인 가우시안 혼합 모델(Gaussian Mixture Model)을 이용한 다중 배경추출 방법과 비교하였으며, 비교결과 유사 또는 우월한 실험 결과를 확인하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권14호
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• pp.5913-5916
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• 2015

Gestational trophoblastic neoplasia (GTN) is the malignant form of gestational trophoblastic disease. In non-metastatic GTN, the outcomes of treatment are impressive with methotrexate (MTX) or actinomycin D. We retrospectively reviewed the outcomes of non-metastatic GTN treated at our center from January, 1999 to December, 2013. One hundred and nine patients were recruited to the study. The median age was 33.1 years and over 90% were referral cases. Abnormal vaginal symptoms developed in 37.6% while 56.4% were asymptomatic. The most common antecedent pregnancy was a complete mole (92.7%) with the median interval time from antecedent pregnancy to GTN development being 2.0 months. The median pretreatment B-hCG was 5,624 mIu/ml. The most common first line treatment was methotrexate (MTX) and folinic acid (91.7%) followed by weekly MTX (4.6%), etoposide+ MTX+actinomycin D (EMA) (2.8%), and actinomycin D (0.9%), with the median number of cycles at 5.0. The positive response to first line chemotherapy was 73.8%. The patients were given subsequent chemotherapeutic regimens after resistance to the first line therapy and showed a final remission rate of 89.9%.The significant factor that was frequently found in patients who were non-responders to the first line treatment was a hysterectomy procedure. Two patients developed lung metastasis and brain metastasis at one and four years after the first treatment, respectively. In conclusion, the outcomes of non-metastatic GTN were excellent. However, the patients need long term follow up due to the possibility of developing multiple organ metastases.

• 대한전자공학회논문지SP
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• 제38권4호
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• pp.77-77
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• 2001

MMMF(Modified 2D Multi-shell Median Filter)를 기초로 하여 가변 문턱 조건과 홀/짝수 다중셀을 이용한 Adaptive Odd/Even MMF(Multi-shell Median Filter)를 제안하였다. 제안된 알고리즘은 MATLAB을 이용하여 연구하고 테스트하였다. 제안된 알고리즘의 성능은 이미 잘 알려진 이미지에 임펄스 노이즈(Impulse Noise)와 Line Missing을 적용하여 평가하였고 이를 FPGA로 구현하였다. 제안된 가변 문턱 조건은 연산 시간과 불필요한 재배치를 줄였고, 홀수 셀과 짝수 셀은 각각 십자 방향과 대각선 방향의 Line Missing을 복구하였다. 특히 짧은 연산 시간으로 실시간을 요구하는 이미지 처리 분야에서 효과적으로 이용할 수 있다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권6호
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• pp.2483-2487
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• 2015

This study was conducted to evaluate the effectiveness of a combination of gemcitabine and nedaplatin therapy among patients with metastatic urothelial carcinoma previously treated with two lines of chemotherapy. Between February 2009 and August 2013, 30 patients were treated with gemcitabine and paclitaxel as a second-line chemotherapy. All had received a first-line chemotherapy consisting of methotrexate, vinblastine, doxorubicin and cisplatin. Ten patients who had measurable histologically proven advanced or metastatic urothelial carcinoma of the urinary bladder and upper urinary tract received gemcitabine $1,000mg/m^2$ on days 1, 8 and 15 and nedaplatin $70mg/m^2$ on day 2 as a third-line chemotherapy. Tumors were assessed by imaging every two cycles. The median number of treatment cycles was 3.5. One patient had partial response and three had stable disease. The disease-control rate was 40%, the median overall survival was 8.8 months and the median progression-free survival was 5.0 months. The median overall survival times for the first-line and second-line therapies were 29.1 and 13.9 months, respectively. Among disease-controlled patients (n=4), median overall survival was 14.2 months. Myelosuppression was the most common toxicity. There were no therapy-related deaths. Gemcitabine and nedaplatin chemotherapy is a favorable third-line chemotherapeutic option for patients with metastatic urothelial carcinoma. Given the safety and benefit profile seen in this study, further prospective trials are warranted given the implications of our results with regard to strategic chemotherapy for patients with advanced or metastatic urothelial carcinoma.

• Asian Pacific Journal of Cancer Prevention
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• 제13권8호
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• pp.4153-4156
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• 2012

Purpose: To investigate the efficacy and toxicity of a combination of gemcitabine with nedaplatin (GN) or cisplatin (GC) for patients with unresectable or recurrent esophagus squamous cell carcinoma. Methods: Gemcitabine was administered at 1 g/m2 intravenously on days 1 and 8; and nedaplatin or cisplatin were administered at 80 mg/m2 intravenously on day 1. We analyzed the response rate, overall survival time, progression-free survival time, and toxicity in 21 patients treated with GN and 27 patients treated with GC. Results: In patients treated with gemcitabine plus nedaplatin, the ORR was 47.6%, the median progression-free survival time was 4.1 months, and the median survival time was 9.3 months. In patients treated with gemcitabine plus cisplatin, the ORR was 48.2%, the median progression-free survival time was 3.9 months, and the median survival time was 9.1 months, respectively. There were no statistically significant differences in ORR, PFS and OS between the two groups. In both, the most commonly observed toxicities were thrombocytopenia and fatigue. Nausea and vomiting was more frequent in the GC group than in the GN group. Conclusion: Gemcitabine based chemotherapy was effective and tolerable for patients with unresectable or recurrent esophagus squamous cell carcinoma refractory to first line chemotherapy.

• 한국인터넷방송통신학회논문지
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• 제11권6호
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• pp.87-91
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• 2011

본 논문에서는 하나의 필드만을 사용하여 비월 주사 영상을 순차 주사 영상으로 변환하는 디인터레이싱 방법을 제안한다. 먼저, ELA 기법을 이용하여 에지의 방향성을 예측한다. 에지의 방향성을 정확히 예측하였을 경우에는 ELA(Edge-based Line Average) 기법에 의한 화소를 보간하고 에지의 방향을 잘못 예측하였을 경우에는 다시 새로운 에지의 방향을 결정한다. 결정된 방향에 대하여 화소를 본 논문에서 제안한 중간값 필터(median filter)를 이용하여 보간한다. 모의실험 결과 기존의 비인터레이싱 방법에 비해 주관적 및 객관적 화질이 개선됨을 보인다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권6호
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• pp.2771-2774
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• 2012

Aim: Tumors of upper gastrointestinal tract are among the cancers that have a quite lethal course. Cytotoxic chemotherapy is the most efficient therapeutic modality for metastatic gastric cancer. In patients who do not respond to first-line treatment, the response rate to second-line therapies is generally low and the toxicity rates high. This study concerned the efficacy and the side effect profile of second-line therapy with irinotecan in the patients who were being followed-up with the diagnosis of metastatic gastric cancer in $\dot{I}$zmir, Turkey. Materials and Methods: We retrospectively evaluated the efficacy and toxicity in 31 patients with metastatic gastric adenocarcinoma who presented to the polyclinic of Medical Oncology of Izmir Ataturk Education and Research Hospital between May 2008 and July 2011. All received chemotherapy regimens containing cisplatin, fluoropyrimidine (5-FU) and docetaxel as the first-line therapy for late stage disease. Irinotecan as a single agent was given at a dose of 210 mg/$m^2$ on each 21 days. Irinotecan (180 mg/$m^2$ on day 1), 5-FU (500 mg/$m^2$ on days 1-2) and leucovorin (LV; 60 mg/$m^2$ on days 1-2) as a combined regimen were given over a 14 day period. Results: Median age was 54 (range, 31-70). Irinotecan was given as a combined regimen for median 6 cycles (range, 3-12) and as a single agent for median 3 cycles (range, 1-10). Metastases were detected in one site in six patients (19%), in two different sites in 17 patients (55%) and in three or more sites in eight patients (26%). Four patients (12.9%) showed partial response and six patients (19.3%) showed stable disease. Progression-free survival (PFS) was found to be 3.26 months (95% CI, 2.3-4.2). Median overall survival (OS) was found to be 8.76 months (95% CI, 4.5-12.9). The most commonly seen grade 3/4 side effect was neutropenia but the the therapy was generally well-tolerated. Conclusions: In this study, it was demonstrated that second-line therapy with irinotecan given following the first-line therapy with cisplatin, fluoropyrimidine (5-FU) and docetaxel was efficient and safe. Further studies are needed for confirmation.

• 한국ITS학회 논문지
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• 제3권2호
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• pp.75-83
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• 2004

2004. 7. 1. 서울시는 대중교통 체계 개편의 하나로 강남대로, 성산-수색로, 도봉-미아로에 중앙버스전용차로제를 확대 시행하고 있다. 1996년부터 천호대로에서 실시한 중앙버스전용차로의 속도가 평균 35km/h를 나타내고 있는 것을 보면 버스의 속도 향상은 분명한 것으로 판단된다. 중앙버스전용차로를 시행하면 교차로상의 좌회전이 문제가 된다. 버스가 기존 1차로를 진행하기에 좌회전 차량들은 2차로에서 좌회전 할 수밖에 없다 원래 중앙버스전용차로를 실시하면 교차로의 좌회전은 허용치 않아야 한다. 하지만 좌회전을 허용치 않을 경우 지역 주민들의 반발과 다른 우회로 확보의 어려움 등의 문제가 제기된다. 이에 본 연구에서는 중앙버스전용차로를 시행하면서 기존의 교차로 좌회전은 허용한다는 전제하에 교차로 좌회전을 보다 안전하게 할 수 있는 방안으로 교차로 정지선을 분리하고, 그 적정 거리 산출 방안을 제시하고자 한다.

• Journal of information and communication convergence engineering
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• 제10권1호
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• pp.1-4
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• 2012

Given separated points divided by a line, called a wall, in a plane, we aim to make a gate in the wall to connect the separated points to each other. In this setting, the problem is to find a location for the gate that minimizes the average distance between the points. The problem is a variant of the well-known facility location problem, which is extensively studied in the fields of operations research, location theory, theoretical computer science, and so on. In this paper, we consider the $L^1$-distance of the points in the plane. The points are projected onto the wall and so the problem is transformed to a proximity problem of points on a line. Then it is shown that the transformed problem is related to the weighted median problem of points on the line. Therefore, we obtain an O(n log n)-time algorithm to solve our problem.

• 대한치과의사협회지
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• 제13권5호
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• pp.457-461
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• 1975

The author observed the relationships beween the dental midline and the midsagittal plane by taking 242 cases P-A cephalo-graphy grouped by male and female 2-6 years age group, 7-15 years age group, and adult age group. The following results were obtained by the observation. 1. Generally, the median line almost coincided with dental midline ineach age group. 1. It showed som degree of deviation in each age group. 2. It showed some degree of deviation in each age group. 3. The some degree of deviation shifted in accordance with each age group. 4. In adult age group, the dental milline more coincided with median line in male than in female.