• Herbal Formula Science
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• v.13 no.2
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• pp.1-16
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• 2005

Objectives: To find out the effects GGTl, an antiobestic drug widely used in clinics, has on the blood-antiobestic index and the toxicity index using the data from the hGHTg obese male rats. We looked closely into both of the two indices because GGTl antiobestic effect can happen not only by pharmacological action, but also by its toxicity. Also, we verified the difference in effect between GGTl and reductil (sibutramine), which has been approved by the FDA of the United States. Methods: After performing the experiments for 8 weeks on the hGHTg obese male rats divided into three groups: the control group, the GGTl group, and the reductil (RD) group, we anesthetized the rats with Diethyl ether and took a 3ml blood sample from the heart. Then, after coagulating the blood in room temperature by using the plasma separator, we centrifuged it for 25 minutes in 3,000rpm using the high-speed refrigerated centrifuge. We kept the separated plasma in a deep freezer at $-80^{\circ}C$, and repeatedly measured the antiobestic index and the toxicity index twice using the hematology biochemistry analyzer. Also, in order to judge the indirect toxicity index, we separated liver from kidney and observed them. Results: When we looked at the results of the analysis of covariance on the measuring elements related to the antiobestic index (TC, HDL, LDL, TG, and GLU), there was no significant difference among the groups in all measuring elements. Also, the results of the analysis of covariance on the two roups (RD group and GGTl group) showed that the p-values had no significant difference under the level of significance 0.05. When we looked at the result of the analysis of covariance on the measuring elements related to the toxicity index (GOT, GPT, GGT, CREA, UA, ALB, and TP), we could see that the p-values in GPT, ALB, and TP have a significant difference among the groups. Also, the results of the analysis of covariance about the measuring elements related to the toxicity index on both groups, RD group and GGTl group, showed no significant difference in the p-values of all of the measuring elements in the two groups, RD and GGTl group. Conclusions: In conclusion, through this experiment, the safety of GGTl has been approved, and although the verification on its medical effect has not been clearly approved, when we consider the fact that it belongs to the same group as reductil, an antiobestic drug approved by the FDA of the United States, we could indirectly verify that GGTl has an antiobestic effect. We believe that when doing a sample design for a future experiment, it needs to be performed on a greater sample size based on the power analysis that needs to be performed primarily in experiments, and a more accurate verification is needed through more systematic experiment plans.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.33 no.2
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• pp.128-136
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• 2011

Purpose: Errors in orthognathic model surgery occur during the planning, measuring and/or moving of the models. However, there has been little effort to find ways to reduce these errors. In this study, we introduce a new orthognathic model surgery technique (Yonsei method) which adopts the tooth point as the reference and the occlusal index as a moving vehicle for the model. Methods: The technique consists mainly of: 1) measuring the three-dimensional lengths of model points, 2) fabricating and moving the occlusal index and 3) verifying the movement. Then we compared the accuracy of the Yonsei method to conventional methods, with special reference made to influencing factors. Results: Errors for the Yonsei method with the occlusal index were reduced to the range of 0.61~1.04 mm in three-dimension, providing a more accurate model surgery technique than conventional methods which have errors ranging from 0.77~3.11 mm. Conclusion: It provided us a more accurate model surgery technique based on the reference points onto the teeth and the use of occlusal index.

• Health Policy and Management
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• v.5 no.1
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• pp.132-160
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• 1995

This study purported to acquire information necessary to improve the management of general hospitals. It tried to determine major indices which represent managerial performance of general hospitals and to identify the managerial characteristics of general hospitals which affect the major financial indices. Eighty-eight hospitals were chosen from 188 hospitals which were subject to standardization audit by the Korean Hospital Association. The results of a discriminant analysis are summarized as followings. First, when a single index was used to measure managerial performance of the sample hospitals, the ration of net profit to total capital was the best index and its discriminant power was 58.14%. The ratio of the number of boardmen((M. D.) and average daily medical cost were highly related to this index. Second, when two indices were used, income growth rte and the ration of net profit to total capital had the highest discriminant distinction ability. Their discriminant power was 61.9%. In this case, the ratio of the number of boardmen(M. D.) was significantly and highly related to the indices. Third, when all three indices-income growth rate, the ration of net profit to total capital and quick ratio - were used together, a discriminant function was statistically insignificant. Therefore, using all three indices was not useful in measuring managerial performance of the sample hospitals. In conclusion, using two indices-income growth rate and the ration of net profit to total capital-was better in measuring manegerial performance of general hospitals than using a single index. The independent variable which affected these indices was the ration of the number of boardmen. The discriminant function was : $D_{GI}=2.77+4.832\times(the ratio of the number of boardmen)$ *G=growth index(income growth rate) *I=profit index(the ration of net profit to total capital)

• Journal of Korean Society for Quality Management
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• v.24 no.4
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• pp.90-102
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• 1996

Process incapability index which is intended to evaluate the process capability by measuring process incapability provides more detailed information by dividing information about the process mean and variance. But when the target value is not consistent with the center of specification, it is very difficult to evaluate the process capability accurately. Thus it is necessary to improve the existing process incapability index. The improved process incapability index can identify the variation of the process faster than other process capability indices when applied firstly, to the precision process which can be affected sensitively by the change of the process, secondly, to the ordinary process where cost difference from the change of process is noticeable. By using subindices such as inaccuracy index and imprecision index, it is easier for quality manager to find where the cause of the variation of process is, and to take necessary action in advance.

• Journal of the korean academy of Pediatric Dentistry
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• v.25 no.1
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• pp.157-161
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• 1998

The teeth and gingivae of 20 children with asthma aged up to 6 years who had been taking syrup medicines regularly for at least six months were compared with those of a control group of 79 children of similar ages. Dental disease was assessed by measuring dental plaque(plaque index) and gingivitis(gingival index). The results of this study show that long-term administration of syrup medicine ketotifen sweetened with glucose increase the plaque index and gingival index in children who had primary dentition. But there was no significant difference between the two groups. By increasing the intake duration of syrup, both indices were increased.

• Journal of Biomedical Engineering Research
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• v.33 no.1
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• pp.8-14
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• 2012

The purpose of this study was to evaluate how much effect to accuracy when measuring abdominal fat by Computed Tomography (CT) under different respiration movements. The study volunteer composed of 66 normal adults ($50.4{\pm}11.2$ years, 33 males, 33 females). We measured their obesity by using Broca index, body mass index (BMI) and CT and have investigated the correlation. The CT scanning for the obesity measurement have done in two ways, one was done in stopping breath after exhaling and the other was holding a breath after inhaling. The results showed no statistically significant difference among the three measuring techniques. And, the error in two ways of inhaling and exhaling was showed 24.2% of volunteers. The two ways of respiration movements made different result in visceral fat area (P = 0.044), subcutaneous fat area (P = 0.636) and abdominal obesity value (P = 0.012). This study demonstrates that the two ways of respiration movements when scanning CT makes change in accuracy in visceral fat area, and in abdominal obesity quantitative measure. Therefore, our study suggests that CT should take twice in two ways while a patient stops breath after exhaling and holds a breath after inhaling when measuring abdominal obesity using CT equipments.

• Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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• 2002.10b
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• pp.91-92
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• 2002

Most studies of elsatohydrodynamic lubrication are oriented only to the measurement of film thickness itself with optical interferometer. In order to exactly investigate the characteristics of a certain lubricant under the condition of additives. especially for traction performance. it is also important to get the information of traction force as well. In this work. we developed the device for measuring friction force of EHL contact condition, which can trace the film thickness over the contact area with optical interferometer. To verify the validity of the measuring system, the friction force and film thickness under EHL condition are measured with the variation of additive ratios of viscosity Index improvers.

• Journal of the Korean Magnetics Society
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• v.6 no.1
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• pp.36-39
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• 1996

We have constructed a disp1acerrent sensor for measuring dynamic magnetostriction of an arrvrphous ribbon under alternating magnetic field using fiber optic Fabry-Perot interferorreter. The signal of the sensor was depen¬dent on the index matching oil and the optical isolator. The resolution of the sensor was $30{\AA}$ and the measured peak to peak magnetostriction of the amorphous ribbon $Fe_{81}B_{13.5}Si_{3.5}C_{2}$ was $28{\times}10^{-6}$.

• Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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• 2002.05a
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• pp.267-271
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• 2002

Most studies of elsatohydrodynamic lubrication are oriented only to the measurement of film thickness itself with optical interferometer. In order to exactly investigate the characteristics of a certain lubricant, it is also important to get the information of traction force as well. In this work, we developed the device for measuring friction force of ehl contact condition together with the film thickness. To verify the validity of the measuring system, the friction force and film thickness under ehl condition are measured with the variation of additive ratios of viscosity index Improvers.

• Journal of the Korean Society of Marine Environment & Safety
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• v.4 no.2
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• pp.43-52
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• 1998

Generally, the navigational safety of a ship under various loading conditions is evaluated by a loading manual. However, the loading manual handles only statical factors such as weight and buoyancy of ship without including any wave conditions. Practically ship's safety is much concerned with the occurrences on the rough sea as propeller racing, rolling, deck wetness, vertical acceleration, lateral acceleration, slamming and so on. The purpose of this paper is to present a synthetic and practical evaluation method of navigational safety using the integrated seakeeping performance index(ISPI) under loading conditions of ship in seaways. The method is calculated by means of the ISPI by measuring only vertical acceleration. Judgement of dangerousness is carried out for four lading conditions : homogeneous full loaded, half loaded, heavy ballast loaded, and normal ballast loaded conditions. In developing the practical evaluation system of navigational safety, it is useful to solve the difficulties in measuring factors by sensors. And by applying the evaluation diagrames, navigators are able to avoid dangerousness by keeping away of the danger encountering angle of wave direction which the diagram shows.