• Food Science and Biotechnology
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• 제16권6호
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• pp.1060-1063
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• 2007

The antioxidative activity of Alpinia oxyphylla was investigated through measuring the radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) and inhibitory activity for linoleic acid peroxidation. Two antioxidative diarylheptanoids, yakuchinone A (1) and oxyphyllacinol (2), were isolated from the fruits of A. oxyphylla using thin layer chromatography (TLC) autographic assays. The DPPH scavenging activities of the compounds ($IC_{50}=1$, $57{\pm}2.1\;{\mu}M$; 2, $89{\pm}3.1\;{\mu}M$) were lower than vitamin C ($IC_{50}=51{\pm}1.1\;{\mu}M$), but higher than butylated hydroxytoluene (BHT, $IC_{50}=99{\pm}2.2\;{\mu}M$). Also, inhibitory activities for linoleic acid peroxidation of the compounds ($IC_{50}=1$, $0.19{\pm}0.011\;mM$; 2, $0.31{\pm}0.009\;mM$) were higher than those of vitamin C ($IC_{50}=0.59{\pm}0.017\;mM$) and BHT ($IC_{50}=0.52{\pm}0.014\;mM$). In addition the $^{13}C-NMR$ data of oxyphyllacinol (2) have been first reported in this paper.

• 대한통합의학회지
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• 제5권2호
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• pp.43-50
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• 2017

Purpose : There is no validated method for measuring the toe flexor strength that can isolate the intrinsic muscles of the foot from the extrinsic muscles. This study compared the hallux flexion force (HFF) and muscle activity in the foot and ankle according to ankle position [plantarflexion (PF), neutral, and dorsiflexion (DF)]. Method : The study enrolled 17 subjects. In the sitting position, the HFF and activities of the abductor hallucis (AbdH), tibialis anterior (TA), and gastrocnemius (GCM) muscles were measured using a digital dynamometer and a wireless electromyography system, respectively. Subjects were instructed to flex the great toe maximally in three different ankle positions. Three 5-second trials were performed to measure the HFF and muscle activities in each condition. Repeated-measures ANOVA was used to compare the variables and paired t-tests with the Bonferroni correction were used for post-hoc pair-wise comparisons. The significance level was set at .016. Result : The HFF in DF was significantly greater than in any other ankle position (p<.01). The TA activity was greatest in ankle DF and that of the GCM was greatest in PF (both p<.01). However, there was no significant difference in AbdH activity according to ankle position. Conclusion : These results suggest that selective strength measurement of the foot intrinsic muscles in HFF should be performed with the ankle in the neutral position.

• 생명과학회지
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• 제20권6호
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• pp.960-963
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• 2010

왕겨를 증류하여 생성된 왕겨초 증류액을 이용하여 접촉성 피부염에 어떤 영향이 있는지를 검토하였다. 왕겨초 증류액(2%)에 자소옆을 첨가한 샘플은 dinitrochlorobenzene에 의해 유발된 접촉성 피부염 질환 동물모델에서 피부상피조직의 비후정도를 약 20%정도의 수준으로 완화시키며, 이는 면역조직화학적인 방법으로 확인하였다. 이 결과로, 왕겨초 증류액은 아토피 완화 효과를 가지므로 이들의 적합한 조건을 확립한다면 향장소재 또는 이의 조성물로 유용하게 이용될 수 있다고 판단된다.

• Journal of Plant Biology
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• 제7권3호
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• pp.9-14
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• 1964

The sensitivities of Chlorella ellipsoidea to ${\gamma}$-ray from Cobalt-60 were determined by measuring the photosynthetic and respiratory activities and the changes in phosphate contents in various fractions of the irradited cells, which were further grown in a standard medium after irradiation, were compared to those of non-irradiated normal cells. The photosynthetic and repiratory activities of the cells were almost inversely proportional to the dose of ${\gamma}$-ray irradiated and the photosynthetic activity was more sensitive than the respiratory activity of the cells. The most sensitive to ${\gamma}$-ray was growth activity, followed by photosynthesis, exogenous and endogenous respirations of the cells in decreasing order. Chlorella cells were so resistant to ${\gamma}$-ray comapred with other organisms that about 280,000 r dose of ${\gamma}$-ray irradiaton was necessary to reduce as much as half the subsequent photosynthetic activity. When the irradiated algae were further cultured in a standard medium, the phosphate contents in the fraction of DNA, RNA and phosphoprotein decreased considerably compared with those of non-irradiated normal cells, while the phosphate contents in the fraction of polyphosphates increased than those of control. Therefore, it was deduced that ${\gamma}$-ray inhibited the synthesis of DNA from polyphosphates, that the growth of Chlorella cells were consequently retarded.

• PNF and Movement
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• 제8권1호
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• pp.11-19
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• 2010

Purpose : The purpose of this study was to the effect of task-oriented arm movements and muscle enhancement program using elastic bands on limb muscle strength and activities of daily living of mitochondrial myopathy patient. Method : Single-subject experimental research design was applied to. AB Design was adopted. The study period was approximately four weeks. A baseline period of the three sessions of the experiment, the treatment period B, 3 sessions were conducted. Baseline period to observe the patient's daily life bardel index was measured as an independent feature, MMT as a limb muscle strength was assessed by measuring early. During the period of treatment with serabaendeu limb strength training 30 minutes after the break five minutes after the treatment using MMT limb muscle strength were evaluated. Task-oriented exercise program, and who exercise a week as a treatment was carried out in 30 minutes. Result : All of the scores for each sessional period of treatment when compared to base line and upper limb muscle strengthening exercises on the subjects that did not change significantly. Conclusion : If the muscles and nervous system involvement in patients with symptoms such as muscle weakness and paralysis of upper extremity functional use is difficult.

• Bulletin of the Korean Chemical Society
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• 제24권12호
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• pp.1785-1792
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• 2003

Zirconia modified with $MoO_3$ was prepared by impregnation of powdered $Zr(OH)_4$ with ammonium heptamolybdate aqueous solution followed by calcining in air at high temperature. Spectroscopic studies on prepared catalysts were performed by using FTIR, Raman, XRD, and DSC and by measuring surface area. Upon the addition of molybdenum oxide to zirconia up to 15 wt%, the specific surface area increased in proportion to the molybdate oxide content, while acidity measured by irreversible chemisorption of ammonia exhibited a maximum value at 3 wt% of $MoO_3$. Since the $ZrO_2$ stabilizes the molybdenum oxide species, for the samples equal to or less than 30 wt%, molybdenum oxide was well dispersed on the surface of zirconia and no phase of crystalline $MoO_3$ was observed at any calcination temperature above $400^{\circ}C$. The catalytic activities for cumene dealkylation were roughly correlated with the acidity of catalysts measured by ammonia chemisorption method, while the catalytic activities for 2-propanol dehydration were not correlated with the acidity because weak acid sites are necessary for the reaction.

• 한방재활의학과학회지
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• 제26권3호
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• pp.51-58
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• 2016

Objectives This study was designed to investigate whether the Cheongajihwang-Tang (CT) has an inhibitory effect association with oxidation or inflammation in RAW264.7 cells. Methods Cytotoxic activity of CT extract on RAW264.7 cells was evaluated by using 3-[4, 5-dimethylthiazol-2-yl]-2, 5-diphenyltetrazolium bromide (MTT) solution. Nitric oxide production was measured using Griess reagent system. The total phenolic contents and 1,1-Diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity was measured to evaluate the anti-oxidative effects of CT. Dichlorofluorescin diacetate (DCFH-DA) has been used as a substrate for measuring intracellular oxidant production. Results Cheongajihwang-Tang does not impair the cell viability in tested concentration. CT showed anti-oxidative effects in vitro by decreasing electron donating ability, and also showed anti-inflammatory effects suppressing NO and ROS expression in LPS induced RAW264.7 activation. CT inhibited the generation of intracellular ROS production as dose dependant manner. Conclusions CT has anti-oxidative effects and anti-inflammatory activities. These results indicate that CT extract has an anti-inflammatory activities via anti-oxidative effects.

• 한국식품영양과학회지
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• 제30권6호
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• pp.1301-1304
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• 2001

본 연구는 사과의 구취억제인자를 구명하기 위한 기초자료로써 사과 추출물의 획분에 따른 사과에서 추출한 PPO의 methyl mercaptan에 대한 구취 억제활성을 조사하였다. 사과를 탁즙하여 구취 억 제 활성 을 측정 해 본 결과, 사과 고형 분의 농도가 증가함에 따라 구취억제활성이 증가하는 경향을 나타내었다. 사과의 저분자획분에 PPO를 첨가한 경우, 저분자 획분의 농도증가 및 반응시간에 따른 methyl mercaptan에 대한 구취억제활성이 증가하는 경향을 나타내었다. 이상의 결과는 사과에서 추출한 PP7에 의한 갈변반응의 중간체로 생성되는 o-quinone이 methy mercaptan과 결합하여 meth- yl mercaptan을 비 휘 발성으로 전환시켜 구취억제활성을 나타내는 것으로 생각된다

• 대한인간공학회지
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• 제29권6호
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• pp.915-924
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• 2010

Muscular strength in the elderly is important factors deciding on functional state in daily lives, and functional state shows a health condition. Resistance training to prevent loss of muscle mass and muscle fiber atrophy due to aging can increase muscle mass and strength. Recently, resistance training to improve muscular strength and endurance has been actively researched. Resistance training increases activities of daily living and ability of the elderly, which makes healthy senescent. ADL/IADL is suitable for measuring health condition of the elderly. In this study, target muscles of resistance training were chosen through a correlation analysis between ADLs and elementary motion, and we presented a procedure to select target muscles and exercise equipments. This procedure consist of a survey method that were described detailed motion of ADL/IADL. So we should be to extract resistance training machine to improve functions of regarding fundamental motion. Result of study may improve daily life activities of the elderly through objectives and scientific approaches. Furthermore, it will be helpful to studies about various fields of the elderly.

• BMB Reports
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• 제37권4호
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• pp.416-421
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• 2004

The antioxidant activities of NADH and of its analogue, 1,4-dihydro-2,6-dimethyl-3,5-dicarbethoxy-pyridine ($PyH_2$), were evaluated in vitro. NADH was found to be oxidized by the peroxyl radical derived from 2,2-azobis-(2-amidinopropane) dihydrochloride (AAPH) decomposition, in a pH-dependent manner. Both NADH and $PyH_2$ inhibited the peroxidation of egg yolk lecithin (EYL) liposomes, although $PyH_2$ was more effective than NADH when 2,2'-azobis-4-methoxy-2,4-dimethyl-valeronitrile (methoxy-AMVN) was employed to induce EYL liposome peroxidation. The antioxidant activities of NADH and $PyH_2$ were also evaluated by measuring their influences on 1,3-diphenylisobenzofuran (DPBF) fluorescence decay in the presence of peroxyl radicals. NADH and $PyH_2$ were much more effective at inhibiting DPBF quenching in Triton X-100 micelles than in liposomes. These results indicate that NADH can inhibit lipid peroxidation despite being hydrophilic. Nevertheless, membrane penetration is an important factor and limits its antioxidant activity.