• Nuclear Medicine and Molecular Imaging
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• v.41 no.2
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• pp.91-96
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• 2007

The measurement of pathologically low levels of tissue $pO_2$ is an important diagnostic goal for determining the prognosis of many clinically important diseases including cardiovascular insufficiency, stroke and cancer. The target tissues nowaday have mostly been tumors or the myocardium, with less attention centered on the brain. Radiolabelled nitroimidazole or derivatives may be useful in identifying the hypoxic cells in cerebrovascular disease or traumatic brain injury, and hypoxic-ischemic encephalopathy. In acute stroke, the target of therapy is the severely hypoxic but salvageable tissue. $^{18}F-MISO$ PET and $^{99}mTc-EC-metronidazole$ SPECT in patients with acute ischemic stroke identified hypoxic tissues and ischemic penumbra, and predicted its outcome. A study using $^{123}I-IAZA$ in patient with closed head injury detected the hypoxic tissues after head injury. Up till now these radiopharmaceuticals have drawbacks due to its relatively low concentration with hypoxic tissues associated with/without low blood-brain barrier permeability and the necessity to wait a long time to achieve acceptable target to background ratios for imaging in acute ischemic stroke. It is needed to develop new hypoxic marker exhibiting more rapid localization in the hypoxic region in the brain. And then, the hypoxic brain imaging with imidazoles or non-imidazoles may be very useful in detecting the hypoxic tissues, determining therapeutic strategies and developing therapeutic drugs in several neurological disease, especially, in acute ischemic stroke.

• Journal of Korea Soil Environment Society
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• v.3 no.1
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• pp.83-92
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• 1998

This study presents a relationship between gas quantity and measurement resistance using the bubble meter, the water head indicator and the rotor meter from the gas vent sanitary landfill. From the one-dimensional analyses and experiments, the below results have been obtained. The gas volume sourcing from the gas vent depends on the permeability of final cover soil, its cover depth and distance between the gas vents. The total gas volume producing in the interested domain may be accurately measured by the bubble meter, the water head indicator and the rotor meter if the clay is used for the final cover soil. The required times approaching to the steady-state are different with respect to the flow meters, one day is for the bubble meter and the water head indicator and one hour for the rotor meter.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.32 no.2
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• pp.87-92
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• 2019

In this paper, we have verified a low-voltage EM(elasto-magnetic) sensing technique for tensile force management of PSC(prestressed concrete) internal tendon in order to apply the technique to actual construction sites where stable power supply is difficult. From observation of past domestic and overseas PSC structural accident cases, it was found that PS tension is very important to maintain structural stability. In this paper, we have tried to measure the tensile force from a magnetic hysteresis curve through EM sensors according to voltage value by using relation between magnetostriction and stress of ferromagnetic material based on elastic-magnetic theory. For this purpose, EM sensor of double cylindrical coil type was fabricated and tensile force test equipment for PS tendon using hydraulic tensioning device was constructed. The experiment was conducted to confirm relationship between changes of permeability and tensile force from the measurement results of the maximum / minimum voltage amount. The change of magnetic hysteresis curve with magnitude of tensile force was also measured by reducing amount of voltage step by step. As a result, the slope of estimation equation in accordance with magnitude of magnetic field decreases with the voltage reduction. But it was confirmed a similar pattern of change of magnetic permeability for the magnetic hysteresis loop. So, in this study, it is considered that it is possible to manage the tensions of PSC internal tendon using EM sensing technique in low-voltage state.

• Korean Journal of Metals and Materials
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• v.48 no.6
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• pp.523-532
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• 2010

Co-application of organic coating and cathodic protection has not provided enough durability to low-alloyed steels inseawater ballast tank (SBT) environments. An attempt has made to study the effect of alloy elements (Al, Cr, Cu, Mo, Ni, Si, W) on general and localized corrosion resistance of steels as basic research to develop new low-allowed steels resistive to corrosion in SBT environments. For this study, we measured the corrosion rate by the weigh loss method after periodic immersion in synthetic seawater at $60^{\circ}C$, evaluated the localized corrosion resistance by an immersion test in concentrated chloride solution with the critical pH depending on the alloy element (Fe, Cr, Al, Ni), determined the permeability of chloride ion across the rust layer by measuring the membrane potential, and finally, we analyzed the rust layer by EPMA mapping and compared the result with the E-pH diagram calculated in the study. The immersion test of up to 55 days in the synthetic seawater showed that chromium, aluminium, and nickel are beneficial but the other elements are detrimental to corrosion resistance. Among the beneficial elements, chromium and aluminium effectively decreased the corrosion rate of the steels during the initial immersion, while nickel effectively decreased the corrosion rate in a longer than 30-day immersion. The low corrosion rate of Cr- or Al-alloyed steel in the initial period was due to the formation of $Cr_2FeO_4$ or $Al_2FeO_4$, respectively -the predicted oxide in the E-pH diagram- which is known as a more protective oxide than $Fe_3O_4$. The increased corrosion rate of Cr-alloyed steels with alonger than 30-day exposure was due to low localized corrosion resistance, which is explained bythe effect of the alloying element on a critical pH. In the meantime, the low corrosion rate of Ni-alloyed steel with a longer than 30-day exposure wasdue to an Ni enriched layer containing $Fe_2NiO_4$, the predicted oxide in the E-pH diagram. Finally, the measurement of the membrane potential depending on the alloying element showed that a lower permeability of chloride ion does not always result in higher corrosion resistance in seawater.

• Korean Chemical Engineering Research
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• v.49 no.6
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• pp.786-789
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• 2011

In order to estimate the possibility of applying electrolytes generally used in solid oxide fuel cells(SOFCs) to direct carbon fuel cells(DCFCs), properties of YSZ(yttria stabilized zirconia) electrolyte were evaluated. In this study, vacuum slurry coating method was adapted to coat thin layer on anode support substrate. After sintering the electrolyte at $1400^{\circ}C$ for 5hrs, microstructure was analyzed by using SEM image. Also, gas permeability and ionic conductivity were measured to find out the potential possibility of electrolyte for DCFCs. The YSZ electrolyte represented dense coating layer and low gas permeability value. The ionic conductivity of YSZ electrolyte was high over $800^{\circ}C$. After measurement of the electrolyte properties, direct carbon fuel cell was fabricated and its performance was measured at $800^{\circ}C$.

• The Korean Journal of Nuclear Medicine
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• v.28 no.3
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• pp.338-342
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• 1994

Pulmonary clearance of Tc-99m-DTPA(PCD) has been used for the measurement of polmonary epithelial permeability. It has been reported to be increased not only in variety of polmonary diseases including ARDS, interstitial fibrosis, and smokers, but also in normal subjects on positive end expiratory pressure respirator, or after exercise. It was also noted that decrease of pulmonary blood flow due to pulmonary arterial obstruction results in delayed PCD. Normal range of PCD varies with institutes. We prospectively measured PCD in 17 normals (5 males and 12 females) consisted of staffs and trainees in the department of radiology of Kangnam St. Mary's hospital using original Bark Nebulizer (India). Age ranged from 32 to 43 years. 370 MBq of Tc-99m-DTPA was inhaled in supine position and supine posterior images were subsequently obtained with 1 min/frame, $64{\times}64$ matrix and word mode for 30min. Regions of interest were set on each lung, whole lungs, and upper, middle and lower thirds of right lung, respectively. Best fit regression curve was obtained by least square method from initial 7min after peak activity on each curve and time for half clearance of maximum activity (t1/2) was calculated. Mean t1/2 was $51{\pm}11.2min$ for whole lung. There was no significant difference between t1/ 2 of right and left lungs. Initial uptake was higher in the lower third and t1/2 was shorter in the lower third than in the upper third(P<0.05). We reviewed several reports on PCD and compared our data with the others. In this study, faster clearance in the lower third may be due to the position imaged with or the environment the subjects belong to, and further investigation is under way.

• Journal of the Korean Electrochemical Society
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• v.11 no.4
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• pp.256-261
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• 2008

In this study, Nafion membrane was modified to prevent methanol crossover by layer-by-layer self assembly using polyaniline (PANi) as a polycation and sulfonated poly(ether sulfone) (SPES) as a polyanion onto the Nafion surface. Since PANi and SPES possess thermal and chemical stability and rigid backbone, their layer-by-layer self-assembled films on the Nafion are expected to reduce methanol permeability and to increase mechanical stability. UV-Vis absorption spectroscopy verified a linear build-up of the multilayers of PANi and SPES. We found that the thickness per bilayer was about 10 nm by TEM measurement. Although modified Nafion membrane exhibited 15% decrease of proton conductivity, it reduceded 67% of methanol permeability compared to that of the pristine Nafion membrane, resulting in 2.5 times larger selectivity. At the performance test of the fuel cell using 5M methanol as a fuel, the modified Nafion membrane showed 2.4 times higher maximum power density at $30^{\circ}C$ and 1.4 times larger at $60^{\circ}C$ than the pristine Nafion.

• Journal of the Korean Magnetics Society
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• v.3 no.2
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• pp.130-134
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• 1993

The magnetic properties of the amorphous $Fe_{73.5-X}Co_{X}Cu_{1}Nb_{3}Si_{13.5}B_{9}(x=2,\;4)$ alloys, fabricated by a single roll rapid quenching technique and annealed at $400~650^{\circ}C$, have been investigated. The optimum annealing temperature is $550^{\circ}C$ for the amorphous $Fe_{71.5}Co_{2}Cu_{1}Nb_{3}Si_{13.5}B_{9}$ alloy. The properties of the nanocrystalline $Fe_{71.5}Co_{2}Cu_{1}Nb_{3}Si_{13.5}B_{9}$ alloy show the relative permeability of $1.1{\times}10^{4}$ and the coercive force of 0.22 Oe at 1 kHz. When annealed at $600^{\circ}C$, the nanocrystalline $Fe_{69.5}Co_{4}Cu_{1}Nb_{3}Si_{13.5)B_{9}$ alloy shows the relative permeability of $1.0{\times}10^{4}$ and the coercive force of 0.19 Oe at 1 kHz. From the X-ray measurement, it is found that the remarkably improved soft magnetic properties are the effect of the formation of $\alpha$-Fe(Si) grain. By the results of FMR exper-imeIlt, the optimum annealing condition is just below temperature which the peak-to-peak line width of FMR spectrum increase rapidly.

• Journal of the Korean Institute of Gas
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• v.27 no.3
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• pp.98-107
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• 2023

This study presents a well spacing design for coalbed methane(CBM) reservoirs using the experimental results of methane gas adsorption measurement of coal samples obtained from North Kalimantan Island, Indonesia. The gas productivity analysis shows that the cumulative gas production increases as the Langmuir volume increases. This indicates that the maximum gas adsorption directly affects the gas production. In addition, the maximum gas production increases with the increase of reservoir permeability, and the dewatering period is shortened. In particular, the cumulative gas production increases as the production influence area increases. However, when comparing productivity per unit well, the maximum cumulative gas production is found between 2,000 ft of depth and 80-160 acres of the influence area. When reservoir depth and production influence area are considered simultaneously, the results of the appropriate well depth and spacing calculations show that gas productivity is highest between 600-2,000 ft. In this case, it is appropriate to design well spacing in the range of 80-160 acres. Therefore, well spacing design considering coalbed depth in undeveloped CBM reservoirs can be accomplished using gas sorption test results from coal samples.

• Journal of the Korean Geotechnical Society
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• v.28 no.11
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• pp.41-52
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• 2012

Suction drain method can directly apply vacuum pressure to the soft ground through vertical drains so it can make hardening zones around them. These hardening zones make steeply lower the discharge efficiency of the pore water with decreasing permeability. This paper considered a stepped vacuum pressure to minimize a hardening zone which is one of the important parameters that can decrease discharge efficiency. A series of laboratory tests were conducted in order to examine the effect of the hardening zones and to evaluate their effects to the ground improvements with varying durations which applied stepped vacuum pressures(-20kPa, -40kPa, -60kPa and -80kPa) with Busan marine clay. According to strength(CPT), water content test and theoretical investigation indicate a size of the hardening zone within 7cm and the decreasing ratio of permeability about 2.0~4.0. Also, the total settlements are larger for the stepped vacuum pressure than the instant vacuum loading. The application time with vacuum pressure is determined considering the geotechnical properties of the interested clays. Results of numerical analysis show that consolidation behavior is appropriate to measurement for considering hardening zones.