• 한국의료질향상학회지
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• 제5권2호
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• pp.258-276
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• 1998

This study was conducted to justify the "prescribed shelf life" currently used in Samsung Medical Center and give recommendations based on scientific data to adopt for safe and cost-effective storage times for sterile goods Since the early 1970's, predetermined expiration dating policy has been used in Korea on all in-house sterilized products like any other countries; six months for the supplies wrapped in polyethylene peel pouches and two weeks for the rest. Recently, however, the studies suggest that current standards for preserving the sterility can be changing. It looks like we unnecessarily have too-short expiration date of sterilized supplies, that is far from being cost effective. Certainly, this research is an exciting project, especially in Korea, and will be leading and contributing to the paradigm shift of the conservative concept of shelf life for sterile supplies in Korean healthcare facilities. The major goal of this study was placed on the measurement of the recontamination time in packs wrapped in all kinds of wrapping materials used in S.M.C and stored in various conditions for periods ranging from three months to six months, and then develop a practical standard of "shelf life" based on the analyzed data. Objectives: To measure and compare the recontamination time of sterile packs among wrapppers and storage conditions, and develop a practical standard for the shelf life and storage conditions of sterile products. Samples and Method: The sterile integrity was investigated of the total 1,440 sterile sample packs containing gauze strip($1.5cm{\times}0.5cm$) we prepared and wrapped in nine wrapping materials (randomized reprocessed linens, linens reprocessed 99 times, linens reprocessed 120 times, new kraft paper, used kraft paper, new nonwoven fabrics, 6-time reprocessed nonwoven fabrics, new polyethylene peel pouches, used polyethylene peel pouches), and stored in four locations(closed cabinet of one of the typical wards, open shelf of one of ICUs, open shelf of separate storage room in ER, open shelf in OR), for three to six months, respectively in 1998. Each type of packs were opened weekly and the gauze strips inoculated into Brewer's thioglycollate broth at $35^{\circ}C$ for seven days. Results: There was no growth found for any types of the pack and storage conditions studied. Discussion: This study was conducted in an attempt to identify the possibility of extending the current shelf life for sterile goods we use in a sense of cost effectiveness. The findings suggest that we could extend our expiration dates, that means we can save a lot of materials and personnel time meeded for resterilizing, outdating, recleaning, wrapping, and reshelving. Then it will initiate a great reform in the field of healthcare in Korea, and now we are looking forward to this valuable revolution. We are going to continue this study and take all steps need to apply this new concept to our practice, and then trying to extend to other hospitals.

• 전자공학회논문지SC
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• 제49권2호
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• pp.55-62
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• 2012

정보기술과 의료기기의 융합에 의해 혈당을 집에서 측정하거나 운동 시에 심박수를 측정하는 것과 같이 건강관련 정보를 언제 어디서나 측정할 수 있게 되었고, 이에 따라 의료를 장소에 구애받지 않고 쉽게 접근할 수 있게 되었다. 최근에 유헬스케어 의료기기 시장이 빠르게 성장하고 있으나 이러한 기기의 안전성과 유효성을 평가하는 가이드라인이 아직 마련되지 않은 실정이다. 이를 위해 식약청, ISO/IEEE, CE 등 국내외의 유헬스케어 관련 규정을 조사하고, 이 중 유헬스케어 의료기기에 관련된 안정성 및 성능 평가에 대한 시험 방법과 항목을 제안하였다. 유헬스케어 의료기기의 가장 큰 특성인 무선 데이터 통신에 있어 데이터 무결성과 기기 사용환경이 다양하기 때문에 환경 요인이 기기에 미치는 영향을 평가하였다. 이를 바탕으로 휴대형 유헬스케어 의료기기의 평가 가이드라인을 제안하였다. 제안하는 지침을 기반으로 휴대형 유헬스케어 기기를 개발한다면 사용자들에게 보다 안전성과 신뢰도 높은 기기를 제공할 수 있을 것으로 기대된다.

• The Journal of Advanced Prosthodontics
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• 제3권3호
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• pp.161-165
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• 2011

PURPOSE. This randomized clinical trial was conducted to assess the safety and effectiveness of the ErhBMP-2 in alveolar bone regeneration as well as preservation of the ${\beta}$-TCP bone graft material that contains ErhBMP-2. MATERIALS AND METHODS. This study involved 72 patients at the 3 study centers. The patients, who were divided into 2 groups: the experiment group who had ErhBMP-2 coated TCP/HA and the control group who had TCP/HA graft material alone transplanted immediately after tooth extraction. CT was taken before and 3 months after the transplantation and healing status was compared between the two groups. The efficacy endpoints that were used to measure the degree of bone induction included alveolar bone height and 3 measurements of bone width. The paired t test was used to determine the significance of the changes (P<.05). RESULTS. Changes in alveolar bone height were $-1.087{\pm}1.413$ mm in the control group and $-.059{\pm}0.960$ mm in the experimental group (P<.01). At 25% extraction socket length [ESL], the changes were $0.006{\pm}1.149$ mm in the control group and $1.279{\pm}1.387$ mm in the experimental group. At 50% ESL, the changes were $0.542{\pm}1.157$ mm and $1.239{\pm}1.249$ mm, respectively (P<.01 for 25% ESL, and P<.05 for 50% ESL). During the experiment, no adverse reactions to the graft material were observed. CONCLUSION. ErhBMP-2 coated ${\beta}$-TCP/HA were found to be more effective in preserving alveolar bone than conventional ${\beta}$-TCP/HA alloplastic bone graft materials.

• 한국전산구조공학회논문집
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• 제30권6호
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• pp.501-506
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• 2017

적외선 유도 미사일은 미사일에서 자체적으로 방사하는 신호가 없어 항공기에서 접근을 인지하고 대응하기가 어렵다. 또한 적외선 유도 미사일을 탐지하는 MAW(missile approach warning)는 고가의 장비로 현재는 항공기에의 사용이 제한되고 있으며 그 효용성이 공개된바가 없다. 따라서 본 연구에서는 MAW가 탑재되어 항공기가 접근하는 유도 미사일에 대해 회피기동을 수행할 때 항공기의 생존성이 얼마나 증가하는지를 해석하여 MAW의 효용성을 평가하고자 하였다. 생존성의 평가지표로 위험 거리를 사용하였으며 고도 5km를 마하 0.9로 비행하는 항공기에 대해 AIM-9 적외선 유도 미사일이 접근하는 상황에 대한 위험 거리를 방위각 별로 도출하였다. 항공기의 회피기동에 대한 변수로는 5~7km의 MAW 인지거리와 3~7G의 항공기 기동성능을 고려하였다. 해석 결과 MAW를 통한 미사일 접근 인지와 회피기동 만으로도 위험 거리가 상당히 감소하는 것을 확인했다. 회피기동에 따른 위험 거리의 감소는 최대 29.4%로 나타났다. 또한 상대적으로 향상시키기 어려운 항공기 기동성능보다는 MAW 인지거리를 증가시키는 것이 위험 거리의 감소에 더 효과적인 것으로 나타났다.

• 정보교육학회논문지
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• 제23권5호
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• pp.469-480
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• 2019

새로운 2015 개정 교육과정이 추구하고 있는 목적 중의 하나는 4차 산업혁명 시대에 살아갈 학생들이 기본 학습 능력의 바탕 위에 다양한 발상과 도전으로 새로운 것을 창출하는 창의성을 기르는 것이다. 이에 따라 주어진 문제들을 합리적으로 해결하기 위하여 다양한 영역의 지식과 정보를 처리하고 활용할 수 있는 융합적 문제해결 역량이 중요시되고 있다. 이에 본 연구에서는 틴커캐드(Tinkercad) 모델링을 기반으로 하여 3D프린터를 활용한 융합교육을 설계하고 이를 수업에 적용하여 초등학생의 컴퓨팅 사고력 증진에 미치는 영향을 알아보았다. 연구 내용을 검증하기 위해 초등학교 6학년 25명 2개 반을 실험집단과 통제집단으로 나누고 실험집단에는 약 3개월간 3D프린터를 활용한 융합교육 프로그램 12차시를 적용하고, 통제집단에는 같은 시기 동안 동일 주제의 강의식 교과 수업을 진행하였다. 그 후에 컴퓨팅 사고력 검사 도구를 투입하여 사전-사후 검사로 t-검정을 실시하고 그 효과성을 알아보았다. 프로그램 적용 후 사후 검사에서 실험집단은 컴퓨팅 사고력이 통계적으로 유의하게 향상 되었으나, 통제집단은 통계적으로 유의한 차이가 없었다. 이 결과를 통해 틴커캐드 모델링 기반의 3D프린터를 활용한 융합교육이 초등학생의 컴퓨팅 사고력 증진에 긍정적인 영향을 미치는 것으로 보인다.

• Journal of Dental Anesthesia and Pain Medicine
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• 제23권1호
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• pp.19-28
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• 2023

Background: Fearful and anxious patients who find dental treatment intolerable without sedative and analgesic support may benefit from moderate sedation. Target controlled infusion (TCI) pumps are superior to bolus injection in maintaining low plasma and effect-site concentration variability, resulting in stable, steady-state drug concentrations. We evaluated the safety and efficacy of moderate sedation with remifentanil and propofol using TCI pumps in non-hospital dental settings. Methods: A prospective chart review was conducted on 101 patients sedated with propofol and remifentanil using TCI pumps. The charts were completed at two oral surgeons and one general dentist's office over 6 months. Hypoxia, hypotension, bradycardia, and over-sedation were considered adverse events and were collected using Tracking and Reporting Outcomes of Procedural Sedation (TROOPS). Furthermore, patient recovery time, sedation length, drug dose, and patient satisfaction questionnaires were used to measure sedation effectiveness. Results: Of the 101 reviewed sedation charts, 54 were of men, and 47 were of women. The mean age of the patients was 40.5 ±18.7 years, and their mean BMI was 25.6 ± 4.4. The patients did not experience hypoxia, bradycardia, and hypotension during the 4694 min of sedation. The average minimum Mean Arterial Pressure (MAP) and heartbeats were 75.1 mmHg and 60.4 bpm, respectively. 98% of patients agreed that the sedation technique met their needs in reducing their anxiety, and 99% agreed that they were satisfied with the sedation 24 hours later. The average sedation time was 46.9 ± 55.6 min, and the average recovery time was 12.4 ± 4.4 min. Remifentanil and propofol had mean initial effect-site concentration doses of 0.96 µ/.ml and 1.0 ng/ml respectively. The overall total amount of drug administered was significantly higher in longer sedation procedures compared to shorter ones, while the infusion rate decreased as the procedural stimulus decreased. Conclusion: According to the results of this study, no patients experienced adverse events during sedation, and all patients were kept at a moderate sedation level for a wide range of sedation times and differing procedures. The results showed that TCI pumps are safe and effective for administering propofol and remifentanil for moderate sedation in dentistry.

• 한국산학기술학회논문지
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• 제19권2호
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• pp.561-574
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• 2018

본 논문에서는 건강 불평등의 해소를 위하여 지리적 가중 회귀를 이용한 대사증후군 유병률의 지역별 변이 요인 및 관련 요인을 파악하고, 이를 통하여 지역의 효율적인 대사증후군 관리 사업 개발을 위한 적용방안을 마련하였다. 국민건강 보험공단 2015년 건강보험 통계연보 및 지역사회건강조사 등 기타 국가 기관 자료를 통하여 대사증후군 유병률과 사회경제적 수준의 사회구조적 요인, 그리고 물리적 환경, 건강행태, 이환, 정신건강, 예방관리, 의료이용의 중재 요인 지표를 수집하였다. 먼저 수집된 데이터를 바탕으로 대사증후군 유병률의 변이수준을 측정하는 지표인 EQ (Extremal Quotient)와 CV(Coefficient of Variations)를 이용하여 지역 간 변이가 존재함을 확인한 후, 공간적 이질성 및 의존성 등의 공간적 변이 고려가 가능한 지리적 가중 회귀(Geographically Weighted Regression)를 이용하여 대사증후군 유병률의 지역 간 변이 관련 요인을 분석하였다. 지리적 가중 회귀 분석 결과 대사증후군 유병률의 수준에 따라 주요 요인의 크기와 관리의 우선순위가 다름을 알 수 있었으며, 향후 지역별 대사증후군 관리의 목표와 우선순위 설정을 통한 관리 사업의 효과를 증대시킬 수 있는 방안마련이 가능함을 확인하였다.

• KDI Journal of Economic Policy
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• 제29권3호
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• pp.29-73
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• 2007

보육보조금은 일반적으로 여성의 노동시장참여를 용이하게 해주려는 것과 아동이 양질의 보육 및 교육 환경에서 돌보아지는 것을 돕는 목표로 지급된다. 본 연구는 보육시설을 이용하는 영아가구에 보육료를 지원하는 영아기본보조금의 효과를 살펴봄으로써 영아기본보조금이 그 정책목표를 달성하고 있는지 검토한다. 기본보조금이 2006년 민간보육시설에만 도입되었고 유아는 제외하고 영아에게만 지급된다는 준실험적(Quasi-Experiment) 설정을 이용하여 시설 측면과 가구 측면의 효과를 분석한다. 분석 결과, 보조금으로 인해 영아의 이용비중이 높은 보육시설에서는 교사의 처우 및 시설환경이 개선되는 등의 효과가 나타났으나 여성의 노동공급에는 거의 영향을 미치지 않았고, 수요자의 보육만족도에도 부정적 영향을 미친 것으로 나타났다.

• 동의생리병리학회지
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• 제34권2호
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• pp.102-116
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• 2020

The purpose of this study was to analyze the research trends of randomized controlled trials on herbal medicine treatment for atopic dermatitis in China for the last 5 years. We searched for randomized controlled trials with the intervention of herbal medicine for the treatment of atopic dermatitis in the CNKI (China National Knowledge Infrastructure) from January 2014 to December 2018. For the screening of the paper, we used '特应性皮炎' and '异位性皮炎' which mean atopic dermatitis and search was limited to three areas within Medicine & Public Health: Traditional Chinese Medicine, Traditional Chinese Medicinal Herbs, Combination of Traditional Chinese Medicine with Western Medicine. Among the 136 searched studies, we selected a total of 34 studies and analyzed a year of publication, subject characteristics, study design and intervention, prescribed herbal medicine and herbs, pattern identification, evaluation criteria, and outcomes. Longmu decoction (龍牡湯) and Polia Sclerotium (茯笭) was the most frequently prescribed medicine and herb. The most commonly used pattern identification was Blood deficiency and Wind-dryness (血虛風燥), and among them, the most frequently prescribed herb is Rehmanniae Radix (生地黃). In most studies using the total effectiveness and SCORAD index as an outcome measure, the herbal medicine treatment group showed statistically better results than the control group. As a result of the safety assessment, the herbal medicine treatment group was reported having significantly fewer side effects compared to the control group. Hence, it was confirmed that the intervention including herbal medicine had a significant effect on atopic dermatitis. This study would be able to provide the basis of clinical research on atopic dermatitis and applied to the treatment of atopic dermatitis.

• Asian Pacific Journal of Cancer Prevention
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• 제14권11호
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• pp.6451-6457
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• 2013

Background and Purpose: Indigenous people who leave their hometowns and move to the city to earn a living became urban aboriginals. During the process of adapting to urban living situations, they may use various coping strategies such as smoking to overcome their stress. Therefore, it is crucial to provide health education including smoking prevention, increasing knowledge regarding of tobacco hazard, self-efficacy of anti-smoking, and adjusting smoking behavior so as to empower their anti-smoking motivation to prevent lung cancer. The purpose of this study was to explore the effectiveness of an anti-smoking program on urban aboriginals in Taiwan. Methods: A quasi-experimental study design with purposeful sampling was employed. A total of 125 aboriginal subjects were recruited from two local churches at Shu Lin area in northern Taiwan. Subjects were divided into an experimental group (n =64 ) and a control group (n = 61). Both took pre-tests in order to set baseline values, and only the experimental group participated for 3-weeks in the anti-smoking program classes. Both groups took post-tests immediately after the intervention in order to evaluate the immediate effects of the teaching program, and a follow-up test was conducted four weeks after the intervention. Data were analyzed using descriptive statistics, one-way ANCOVA, and repeat measure ANCOVA. Results: After controlling for confounding variables, the results showed that there were statistically significant differences in the self-efficacy of anti-smoking and smoking behavior between experimental and control groups in the immediately post-test and the follow-up test (p < 0.05). However, there was no significant differences in the recognition of hazards of smoking at eiter time point. Conclusions and Implications for Practice: The findings of this study revealed that the anti-smoking program effectively improved self-efficacy of anti-smoking, and decreased the smoking behavior in urban aboriginals. They provide useful information as a reference regarding of aboriginal health promotion to health providers. It is imperative that anti-smoking be reinforced for those regular smokers to prevent induction of lung cancer.