• Journal of Preventive Medicine and Public Health
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• 제43권6호
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• pp.479-485
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• 2010

Objectives: The Korean Genome and Epidemiology Study (KoGES), a multicenter-based multi-cohort study, has collected information on body composition using two different bioelectrical impedence analysis (BIA) machines. The aim of the study was to evaluate the possibility of whether the test values measured from different BIA machines can be integrated through statistical adjustment algorithm under excellent inter-rater reliability. Methods: We selected two centers to measure inter-rater reliability of the two BIA machines. We set up the two machines side by side and measured subjects' body compositions between October and December 2007. Duplicated test values of 848 subjects were collected. Pearson and intra-class correlation coefficients for inter-rater reliability were estimated using results from the two machines. To detect the feasibility for data integration, we constructed statistical compensation models using linear regression models with residual analysis and R-square values. Results: All correlation coefficients indicated excellent reliability except mineral mass. However, models using only duplicated body composition values for data integration were not feasible due to relatively low $R^2$ values of 0.8 for mineral mass and target weight. To integrate body composition data, models adjusted for four empirical variables that were age, sex, weight and height were most ideal (all $R^2$ > 0.9). Conclusions: The test values measured with the two BIA machines in the KoGES have excellent reliability for the nine body composition values. Based on reliability, values can be integrated through algorithmic statistical adjustment using regression equations that includes age, sex, weight, and height.

• Journal of Chest Surgery
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• 제49권sup1호
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• pp.28-36
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• 2016

Background: This study aimed to develop the models for regional cardiac surgery centers, which take regional characteristics into consideration, as a policy measure that could alleviate the concentration of cardiac surgery in the metropolitan area and enhance the accessibility for patients who reside in the regions. Methods: To develop the models and set standards for the necessary personnel and facilities for the initial management plan, we held workshops, debates, and conference meetings with various experts. Results: After partitioning the plan into two parts (the operational autonomy and the functional comprehensiveness), three models were developed: the 'independent regional cardiac surgery center' model, the 'satellite cardiac surgery center within hospitals' model, and the 'extended cardiac surgery department within hospitals' model. Proposals on personnel and facility management for each of the models were also presented. A regional cardiac surgery center model that could be applied to each treatment area was proposed, which was developed based on the anticipated demand for cardiac surgery. The independent model or the satellite model was proposed for Chungcheong, Jeolla, North Gyeongsang, and South Gyeongsang area, where more than 500 cardiac surgeries are performed annually. The extended model was proposed as most effective for the Gangwon and Jeju area, where more than 200 cardiac surgeries are performed annually. Conclusion: The operation of regional cardiac surgery centers with high caliber professionals and quality resources such as optimal equipment and facility size, should enhance regional healthcare accessibility and the quality of cardiac surgery in South Korea.

• 여성건강간호학회지
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• 제8권4호
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• pp.506-520
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• 2002

The purpose of this study is to research the degree of recognition & performance of traditional postpartal care for postpartal women and to provide the basic data for improvement of service in a postpartum care center. The respondents of this study were 100 women of 6 postpartum care centers within a C province from Oct. 20 to Dec. 10, 2000. The instruments of measure were used for collecting data on the degree of recognition & performance of traditional postpartal care developed by the researcher. Data analysis consisted of frequency, percentage, mean, standard deviation, paired t-test, t-test, ANOVA which are calculated by Scheffe test and Cronbach's alpha which is used as a reliance level by using a SPSS-PC+. The results of the study were as follows:1. The average score for the degree of recognition of traditional postpartal care(Sanhujori) for postpartal women was $3.09{\pm}.31$, and they recognized that it was important. The methods which were ranked were as follows; Protecting the body from a harmful state, invigorating the body by the argumentation of heat and avoidance of cold, handling with whole heart, and keeping clean, resting without working, eating well. 2. The average score for the degree of performance of traditional postpartal care (Sanhujori) for postpartal women was $2.81{\pm}.31$, and they performed that it was important, too. The methods which were ranked were as follows; Protecting the body from a harmful state, invigorating the body by the augumentation of heat and avoidance of cold, eating well, handling with whole heart, and keeping clean, resting without working. 3. There were significant differences statistically (paired-t=-8.39, p=.000) of the degree of recognition & performance of traditional postpartal care(Sanhujori) for the postpartal women. The degree of recognition was higher than the degree of performance. So, the recognition of traditional postpartal care (Sanhujori) was higher than the performance of it. 4. There were no statistical differences of the degree of recognition & performance of traditional postpartal care(Sanhujori) among the postpartal women's age, religion, job, educational background, delivery frequency, delivery method or the sex of baby. So, the Characteristics of the respondents were not influenced as far as the degree of recognition & performance of traditional postpartal care(Sanhujori). 5. There were significant differences statistically of the degree of performance of traditional postpartal care(Sanhujori) among the 5 postpartum care centers except 1 postpartum care center(p<.01). So, the recognition of traditional postpartal care(Sanhujori) was higher than the performance of traditional postpartal care(Sanhujori) in the 5 postpartum care centers. But there was performed as good as recognition in only 1 postpartum care center.

• 농촌의학ㆍ지역보건
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• 제36권1호
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• pp.47-59
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• 2011

본 연구는 보건소 직원들이 인지하는 조직성격 유형과 조직시민행동의 실태를 직종 등의 특성별로 파악하여 특성 간 차이를 분석하기 위한 설문조사를 통한 서술적 조사연구이다. 조사대상은 22개 전라남도 보건소 중 12개 시 군 보건소에 근무하는 직원이며, 자료수집기간은 2009년 9월 15일-10월 14일로 1개월 간 실시되었으며, 자료분석 대상은 422명이었다. 조사대상 보건소의 조직성격유형은 외향형, 감각형, 사고형 및 판단지향형 조직에 속하며, ESTJ유형과 ISTJ유형으로 전형적인 공공조직으로서 구성원들이 인지하고 있었고, 조직성격유형 중에서 사고형은 성별(P=.007), 판단형은 연령(p=.010), 교육수준(p=.043) 및 근무경력(p=.000)에 따라 통계적으로 유의미한 차이가 있었으며, 직종별로는 통계적으로 유의한 차이가 없는 것으로 검증되었다. 조직시민 행동은 4.77점이었고, 예의성과 시민성이 높은 반면 스포츠정신이 낮은 것으로 나타났으나, 직종 간에 통계적으로 유의한 차이가 없었다. 따라서 보건소는 이타성, 시민성 및 예의성을 유지하는 가운데 스포츠 정신을 고양해야 할 것이다. 조직시민행동은 시민성, 양심성과 스포츠정신에서 연령과, 이타성은 교육 수준과, 그리고 경력과는 시민성, 양심성, 스포츠 정신 및 예의성과 유의한 차이가 나타났다. 결론적으로 보건소는 조직성격유형과 조직시민 행동에 대하여 직종보다는 연령, 성, 교육정도 및 경력 등 특성간의 차이가 있음을 고려하여, 이를 감안한 중재방안의 모색이 필요하다고 본다. 보건소 가 공공조직의 성격보다는 대민봉사활동에 적합한 조직성격으로의 모색에 있어서 조직시민행동의 증진을 위한 방안의 모색도 필요함을 제언한다.

• Journal of Microbiology and Biotechnology
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• 제29권4호
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• pp.651-657
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• 2019

Although smallpox was eradicated in 1980, it is still considered a potential agent of biowarfare and bioterrorism. Smallpox has the potential for high mortality rates along with a major public health impact, eventually causing public panic and social disruption. Passive administration of neutralizing monoclonal antibodies (mAbs) is an effective intervention for various adverse reactions caused by vaccination and the unpredictable nature of emerging and bioterrorist-related infections. Currently, vaccinia immune globulin (VIG) is manufactured from vaccinia vaccine-boosted plasma; however, this production method is not ideal because of its limited availability, low specific activity, and risk of contamination with blood-borne infectious agents. To overcome the limitations of VIG production from human plasma, we isolated two human single-chain variable fragments (scFvs), (SC34 and SC212), bound to vaccinia virus (VACV), from a scFv phage library constructed from the B cells of VACV vaccine-boosted volunteers. The scFvs were converted to human IgG1 (VC34 and VC212). These two anti-VACV mAbs were produced in Chinese Hamster Ovary (CHO) DG44 cells. The binding affinities of VC34 and VC212 were estimated by competition ELISA to $IC_{50}$ values of $2{\mu}g/ml$ (13.33 nM) and $22{\mu}g/ml$ (146.67 nM), respectively. Only the VC212 mAb was proven to neutralize the VACV, as evidenced by the plaque reduction neutralization test (PRNT) result with a $PRNT_{50}$ of ~0.16 mg/ml (${\sim}1.07{\mu}M$). This VC212 could serve as a valuable starting material for further development of VACV-neutralizing human immunoglobulin for a prophylactic measure against post-vaccination complications and for post-exposure treatment against smallpox.

• 대한간호학회지
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• 제32권2호
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• pp.219-230
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• 2002

This study was aimed at comparing and evaluating one main role, the professional self concept and job satisfaction of public health nurses and clinical nurses. Method: The data was collected from 72 nurses in 8 health centers and 86 nurses in 5 hospitals in Daegu city and Kyungpook province from May 5th to June 5th, 2001. This study was interviewed by trained social workers. The origin of questionnaires used in this study were PSCNI(Professional Self-Concept of Nurses Instrument) to measure the professional self concept of nurses and JDI(Job Descriptive Index) to measure the job satisfaction of nurses. The data was analyzed by SAS(version 6.12) and statistical methods used were Chi-square test, t-test, ANOVA(analysis of variables) and ANCOVA(analysis of covariate). Result: The findings of this study were as follows: 1. The most important domain in the main role of public health nurses were as counsellors, managers, mediators and evaluators. In clinical nurses, their main roles were, directors of nursing, researchers, spokesmans, and informers. 2. Public health nurses showed lower scores in the professional self concept of nurses than clinical nurses, what statistically significant tool was used to suggest this finding. 3. Public health nurses showed higher scores in job satisfaction than clinical nurses, but again, explain the tool used in these findings for give a rationals. 4. For public health nurses, general characteristics which affected professional self concept were age, educational level, and duration of job. In clinical nurses, the general characteristics which affected professional self concept were age, religion, marital status, and duration of job. 5. For public health nurses, there was no general characteristic which affected job satisfaction. In clinical nurses, the general characteristics which affected job satisfaction were age, religion, and duration of job. Conclusion: Nursing profession should give a training to competent nurses who can deliver high quality care to meet the needs of health consumers. The role of nurses has been expended and specialized as health conception has been changed in Korea.

• 한국운동역학회지
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• 제25권1호
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• pp.95-101
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• 2015

Objective : The purpose of this study was to analyze the effects of multisensory exercise on foot pressure sensitivity and balance for the elderly. Method : The subjects were 17 elderly women (11 for the experimental group and 6 for the control group) with a mean age of 83. The subjects all lived in senior residence centers in Seoul. Multisensory exercise was done twice a week for 40 minutes during a 12 week period. Exercise programs were changed every 3 weeks according to the principal of gradual progress of the exercise. In order to train the vision system subjects were asked to open and close their eyes during exercise. When it came to training the vestibular system, subjects stood and walked on high elastic mats with their bare feet. For the somatasensory system subjects always stood and walked with their bare feet. The sub-Metatarsal Pad Elasticity Acquisition Instrument (MPEAI) was used to measure foot pressure sensitivity. MFT Balance test (V1.7) was used to measure anterior / posterior and medial / lateral directional balance. For the statistical analysis the IBM SPSS 21.0 was used to perform Repeatde measured ANOVA and Wilcoxon ranked test. Results : For the multisensory exercise group Hallux (after 6 weeks, 12 weeks), heel (after 6 weeks) and 2nd Metartarsal $40^{\circ}$ (after 6 weeks) pressure sensitivity increased statistically, but the control group didn't change. Also, balance didn't change for the experimental and control group statistically. Conclusion : Exercise with bare feet on a high elastic mat had a partially positive effect on foot sensitivity.

• Journal of Preventive Medicine and Public Health
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• 제32권4호
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• pp.538-545
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• 1999

Objective : To compare the predictive power of International Classification of Diseases 10th Edition(ICD-10) based International Classification of Diseases based Injury Severity Score(ICISS) with Trauma and Injury Severity Score(TRISS) and International Classification of Diseases 9th Edition Clinical Modification(ICD-9CM) based ICISS in the injury severity measure. Methods : ICD-10 version of Survival Risk Ratios(SRRs) was derived from 47,750 trauma patients from 35 Emergency Centers for 1 year. The predictive power of TRISS, the ICD-9CM based ICISS and ICD-10 based ICISS were compared in a group of 367 severely injured patients admitted to two university hospitals. The predictive power was compared by using the measures of discrimination(disparity, sensitivity, specificity, misclassification rates, and ROC curve analysis) and calibration(Hosmer-Lemeshow goodness-of-fit statistics), all calculated by logistic regression procedure. Results : ICD-10 based ICISS showed a lower performance than TRISS and ICD-9CM based ICISS. When age and Revised Trauma Score(RTS) were incorporated into the survival probability model, however, ICD-10 based ICISS full model showed a similar predictive power compared with TRISS and ICD-9CM based ICISS full model. ICD-10 based ICISS had some disadvantages in predicting outcomes among patients with intracranial injuries. However, such weakness was largely compensated by incorporating age and RTS in the model. Conclusions : The ICISS methodology can be extended to ICD-10 horizon as a standard injury severity measure in the place of TRISS, especially when age and RTS were incorporated in the model. In patients with intracranial injuries, the predictive power of ICD-10 based ICISS was relatively low because of differences in the classifying system between ICD-10 and ICD-9CM.

• 해양환경안전학회지
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• 제11권2호
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• pp.27-32
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• 2005

본 연구는 해양사고 피해규모에 의해 우리나라 수색$\cdot$구조 구역의 위험수준을 평가하였다. 위험수준 평가를 위해서 전문가 지식에 기반한 퍼지로직, 퍼지측도 및 t-준노름 퍼지적분법을 이용하였다. 본 연구의 퍼지로직은 퍼지 확장원리에 의한 최대최소화 합성이고, 비퍼지화는 무게중심법을 이용하였고, 최종 평가는 t-준노름 퍼지적분법을 이용하였다. 그 결과 목포, 통영, 여수 수색$\cdot$구조 구역의 위험수준이 가장 높은 것으로 평가되어, 향후 위험수준을 경감하기 위해 많은 구조선과 구조장비가 필요 할 것으로 판단된다.

• Journal of Preventive Medicine and Public Health
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• 제16권1호
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• pp.5-11
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• 1983

1982년 5월 1일부터 9월 30일까지 5개월간 대구시내 중구 동구 서구 남구 북구 수성구 6개보건소에 등록되어 치료받고 있는 20세미만 폐결핵환자중 BCG접종 유무가 명확한 400명과 동 보건소에 참아온 일반환자 가운데 거주지역, 성 및 연령에 맞추어 뽑은 대조군 659명을 대상으로 BCG접종율을 기준삼아 BCG의 폐결핵 예방효과를 조사한 결과 그 성적을 요약하면 다음과 같다. BCG접종군이 비접종군보다 비교위험도가 2분의 1로 낮게 나타났으며, BCG접종으로 인한 예방효과는 51.5%였다. 따라서 BCG의 효과에 대한 많은 논란과 방해적으로 작용할요인, BCG접종으로 인한 합병증등 여러가지 문제들이 있으나 결핵유병율이 2.5%나되는 우리나라에서는 앞으로도 계속 BCG접종을 권장하여야 것 것으로 본다.