• Journal of Microbiology and Biotechnology
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• v.17 no.11
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• pp.1789-1796
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• 2007

A ${\beta}$-glucosidase with the molecular mass of 160,000 Da was purified to homogeneity from cell extract of a cellulolytic bacterium, Cellulomonas uda CS1-1. The kinetic parameters ($K_m$ and $V_{max}$) of the enzyme were determined with pNP-cellooligosccharides (DP 1-5) and cellobiose. The molecular orbital theoretical studies on the cellulolytic reactivity between the pNP-cellooligosaccharides as substrate (S) molecules and the purified ${\beta}$-glucosidase (E) were conducted by applying the frontier molecular orbital (FMO) interaction theory. The results of the FMO interaction between E and S molecules verified that the first stage of the reaction was induced by exocyclic cleavage, which occurred in an electrophilic reaction based on a strong charge-controlled reaction between the highest occupied molecular orbital (HOMO) energy of the S molecule and the lowest occupied molecular orbital (LUMO) energy of the hydronium ion ($H_3O^+$), more than endocyclic cleavage, whereas a nucleophilic substitution reaction was induced by an orbital-controlled reaction between the LUMO energy of the oxonium ion ($SH^+$) protonated to the S molecule and the HOMO energy of the $H_2O_2$ molecule. A hypothetic reaction route was proposed with the experimental results in which the enzymatic acid-catalyst hydrolysis reaction of E and S molecules would be progressed via $SN_1$ and $SN_2$ reactions. In addition, the quantitative structure-activity relationships (QSARs) between these kinetic parameters showed that $K_m$ has a significant correlation with hydrophobicity (logP), and specific activity has with dipole moment, respectively.

• Tunnel and Underground Space
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• v.9 no.2
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• pp.114-130
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• 1999

It is very important to study on the structural behaviors of structurally damaged tunnel linings. A series of centrifuge model tests were performed in order to investigate different behaviors of tunnel linings. A 1/100-scaled aluminum horseshoe tunnel linings with a radius 5 cm, height 8 cm were buried in a depth with dry Joomunjin standard sand, the relative density of which was 86%. Such sectional forces as bending moments and thrusts along the tunnel circumference were measured by twelve strain gages. Earth pressures in soil mass and on the outside of lining model were estimated by pressure transducers, ground surface settlements at a center and edges by using LVDTs.

• Journal of the Korean GEO-environmental Society
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• v.4 no.3
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• pp.79-88
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• 2003

This paper presents a numerical study of the spatial behavior of a linear absorbing solute in a heterogeneous porous medium. The spatially correlated log-normal hydraulic conductivity field is generated in a given two-dimensional domain by using the geostatistical method (Turning Bands algorithm). The velocity vector field is calculated by applying the two-dimensional saturated groundwater flow equation to the Galerkin finite element method. The simulation of solute transport is carried out by using the random walk particle tracking model with CD(constant displacement) scheme in which the time interval is automatically adjusted. In this study, the spatial behavior of a solute is analyzed by the longitudinal center-of-mass displacement, longitudinal spatial spread moment and longitudinal plume skewness.

• Coupled systems mechanics
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• v.7 no.4
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• pp.455-483
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• 2018

The study deals with physical modeling of a typical three storeyed building frame supported by a pile group of four piles ($2{\times}2$) embedded in cohesive soil mass using three dimensional finite element analysis. For the purpose of modeling, the elements such as beams, slabs and columns, of the superstructure frame; and that of the pile foundation such as pile and pile cap are descretized using twenty noded isoparametric continuum elements. The interface between the pile and the soil is idealized using sixteen node isoparametric surface element. The soil elements are modeled using eight nodes, nine nodes and twelve node continuum elements. The present study considers the linear elastic behaviour of the elements of superstructure and substructure (i.e., foundation). The soil is assumed to behave non-linear. The parametric study is carried out for studying the effect of soil- structure interaction on response of the frame on the premise of sub-structure approach. The frame is analyzed initially without considering the effect of the foundation (non-interaction analysis) and then, the pile foundation is evaluated independently to obtain the equivalent stiffness; and these values are used in the interaction analysis. The spacing between the piles in a group is varied to evaluate its effect on the interactive behaviour of frame in the context of two embedment depth ratios. The response of the frame included the horizontal displacement at the level of each storey, shear force in beams, axial force in columns along with the bending moments in beams and columns. The effect of the soil- structure interaction is observed to be significant for the configuration of the pile groups and in the context of non-linear behaviour of soil.

• Structural Engineering and Mechanics
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• v.27 no.6
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• pp.713-739
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• 2007

Nowadays computers can perform symbolic computations in addition to mere number crunching operations for which they were originally designed. Symbolic computation opens up exciting possibilities in Structural Mechanics and engineering. Classical areas have been increasingly neglected due to the advent of computers as well as general purpose finite element software. But now, classical analysis has reemerged as an attractive computer option due to the capabilities of symbolic computation. The repetitive cycles of simultaneous - equation sets required by the finite element technique can be eliminated by solving a single set in symbolic form, thus generating a truly closed-form solution. This consequently saves in data preparation, storage and execution time. The power of Symbolic computation is demonstrated by six examples by applying symbolic computation 1) to solve coupled shear wall 2) to generate beam element matrices 3) to find the natural frequency of a shear frame using transfer matrix method 4) to find the stresses of a plate subjected to in-plane loading using Levy's approach 5) to draw the influence surface for deflection of an isotropic plate simply supported on all sides 6) to get dynamic equilibrium equations from Lagrange equation. This paper also presents yet another computationally efficient and accurate numerical method which is based on the concept of derivative of a function expressed as a weighted linear sum of the function values at all the mesh points. Again this method is applied to solve the problems of 1) coupled shear wall 2) lateral buckling of thin-walled beams due to moment gradient 3) buckling of a column and 4) static and buckling analysis of circular plates of uniform or non-uniform thickness. The numerical results obtained are compared with those available in existing literature in order to verify their accuracy.

• Journal of the Society of Naval Architects of Korea
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• v.55 no.1
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• pp.56-65
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• 2018

Pressure oscillation caused by the compressibility of entrapped air in dam break flow is analyzed using an open source code, which is a two-phase compressible code for non-isothermal immiscible fluids. Since compressible flows are computed based on a pressure-based method, the code can handle the equation of state of barotropic fluid, which is virtually incompressible. The computed time variation of pressure is compared with other experimental and computational results. The present result shows good agreements with other results until the air is entrapped. As the entrapped air bubbles pulsate, pressure oscillations are predicted and the pressure oscillations damp out quickly. Although the compressibility parameter of water has been varied for a wide range, it has no effects on the computed results, because the present equation of state for water is so close to that of incompressible fluid. Grid independency test for computed time variation of pressure shows that all results predict similar period of pressure oscillation and quick damping out of the oscillation, even though the amplitude of pressure oscillation is sensitive to the velocity field at the moment of the entrapping. It is observed that as pressure inside the entrapped air changes quickly, the pressure field in the neighboring water adjusts instantly, because the sound of speed is much higher in water. It is confirmed that the period of pressure oscillation is dominated by the added mass of neighboring water. It is found that the temperature oscillation of the entrapped air is critical to the quick damping out of the oscillations, due to the fact that the time averaged temperature inside the entrapped air is higher than that of surrounding water, which is almost constant.

• Korean Journal of Applied Biomechanics
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• v.27 no.2
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• pp.133-140
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• 2017

Objective: The purpose of this study was to determine the relationship between center of pressure (CoP) and local stability of the lower joints, which was calculated based on approximate entropy (ApEn) during walking in elderly women. Method: Eighteen elderly women were recruited (age: $66.4{\pm}1.2yrs$; mass: $55.4{\pm}8.3kg$; height: $1.56{\pm}0.04m$) for this study. Before collecting data, reflective marker triads composed of 3 non-collinear spheres were attached to the lateral surface of the thigh and shank near the mid-segment to measure motion of the thigh and shank segments. To measure foot motion, reflective markers were placed on the shoe at the heel, head of the fifth metatarsal, and lateral malleolus, and were also placed on the right anterior-superior iliac spine, left anterior-superior iliac spine, and sacrum to observe pelvic motion. During treadmill walking, kinematic data were recorded using 6 infrared cameras (Oqus 300, Qualisys, Sweden) with a 100 Hz sampling frequency and kinetic data were collected from a treadmill (Instrumented Treadmill, Bertec, USA) for 20 strides. From kinematic data, 3D angles of the lower extremity's joint were calculated using Cardan technique and then ApEn were computed for their angles to evaluate local stability. Range of CoP was determined from the kinetic data. Pearson product-moment and Spearman rank correlation coefficient were applied to find relationship between CoP and ApEn. The level of significance was determined at p<.05. Results: There was a negative linear correlation between CoP and ApEn of hip joint adduction-abduction motion (p<.05), but ApEn of other joint motion did not affect the CoP. Conclusion: It was conjectured that ApEn, local stability index, for adduction/abduction of the hip joint during walking could be useful as a fall predictor.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.38 no.5
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• pp.575-584
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• 2014

In this study, the NREL 5 MW wind turbine tower model was optimized according to the multi-body dynamics and reliability-based design. The mathematical model was defined as a link-joint system including dynamic characteristics derived from Timoshenko's beam theory. For the optimization problem, the sensitivities to variations in the tower thicknesses and inner and outer diameters were acquired and arranged in terms of safety and efficiency according to bending stress and buckling standards. An optimal design was calculated with the advanced first-order second moment method and used to define a finite element model for validation. The finite element model was simulated by static analysis. The relationship between the multi-body dynamic and finite element method throughout the process was investigated, and the optimal model, which had high endurance despite its low mass, was determined.

• Journal of the Korea institute for structural maintenance and inspection
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• v.19 no.3
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• pp.48-54
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• 2015

In this study, we propose an innovative lateral force distribution building system between tall buildings by utilizing the difference of moment of inertia, resulting the reduction of lateral displacement and the lateral forces in terms of an alternative for the dense human and increased cost of lands in highly integrated city area. A successive collapse prevention means by providing additional bearing plate between connections is proposed. In addition to that, a more economical vibration reduction is expected due to the suggested tuned mass damper on the surface of spacial structure. In the considered verification examples, reduced drifts at the top location of the building systems are validated against static wind pressure loads and static earthquake loads. The suggested hybrid building system will improve the safety and reliability of the new or existing building system in terms of more than 30% reduced drift and vibration through the development of convergence of tall buildings and spatial structures.

• Korean Journal of Applied Biomechanics
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• v.17 no.1
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• pp.29-39
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• 2007

This study were obtained elapsed time phase-by-phases, displacement, user angle, velocity and angular velocity to analyse kinematically contributing factors at impact of forehand drive motion, on targeting three male players. The results of the study were presented as follows; In the forehand drive swing, the elapsed time by phases was a total of .52 seconds: .30 seconds from backswing to impact and .22 seconds from impact to follow-through, Considering the mean change in locations of COM of each(part$\rightarrow$body segment) at impact, racket head, left shoulder, right wrist and left hip, the left-right directions(X-axis) were showm to be each $.61{\pm}.03$, $1.19{\pm}.08$, $.66{\pm}.03$, $.94{\pm}.06$, and $.45{\pm}.03m$. The displacement differences of COM of each body segment were shown to be -.57, -.05, -.33, and .16m. For the vertical direction(Z-axis), the center of mass was lowest at impact and highest at E3. For the displacement of the right wrist on the left hip, the right wrist moved to .82m to the lower direction without change in the locations of the hip from E1 from E2. When the left hip moved .02m from E2 to E3, the right wrist moved .7m in the upper direction. In respect to the velocity of each body segment, the hip and the shoulder joint accelerated and then the wrist followed. Then the right wrists of all the subjects and their racket heads showed maximum speed, and an effective swing was observed. At the angle of each part, the angle of the right wrist was the smallest at the backswing and the largest at the moment of the impact. Then it increased gradually in the follow-through section. In respect of angular velocity for subject A, the hip moved and the largest change occurred. Immediately before the impact, the subject made a swing using his right wrist, his hip, and the shoulder joint, showing the maximum value, which was judged to be effective.