• Journal of Chest Surgery
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• 제20권3호
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• pp.548-551
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• 1987

Thoracoscopy, mediastinoscopy and/or mediastinotomy and explo-thoracotomy were performed and confirmed diagnosis of the 26 cases of the mediastinal tumors, those were admitted and treated at the Department of Thoracic and Cardiovascular surgery, Chonbuk National University Hospital, from June,1976 to September, 1986. We experienced 7 thoracoscopies, 7 mediastinoscopies &/or mediastinotomies, and 12 explo-thoracotomies. The most common histologic type was teratoma and lymphoma [6 cases]. Of the 26 cases of the histologically confirmed mediastinal tumor, 19 were benign tumors and 7 were malignants. 19 cases of benign tumors were surgically resected with good result but one case of the surgically resected malignant thymoma was recurred 4 months later. 6 cases of malignant lymphoma and one case of recurred malignant thymoma were treated with chemo-and radiation therapy. Thoracoscopy and mediastinoscopy with tissue biopsy were simple in procedure and had a tissue diagnosis with obtaining the pathologic tissue in a acceptable complication rate and reduced exploratory thoracotomy.

• Investigative Magnetic Resonance Imaging
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• 제25권4호
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• pp.338-344
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• 2021

Solitary fibrous tumors (SFT) are rare mesenchymal tumors that most commonly develop in the pleura; they rarely involve the diaphragm. MRI has not been widely used to evaluate SFTs of the thoracic cavity, though it may be highly useful in assessing local invasion, predicting malignant potential, and helping in the differential diagnosis. However, MRI findings of malignant SFTs of the diaphragmatic pleura have been described in only two cases. We report a rare case of a malignant solitary fibrous tumor of the diaphragmatic pleura in an 82-year-old man. We describe the clinical and characteristic imaging features, including computed tomography, conventional MRI, and diffusion-weighted imaging. Contrast-enhanced MRI is more accurate than is CT in identifying the origin of SFTs, predicting whether they ae benign or malignant, and assessing local invasion. This imaging modality proved helpful in deciding on the treatment strategy for these rare tumors.

• Journal of Chest Surgery
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• 제23권4호
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• pp.745-749
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• 1990

A wide variety of histologically or clinically different tumors and cysts can occur from the many anatomical structures located within the mediastinum. We report the analysis of the 26 cases of mediastinal tumors and cysts, experienced in the Department of Thoracic and Cardiovascular Surgery, College of Medicine, Hallym University from March 1983 to February 1990. Sex ratio of male to female was 1:1.16 and mean age was 33.4 years. Malignant tumors were 8 cases[30.7%], benign tumors were 18 cases[69.2%] The most common histologic types were thymoma, 6 cases[23%] and teratoma, 6 cases [23%] followed by neurogenic tumor, 4 cases[15%] and mediastinal tuberculoma, 3 cases [11.5%]. The most frequent symptoms were chest pain and discomfort. Most of benign tumors were completely removed and malignant tumors were treated with anticancer chemotherapy and radiotherapy after operation. Postoperative complications were developed in 4 cases[15.3%] and hospital mortality was 3.8%.

• Journal of Chest Surgery
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• 제16권4호
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• pp.594-601
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• 1983

Mediastinal tumors have long fascinated the thoracic surgeon because of their variety and unpredictability of diagnosis prior to exploration. We report the analysis of the 110 cases of mediastinal tumors, experienced in the dept. of the thoracic and cardiovascular surgery of the National Medical Center from December 1959 to August 1983. The age distribution was relatively even and the mean age was 37 years old. The germ cell tumors were 29 cases [31%], the neurogenic tumors were 19 cases [20%], the thymomas were 16 cases [17%], the lymphomas were 8 cases [8.5%], the primary or secondary carcinomas were 11 cases [12%], the bronchogenic and the P.W cysts were 4 cases, the mesenchymal tumors were 3 cases, the TB gangliomas were 3 cases among the 94 cases, histologically analysed. The malignant tumors were 39 cases [41%]. In classified by histological types, the tumor size, location and the clinical manifestations are presented. The successful removal was done in 53 cases [96%] among 55 cases of benign mediastinal tumors. In 39 malignant cases, the surgical intervention had been done in 21 cases [54%], and inoperable cases were 16 [41%], and the operative deaths were 2 cases [5%].

• Imaging Science in Dentistry
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• 제32권2호
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• pp.81-87
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• 2002

Purpose : To investigate the diagnostic significance of cortical changes in the bone of diseased jaws utilizing computed tomography (CT). Materials and Methods: Computed tomographic images of 91 patients, consisting of 7 osteomyelitis, 46 cysts, 18 benign tumors, and 20 malignant tumors, were analyzed. The pattern of cortical expansion was classified into three types: no expansion (N), buccal or lingual expansion (B/L), and buccolingual expansion (B & L). The pattern of cortical destruction was classified into four types: no destruction (N), point destruction (PO), gross destruction (GR), and permeative destruction (PE). The pattern of periosteal reaction was classified into four types: parallel, irregular, spicule, and Codmans triangle. The relationship between the pattern of cortical bone changes and diseases of the jaws was assessed. Results: When the pattern of cortical expansion was compared to diseases of the jaw, N-type was most prevalent in cases of osteomyelitis and malignant tumors, B/L-type with cysts, and B&L-types with benign tumors. Comparison between the pattern of cortical bone destruction with diseases of the jaw showed strong correlations between PO and PE-types to osteomyelitis, N-type with cysts, N and GR-types with benign tumors, and GR-type with malignant tumors. Finally, the relationship between the pattern of periosteal reaction to diseases of the jaw showed a strong correlation between parallel-type to osteomyelitis and spicule-type to malignant tumors. Conclusion : The pattern of cortical expansion and cortical destruction is useful in differentiating diseases of the jaws.

• Journal of Chest Surgery
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• 제30권3호
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• pp.353-353
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• 1997

흉막에 발생하는국소성 섬유성 종양은 드문 질환으로 대부분의 경우 단순흉부촬영상 우연히 발견되며 특징적 인 임상상 및 조직병 리학적 소견을 보인다. 본 논문에서는 증상없는 저혈당을 동반한 악성 국소성 섬유성 종양 1례 및 양성 국소성 섬유성 종양 2례를 보고하고자 한다. 악성의 예에서는 개흉술을 통해 종양을 절제해 내었고 수술직후 저혈당의 소실을 관찰할 수 있었으며 양성 2예에서는 비디고 흉강경을 이용하여 종양을 절제할 수 있었다.

• Journal of Chest Surgery
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• 제30권3호
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• pp.253.2-356
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• 1997

흉막에 발생하는국소성 섬유성 종양은 드문 질환으로 대부분의 경우 단순흉부촬영상 우연히 발견되며 특징적 인 임상상 및 조직병 리학적 소견을 보인다. 본 논문에서는 증상없는 저혈당을 동반한 악성 국소성 섬유성 종양 1례 및 양성 국소성 섬유성 종양 2례를 보고하고자 한다. 악성의 예에서는 개흉술을 통해 종양을 절제해 내었고 수술직후 저혈당의 소실을 관찰할 수 있었으며 양성 2예에서는 비디고 흉강경을 이용하여 종양을 절제할 수 있었다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권14호
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• pp.5899-5902
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• 2015

Background: To compare the current histologic distribution of lung cancer in Lebanon to the worldwide trends, according to the 2004 WHO Classification. Materials and Methods: 1,760 patients with a pulmonary pathology examination at Hotel-Dieu de France University Hospital between July 2009 and July 2014 were included. Results: Some 676 out of the total investigated patients (38.4%) had a lung tumor. In 665 (98.4%) the tumors were malignant, with a mean age at diagnosis of 63.8 years and a male/female (M/F) sex ratio of 1.7:1. Among the malignant tumors, 86.2% were epithelial tumors with a mean age at diagnosis of 64.8 years and an M/F sex ratio of 1.9. Other malignant tumors consisted of metastatic tumors (10.2%), lymphoproliferative tumors (2.1%) and mesenchymal tumors (1.5%). Most common carcinoma subtypes were adenocarcinoma (48.0%), squamous cell carcinoma (23.0%) and small cell carcinoma (13.3%). Carcinoid tumors were the only carcinoma subtype with an M/F sex ratio below 1 (0.7). Salivary gland tumors were the carcinoma with lowest mean age at diagnosis (45.5 years). Conclusions: The histologic distribution of lung tumors in Lebanon is similar to that in developed countries. We believe this resemblance is due to common smoking habits, known to be responsible for the increase of lung adenocarcinoma at the expense of other subtypes.

• Journal of Chest Surgery
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• 제31권10호
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• pp.988-994
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• 1998

연구배경 : 흉벽종양은 연부조직 종양과 골조직 종양으로 대별할 수 있으며 이를 다시 양성종양과 악성종양으로 구분할 수 있다. 재료 및 방법 : 한양대학병원 흉부외과 교실에서는 1973년 1월 부터 1997년 9월까지 치료한 원발성 흉벽종양 68례를 경험한 바, 이에 보고하는 바이다. 결과 : 환자는 총 68명으로 이중 남자가 33명 (48.5%), 여자가 35명(51.5%) 이었다. 환자의 연령은 10세에서 79세 사이로 평균연령은 39.4세이었다. 환자의 연령별 분포는 30대가 23명 (33.8%), 50대가 12명 (17.6%), 40대가 10명 (14.7%) 순이었다. 전체 종양중 양성종양이 53례이었고, 악성종양이 15례이었다. 양성종양은 30대에서 17례(32.1%), 악성종양은 30대에서 6례 (40%)로 나타나, 악성종양과 양성종양 모두 30대에서 가장 많았다. 양성종양중 섬유성 이형성증과 연골종이 각각 14례 (26.4%) 씩으로 가장 많았고, 골연골종과 지방종이 각각 8례 (15.1%) 씩이었다. 악성종양은 골육종이 8례(53.3%)로 가장 많았다. 종양의 발생부위는 골 및 연골조직이 49례, 연부조직이 19례이었다. 환자의 증상은 전례에서 종괴가 만져졌고 압통을 호소한 환자가 51례, 흉벽종양이 폐를 침범한 3례에서 호흡곤란을 호소하였다. 악성종양중 6례 (40%)에서 광범위 절제술을 하였고, 양성종양은 4례 (7.7%)에서 광범위 절제술을 하였다. 수술 후 인대양 종양 1례에서 재발을 하였다. 수술이나 수술 후 합병증으로 인한 사망자는 없었다. 결론 : 원발성 흉벽종양은 환자의 대부분에서 종괴가 만져져 내원하는 경우가 많았으며, 양성종양인 경우 절개로 치유되지만 악성종양인 경우 흉벽의 광범위 절개가 요구되고 이에 따른 흉벽 재건술이 필요할 수 있다.

• 대한골관절종양학회지
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• 제10권2호
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• pp.79-87
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• 2004

목적: 최근 자기공명영상의 개발로 다양한 연조직종양의 영상의학적 진단이 가능해 졌다. 그러나 연조직종양의 다양한 조직구성이나 시간에 따라 구성분의 변화는 자기공명영상 만으로 악성과 양성 종양조차 감별을 어렵게 한다. 이에 본 저자들은 임상과 자기공명영상의 복합적인 소견으로 악성과 양성 연조직종양을 감별해 보고자 하였다. 대상 및 방법: 병리조직학적으로 확진된 82례(중간성종양을 악성종양으로 포함하여 37례와 염증성 종괴를 양성종양으로 포함하여 45례)를 후향적으로, 임상적 소견으로 연령, 크기, 위치, 그리고 자기공명영상 소견으로 종양경계, T2신호강도양상, 조영제T1신호강도양상, 그리고 조영증강 범위를 연관시켜 분석하였다. 자기공명영상으로 진단이 어렵지 않는 많은 전형적인 지방종과 결절종 그리고 농양같은 낭종은 양성종양 분류에서 제외하였다. 결과: 악성연조직종양은 양성에 비하여 연령으로 21~40세와 61~80세, 크기로 3.0 cm 이상, 발생위치로 몸체-골반-하지, 그리고 자기공명영상에서 불규칙한 경계, 50%이상의 조영증강범위 소견들의 빈도가 높았다. 결론: 발생위치로 몸체-골반-하지 와 상지-어깨-척추 로 나눈 임상소견이 악성과 양성 연조직종양을 감별하는데 통계학적으로 유의성있는 차이를 보였으며 나머지 다른 소견들은 특이적이지는 않았지만 부가적으로 악성과 양성을 감별하는데 도움이 되는 소견이었다.