• Proceedings of the PSK Conference
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• 2002.10a
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• pp.309.2-309.2
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• 2002

The FimH subunit of type l-fimbriated Escherichia coli has been determined as a major cause of urinary tract infection. To produce a possible vaccine antigen against urinary tract infection, the fimH gene was genetically coupled to the ctxa2b gene, which was then cloned into pMAL -p2E expression vector. The chimaeric construction of pMALfimH/ctxa2b was transformed into Escherichia coli TB1 and its N-terminal amino acid sequence was analyzed. (omitted)

• Proceedings of the Korea Electromagnetic Engineering Society Conference
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• 2003.11a
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• pp.459-463
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• 2003

A circularly polarized microstrip patch antenna (MPA) using electromagnetic (EM) coupled fed method is analyzed in view of the two types of coupling mechanisms viz. cavity and parasitic type, proposed earlier. The patch-ground plane distance is varied in order to achieve the fore-mentioned types of couplings. For each case of patch-ground plane distance, the offset position of feedline is optimized for perfect matching and the boresight axial ratio (AR) is observed. It is seen that CP operation is possible only for cavity-type coupling (smaller patch-ground plane distances). The simulated results for the boresight AR for the two types of coupling mechanisms are presented.

• Microbiology and Biotechnology Letters
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• v.21 no.3
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• pp.229-238
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• 1993

An nlp (Ner like protein) gene from E. coli was previously cloned and sequenced. Here we show that expression of the sugar metabolism related genes, lacZ, malQ and malP, increased 2.5-to 8.3-fold in the presence of a plasmid containing the nlp gene. This suggested that the nlp gene could induce maltose- and lactose-metabolism coordinately with crp*1 in the absence of cAMP. Using the nlp-lacZ fusion gene, it was possible to show the promoter of nlp was active in vivo.

• Physical Therapy Korea
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• v.18 no.2
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• pp.67-75
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• 2011

The purpose of this study was to investigate the effects of virtual reality (VR) therapy with compensation inhibition and feedback (CIF) on upper extremity function in chronic stroke patients. Seven chronic stroke patients participated in this study, which was a randomized controlled trial with a crossover design. Self upper extremity exercise, conservative VR therapy, and VR therapy with CIF were performed for one hour per session, 5 times per week, over a 3 week period. The main outcome measures involved range of motion (ROM) including shoulder, elbow, and wrist joints, a Manual Function Test (MFT), and a Motor Activity Log (MAL). Data were calculated as posttest and pretest changes in every session and were analyzed using Friedman and Wilcoxon signed-rank tests at p<.05. The results were as follows: 1) Statistically significant increase in ROM measurements of shoulder and elbow joints were seen with VR therapy with CIF compared to VR therapy and self upper extremity exercise (p<.05), whereas no significant increasing was noted for the wrist joint (p>.05). 2) Statistically significant increase in the MFT was seen with VR therapy with CIF compared with VR therapy and self upper extremity exercise (p<.05). 3) VR therapy with CIF also resulted in statistically significant increase in both activity of use (AOU) (p<.05) and quality of movement (QOM) (p<.05) on the MAL test when compared with VR therapy and self upper extremity exercise, respectively. In conclusion, VR therapy with CIF was more effective than conservative VR therapy and self upper extremity exercise in improving the upper extremity function in hemiplegic patients with chronic stroke.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.7 no.2
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• pp.105-111
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• 2021

⁸⁹Zr is a positron-emitting radioisotope, which has known as well-suited radioisotope for use in a monoclonal antibody-based imaging agent for immuno-PET. The purpose of this study was to quantitatively evaluate the diagnostic ability of general trastuzumab and thio-trastuzumab as HER2 positive receptors based on Df hexadentate iron chelator. Desferrioxamine-p-SCN (Df-Bz-NCS) and desferroixamine-maleimide (Df-Mal) were purchased from Macrocyclics (Dallas, TX, USA). The trastuzumab was purchased from Roche (Schweiz), and thio-trastuzumab was obtained from professor Hyo-Jeong Hong group (Kangwon National University). The radioisotope ⁸⁹Zr was produced by domestic purification system and KIRAMS using medical cyclotron (50 MeV, Scantronix). The conjugates of Df-trastuzumab and Df-thio-trastuzumab were prepared with Df-Bz-NCS and Df-Mal under basic aqueous solution (pH 8-9) at room temperature, respectively. The conjugates purified by PD-10 column were mixed with dried ⁸⁹Zr chloride. ⁸⁹Zr-labeled conjugates were purified and concentrated by Amicon ultra centrifugal filter. The preparation step and time of ⁸⁹Zr-labeled conjugates was shorted as 4 steps within 2 hours. ⁸⁹Zr-labeled conjugates showed the highly radiochemical purity of over 98%, and were very stable until 7 days by the analysis of radio-ITLC method. Each radio-labeled conjugates were also exhibited the highly stability in both PBS buffer and mouse serum. Immuno-PET imaging of ⁸⁹Zr-labeled conjugates in mice bearing gastric cancer xenograft tumors with HER2 expression showed high tumor uptake in the NCI-N87 HER2-expressing. However, ⁸⁹Zr-Df-Mal-thio-trastuzumab showed a relatively lower tumor-to-background ratio than ⁸⁹Zr-Df-Bz-trastuzumab, as well as whole-body distribution. In the results, ⁸⁹Zr-Df-Bz-trastuzumab was evaluated to have a relatively higher HER2 diagnostic ability than ⁸⁹Zr-Df-Mal-thio-trastuzumab.

• Journal of Nutrition and Health
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• v.28 no.11
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• pp.1056-1064
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• 1995

This study was performed to investigate the difference between obese and non-obese male students. To conduct this study, anthropometric measurements, blood pressure, serum lipids and insulin concentration, and daily nutrients intake of obese and non-obese mal students were measured. The results are as follows : The anthrometric measurements of the two groups showed significant difference in weight (P<0.01), waist(P<0.001), hip(p<0.0001) and thigh (P<0.001) circumference, % of body fat(p<0.0001), kg of body fat(p<0.001) and LBM (lean body mass, p<0.0001). On the other hand, the blood pressure, serum lipids and insulin, and daily nutrients intake of the two groups showed no significant difference. The WHR showed positive correlation with weight, BMI, waist circumference, % of body fat and kg of body fat in obese group. It is also founded that waist circumference, % of body fat, kg of body fat, serum triglyceride, energy and carbohydrate intake in non-obese group showed positive correlation with WHR.

• The Journal of Korean Physical Therapy
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• v.23 no.5
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• pp.65-72
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• 2011

Purpose: The intention of this study was to investigate the effects of modified constraint-induced movement therapy (mCIMT) with bilateral arm training (BAT) on the motor performance and daily activity performance of individuals with chronic hemiparetic stroke. Methods: Sixteen subjects one year after stroke participated in this study with a control group; the pretest-posttest method was used. The subjects were randomly allocated into two groups: combination of bilateral arm training and modified constraint-induced movement therapy (n=8), and modified constraint-induced movement therapy (n=8). The mCIMT group received therapy for 90 minutes in 3 sessions per week over a period of 4 weeks. The patients receiving a combination of mCIMT and BAT were treated for the same period and frequency. The results were evaluated using the Fugl-Meyer Assessment, Action Research Arm Test (ARAT), and Motor Activity Log-Amount of Use, and Quality of Movement (MAL-AOU, QOM) assessment tools. Results: The Fugl-Meyer Assessment showed that hand and wrist performance improved significantly more in the mCIMT group than in the Combination group (p<0.05). Result from the ARAT assessment showed greater scores for gross movement in the combined group than in the mCIMT group (p<0.05). The MAL-AOU showed that there was greater improvement in the combined group than in the mCIMT group (p<0.05). Conclusion: The forced use of the more affected side can be important for the enhancement of upper extremity performance for chronic hemiparetic stroke patients during their daily activities.

• Journal of the Korean Ceramic Society
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• v.18 no.2
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• pp.119-125
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• 1981

The thermostable resistor was made by using P.T.C.R-N.T.C.R. ceramics. In this study $BaTiO_3$ type P.T.C.R. ceramics and $SnO_2-Sb_2O_3$ type N.T.C.R. ceramics were cocrystallized in one body and electrical resistance was stable under the temperature variation between $25^{\circ}C$-40$0^{\circ}C$. The ceramics showed the most stable electrical resistance for the mal variation when the composition was 0.6P.T.C.R. $BaTiO_3$,$ 0.4SnO_2$ and 0.01 $Sb_2O_3$.

• Knowledge Management Research
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• v.9 no.1
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• pp.147-161
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• 2008

In the previous KM (Knowledge Management) studies, it has been repeatedly pointed that CoP (Community of Practice) should be used as a platform for boosting up corporate innovative activities. Despite this, it is very rare to find relevant literature in which real-world cases are introduced showing critical success factors, implemented strategies, and objective analysis of results. In this sense, main objective of this paper is very timely- to introduce a real-world CoP case in which POSCO, world-leading steel company, sorted out creative CoP strategies to nurture knowledge-sharing activities to solve various kinds of problems at hand, and maintain appropriate level of knowledge circulation throughout all the working units of company. In a nutshell, POSCO has been successful in any measure in utilizing the creative CoP activities as strategic means to change the paradigm of innovation and extract fruitful outcomes from integrating three important individual activities such as work, learning, and innovation.

• The Journal of the Korean Society for Microbiology
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• v.35 no.5_6
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• pp.352-352
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• 2000