• Title/Summary/Keyword: magnetic susceptibility analysis

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Diagnostic Value of Susceptibility-Weighted MRI in Differentiating Cerebellopontine Angle Schwannoma from Meningioma

  • Seo, Minkook;Choi, Yangsean;Lee, Song;Kim, Bum-soo;Jang, Jinhee;Shin, Na-Young;Jung, So-Lyung;Ahn, Kook-Jin
    • Investigative Magnetic Resonance Imaging
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    • v.24 no.1
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    • pp.38-45
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    • 2020
  • Background: Differentiation of cerebellopontine angle (CPA) schwannoma from meningioma is often a difficult process to identify. Purpose: To identify imaging features for distinguishing CPA schwannoma from meningioma and to investigate the usefulness of susceptibility-weighted imaging (SWI) in differentiating them. Materials and Methods: Between March 2010 and January 2015, this study pathologically confirmed 11 meningiomas and 20 schwannomas involving CPA with preoperative SWI were retrospectively reviewed. Generally, the following MRI features were evaluated: 1) maximal diameter on axial image, 2) angle between tumor border and adjacent petrous bone, 3) presence of intratumoral dark signal intensity on SWI, 4) tumor consistency, 5) blood-fluid level, 6) involvement of internal auditory canal (IAC), 7) dural tail, and 8) involvement of adjacent intracranial space. On CT, 1) presence of dilatation of IAC, 2) intratumoral calcification, and 3) adjacent hyperostosis were evaluated. All features were compared using Chi-squared tests and Fisher's exact tests. The univariate and multivariate logistic regression analysis were performed to identify imaging features that differentiate both tumors. Results: The results noted that schwannomas more frequently demonstrated dark spots on SWI (P = 0.025), cystic consistency (P = 0.034), and globular angle (P = 0.008); schwannomas showed more dilatation of internal auditory meatus and lack of calcification (P = 0.008 and P = 0.02, respectively). However, it was shown that dural tail was more common in meningiomas (P < 0.007). In general, dark spots on SWI and dural tail remained significant in multivariate analysis (P = 0.037 and P = 0.012, respectively). In this case, the combination of two features showed a sensitivity and specificity of 80% and 100% respectively, with an area under the receiver operating characteristic curve of 0.9. Conclusion: In conclusion, dark spots on SWI were found to be helpful in differentiating CPA schwannoma from meningioma. It is noted that combining dural tail with dark spots on SWI yielded strong diagnostic value in differentiating both tumors.

Sedimentary Characteristics and Chronology of Loess-paleosol Sequence in Jeongjang-ri, Geochang basin, Gyeongnam Province (경남 거창분지 정창리 뢰스-고토양 연속층의 퇴적물 특성과 편년)

  • Hwang, Sang-Ill;Kang, Chang-Hyeok;Yoon, Soon-Ock
    • Journal of the Korean Geographical Society
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    • v.46 no.1
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    • pp.1-19
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    • 2011
  • The physical and chemical characteristics of loess-paleosol sequence in Jeongjang-ri, Geochang basin are examined using the magnetic susceptibility measurement, grain size analysis, OSL age dating, major, rare earth and trace elements analysis. The grain size characteristics of the loess-palesol sequence are obviously different from those of river sediment forming river terrace deposits and the Chinese Loess Plateau. The loess-paleosol sequence consisting of L1, L1LL1, L1S1, L1L2, S1 and L2 from top to bottom is estimated to MIS 2~MIS 6 and the river terrace to MIS 7. The compositions of major, rare earth and trace elements indicate that the sequence show more weathered characteristics than the Chinese Loess Plateau and originated from the Chinese Loess Plateau. These features are in harmony with the previous studies in Korea.

A Study on the Material Characteristics of Stone Tools Excavated from the Remain Point of Paleolithic Age in Osong Site, Cheongju

  • Kim, Jae Hwan;Han, Min Su
    • Journal of Conservation Science
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    • v.35 no.1
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    • pp.41-49
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    • 2019
  • This study analyzes the material characteristics of stone tools of the Paleolithic period excavated from the Osong site, located at the project site for the creation of the Osong 2nd Life Science Complex, and estimates the provenance of the stone materials. Because the stones had been buried for a long time, their surfaces had become heavily weathered yellow or yellowish-brown, and the magnetic susceptibility values varied from 0 to 15(${\times}10^{-3}SI$). The excavated stone tools were rocks with various magnetic susceptibility values that could not be specified. Five stone tools subjected to destructive analysis were divided into two groups, one with a value of 1-3(${\times}10^{-3}SI$) and the other with a value of 5-9(${\times}10^{-3}SI$), both based on visible characteristics. The results of the thin-section analysis showed that most of the stone tools were basaltic rocks comprising plagioclase, quartz, and pyroxene, and some had iron content as high as 20 wt.%. These findings and the present geological map suggest that the stone tools were not made from the surrounding rocks because there are no areas containing basaltic rocks surrounding Bongsan-ri in Osong-eup. Andesite and tuff are distributed along with basaltic rocks in the Doan-myeon area in Jeongpyeong-gun, Chungcheongbuk-do Province, but the distance from the excavation site is too far. To determine whether this region is actually related to the provenance of the raw rock, it is necessary to conduct additional field surveys and comprehensive and precise analyses.

Preparation and Properties of Co$_{9-x}M_xS_8$(M = Ni, Rh, Ru, and Fe)

  • Kim, Kwan
    • Bulletin of the Korean Chemical Society
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    • v.7 no.2
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    • pp.102-105
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    • 1986
  • Samples with the nominal composition of $Co_{9-x}M_xS_8$(M = Ni, Rh, Ru, and Fe) were prepared, and their magnetic properties were measured. X-ray diffraction analysis showed that small amount of the elements Ni, Rh, and Fe could be incorporated into $Co_9S_8$ forming a homogeneous ${\pi}$-phase, whereas the Ru-incorporated sample could not be prepared in a single phase. The lattice parameter was observed to increase as other elements were incorporated into $Co_9S_8$. Samples incorporated with the elements of Ni, Rh, and Ru showed Pauli-paramagnetism while the Fe-incorporated sample exhibited weak ferromagnetism. The values of magnetic susceptibility for the Ni, Rh, Ru-incorporated samples were nearly the same as that of pure $Co_9S_8$.

Added Value of Contrast Leakage Information over the CBV Value of DSC Perfusion MRI to Differentiate between Pseudoprogression and True Progression after Concurrent Chemoradiotherapy in Glioblastoma Patients

  • Pak, Elena;Choi, Seung Hong;Park, Chul-Kee;Kim, Tae Min;Park, Sung-Hye;Won, Jae-Kyung;Lee, Joo Ho;Lee, Soon-Tae;Hwang, Inpyeong;Yoo, Roh-Eul;Kang, Koung Mi;Yun, Tae Jin
    • Investigative Magnetic Resonance Imaging
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    • v.26 no.1
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    • pp.10-19
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    • 2022
  • Purpose: To evaluate whether the added value of contrast leakage information from dynamic susceptibility contrast magnetic resonance imaging (DSC MRI) is a better prognostic imaging biomarker than the cerebral blood volume (CBV) value in distinguishing true progression from pseudoprogression in glioblastoma patients. Materials and Methods: Forty-nine glioblastoma patients who had undergone MRI after concurrent chemoradiotherapy with temozolomide were enrolled in this retrospective study. Twenty features were extracted from the normalized relative CBV (nCBV) and extraction fraction (EF) map of the contrast-enhancing region in each patient. After univariable analysis, we used multivariable stepwise logistic regression analysis to identify significant predictors for differentiating between pseudoprogression and true progression. Receiver operating characteristic (ROC) analysis was employed to determine the best cutoff values for the nCBV and EF features. Finally, leave-one-out cross-validation was used to validate the best predictor in differentiating between true progression and pseudoprogression. Results: Multivariable stepwise logistic regression analysis showed that MGMT (O6-methylguanine-DNA methyltransferase) and EF max were independent differentiating variables (P = 0.004 and P = 0.02, respectively). ROC analysis yielded the best cutoff value of 95.75 for the EF max value for differentiating the two groups (sensitivity, 61%; specificity, 84.6%; AUC, 0.681 ± 0.08; 95% CI, 0.524-0.837; P = 0.03). In the leave-one-out cross-validation of the EF max value, the cross-validated values for predicting true progression and pseudoprogression accuracies were 69.4% and 71.4%, respectively. Conclusion: We demonstrated that contrast leakage information parameter from DSC MRI showed significance in differentiating true progression from pseudoprogression in glioblastoma patients.

Effective Gray-white Matter Segmentation Method based on Physical Contrast Enhancement in an MR Brain Images (MR 뇌 영상에서 물리기반 영상 개선 작업을 통한 효율적인 회백질 경계 검출 방법)

  • Eun, Sung-Jong;Whangbo, Taeg-Keun
    • Journal of Digital Contents Society
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    • v.14 no.2
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    • pp.275-282
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    • 2013
  • In medical image processing field, object recognition is usually carried out by computerized processing of various input information such as brightness, shape, and pattern. If the information mentioned does not make sense, however, many limitations could occur with object recognition during computer processing. Therefore, this paper suggests effective object recognition method based on the magnetic resonance (MR) theory to resolve the basic limitations in computer processing. We propose the efficient method of robust gray-white matter segmentation by texture analysis through the Susceptibility Weighted Imaging (SWI) for contrast enhancement. As a result, an average area difference of 5.2%, which was higher than the accuracy of conventional region segmentation algorithm, was obtained.

Determination of Strongly Interacting Spin Exchange Path and Spin Lattice Model of (VO)2(H2O){O3P-(CH2)3-PO3}ㆍ2H2O on the Basis of Spin Dimer Analysis

  • Kim, Dae-Hyun;Koo, Hyun-Joo
    • Bulletin of the Korean Chemical Society
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    • v.31 no.6
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    • pp.1665-1668
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    • 2010
  • The spin exchange interactions of $(VO)_2(H_2O){O_3P-(CH_2)_3-PO_3}{\cdot}2H_2O$ were examined by spin dimer analysis based on extended Huckel tight binding method. The strongest spin exchange interaction occurs through the super-superexchange path $J_2$ and the second strongest spin exchange interaction occurs through the superexchange interaction path $J_1$. There are two strongly interacting spin exchange paths in $(VO)_2(H_2O){O_3P-(CH_2)_3-PO_3}{\cdot}2H_2O$. Therefore, magnetic susceptibility curve of $(VO)_2(H_2O){O_3P-(CH_2)_3-PO_3}{\cdot}2H_2O$ can be well reproduced by an alternating onedimensional antiferromagnetic chain model rather than an isolated spin dimer model.

Differentiation between Glioblastoma and Primary Central Nervous System Lymphoma Using Dynamic Susceptibility Contrast-Enhanced Perfusion MR Imaging: Comparison Study of the Manual versus Semiautomatic Segmentation Method

  • Kim, Ye Eun;Choi, Seung Hong;Lee, Soon Tae;Kim, Tae Min;Park, Chul-Kee;Park, Sung-Hye;Kim, Il Han
    • Investigative Magnetic Resonance Imaging
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    • v.21 no.1
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    • pp.9-19
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    • 2017
  • Background: Normalized cerebral blood volume (nCBV) can be measured using manual or semiautomatic segmentation method. However, the difference in diagnostic performance on brain tumor differentiation between differently measured nCBV has not been evaluated. Purpose: To compare the diagnostic performance of manually obtained nCBV to that of semiautomatically obtained nCBV on glioblastoma (GBM) and primary central nervous system lymphoma (PCNSL) differentiation. Materials and Methods: Histopathologically confirmed forty GBM and eleven PCNSL patients underwent 3T MR imaging with dynamic susceptibility contrast-enhanced perfusion MR imaging before any treatment or biopsy. Based on the contrast-enhanced T1-weighted imaging, the mean nCBV (mCBV) was measured using the manual method (manual mCBV), random regions of interest (ROIs) placement by the observer, or the semiautomatic segmentation method (semiautomatic mCBV). The volume of enhancing portion of the tumor was also measured during semiautomatic segmentation process. T-test, ROC curve analysis, Fisher's exact test and multivariate regression analysis were performed to compare the value and evaluate the diagnostic performance of each parameter. Results: GBM showed a higher enhancing volume (P = 0.0307), a higher manual mCBV (P = 0.018) and a higher semiautomatic mCBV (P = 0.0111) than that of the PCNSL. Semiautomatic mCBV had the highest value (0.815) for the area under the curve (AUC), however, the AUCs of the three parameters were not significantly different from each other. The semiautomatic mCBV was the best independent predictor for the GBM and PCNSL differential diagnosis according to the stepwise multiple regression analysis. Conclusion: We found that the semiautomatic mCBV could be a better predictor than the manual mCBV for the GBM and PCNSL differentiation. We believe that the semiautomatic segmentation method can contribute to the advancement of perfusion based brain tumor evaluation.

Source rock investigation for the Gyeongju Seated Stone Buddha with Square Pedestals in the Blue House using nondestructive petrological analysis (청와대 소재 경주 방형대좌 석조여래좌상의 암석학적 비파괴분석을 통한 산지해석)

  • Lee, Myeong Seong;Yoo, Ji Hyun;Kim, Jiyoung
    • Journal of the Geological Society of Korea
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    • v.54 no.5
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    • pp.567-578
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    • 2018
  • A nondestructive petrological investigation was carried out to identify the original location and form of the Gyeongju Seated Stone Buddha with Square Pedestals in the Blue House (so-called Stone Buddha in the Blue House). The Statue is a representative stone Buddha statue of Silla (9th century) but its original location is controversial and some parts were missing. Based on the petrological observation, magnetic susceptibility and gamma spectrometry, its stone material was identified as medium-grained alkali feldspar granite. This kind of granites are widely found in the Namsan, Gyeongju. It is very likely that the Namsan granites are the source of rock of the Stone Buddha. The Yudeoksa (Igeosaji temple site) and Namsan are possible to be the original home of the Buddha Statue since there are petrologically identical alkali feldspar granite outcrop distributed in Namsan and stone heritage made of the same stone type in both places. An investigation on the square middle stone base in the Chuncheon National Museum reveals that it is less likely to be the missing part of the Buddha statue as the stone base is fine- to medium-grained pink feldspar granite and has different magnetic susceptibility from the Buddha statue. This study confirmed the contribution and significance of petrological investigation to identification of stone heritage in Korea.

Investigation on the inductive and resistive fault current limiting HTS power cable

  • Lee, Sangyoon;Choi, Jongho;Kim, Dongmin;Kwon, Yonghyun;Kim, Seokho;Sim, Kideok;Cho, Jeonwook
    • Progress in Superconductivity and Cryogenics
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    • v.16 no.2
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    • pp.59-63
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    • 2014
  • HTS power cable bypass the fault current through the former to protect superconducting tapes. On the other hand, the fault current limiting (FCL) power cable can be considered to mitigate the fault current using its increased inductance and resistance. Using the increased resistance of the cable is similar to the conventional resistive fault current limiter. In case of HTS power cable, the magnetic field of HTS power cable is mostly shielded by the induced current on the shield layer during normal operation. However, quench occurs at the shield layer and its current is kept below its critical current at the fault condition. Consequently, the magnetic field starts to spread out and it generates additional inductive impedance of the cable. The inductive impedance can be enhanced more by installing materials of high magnetic susceptibility around the HTS power cable. It is a concept of SFCL power cable. In this paper, a sample SFCL power cable is suggested and experimental results are presented to investigate the effect of iron cover on the impedance generation. The tests results are analyzed to verify the generation of the inductive and resistive impedance. The analysis results suggest the possible applications of the SFCL power cable to reduce the fault current in a real grid.