• 제목/요약/키워드: magnetic flux profiles

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Effect of Extremely Low Frequency Magnetic Fields on Gene Expression in Human Mammary Epithelial MCF10A Cells

  • Hong, Mi-Na;Lee, Hyung-Chul;Kim, Bong Cho;Lee, Yun-Sil;Gimm, Yoon-Myung;Myung, Sung-Ho;Lee, Jae-Seon
    • Journal of electromagnetic engineering and science
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    • 제12권4호
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    • pp.271-279
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    • 2012
  • The effects of extremely low frequency magnetic fields (ELF-MFs) on physiological processes at the cellular level remain unclear despite a number of studies. To investigate the effects of ELF-MFs on gene expression, we exposed human mammary epithelial MCF10A cells to fields of 1 mT magnetic flux density at 60 Hz for 4 and 16 h and measured the transcriptional responses of 24,000 genes using Illumina microarrays. In three independent experiments, we found no statistically significant alteration of expression levels for any of the genes assayed using a cutoff value of 1.2-fold. To confirm this result, we selected six genes with trends suggesting possible expression level changes, although these trends were not statistically significant, and investigated their expression levels further using a semiquantitative reverse-transcription polymerase chain reaction. In three independent experiments, we did not find any alterations in the expression levels of these genes. From these results, we conclude that ELF-MFs do not affect gene expression profiles under our exposure conditions.

Micro Hall probe array를 이용한 YBa$_2Cu_3O_7$ 단결정 내부의 자속 운동 측정 (Vortex dynamics in YBa$_2Cu_3O_7$ single crystals measured by micro Hall-probe array)

  • 심성엽;황현국;이창우;이태원;김동호
    • 한국초전도학회:학술대회논문집
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    • 한국초전도학회 1999년도 High Temperature Superconductivity Vol.IX
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    • pp.189-195
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    • 1999
  • We have studied the vortex dynamics in YBa$_2Cu_3O_7$ single crystals with columnar defects using micro Hall-probe array. The Hall-probe array technique allowed a simultaneous measurement of the time and spatial dependence of the vortex density so that more detailed information on flux dynamics could be obtained. We found that field profiles inside sample were similar to the Bean's critical state model from the magnetic hysteresis measurement. Normalized relaxation rates were maximum near the center and decreased toward the edge if applied field H$_{app}$ is greater than the penetration field H. But applied magnetic field H$_{app}$ is less than H, relaxation rates were minimum near the center and increased toward edge. We found that glassy exponent ${\mu}$ has the value of ${\sim}$ 1 whose corresponding vortex motion is half-loop excitation. However, single vortex creep, ${\mu}$ ${\sim}$ 1/7, was also found at 30 K and H$_{app}$ ${\cong}$ H'. Calculation of activation energy, U, was possible from direct analysis of the local relaxation data using the basic diffusion equation. From these results, we found that U increases logarithmically with time and U around center was lower than that at the edge.

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