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Gamakamide-E, a Strongly Bitter Tasting Cyclic Peptide with a Hydantoin Structure from Cultured Oysters Crassostrea gigas

  • Lee, Jong-Soo;Satake, Masayuki;Horigome, Yoichi;Oshima, Yasukatsu;Yasumoto, Takeshi
    • Fisheries and Aquatic Sciences
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    • v.15 no.1
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    • pp.15-19
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    • 2012
  • A new cyclic peptide (six-membered amino acid), gamakamide-E (L-Leu-L-Met (SO)-L-Me-Phe-L-Leu-D-Lys-L-Phe), was isolated as a strongly bitter tasting compound from cultured oysters, Crassostrea gigas. The molecular formula of $C_{43}H_{61}N_7O_8S$ was deduced from high resolution fast atom bombardment mass spectrometry (HR FAB-MS) ($[M+H]^+$ m/z 836.4356 ${\Delta}$= -2.4 mmu). Its unique structure including a hydantoin structure was firstly elucidated by nuclear magnetic resonance (NMR) analysis. Stereochemistries of constituent amino acids were determined by chiral high performanced liquid chromatography analysis of natural and synthesized peptides.

A Study of Nanoscale Structure of Anodic Porous Alumina film (다공성 알루미나 박막의 나노 스케일 구조에 관한 연구)

  • 정경한;신훈규;권영수
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.16 no.9
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    • pp.801-806
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    • 2003
  • In recent years, there has been large interest in the fabrication of the self organized nanoscale structures since not only their potential utilization in electronic, optoelectronic, and magnetic devices but also their fundamental interest such as uniformity and regularization. An attractive candidate of these materials is anodic porous alumina film(Al$_2$O$_3$) which is formed by the anodization of aluminum in an appropriate acid solution. In this study to fabricate the porous alumina film with very uniform and nearly parallel pores the anodization was carried out under constant voltage mode in 0.3M oxalic acid as an electrolyte. The hexagonally ordered arrays with a few $\mu\textrm{m}$ in size two-dimensional polycrystalline structure were obtained of which pore densities were 1.1${\times}$10$\^$10//$\textrm{cm}^2$.

The Effects of Genotype, Density and Irradiance on the Growth and Mortality of the Brown Seeweed serratus Germlings

  • Choi, Han-Gil
    • Animal cells and systems
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    • v.7 no.2
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    • pp.127-132
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    • 2003
  • Effects of genotype, settlement density and irradiane on the growth, mortality and population structure of Fucus serratus germlings were examined in the laboratory. The growth of F. serratus germlings was influenced by genotype of parent plants, which is likely to occur by microclimatic differentiation of substrata. The growth of germlings were greater at lower densities than higher densities indicating that intraspecific competition between germlings occurred within three weeks. Also, the growth of F. serratus germlings was better at $120\mumol\;m^-2/s^-1$ than at $60\mumol\;m^-2/s^-1$. However, mortality of germlings was determined by settlement density rather than irradiance. In population structure, skewness was increased at low irradiance and high density indicating that population structure could be changed by intraspecific competition. Thus, it is concluded that genotypic differentiation of F. serratus germlings occurred in a microgeographic scale, and the experimental density and irradiance level affected the growth of germlings.

Crystal Structure of Pentapotassium Disodium Hexatungstoantimonate(V) Dodecahydrate, $K_5Na_2[SbW_6O_{24}]\cdot12H_2O$

  • Lee, Uk;Sasaki, Yukiyoshi
    • Bulletin of the Korean Chemical Society
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    • v.8 no.1
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    • pp.1-3
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    • 1987
  • The crystal structure of $K_5Na_2[SbW_6O_{24}]{\cdot}12H_2O$ has been determined. Final R = 0.081 for 890 observed independent reflections collected by diffractometry. Crystal data as follows; trigonal, space group R3m, a = 9.794(1) ${\AA},\;{\alpha}$ = 84.72$(1)^{\circ}$, Z = 1. The heteropolyanion has a structure with point symmetry $D_{3d}$ (3m), of the ideal Anderson-type heteropolyanion. The Sb-W and W-W distances are 3.259(2) and 3.259(3) ${\AA}$. Three types of W-O ($W-O_t,\;W-O_b\;and\;W-O_c$) distances are 1.73(2), 1.95(4) and 2.20(3) ${\AA}$. The Sb-O distance is 1.97(3) ${\AA}$.

A Flip Chip Process Using an Interlocking-Joint Structure Locally Surrounded by Non-conductive Adhesive (비전도성 접착제로 국부적으로 둘러싸인 인터록킹 접속구조를 이용한 플립칩 공정)

  • Choi, Jung-Yeol;Oh, Tae-Sung
    • Korean Journal of Metals and Materials
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    • v.50 no.10
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    • pp.785-792
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    • 2012
  • A new flip chip structure consisting of interlocking joints locally surrounded by non-conductive adhesive was investigated in order to improve the contact resistance characteristics and prevent the parasitic capacitance increase. The average contact resistance of the interlocking joints was substantially reduced from $135m{\Omega}$ to $79m{\Omega}$ by increasing the flip chip bonding pressure from 85 MPa to 185 MPa. Improvement of the contact resistance characteristics at higher bonding pressure was attributed not only to the increased contact area between Cu chip bumps and Sn pads, but also to the severe plastic deformation of Sn pads caused during formation of the interlocking-joint structure. The parasitic capacitance increase due to the non-conductive adhesive locally surrounding the flip chip joints was estimated to be as small as 12.5%.

Synthesis and Crystal Structure of $UP_{2}S_{6}$

  • Do, Jung-Hwan;Kim, Jung-Wook;Lah, Sang-Moo;Yun, Ho-Seop
    • Bulletin of the Korean Chemical Society
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    • v.14 no.6
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    • pp.678-681
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    • 1993
  • The new ternary phase $UP_2S_6$ has been prepared and structurally characterized. The compound is isostructural with $ZrP_2S_6$ and $ThP_2S_6$ but is different from $TiP_2S_6$. The structure has been determined by a single crystal X-ray diffraction technique. $UP_2S_6$ crystallizes in the the tetragonal system $({C^2}_{4h}-P4_2/m,\;a=6.797(7)\;{\AA},\;c=9.738(12)\;{\AA})$ with two formula units in the unit cell. The structure can be described in terms of $U^{4+}$ and ${P_2S_6}^{4-}$ ions. This hexathiohypodiphosphate anion $({P_2S_6}^{4-})$ has ideally staggered conformation. The $U^{4+}$ cation is coordinated by 8 sulfur atoms in a slightly distorted dodecahedral geometry (42m). The distribution of sulfur atoms is very well optimized for this geometry.

The Study of Gain Optimization of Sliding Model Controller with Sliding Perturbation Observer by using of Genetic Algorithm

  • K.S. You;Park, M.K.;Lee, M.C.
    • 제어로봇시스템학회:학술대회논문집
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    • 2000.10a
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    • pp.495-495
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    • 2000
  • The Stewart platform manipulator is a closed-kinematis chain robot manipulator that is capable of providing high st겨ctural rigidity and positional accuracy. However, this is a complex structure, so controllability of the system is not so good. In this paper, it introduces a new robust motion control algorithm using partial state feedback for a class of nonlinear systems in the presence of modelling uncertainties and external disturbances. The major contribution of this work introduces the development and design of robust observer for the slate and the perturbation w.hich is integrated into a variable structure controller(VSC) structure. The combination of controller/observer gives rise to the robust routine called sliding mode control with sliding perturbation observer(SMCSPO). The optimal gains of SMCSPO are easily obtained by genetic algorithm. Simulation and experiment are presented in order to apply to the stewart platform manipulator. There results show highly' accuracy and performance.

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Development a data base structure for a die/tool coding system

  • Rho, H.M.;Shin, D.M.;Lee, C.W.;Fukuda, Y.;Kiyosawa, F.
    • Journal of the Korean Society for Precision Engineering
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    • v.5 no.2
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    • pp.56-61
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    • 1988
  • For the use of computer to store, modify and retieve technical data, GT coding system has been considered as one of the effective methods. Effective data management is important for Computer Intergrated Manufacturing. Based on actual data obtained from a hand-tool maker, a die/tool coding system is developed as an example and its data base is designed susing a linked list structure. It is suggested that industries use this method to make their own data base.

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A Study on the Stand Structure Analysis by the Changing Growth in Korean White Pine Stand (잣나무 임분의 생장변화에 따른 임분구조 해석에 관한 연구 - 강원대학교 학술림을 중심으로 -)

  • Jang, Jae-Young;Shin, Hyun-Ji;Woo, Jong-Choon
    • Journal of Forest and Environmental Science
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    • v.20 no.1
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    • pp.58-68
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    • 2004
  • In this study, the stand structure of the Korean White Pine stand is analysed by the changing growth situation and the growth model for DBH, Height, and Volume per ha, which is estimated with the data collected for Korean White Pine stand in the Research Forests of Kangwon National University. The results were summarized as follows The estimated equations were (1) Y=20.687Ln(X)-50.431 for DBH, (2) Y=12.951Ln(X)-31.225 for Height, (3) Y=171.06Ln(X)-462.16 for Volume per ha. The mean volumes per ha according to the age classes using the estimated equations were $27.45m^3$ $91.05m^3$, $147.71m^3$, $190.03m^3$, $223.84m^3$, $252.01m^3$ and $276.15m^3$ for the age class II, III, IV, V, VI, VII and VIII, respectively. And also, the relationship between mean annual increment(MAI) and periodic average increment(PAI) was analysed.

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A Study on Evacuation Time According to Seafarer Visibility (선원들의 가시거리별 피난시간 연구)

  • Kim, Won-Ouk
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.22 no.6
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    • pp.600-606
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    • 2016
  • Seafarers are often placed in circumstances that require emergency evacuations due to various causes, including ship collisions, sinking, stranding, and fires. Achieving shorter evacuation time is an important factor in increasing the survival rate during these circumstances, but the narrow and complicated structure of ships is an obstacle when it comes to executing a quick evacuation. Also, unpredictable restrictions may be imposed by bad sea or weather. In this study, various experiments were conducted with sailors currently on board ships in order to examine factors that increase evacuation time. The data was then and analyzed. Evacuation time was measured by dividing crews into groups: sailors that were given an explanation of the ship's structure and those that were not. Furthermore, the visibility range was divided into 0 m, 3 m, and 5 m. The results indicated that, having an explanation of the ship structure did not have much of an effect on evacuation time but visibility conditions led to an increase in evacuation time with a maximum of 2.5 to 2.6 times longer when the visible distance was 5 m, 0 m and 3 m. Therefore, ensuring a visible distance of over 5 m was determined to be the most important factor for reducing evacuation time. In the future, effort should be made to ensure a greater visible distance to improve the survival rate of seafarers and passengers on board ships that encounter incidents.