• BMB Reports
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• v.44 no.3
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• pp.147-157
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• 2011

The meiotic process from the primordial stage to zygote in female germ cells is mainly adjusted by post-transcriptional regulation of pre-existing maternal mRNA and post-translational modification of proteins. Several key proteins such as the cell cycle regulator, Cdk1/cyclin B, are post-translationally modified for precise control of meiotic progression. The second messenger (cAMP), kinases (PKA, Akt, MAPK, Aurora A, CaMK II, etc), phosphatases (Cdc25, Cdc14), and other proteins (G-protein coupled receptor, phosphodiesterase) are directly or indirectly involved in this process. Many proteins, such as CPEB, maskin, eIF4E, eIF4G, 4E-BP, and 4E-T, post-transcriptionally regulate mRNA via binding to the cap structure at the 5' end of mRNA or its 3' untranslated region (UTR) to generate a closed-loop structure. The 3' UTR of the transcript is also implicated in post-transcriptional regulation through an association with proteins such as CPEB, CPSF, GLD-2, PARN, and Dazl to modulate poly(A) tail length. RNA interfering is a new regulatory mechanism of the amount of mRNA in the mouse oocyte. This review summarizes information about post-transcriptional and post-translational regulation during mouse oocyte meiotic maturation.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.35 no.2
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• pp.196-200
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• 1999

In the case that erosion and corrosion occurs in machinery and structure at the same time, the synergy effect by erosion-corrosion affects fatal effect to durability of machinery and structure. Therefore, in machinery and structure which use corrosion liquid, the study of the synergy effect of erosion-corrosion which affects metal material is requested. In this paper. the flow corrosion experiment about the effect of temperature change and liquid velocity change in sea water was carried out to study the characteristics of erosion-corrosion for tube material Cu heat exchanger The main results obtained are as follows. (1) Damage appearance of tube outside by erosion-corrosion becomes dull because electrode potentials of Cu tube is higher than electrode potential of STPG38 shell. (2) In the cooling system by sea water, the weight loss rate of Cu at tube outside liquid temperature of $70^{\circ}C$ is higher than that of temperature of $20^{\circ}C$. (3) In cooling system by sea water, the weight loss rate of Cu at liquid velocity of 5.1m/s is higher than that of velocity of 1.47m/s. But as the testing time passed, the weight loss rate of Cu at velocity of 5.1m/s is almost steady and becomes dull at velocity of 1.47m/s.

• Korean Journal of Environment and Ecology
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• v.18 no.2
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• pp.131-141
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• 2004

To investigate the vegetation structure of mountain ridge from Namdeogyusan to Sosajae in Baekdudaegan which is the greatest chain as well as the major ecological axix of the Korean Peninsula, sixteen sites(size 500$m^2$) were set up and surveyed. By using TWINSPAN technique, the plants community was divided and summarized into five groups, those are four Quercus mongolica dominated communities and Quercus mongolica-Pinus densiflora community. Four Quercus mongolica dominated communities have differentiated from subtree dominant species. Vegetation structure of each community have explained using important percentage by layer. In descriptive analysis, average number of species is 27.8$\pm$7.5 and average number of individuals is 687.6$\pm$326.8 at unit area(500$m^2$).

• Structural Engineering and Mechanics
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• v.53 no.1
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• pp.73-87
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• 2015

In case of aircraft impact on nuclear containment structures, the initial kinetic energy of the aircraft is transferred and absorbed by the outer containment, may causing either complete or partial failure of containment structure. In the present study safety analysis of BWR Mark III type containment has been performed. The total height of containment is 67 m. It has a circular wall with monolithic dome of 21m diameter. Crash analysis has been performed for fighter jet Phantom F4. A normal hit at the crown of containment dome has been considered. Numerical simulations have been carried out using finite element code ABAQUS/Explicit. Concrete Damage Plasticity model have been incorporated to simulate the behaviour of concrete at high strain rate, while Johnson-Cook elasto-visco model of ductile metals have been used for steel reinforcement. Maximum deformation in the containment building has reported as 33.35 mm against crash of Phantom F4. Deformations in concrete and reinforcements have been localised to the impact region. Moreover, no significant global damage has been observed in structure. It may be concluded from the present study that at higher velocity of aircraft perforation of the structure may happen.

• Korean Journal of Environment and Ecology
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• v.7 no.2
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• pp.172-180
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• 1994

The forest of Choksangsansong area was studied to investigate vegetational structure with twenty-five plots(20m$\times$25m). Relative importance values, DBH class distribution, species, diversity indices, DCA ordination and TWINSPAN classification were used for vegetational structure analysis. Quercus mongolica, Carpinus cordata, Quercus serrata and Cornus controversa were appeared to be dominant species in each plot and dominant species in the Choksangsansong area was Quercus mongolica. The forest of Choksangsansong area was classified into four groups and showed seral stage from Quercus mongolica to Carpinus cordata. Vegetational succession in the Choksangsansong area shall be accelerated to moist and shade tolerant species due to cool and humid climatic condition by upper dam construction of the Mujuyangspalchonso (pumping up power station).

• Tribology and Lubricants
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• v.4 no.2
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• pp.36-43
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• 1988

Titanium carbide(TiC) and titanium nitride(TiN) flims were deposited on $Si_3N_4$-TiC composite cutting tools by chemical vapor deposition(CVD) using $TiCl_4-CH_4-H_2$ and $TiCl_4-H_2-N_2$ gas mixtures, respectively. The nonmetal to metal ratio of deposit increases with increasing $m_{C/Ti}$(mole ratio of CH$_4$ to TiCl$_4$ in the input) for TiC coatings and $m_{N/Ti}$(mole ratio of N$_2$ to TiCl$_4$ in the input) for TiN coatings. The nearly stoiahiometric films could be obtained under the deposition condition of $m_{C/Ti}$ between 1.15 and 1.61 for TiC, and that of $m_{N/Ti}$ between 25 and 28 for TiN. Also maximum microhardness of the coatings can be obtained in these ranges. The interfacial region of TiC coatings on $Si_3N_4$-TiC ceramics is wider than that of TiN coatings according to Auger depth profile analysis, which indicates good interfacial bonding for TiC. Experimental results show that TiC coatings have an randomly equiaxed structure and Columnar structure with(220) preferred orientation can be obtained for TiN coatings. And, multilayer coatings have a dense and equiaxed structure.

• Journal of The Geomorphological Association of Korea
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• v.24 no.3
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• pp.47-59
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• 2017

This study aims to analyze geomorphologically Jaein Falls in Hantangang Lava Plateau for the landform structure, landform classification, falls dissection and recession. The height and recession length of the Falls are approximately 18m and 340m. after dissection valley arrive at area of the Jijangbong Volcanic Rock Complex of Mesozoic era, the fall will disappear. The structure of the dissection valley shows totally well vertical columnar joint near falls and plunge pool, colluvial talus deposits toward lower reach by the freezing-thawing and wet-dry activities, and alluvial cone and delta in estuary to Hantangang River. The Falls' age date and recession rate in the valley maybe relate to the age of the lava plateau. The estimated recession rate of the fall should be 8.75m/ka to 2.3m/ka, depending on the age 500ka to 40ka in lava plateau.

• International conference on construction engineering and project management
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• 2020.12a
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• pp.30-37
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• 2020

In the building construction, the steel-frame work occupies an important position in terms of structure, cost and quality. Especially in Japan, steel frames have traditionally been the main structure of many buildings. For steel-frame works in such positions, this paper investigates an existing steel fabricator to clarify the actual conditions of design decision making process and management method in steel production process. This study focuses on a steel fabricator (Company M in the following sentences), whose main market is Japan and which has facilities in Thailand, China, and Japan. Company M uses QR codes to control the production status of products, and exchanges all information between inside and outside the company via specialized departments in the form of documents. The authors have already analyzed the relationship between production lead time and defect rate based on actual project data at Architectural Institute of Japan in 2016. In 2019, we expressed the process from the confirmation of the design information of the current steel frame to the production by WBS, and clarified the relationship between the production lead time and steel frame product quality structurally. In this paper, the authors reoport the progress of the survey conducted so far, the positioning of the collected data, and the future survey policy.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.26 no.2
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• pp.196-203
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• 2015

In order to apply cylindrical periodic array to phased array antenna or frequency selective surface, efficient electromagnetic analysis is required. Finite periodic array is applied in real situation. But, generally, assumed that periodic structure is arranged infinitely, approximate electromagnetic characteristics can be obtained efficiently. But, difference of characteristics between real structure and approximate structure occurs because finite periodic array is approximated to infinite periodic array. Therefore, comparison and analysis of cylindrical infinite array and finite array are required. In this paper, cylindrical infinite periodic array are analyzed using cylindrical Floquet harmonics. Also, cylindrical finite periodic array is analyzed using method of moments (MoM) with thin wire approximation because periodic structures which are composed of strip with narrow width are analyzed. Transmission characteristics and surface currents of infinite and finite periodic structures are compared.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7473-7482
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• 2013

The G-protein coupled receptor 87 (GPR87) is a recently discovered orphan GPCR which means that the search of their endogenous ligands has been a novel challenge. GPR87 has been shown to be overexpressed in squamous cell carcinomas (SCCs) or adenocarcinomas in lungs and bladder. The 3D structure of GPR87 was here modeled using two templates (2VT4 and 2ZIY) by a threading method. Functional assignment of GPR87 by SVM revealed that along with transporter activity, various novel functions were predicted. The 3D structure was further validated by comparison with structural features of the templates through Verify-3D, ProSA and ERRAT for determining correct stereochemical parameters. The resulting model was evaluated by Ramachandran plot and good 3D structure compatibility was evidenced by DOPE score. Molecular dynamics simulation and solvation of protein were studied through explicit spherical boundaries with a harmonic restraint membrane water system. A DRY-motif (Asp-Arg-Tyr sequence) was found at the end of transmembrane helix3, where GPCR binds and thus activation of signals is transduced. In a search for better inhibitors of GPR87, in silico modification of some substrate ligands was carried out to form polar interactions with Arg115 and Lys296. Thus, this study provides early insights into the structure of a major drug target for SCCs.