• 대한물리치료과학회지
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• 제10권1호
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• pp.47-57
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• 2003

The purpose of this study was to evaluate the problem on activities of daily living ; the problem which spinal cord injured patients have when they adapt in daily living ; Subjects were 113 members who used the hospital which is located in Kwangju-city from November 20, 2001 to May 20, 2002. The evaluation of the ADL was performed according to MBI and collected data were statistically analysed by SPSS PC for paired Chi-square test T-test, One way ANOVA and Duncan's post-hoc test. The result's were as follows; 1. Modified Barthel Index average mark was $63.77{\pm}33.60$ points and MBI score distribution according to characteristics of injury is as following. 1) A patient who had long duration of injury, small injury region, incomplete paralysis in paralysis degree, paraplegia in paralysis type got high MBI score as statistical and significantly(p<0.05). 2. Society adaptation state by characteristics of spinal cord injured is an following. 1) After lapse of time of disease, a patient who is injured for a long term present surrounding environmental problem, a patient who is injured for a short term shows psychological problem. In society activity, as lapse of time of disease is long, patient did many hobby activity and same private club, on the other hand as lapse of time of diseases is short, the others appeared high and significantly as statistical(p<0.01). 2) In society activity by injury region, cervical injury and thoracic injury did more hobby activity than lumbar injury and in lumbar injury same private club or religion life appeared higher than thoracic injury of cervical injury significantly as statistical(p<0.01). 3) In walk method by paralysis degree Complete paralysis had more wheelchair life than incomplete paralysis(p<0.01). 4) In serious problem by paralysis type psychological problem in quadriplegia and surrounding environmental problem in paraplegia appeared high and significantly as statistical(p<0.01). 3. In society adaptation state by MBI score difference between variables appeared but it wasn't significantly.

• 융합정보논문지
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• 제10권2호
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• pp.184-192
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• 2020

본 연구는 척추측만증 수술에 대한 객관적이고 정량적인 효과 평가 수단으로서 스마트 깔창을 이용한 보행분석 방법(시계열 분석 포함)을 제시한다. 실험 참가자는 척추측만증 환자이며 스마트 깔창을 착용하고 3분 보행검사를 4번(수술전, 수술 후 8일, 16일, 204일), 6분 보행검사를 1번(수술 후 204일) 받았다. 깔창에는 8개의 압력센서, 가속도 및 각속도 센서가 있고, 각각의 측정값을 저장하여 환자의 수술 전후 보행특성(운동역학 및 시공간 변수)을 비교하였다. 분석결과 수술 후 환자의 모든 보행변수가 개선된 것을 알 수 있었고, 6개월 후 추적검사에서 환자의 보행이 더욱 안정된 것을 확인할 수 있었다. 하지만 환자가 오래 걸으면 한쪽 다리의 swing 시간이 다른 쪽에 비해 미세하게 짧은 현상이 다시 나타났는데, 이는 검사를 수행하는 의사의 육안으로는 발견할 수 없는 preclinical한 문제였다. 우리는 이러한 분석 방법을 통해 환자의 개선 정도를 정량적이고 객관적으로 평가할 수 있었고, preclinical한 문제도 찾을 수 있었다. 향후 이러한 분석 방법은 특정 질병의 보행 패턴을 정의하고 감별하여 적절한 치료방법을 결정하는 연구로 이어질 것이다.

• 한국컴퓨터정보학회논문지
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• 제26권8호
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• pp.209-220
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• 2021

지방제외체질량(lean mass) 및 지방량(fat mass)과 같은 체성분이 골밀도에 미치는 영향은 매우 복잡하고 다양하게 나타나는 것으로 알려져 있다. 본 연구에서는 전국민을 대상으로 한 표본조사로부터 얻은 질병관리본부의 국민건강영양조사 2008-2011년 자료를 이용하여 50세 이상 남성(N=2,139) 및 폐경후여성(N=2,193)에서 체성분과 골밀도와의 관련성에 대해 조사하고자 하였다. 골다공증약물을 사용한 경우 및 골밀도에 영향을 미치는 질환 및 악성질환 등이 있는 대상은 제외하였다. 신체계측, 설문조사, 혈액검사 등과 함께 이중에너지흡수방사선을 이용하여 요추 및 대퇴골에서 골밀도를 측정하였고, 총지방제외체질량(TLM; total lean mass), 총지방량(TFM; total fat mass), 몸통지방량(TrFM; truncal fat mass) 등을 측정하였다. 체성분 지표들과 요추 및 대퇴골 골밀도는 유의한 양의 상관관계를 보였다. 연령, 체질량지수, 월 가구수입, 교육수준, 신체활동, 1일 칼슘섭취량, 혈중 비타민 D 농도를 포함하는 다중회귀분석을 시행한 결과 남녀 모두에서 TLM이 증가할수록 요추 및 대퇴골 골밀도가 유의하게 증가하였다. TLM의 가장 낮은 사분위수에 해당하는 군에서 요추 및 대퇴골 골밀도는 남녀 모두에서 다른 사분위수에 해당하는 군에 비해 유의하게 낮았다. TrFM은 위의 교란요인들을 보정한 이후 남성에서는 대퇴골전체 골밀도와 여성에서는 대퇴골경부 골밀도와 음의 상관관계를 보였다. 결론적으로 TLM은 50세 이상 남성 및 폐경후여성에서 골밀도를 유지하는데 매우 중요한 인자임을 확인할 수 있었다.

• 대한영양사협회학술지
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• 제22권2호
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• pp.106-117
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• 2016

Osteoporosis is a major health problem that can lead to mortality. This study was conducted to estimate the prevalence of osteopenia and osteoporosis separately and to assess the risk factors associated with osteopenia/osteoporosis in Korean men aged 50 years and over. A total of 1,136 subjects were analyzed among the participants of the Korea National Health and Nutrition Examination Survey (KNHANES) 2010~2011 by using SPSS statistics complex samples (windows ver. 23.0). The prevalence rates of osteopenia and osteoporosis were 46.3% and 7.3%, respectively, and the mean ages of both osteopenia and osteoporosis risk groups were significantly higher than that of the normal group. The mean values for lifetime tallest height and bone mineral density in whole body, total femur, femoral neck, and lumbar spine were significantly lower in the risk group(osteopenia/osteoporosis) than in the normal group, whereas the mean values for height, body weight, BMI, waist circumference, alkaline phosphatase, parathyroid hormone, fasting blood glucose, total cholesterol, HDL-cholesterol, LDL-cholesterol, and triglycerides of the two groups showed no significant differences. The intakes of energy and carbohydrates were significantly higher in the risk group than in the normal group. The results of multiple logistic regression showed that being underweight and having hypercholesterolemia were significantly related with the prevalence of osteopenia/osteoporosis, whereas health habits such as smoking and exercise, chronic diseases such as obesity and hypertension, and nutrient intakes were not. These findings suggest the need for further studies to examine osteopenia/osteoporosis risk factors and outcomes specificly focused on Korean men.

• 대한골관절종양학회지
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• 제19권2호
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• pp.78-82
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• 2013

랑게르한스 세포 조직구증(Langerhans' cell histiocytosis)은 단핵구계에 속하는 정상 조직구들이 과도하게 증식하여 다양한 임상 경과와 치료결과를 보이는 질환 군으로 알려져 있다. 특히, 척추에 침범하는 경우에는 단발 혹은 다발성의 골 용해를 특징으로 한다. 병변의 침범 부위, 진행 정도 및 동반 증상에 따라 단순 경과 관찰에서부터 방사선 치료, 화학요법 및 수술적 치료에 이르기까지 다양한 치료법들이 적용되어 왔으나, 아직까지 확립된 치료법은 없는 것으로 알려져 있다. 저자들은 경추와 요추를 동시에 침범하면서 척추 내 골수 파괴 소견과 병적 골절을 동반한 단일조직 랑게르한스 세포 조직구증 환자에 대해 수술적 치료 및 전신화학요법을 시행한 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• The Korean Journal of Pain
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• 제22권3호
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• pp.199-205
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• 2009

Background: A major ingredient of green tea is epigallocatechin-3-gallate (EGCG), and this is known to have many beneficial effects for cancer prevention and also on the cardiovascular system and neurodegenerative diseases through its anti-oxidant, anti-angiogenic, anti-inflammatory, lipid-lowering and neuroprotective properties. Its actions on nociception and the spinal nervous system have been examined in only a few studies, and in these studies EGCG showed an antinociceptive effect on inflammatory and neuropathic pain, and a neuroprotective effect in motor neuron disease. This study was performed to investigate the effect of EGCG on acute thermal pain and the development of morphine tolerance at the spinal level. Methods: The experimental subjects were male Sprague-Dawley rats and the Hot-Box test was employed. A single or double-lumen intrathecal catheter was implanted at the lumbar enlargement for drug administration. An osmotic pump was used to infuse morphine for 7 days for induction of morphine tolerance. EGCG was injected repeatedly for 7 days at twice a day through the intrathecal catheter. Results: Intrathecal EGCG increased the paw withdrawal latency (PWL) after repeated administration for 7 days at twice a day, but this did not happen with administering on single bolus injection of EGCG. In addition, the antinociceptive effect of intrathecal morphine was not affected by co-administration with EGCG. A continuous 7-day infusion of morphine caused a significant decrease of the PWL in the control group (M + S, morphine plus saline). In contrast, intrathecal EGCG injection over 7 days blocked the decrease of the PWL in the experiment group (M + E, morphine plus EGCG). Conclusions: Intrathecal ECGC produced a weak antinociceptive effect for acute thermal pain, but it did not change the morphine's analgesic effect. However, the development of antinociceptive tolerance to morphine was attenuated by administering intrathecal EGCG.

• 한국임상수의학회지
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• 제34권6호
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• pp.420-424
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• 2017

Cystic endometrial hyperplasia (CEH) and uterine dilation (hydro-, muco-, hemato- and pyometra) are common uterine diseases in intact female dogs. The aim of the present study was to assess the usefulness of digital abdominal radiography in diagnosing uterine disease in intact female dogs. Two hundred and thirteen intact female dogs were included, and were classified into four groups on the basis of radiographic uterine visibility (visible/invisible) and ultrasonographic findings (normal uterus/abnormal uterine condition including CEH and uterine dilation). For each dog, the ratio of the maximum uterine diameter to the height of the fifth lumbar vertebral body (U/L5 ratio) was calculated on radiographs. There were 78 and 135 dogs in the normal and abnormal groups, respectively; 34.6% normal and 53.5% abnormal uteri were visible on abdominal radiographs. Our results suggested that a mean U/L5 ratio of $1.18{\pm}0.53$ ($mean{\pm}2SD$) indicated a normal radiographic uterus diameter, and that a value of > 1.60 should be used as an indicator of uterine disease in clinical practice. However, because false negative results were noted, radiography cannot replace ultrasonography for assessment of the uterus.

• 대한정형도수물리치료학회지
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• 제6권2호
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• pp.15-29
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• 2000

Low back pain is generally defined as a complex symptom rather than a specific diseases entity, especially when musculoskeletal lesions of the low back, neurogenic, vasculogenic and discogenic lesions are present. Sixty to eighty percent of all human being have experienced low back pain once or more times during in their lifetime. Low back pain is a one of the commonest cause of physical impairment and induces disability the activities of everyday living or the activities of work. Today, low back pain plays important part for the loss of working capability from social, industrial field and individual daily life. But there are no study about incidence and prevention program of low back pain in rural peoples. This study was conducted to find out current status and characteristics related to low back pain in rural peoples(especially engaged in agriculture), so that could provide basic data to establish prevention program for them. The data were gathered from 301 rural adults(female 62.1%, male 37.9%) with low back pain by the structured interview in the 4 communities(south and north Gyeong-sang Do and Chung-cheong Do), and sampled at local hospital, local clinic, and health clinic center in May, 2000. The results were as followed. About one third of cases(35.5%) were aged from 60 to 69, 34.6% were smoker, and 91.4% not used to regular exercise. Low back pain frequently due to intervertebral articulopathy(42.5%), follewed by herniated intervertebral disk(19.9%), sprain(17.3%), vertebral dislocation(4.0%), and etc(16.2%). Above half of cases(56.5%) were a eight-hour workday, and 61.8% complained of low back pain during work. Mostly, period of agricultural experience was more than 20 years, and cultivated more than 2 crops. Low back pain is common to rural adults, therefore adequate resting time from work and lumbar strengthening exercise program needed to prevent low back pain in rural peoples.

• Pediatric Infection and Vaccine
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• 제8권1호
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• pp.107-113
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• 2001

저자들은 발열과 복통을 주소로 입원한 환아에서 연속적으로 요통 및 둔부 동통을 보여 실시한 자기 공명촬영상 요추 부위의 척추 경막외 농양을 진단하고 수술하였기에 문헌 고찰과 함께 보고하는 바이다.

• 대한수의학회지
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• 제39권4호
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• pp.715-723
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• 1999

Bee venom (BV) has been traditionally applied to relieve pain and to cure inflammatory diseases such as rheumatoid arthritis (RA) and neuritis. While several investigators have evaluated the anti-inflammatory effect of BV treatment, the anti-nociceptive effect of BV treatment on inflammatory pain is not reported. Therefore, we decided to evaluate the analgesic effect of BV treatment using Freund's adjuvant induced chronic arthritis model. Freund's adjuvant-induced arthritis has been used as an experimental animal model for RA in humans to assess the efficacy of the anti-inflammatory/analgesic drugs. In this study, subcutaneous BV treatment (1mg/kg/day) produced significantly reductions of symptoms related to arthritic pain (i.e. mechanical hyperalgesia and thermal hyperalgesia). The anti-nociceptive effect of BV was observed from at least 12 days after BV treatment. Furthermore, BV treatment significantly suppressed adjuvant induced Fos expression in lumbar spinal cord. We also found that local injection of BV into near the inflammatory site (especially Zusanli-acupoint) showed more potent analgesic effect on arthritic pain rather than distant injection of BV from inflammatory site (arbitrary side of back). The present study demonstrates that BV treatment has anti-nociceptive effect on arthritis induced inflammatory pain. The analgesic effect of BV on RA is probably mediated by the effect of BV itself or possible other mechanism such as counter-irritation. Furthermore, it is possible that BV acupuncture is one of the promising candidates for long-term therapy of RA.