• 제목/요약/키워드: long-term observation

검색결과 526건 처리시간 0.024초

Long-term Outcomes of Patients With Early Gastric Cancer Who Had Lateral Resection Margin-Positive Tumors Based on Pathology Following Endoscopic Submucosal Dissection

  • Jun Hee Lee;Sang Gyun Kim;Soo-Jeong Cho
    • Journal of Gastric Cancer
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    • 제24권2호
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    • pp.199-209
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    • 2024
  • Purpose: Long-term outcomes of patients with positive lateral margins (pLMs) after endoscopic submucosal dissection (ESD) for early gastric cancer (EGC). This study aimed to evaluate the remnant cancer and survival rates of patients with pLMs compared with those who underwent curative resection. Materials and Methods: A retrospective analysis was performed on consecutive patients with pLMs as the only non-curative factor of expanded indication who underwent ESD for EGC with a follow-up duration of 5 years or more. The rates of remnant cancer, recurrence, and survival were analyzed and compared to those of control patients who underwent curative resection by propensity score matching. Results: Among 3,515 patients treated with ESD between 2005 and 2018, 123 non-curative EGCs were retrospectively analyzed. A total of 108 patients were followed up without endoscopic or surgical resection for 8.2 years. The control group was matched in a 1:1 ratio with patients with EGC who underwent curative resection after ESD. The observation group with pLMs had a higher incidence of remnant cancer (25.9%; 28/108) compared to that in the curative resection group (0/108; P=0.000). The remaining tumors were treated with surgical or endoscopic resection, and no additional recurrences were observed. The overall survival analysis demonstrated no significant difference between the observation and curative resection groups (P=0.577). Conclusions: No difference was observed in the overall survival rate between observation and curative resection groups. Therefore, observation may be a possible option for incomplete ESD with pLMs if continuous follow-up is performed.

Effects of acupuncture in postmenopausal women with prehypertension or stage 1 hypertension: study protocol for a prospective, comparative, interventional cohort study

  • Seo, Bok-Nam;Park, Ji-Eun;Kim, Young-Eun;Kang, Kyung-Won;Seol, In-Chan;Choi, Sun-Mi
    • Integrative Medicine Research
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    • 제7권1호
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    • pp.95-102
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    • 2018
  • Background: Hypertension is a major cause of cardiovascular disease and associated mortality, and postmenopausal women are at a high risk of hypertension. We aim to investigate the hypotensive effect and safety of acupuncture, focusing on postmenopausal women with prehypertension and stage 1 hypertension. In addition, we aim to investigate whether the effect of acupuncture treatment differed, depending on Sasang Constitution and cold-heat pattern. Methods: This study is designed as an intervention cohort study. Two hundred postmenopausal women aged <65 years with prehypertension or stage 1 hypertension living in Daejeon city in Korea will be recruited, and randomly assigned to either an acupuncture or no-treatment control group. The intervention will consist of four sessions; one session will include acupuncture performed 10 times for 4 weeks. There will be a 20-week observation period after each session, and the total study duration will be 96 weeks. Acupuncture will be applied at the bilateral Fengchi (GB20), Quchi (LI11), Zusanli (ST36), and Sameumgyo (SP6) acupoints. The effect of acupuncture will be evaluated by comparing the change in systolic and diastolic blood pressure between the acupuncture and control groups every 4 weeks until the end of the study. Discussion: To evaluate the success of blood pressure management, long-term observation is required, but no long-term studies have been conducted to evaluate the effect of acupuncture on blood pressure in postmenopausal women. To our knowledge, this study will be the first long-term study to investigate this issue for more than 6-8 weeks.

회귀모형에 의한 서해안 평균해면의 연시계열자료의 평가 (The Evaluation of the Annual Time Series Data for the Mean Sea Level of the West Coast by Regression Model)

  • 조기태;박영기;이장춘
    • 한국환경과학회지
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    • 제9권1호
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    • pp.19-25
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    • 2000
  • As the tideland reclamation is done on a large scale these days, construction work is active in the coastal areas. Facilities in the coastal areas must be built with the tide characteristics taken into consideration. Thus the tide characteristics affect the overall reclamation plan. The analysis of the tide data boils down to a harmonic analysis of the hourly changes of long-term tide data and extraction of unharmonic coefficients from the results. Since considerable amount of tide data of the West Coast are available, the existing data can be collected and can be used to obtain the temporal changes of the tide by being fitted into the tide prediction model. The goal of this thesis lies in assessing whether the mean sea level used in the field agrees with the analysis results from the long-term observation data obtained with their homogeneity guaranteed. To achieve this goal, the research was conducted as follows. First the present conditions of the observation stations, the land level standard, and the sea level standard were analyzed to set up a time series model formula for representing them. To secure the homogeneity of the time series, each component was separated. Lastly the mean sea level used in the field was assessed based on the results obtained form the analysis of the time series.

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미소지진(微小地震) 장기관측(長期觀測)을 위한 지진기록계(地震記錄計)의 개발(開發) (Development of Seismic Recorder for Long-term Observation of Microearthquakes)

  • 김성균;조규장;정부흥;문창배;신인철;성낙훈
    • 자원환경지질
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    • 제21권2호
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    • pp.185-191
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    • 1988
  • A two channel seismic recorder suitable for long-term observation of microearthquakes is developed. The direct analogue recording on cassette tape is adopted in the recorder whose circuits of amplifier and mortor units of an audio cassette recorder are modified. The recorder provides contineous record of 10 days with DC 12V battery (100AH) and with standard cassette tape of 60 minute use. The binary coded time signals of date, hour, and minute are generated once a minute by the timing system and absolute time input using radio to measure the time drift is also possible. For the seismic signal processing, the analogue signals from audio cassette player pass A/D converter and digitized data are stored in personal computer. Then visual records can be obtained using computer graphic mode. Basic programs "ADCONVO" and "DRAWO" to accomplish A/D conversions, the creation of data files and visualization of signals were written. Some sample signals reproduced from the recorded tape are presented.

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인공위성 관측 자료를 이용한 해양-대기 DMS flux 추정 및 장기 추세 분석 (Estimations and Long-term Trend of Sea-to-air Dimethyl Sulfide (DMS) Flux using Satellite Observation Data)

  • 최유나;송상근;한승범;손영백;박연희
    • Ocean and Polar Research
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    • 제39권3호
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    • pp.181-194
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    • 2017
  • The long-term linear trend of global sea-to-air dimethyl sulfide (DMS) flux was analyzed over a 16-year time span (2000~2015), based on satellite observation data. The emission rates of DMS (i.e. DMS flux) in the global ocean were estimated from sea surface DMS concentrations, which were constructed with chlorophyll a (Chl-a) concentrations and mixed layer depths (MLD), and transfer velocity from sea to air, which was parameterized with sea surface wind (SSW) and sea surface temperature (SST). In general, the DMS flux in the global ocean exhibited a gradual decreasing pattern from 2000 (a total of 12.1 Tg/yr) to 2015 (10.7 Tg/yr). For the latitude band ($10^{\circ}$ interval between $0^{\circ}$ and $60^{\circ}$), the DMS flux at the low latitude of the Northern (NH) and Southern hemisphere (SH) was significantly higher than that at the middle latitude. The seasonal mean DMS flux was highest in winter followed by in summer in both hemispheres. From the long-term analysis with the Mann-Kendall (MK) statistical test, a clear downward trend of DMS flux was predicted to be broad over the global ocean during the study period (NH: $-0.001{\sim}-0.036{\mu}mol/m^2/day\;per\;year$, SH: $-0.011{\sim}-0.051{\mu}mol/m^2/day\;per\;year$). These trend values were statistically significant (p < 0.05) for most of the latitude bands. The magnitude of the downward trend of DMS flux at the low latitude in the NH was somewhat higher than that at the middle latitude during most seasons, and vice versa for the SH. The spatio-temporal characteristics of DMS flux and its long-term trend were likely to be primarily affected not only by the SSW (high positive correlation of r = 0.687) but also in part by the SST (r = 0.685).

ASTRONAUT'S EARTH OBSERVATION ON THE INTERNATIONAL SPACE STSTION

  • Lee Joo-Hee;Kim Yeon-Kyu;Kim Jong-Woo;Choi Gi-Hyuk
    • 대한원격탐사학회:학술대회논문집
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    • 대한원격탐사학회 2005년도 Proceedings of ISRS 2005
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    • pp.624-627
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    • 2005
  • Ministry of Science & Technology (MOST) and Korea Aerospace Research Institute (KARI) are preparing for the first Korean astronaut program based on the mid and long-term basic plan for space development of Korea from the year of 2003. KARI is making plans for the Korean astronaut's missions with Russia. To participate in the International Space Station (ISS) utilization through the Korean astronaut program, KARI investigates a lot of manned space missions. Among the suggested items, Earth observation on the Russian Module of ISS is the one expected mission for a Korean astronaut. This paper is intended to give readers a brief introduction of ISS Russian Module and research fields of Earth observation for astronaut's mission.

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CAT을 이용한 저수지 수위 예측 (Prediction of Reservoir Water Level using CAT)

  • 장철희;김현준;김진택
    • 한국농공학회논문집
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    • 제54권1호
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    • pp.27-38
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    • 2012
  • This study is to analyse the hydrological behavior of agricultural reservoir using CAT (Catchment hydrologic cycle Assessment Tool). The CAT is a water cycle analysis model in order to quantitatively assess the characteristics of the short/long-term changes in watershed. It supports the effective design of water cycle improvement facilities by supplementing the strengths and weaknesses of existing conceptual parameter-based lumped hydrologic models and physical parameter-based distributed hydrologic models. The CAT especially supports the analysis of runoff processes in paddy fields and reservoirs. To evaluate the impact of agricultural reservoir operation and irrigation water supply on long-term rainfall-runoff process, the CAT was applied to Idong experimental catchment, operated for research on the rural catchment characteristics and accumulated long term data by hydrological observation equipments since 2000. From the results of the main control points, Idong, Yongdeok and Misan reservoirs, the daily water levels of those points are consistent well with observed water levels, and the Nash-Sutcliffe model efficiencies were 0.32~0.89 (2001~2007) and correlation coefficients were 0.73~0.98.

국내 연안 카페리 차량 고박 장치 안전성에 관한 연구: 제I부 직접하중계산법을 이용한 선체 운동 가속도 산정 (Study on Structural Safety of Car Securing Equipment for Coastal Carferry: Part I Estimation of Hull Acceleration using Direct Load Approach)

  • 정준모;조희상;이경훈;이영우
    • 한국해양공학회지
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    • 제30권6호
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    • pp.440-450
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    • 2016
  • The capsizing and consequent sinking of a coastal car ferry was recently reported, with numerous human casualties. The primary cause was determined to be a sudden turn with improperly stowed and secured cargo. Part I of this study introduces how long term acceleration components are determined from seakeeping analyses. A carferry with a displacement of 1,633 tonf was selected as the target vessel. Sea data that included the significant wave heights and periods were collected at four observation buoys, some of which were far away from two main voyage routes: Incheon-Jeju and Pusan-Jeju. Frequency response analyses were performed to obtain the linearized radiation force coefficients, hydrostatic stiffnesses, and wave excitation forces. Time response analyses were sequentially performed to produce the motion-induced acceleration processes. The probabilistic distributions of the acceleration components were determined using a peak and valley counting method. Long term extreme acceleration components were proposed as a final result.

Prediction of Long-term Solar Activity based on Fractal Dimension Method

  • Kim, Rok-Soon
    • 천문학회보
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    • 제41권1호
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    • pp.45.3-46
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    • 2016
  • Solar activity shows a self-similarity as it has many periods of activity cycle in the time series of long-term observation, such as 13.5, 51, 150, 300 days, and 11, 88 years and so on. Since fractal dimension is a quantitative parameter for this kind of an irregular time series, we applied this method to long-term observations including sunspot number, total solar irradiance, and 3.75 GHz solar radio flux to predict the start and maximum times as well as expected maximum sunspot number for the next solar cycle. As a result, we found that the radio flux data tend to have lower fractal dimensions than the sunspot number data, which means that the radio emission from the sun is more regular than the solar activity expressed by sunspot number. Based on the relation between radio flux of 3.75 GHz and sunspot number, we could calculate the expected maximum sunspot number of solar cycle 24 as 156, while the observed value is 146. For the maximum time, estimated mean values from 7 different observations are January 2013 and this is quite different to observed value of February 2014. We speculate this is from extraordinary extended properties of solar cycle 24. As the cycle length of solar cycle 24, 10.1 to 12.8 years are expected, and the mean value is 11.0. This implies that the next solar cycle will be started at December 2019.

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장기유출모의를 위한 수문시계열 예측모형의 적용성 평가 (Application to Evaluation of Hydrologic Time Series Forecasting for Long-Term Runoff Simulation)

  • 윤선권;안재현;김종석;문영일
    • 한국수자원학회논문집
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    • 제42권10호
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    • pp.809-824
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    • 2009
  • 한정된 기간의 짧은 유출량 기록을 갖는 댐 유역에서의 수자원 시스템 거동예측은 수문학적 지속성여부에 대한 판단이 선행 되어야 하며 가용한 시계열자료에 대한 추계학적 분석을 통하여 실시하여야 한다. 본 연구에서는 계절형 ARIMA모형을 통하여 안동댐 유역의 강우량, 증발량 및 유출량 시계열자료로 월별 수문시스템 거동을 예측하였으며, 예측된 결과를 토대로 TANK모형과 ARIMA+TANK결합모형에 의한 장기유출모의를 실시하였다. 분석결과 관측자료의 특성을 비교적 잘 반영 하였으며, 댐 유입량 예측을 위한 추계학적 결합모형의 적용가능성을 검토하였다. 이는 상대적으로 유출량자료의 보유년한이 짧은 대상유역의 시계열 수문인자 예측을 통한 유출모의의 적용으로 수자원의 중 장기 전략수립에 도움이 되리라 사료된다.