• Korean journal of applied entomology
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• v.47 no.4
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• pp.407-411
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• 2008

This study was conducted to estimate the economic injury level (EIL) and economic threshold (ET) of the green peach aphid, Myzus persicae, on Chinese cabbage (Brassica campestris var). The changes of biomass of Chinese cabbage and M. persicae density were investigated after introduction of M. persicae at different density (0, 2, 5, 10, 15, and 20 per plant; inoculated at 10d after planting). The densities of M. persicae largely increased from the above initial densities to 0, 92.3, 177.4, 406.9, 440.4, and 471.3 aphids per plant at 18d after the initial inoculation, respectively. The biomass of Chinese cabbage significantly decreased with increasing the initial inoculated density of M. persicae: 602.0, 264.2, 262.0, 109.3, 151.0, and 67.3 g in above plots with different initial densities, respectively. The relationship between cumulative aphid days (CAD) and yield loss (%) of Chinese cabbage was well described by a nonlinear logistic equation. Using the estimated equation, EIL of M. persicae on Chinese cabbage was estimated 25 CAD per plant based on the yield loss 13%, which take into account of an empirical gain threshold 5% and marketable rate 92% of spring Chinese cabbage. Also, ET was calculated at 80% of EIL: 20 aphids per plant. Until a more elaborate EIL-model is developed, the present result may be useful for M. persicae management at early growth stage of Chinese cabbage.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.11
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• pp.4637-4642
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• 2014

Background: Hypoxia-inducible factor $1{\alpha}$ (HIF-$1{\alpha}$) plays an important role in regulating cell survival and angiogenesis, which are critical for tumor growth and metastasis. Genetic variations of HIF1A have been shown to influence the susceptibility to many kinds of human tumors. Increased expression of HIF-$1{\alpha}$ has also been demonstrated to be involved in tumor progression. However, the prognostic value of single nucleotide polymorphisms (SNPs) inthe HIF1A gene remains to be determined in most cancer types, including colorectal cancer (CRC). In this study, we sought to investigate the predictive role of HIF1A SNPs in prognosis of CRC patients and efficacy of chemotherapy. Materials and Methods: We genotyped two functional SNPs in HIF1A gene using the Sequenom iPLEX genotyping system and then assessed their associations with clinicopathological parameters and clinical outcomes of 697 CRC patients receiving radical surgery using Cox logistic regression model and Kaplan Meier curves. Results: Generally, no significant association was found between these 2 SNPs and clinical outcomes of CRC. In stratified analysis of subgroup without adjuvant chemotherapy, patients carrying CT/TT genotypes of rs2057482 exhibited a borderline significant association with better overall survival when compared with those carrying CC genotype [Hazard ratio (HR), 0.47; 95% confidence interval (95% CI): 0.29-0.76; P < 0.01]. Moreover, significant protective effects on CRC outcomes conferred by adjuvant chemotherapy were exclusively observed in patients carrying CC genotype of rs2057482 and in those carrying AC/CC genotype of rs2301113. Conclusions: Genetic variations in HIF1A gene may modulate the efficacy of adjuvant chemotherapy after surgery in CRC patients.

• Sleep Medicine and Psychophysiology
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• v.21 no.2
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• pp.61-68
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• 2014

Objective: The aim of the present study is to assess the prevalence and related risk factors of suicide ideation among middle and high school students in an urban area. Methods: We surveyed 3,691 middle and high school students (2,159 male, 1,532 female, 11-19 years of age) using a self-report questionnaire that covered basic socio-demographic data, academic achievements, presence of physical or psychiatric illness, sleep duration on weekdays, time spent at private academies on weekdays and weekends, and subjective needs for counseling. The Beck Depression Inventory (BDI) and Reynolds' Suicidal Ideation Questionnaire (SIQ) were included in the survey. Results: The prevalence of students with high suicide ideation ($SIQ{\geq}62$) was 4.6%. In a logistic regression model, female sex (p = 0.002), younger age (p < 0.001), poor academic achievement (p = 0.043) and higher score of BDI (p < 0.001) were associated with a higher SIQ score. In addition, younger age (p = 0.045) and a higher BDI score (p < 0.001) were associated with a higher SIQ score adolescents having high suicide ideation ($SIQ{\geq}62$). Conclusion: Related risk factors of suicide ideation in adolescents were female sex, younger age, poor academic achievement, and a depressive mood. It would be especially helpful to pay more attention to younger adolescents and a depressive mood as a high-risk group. The understanding of these factors will be helpful for providing an effective suicide screening and prevention program for adolescents.

• Journal of Environmental Health Sciences
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• v.41 no.5
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• pp.335-348
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• 2015

Objectives: We aimed to assess the risk of metabolic syndrome one year after the 2007 Hebei Spirit oil spill in Taean, Korea among people exposed to spilt oil during clean-up work. Methods: A total of 6,923 adults, including 3,019 males and 3,904 females, participated in the study. Health examinations and blood tests (total cholesterol, triglycerides, HDL, fasting blood sugar) were performed. A logistic regression model adjusting for age, gender, smoking history, drinking history, income, education, and marital status was used to estimate the risk of metabolic syndrome associated with the level of oil spill exposure. Results: The prevalence of metabolic syndrome was 24.9% among males and 18% among females. Compared with people living within 20 km of the coastline, the risk of metabolic syndrome among people living within 0.8 km of the coastline was significantly higher (male OR=1.696, 95% CI=1.320-2.178, female OR=1.992, 95% CI=1.549-2.561), including a significant dose-response relationship for distance from early contaminate coastline (p<0.001). The risk of metabolic syndrome was higher according to the increase of duration of cleaning work. The risk of metabolic syndrome among people who participated in the clean-up work for more than 116 days, compared with people who participated in the cleaning work for or less 14 days, was significantly higher (male OR=1.845, 95% CI=1.448-2.353, female OR=1.752, CI=1.378-2.228), with a significant dose-response relationship for days of clean-up work (p<0.001). Conclusion: This study showed that there is a significant association between exposure to the oil spill during the clean-up work, distance from early contaminate coastline and the risk of metabolic syndrome in a doseresponse manner.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.25 no.3
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• pp.405-417
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• 2015

Objectives: The aim of this study is to evaluate the association between physical factors, working conditions and occupational injuries among Korean workers. Methods: We used data from the 2nd Korean Working Conditions Survey, conducted in 2010. A total of 7,114 workers over 15 years of age were selected from among 10,019 Korean workers. The participants were interviewed using questionnaires. A multiple logistic regression model was used to analyze the associations among physical factors, working conditions and occupational injuries. Results: After the adjustment of socio-demographic factors, the odds ratio of injuries through physical factors such as vibration (adjusted Odds Ratio [aOR] 4.037, 95% CI 2.30-7.09), noise (aOR 4.562, 95% CI 2.64-7.89), high temperature (aOR 3.262, 95% CI 1.86-5.73), and low temperature (aOR 3.358, 95% CI 1.76-6.41) were greater in the exposed group than in the non-exposed group. The odds ratios of occupational injury(aOR 5.272, 95% CI 3.19-8.7 for very high speed work, aOR 3.303, 95% CI 1.95-5.60 for tight deadlines, and aOR 3.641, 95% CI 1.72-7.70 for not enough time to work) increased with increased work demands. Conclusions: In this study, physical factors such as vibration, noise, and high and low temperatures were significantly correlated with occupational injuries according to the increase in exposure intensity(p for trend <0.001). Also, working conditions such as high-speed work, tight deadlines and insufficient time to work showed significant associations with occupational injuries(p for trend<0.001).

• Journal of Gastric Cancer
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• v.13 no.4
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• pp.214-225
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• 2013

Purpose: Peritoneal lavage cytology is part of the routine staging workup for patients with advanced gastric cancer. However, no quality assurance study has been conducted to show variations or biases in peritoneal lavage cytology results. The aim of this study was to demonstrate a test execution variation in peritoneal lavage cytology between investigating surgeons. Materials and Methods: A prospective cohort study was designed for determination of the positive rate of peritoneal lavage cytology using a liquid-based preparation method in patients with potentially curable advanced gastric cancer (cT2~4/N0~2/M0). One hundred thirty patients were enrolled and underwent laparotomy, peritoneal lavage cytology, and standard gastrectomy, which were performed by 3 investigating surgeons. Data were analyzed using the chi-square test and a logistic regression model. Results: The overall positive peritoneal cytology rate was 10.0%. Subgroup positive rates were 5.3% in pT1 cancer, 2.0% in pT2/3 cancer, 11.1% in pT4a cancer, and 71.4% in pT4b cancer. In univariate analysis, positive peritoneal cytology showed significant correlation with pT stage, lymphatic invasion, vascular invasion, ascites, and the investigating surgeon. We found the positive rate to be 2.1% for surgeon A, 10.2% for surgeon B, and 20.6% for surgeon C (P=0.024). Multivariate analysis identified pT stage, ascites, and the investigating surgeon to be significant risk factors for positive peritoneal cytology. Conclusions: The peritoneal lavage cytology results were significantly affected by the investigating surgeon, providing strong evidence of test execution variation that could be related to poor diagnostic accuracy and stage migration in patients with advanced gastric cancer.

• Genomics & Informatics
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• v.8 no.4
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• pp.206-211
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• 2010

The Fas (TNF receptor superfamily, member 6) (FAS)/FAS ligand (FASLG) interaction plays a central role in the regulation of programmed cell death. FAS and FASLG polymorphisms in promoter regions affect transcriptional activities. To investigate whether FAS and FASLG polymorphisms are associated with the development and clinical phenotypes of stroke, 2 promoter single nucleotide polymorphisms (SNPs) in FAS (rs1800682, -670C/T) and FASLG (rs763110, -844C/T) were selected and genotyped by direct sequencing in 220 stroke patients [107 ischemic stroke (IS), 77 intracerebral hemorrhage (ICH), and 36 subarachnoid hemorrhage (SAH)] and 369 control subjects. For the analysis of clinical symptoms, all stroke patients were divided into 3 clinical phenotypes according to the respective results of the National Institutes of Health Stroke Survey (NIHSS) and the Modified Barthel Index (MBI) and the presence or absence of complex regional pain syndrome (CRPS). The SNPStats, SNPAnalyzer, and Helixtree programs were used to analyze the genetic data. Multiple logistic regression models (codominant, dominant, and recessive) were used to estimate odds ratios (ORs), 95% confidence intervals (CIs), and p-values. The promoter SNP rs1800682 was associated with stroke in the codominant (OR=0.48, 95% CI=0.25-0.94, p=0.04) and dominant models (OR=0.51, 95% CI=0.30-0.87, p=0.011). However, a FASLG SNP (rs763110) was not in Hardy-Weinberg equilibrium (p<0.05). In the analysis of stroke types, rs1800682 was associated with IS in the codominant (OR=0.30, 95% CI=0.12-0.74, p=0.025), dominant (OR=0.44, 95% CI=0.23-0.88, p=0.018), and recessive models (OR=0.45, 95% CI=0.21-0.99, p=0.042). The genotype frequencies of rs1800682 were different between ICH and controls in the dominant model (OR=0.49, 95% CI=0.26-0.94, p=0.031) but not between SAH and controls. In the analysis of clinical symptoms, however, rs1800682 was not related to the 3 clinical phenotypes (NIHSS, MBI, and CRPS). These results suggest that a promoter SNP (rs1800682, -670C/T) in FAS may be associated with the development of stroke in the Korean population.

• Korean Journal of Social Welfare
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• v.64 no.2
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• pp.273-298
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• 2012

This study is targeted to understand the giving of time and money among citizens in Seoul. It explores predictors of different combinations of giving behaviors: only volunteering, only donating, doing both, and neither. In exploring predictors, it also considers the effects of intensity in giving with differential measurement of general participation and regular participation. For the analysis, this study utilizes Seoul Welfare Panel Survey Data in 2008 and 2010 and employes a multi-nominal logistic regression model with selection of citizens' demographic factors, pro-social attitude factors, and psycho-social factors on these four type of giving behaviors. The findings show that previous giving experiences(+) and religious activities(+) have statistically significant effects on both selective and combined giving behavior. Gender(woman), income(+), education(+) have statistically significant effects on giving behaviors(only donating and doing both) related with donation. In the case of employment state, unemployment is significantly related to volunteering while employment is significantly related to donating. Finally, happiness(+) has significantly positive effect on intensive giving such as regular giving rather than general giving. This analysis has made a start in a new area of inquiry attempting to explain different giving behaviors with broadening and promoting understanding on giving behaviors. Moreover, it raises several implications for future research and strategic practice for resource mobilization of NPOs.

• Korean Journal of Health Education and Promotion
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• v.12 no.2
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• pp.48-61
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• 1995

This study attempted to analyze the health habits affecting health status of industrial workers. Data was collected from 57 industries of 900 workers at Inchon. The research has been carried out through self-administered questionnaire and from the analysis of the health examination records and the results were as follows: 1. Among 861 respondents, men were 81.2%, women were 18.8%, 42, 6% were of the 30-40 age group, the married were 65.7%, the single were 32.5%, the high school graduates were 62.4% and 37.3% were of people who worked between 1 and 5 years. 2. As far as the seven health habits, current smokers were 54.9%, people who regularly exercise was 31.7%, 7-8 hour of sleep, on the average were 74.0%, people eating breakfast nearly every day were 8.0%, and people eating between meals almost every day were 54.2%. Heavy drinkers who drink 3-4 times or more per week were 13.2%, 1-2 times per week were 26.8% and the obese were 4.6%, 3. Health status of A and B, estimated by doctors in the health examination were 81.7% and C, D1, D2, the unhealthy were 18.3%. Men were reported more than women in unhealthy groups and the results regarding health status reflect gender, educational level and age, That is to say that, lower educational level group and over 30 years of age group perceive their health to be worse than the higher educational level and under 30 age group, And these differences were statistically significant. 4. The relationship between health habits and health status, expressed in terms of the odds ratio. Current smokers had a consistently worse health status than a nonsmokers with a 1.36 odds ratio. The workers who reported eating breakfast rarely or never were more associated with the unhealthy group than the regular breakfast eating group with a 2.48 odds ratio. One or more drink per week had a worse health status than a never or a little drinker with a 1.42 odds ratio. 5, The Health habits score and duration of work were selected as significant factors influencing health status based on logistic analysis. According to the results of this model, the odds ratio of good health status was 2.06 for good health habit score, 1.55 for population who worked seven years or more duration of work. As we have seen, good practices were found to be associated with better health and the effect of the health habits was cummulative;those who followed 6-7 health habits were in better health, even though they were older than those who failed to do so. Therefore, in order to provide the health promotion of workers it is necessary to establish a health management plan for an effective health education and health service. If we use this type of study as a prospective study design, we can get a precise basic data for health promotion and a management plan for industrial workers.

• Science of Emotion and Sensibility
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• v.23 no.2
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• pp.13-22
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• 2020

This study aimed to investigate the association between asthma and emotions, such as depression, stress, and health awareness. We observed the effects of blood indices on asthma in Korean adults. Data from 5852 adults were taken from the 2017 Seventh Korea National Health and Nutrition Examination Survey and analyzed using a multivariate logistic regression model. The probability of asthma occurrence in over 65 years old was higher than in 19-44 years old (OR = 1.48), and asthma occurrence was high in subjects with low educational (OR = 1.89) and income (OR = 2.07) levels. With regard to marital status, singleness and divorce and dye were found to have increased the probability of asthma occurrence by 1.62- and 2.30-folds, respectively. The restriction of activities was another factor that increased with asthma occurrence (OR = 2.39). In terms of emotions, general health awareness was significantly 3.45 times increased the probability of asthma occurrence at their health bad awareness. Furthermore, depression (OR = 1.782) was shown to have increased asthma occurrence. The blood index of C-CRP 1.12 times increased the probability of asthma occurrence. The factors that influenced asthma occurrence were age, education, income, marital status, the restriction of activities, general health awareness, depression, and C-CRP. Emotional factors and blood indices are potential risk factors for the development of asthma in Korean adults. By understanding the increased risks of asthma occurrence with general characteristics and emotional factors and blood indices, the management and prevention of asthma should include the management of emotional factors.