• 제목/요약/키워드: locally weighted regression

검색결과 27건 처리시간 0.023초

Epidemiological application of the cycle threshold value of RT-PCR for estimating infection period in cases of SARS-CoV-2

  • Soonjong Bae;Jong-Myon Bae
    • Journal of Medicine and Life Science
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    • 제20권3호
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    • pp.107-114
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    • 2023
  • Epidemiological control of coronavirus disease 2019 (COVID-19) is needed to estimate the infection period of confirmed cases and identify potential cases. The present study, targeting confirmed cases for which the time of COVID-19 symptom onset was disclosed, aimed to investigate the relationship between intervals (day) from symptom onset to testing the cycle threshold (CT) values of real-time reverse transcription-polymerase chain reaction. Of the COVID-19 confirmed cases, those for which the date of suspected symptom onset in the epidemiological investigation was specifically disclosed were included in this study. Interval was defined as the number of days from symptom onset (as disclosed by the patient) to specimen collection for testing. A locally weighted regression smoothing (LOWESS) curve was applied, with intervals as explanatory variables and CT values (CTR for RdRp gene and CTE for E gene) as outcome variables. After finding its non-linear relationship, a polynomial regression model was applied to estimate the 95% confidence interval values of CTR and CTE by interval. The application of LOWESS in 331 patients identified a U-shaped curve relationship between the CTR and CTE values according to the number of interval days, and both CTR and CTE satisfied the quadratic model for interval days. Active application of these results to epidemiological investigations would minimize the chance of failing to identify individuals who are in contact with COVID-19 confirmed cases, thereby reducing the potential transmission of the virus to local communities.

Prediction of concrete compressive strength using non-destructive test results

  • Erdal, Hamit;Erdal, Mursel;Simsek, Osman;Erdal, Halil Ibrahim
    • Computers and Concrete
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    • 제21권4호
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    • pp.407-417
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    • 2018
  • Concrete which is a composite material is one of the most important construction materials. Compressive strength is a commonly used parameter for the assessment of concrete quality. Accurate prediction of concrete compressive strength is an important issue. In this study, we utilized an experimental procedure for the assessment of concrete quality. Firstly, the concrete mix was prepared according to C 20 type concrete, and slump of fresh concrete was about 20 cm. After the placement of fresh concrete to formworks, compaction was achieved using a vibrating screed. After 28 day period, a total of 100 core samples having 75 mm diameter were extracted. On the core samples pulse velocity determination tests and compressive strength tests were performed. Besides, Windsor probe penetration tests and Schmidt hammer tests were also performed. After setting up the data set, twelve artificial intelligence (AI) models compared for predicting the concrete compressive strength. These models can be divided into three categories (i) Functions (i.e., Linear Regression, Simple Linear Regression, Multilayer Perceptron, Support Vector Regression), (ii) Lazy-Learning Algorithms (i.e., IBk Linear NN Search, KStar, Locally Weighted Learning) (iii) Tree-Based Learning Algorithms (i.e., Decision Stump, Model Trees Regression, Random Forest, Random Tree, Reduced Error Pruning Tree). Four evaluation processes, four validation implements (i.e., 10-fold cross validation, 5-fold cross validation, 10% split sample validation & 20% split sample validation) are used to examine the performance of predictive models. This study shows that machine learning regression techniques are promising tools for predicting compressive strength of concrete.

Functional Magnetic Resonance Imaging in the Diagnosis of Locally Recurrent Prostate Cancer: Are All Pulse Sequences Helpful?

  • Liao, Xiao-Li;Wei, Jun-Bao;Li, Yong-Qiang;Zhong, Jian-Hong;Liao, Cheng-Cheng;Wei, Chang-Yuan
    • Korean Journal of Radiology
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    • 제19권6호
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    • pp.1110-1118
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    • 2018
  • Objective: To perform a meta-analysis to quantitatively assess functional magnetic resonance imaging (MRI) in the diagnosis of locally recurrent prostate cancer. Materials and Methods: A comprehensive search of the PubMed, Embase, Cochrane Central Register of Controlled Trials, and Cochrane Database of Systematic Reviews was conducted from January 1, 1995 to December 31, 2016. Diagnostic accuracy was quantitatively pooled for all studies by using hierarchical logistic regression modeling, including bivariate modeling and hierarchical summary receiver operating characteristic (HSROC) curves (AUCs). The Z test was used to determine whether adding functional MRI to T2-weighted imaging (T2WI) results in significantly increased diagnostic sensitivity and specificity. Results: Meta-analysis of 13 studies involving 826 patients who underwent radical prostatectomy showed a pooled sensitivity and specificity of 91%, and the AUC was 0.96. Meta-analysis of 7 studies involving 329 patients who underwent radiotherapy showed a pooled sensitivity of 80% and specificity of 81%, and the AUC was 0.88. Meta-analysis of 11 studies reporting 1669 sextant biopsies from patients who underwent radiotherapy showed a pooled sensitivity of 54% and specificity of 91%, and the AUC was 0.85. Sensitivity after radiotherapy was significantly higher when diffusion-weighted MRI data were combined with T2WI than when only T2WI results were used. This was true when meta-analysis was performed on a per-patient basis (p = 0.027) or per sextant biopsy (p = 0.046). A similar result was found when $^1H$-magnetic resonance spectroscopy ($^1H$-MRS) data were combined with T2WI and sextant biopsy was the unit of analysis (p = 0.036). Conclusion: Functional MRI data may not strengthen the ability of T2WI to detect locally recurrent prostate cancer in patients who have undergone radical prostatectomy. By contrast, diffusion-weight MRI and $^1H$-MRS data may improve the sensitivity of T2WI for patients who have undergone radiotherapy.

지리가중회귀모델을 적용한 빈집 발생의 공간적 특성 분석 - 부산광역시를 대상으로 - (Analysis of Spatial Characteristics of Vacant Houses using Geographic Weighted Regression Model - Focus on Busan Metropolitan City -)

  • 김지윤;김호용
    • 한국지리정보학회지
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    • 제24권1호
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    • pp.68-79
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    • 2021
  • 최근 도시지역의 빈집 발생은 주목할 만한 사회문제이다. 물리적 쇠퇴 현상 중 하나인 빈집 발생은 인구감소, 상권침체 등 다양한 사회·경제적 쇠퇴를 가속화 시킨다. 빈집은 지역적 특성 및 공간적 영향력이 존재하며, 정확한 빈집 실태를 파악하기 위해서는 국지적으로 접근할 필요성이 있다. 이에 본 연구에서는 전역적 Moran's I와 지리가중회귀모델(GWR)을 활용하여 도시쇠퇴가 빈집 발생에 미치는 영향을 지역별로 살펴보았다. 분석 결과, 부산광역시 읍면동별 빈집 발생은 공간적 자기상관성 및 이질성이 존재하였다. 또한 각각의 도시쇠퇴 변수들이 빈집 발생에 미치는 영향이 차이가 있으며, 동일한 도시쇠퇴 변수라도 지역에 따라 빈집 발생에 미치는 영향력이 다르게 나타났다. 이에 GWR모델을 활용하여 지역별로 차별화된 계수 값을 해석하고 빈집 발생을 유형화 한다면 보다 효율적인 빈집 관리 방안을 제시할 수 있을 것으로 보여진다.

강우-유출 모형 적용을 위한 강우 내삽법 비교 및 2단계 일강우 내삽법의 개발 (Comparison of Daily Rainfall Interpolation Techniques and Development of Two Step Technique for Rainfall-Runoff Modeling)

  • 황연상;정영훈;임광섭;허준행
    • 한국수자원학회논문집
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    • 제43권12호
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    • pp.1083-1091
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    • 2010
  • 분포형 수문 모형의 일강우 입력 자료는 불가피하게 불규칙하고 밀도가 낮은 관측망에서 기록된 값을 내삽해 사용하게 되나, 흔히 사용되는 대부분의 내삽법들은 실제 일강우의 다양한 공간적 분포를 잘 재현하지 못하는 문제가 있다. 본 연구에서는 널리 사용되는 다섯 가지의 강우 내삽 방법을 두개의 유역에 사용하여 비교하고 실제 공간적 분포를 보다 잘 나타낼 수 있는 2단계 내삽법을 제안하였다. 비교에 사용된 내삽법은 (1) 역가중치 방법(IDW), (2) 다중회귀분석 (MLR), (3) 월강우를 이용한 다중회귀분석법(CMLR), (4) 국지가중치 다중회귀분석(LWP) 등이다. 보다 향상된 내삽을 위한 2단계 내삽법은 먼저 로지스틱 회귀분석으로 강우-비강우 지역을 구분하고 강우 지역에서만 기존의 내삽법을 적용하여 강우량을 구하는 방법이다. 기존 방법과의 비교결과 공간적인 편차가 심한 일강우의 특성을 2단계 내삽법에서 잘 표현하고 있는 것으로 나타났다. 제안된 방법은 수문모형에의 적용뿐만 아니라 유출량의 예보 및 대기 순환 모형의 다운 스케일링에도 효과적으로 사용될 수 있을 것으로 기대된다.

Proposal of Analysis Method for Biota Survey Data Using Co-occurrence Frequency

  • Yong-Ki Kim;Jeong-Boon Lee;Sung Je Lee;Jong-Hyun Kang
    • Proceedings of the National Institute of Ecology of the Republic of Korea
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    • 제5권3호
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    • pp.76-85
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    • 2024
  • The purpose of this study is to propose a new method of analysis focusing on interconnections between species rather than traditional biodiversity analysis, which represents ecosystems in terms of species and individual counts such as species diversity and species richness. This new approach aims to enhance our understanding of ecosystem networks. Utilizing data from the 4th National Natural Environment Survey (2014-2018), the following eight taxonomic groups were targeted for our study: herbaceous plants, woody plants, butterflies, Passeriformes birds, mammals, reptiles & amphibians, freshwater fishes, and benthonic macroinvertebrates. A co-occurrence frequency analysis was conducted using nationwide data collected over five years. As a result, in all eight taxonomic groups, the degree value represented by a linear regression trend line showed a slope of 0.8 and the weighted degree value showed an exponential nonlinear curve trend line with a coefficient of determination (R2) exceeding 0.95. The average value of the clustering coefficient was also around 0.8, reminiscent of well-known social phenomena. Creating a combination set from the species list grouped by temporal information such as survey date and spatial information such as coordinates or grids is an easy approach to discern species distributed regionally and locally. Particularly, grouping by species or taxonomic groups to produce data such as co-occurrence frequency between survey points could allow us to discover spatial similarities based on species present. This analysis could overcome limitations of species data. Since there are no restrictions on time or space, data collected over a short period in a small area and long-term national-scale data can be analyzed through appropriate grouping. The co-occurrence frequency analysis enables us to measure how many species are associated with a single species and the frequency of associations among each species, which will greatly help us understand ecosystems that seem too complex to comprehend. Such connectivity data and graphs generated by the co-occurrence frequency analysis of species are expected to provide a wealth of information and insights not only to researchers, but also to those who observe, manage, and live within ecosystems.

시변동의 동질성 증가에 의한 비단조적 시계열자료의 경향성 탐지력 향상 (Improved Trend Estimation of Non-monotonic Time Series Through Increased Homogeneity in Direction of Time-variation)

  • 오경두;박수연;이순철;전병호;안원식
    • 한국수자원학회논문집
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    • 제38권8호
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    • pp.617-629
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    • 2005
  • 본 논문은 비단조적으로 변동하는 시계열자료를 단조적으로 변화하는 구간으로 분할하여 경향성을 분석함으로써 자료의 시변동에 대한 동질성을 향상시키고 그에 따라 경향성 분석기법의 탐지력을 향상시킬 수 있다는 가설을 전제로 하고 있다. 이를 검토하기 위한 기법으로서 시계열자료의 변동경향을 파악하기 위한 필터링 방법으로 LOWESS smoothing을 적용하였고, 시계열자료의 경향성분석은 seasonal Kendall test를 적용하였다. 인위적으로 발생시킨 시계열자료와 대청호의 수온, 유량, 기온, 일사량 등의 시계열자료를 대상으로 검토한 결과 비단조적인 변화를 보이는 시계열자료를 단조적인 변화구간으로 분할하여 경향성을 분석함으로써 자료의 변동 경향성과 기울기 판정의 정확도를 높일 수 있었다. 그리고, 자료의 시변동에 대한 동질성 향상은 계절 변동성의 동질성에 대한 변화를 보다 정확하게 분석하는데 도움을 주는 것으로 보였으며 이것은 자연현상에 대한 인간활동의 영향을 고찰할 수 있는 자료로서 앞으로 이에 대한 연구가 더 필요할 것으로 보인다. 본 논문에서 제시한 방법은 시계열자료의 단조적인 경향성을 분석하는 기법들에 대해 적용 가능하며, 이를 통하여 환경변화의 경향성에 대한 보다 정확한 분석과 판단이 가능해질 것으로 기대한다.