• 대한약침학회지
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• 제19권2호
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• pp.145-154
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• 2016

Objectives: The aim of this paper is to investigate the activities of Malaysian local herbs (Clinacanthus nutans Lindau, Strobilanthes crispus, Murdannia bracteata, Elephantopus scaber Linn., Pereskia bleo, Pereskia grandifolia Haw., Vernonia amygdalina, and Swietenia macrophylla King) for anti-hypertensive and vasorelaxant activity. An infrared (IR) macro-fingerprinting technique consisting of conventional fourier transform IR (FTIR), second-derivative IR (SD-IR), and two-dimensional correlation IR (2D-correlation IR) analyses were used to determine the main constituents and the fingerprints of the Malaysian local herbs. Methods: The herbs were collected, ground into powder form, and then macerated by using three different solvents: distilled water, 50% ethanol, and 95% ethanol, respectively. The potentials of the extracts produced from these herbs for use as vasorelaxants were determined. Additionally, the fingerprints of these herbs were analyzed by using FTIR spectra, SD-IR spectra, and 2D-correlation IR spectra in order to identify their main constituents and to provide useful information for future pharmacodynamics studies. Results: Swietenia macrophylla King has the highest potential in terms of vasorelaxant activity, followed by Vernonia amygdalina, Pereskia bleo, Strobilanthes crispus, Elephantopus scaber Linn., Pereskia grandifolia Haw., Clinacanthus nutans Lindau, and Murdannia bracteata. The tri-step IR macro-fingerprint of the herbs revealed that most of them contained proteins. Pereskia bleo and Pereskia grandifolia Haw. were found to contain calcium oxalate while Swietenia macrophylla King was found to contain large amounts of flavonoids. Conclusion: The flavonoid content of the herbs affects their vasorelaxant activity, and the tri-step IR macro-fingerprint method can be used as an analytical tool to determine the activity of a herbal medicine in terms of its vasorelaxant effect.

• 지질공학
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• 제7권1호
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• pp.63-79
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• 1997

본 연구의 목적은 시간-주파수 영역에서의 미소지진과 인공폭발을 구별하는 것으로 미소지진과 인공폭발의 주파수특성을 연구하기 위해서 3차원 스펙트로그램(주파수, 시간, 진폭)을 이용하였다. 3차원 스펙트로그램은 국지 및 광역 거리에서 관측된 자료에 대하여 각각의 위상에 대한 주파수대역의 연구에 매우 유용한 방법이다. 채석장 발파로부터 관측된 P파와 S파는 Hz 이상에서 큰 진폭을 가졌고 또한 가까운 거리에서는 뚜렷한 Rg파가 관측되었다. 미소 지진의 경우 P파와 S파는 넓은 주파수 대역에서 큰 진폭이나타났다. 인공 폭발과 미소지진의 구별을 위해서는 10Hz 이하에서 Pg/Lg 스펙트럼 비를 이용하였고 각각의 위상에서의 정확한 시간창(time window)을 구하기 위해서 다중 필터 방법(MFM)을 이용하여 군속도를 계산하였다. 또한 3 성분 자료에 관해서는 자료의 순수한 P, SV, SH 성질을 구하기 위해 자유 표면에서의 영향을 보정하고 각각의 위상에 대하여 FFT을 실시하여 7개의 주파수 대역(0.5-3, 2-4, 3-5, 4-6, 5-7, 6-8, 8-10Hz)에서 Pg/Lg 스펙트럼 비를 계산하였다. 위의 과정을 통해 6-8Hz 대역에서 미소지진과 인공폭발이 가장 잘 구별되었다.

• 한국세라믹학회지
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• 제51권4호
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• pp.350-356
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• 2014

Recently, Chemical Vapor Deposition (CVD) synthetic diamonds have been introduced to the jewelry gem market, as CVD technology has been making considerable advances. Unfortunately, CVD diamonds are not distinguishable from natural diamonds when using the conventional gemological characterization method. Therefore, we need to develop a new identification method that is non-destructive, fast, and inexpensive. In our study, we employed optical microscopy and spectroscopy techniques, including Fourier transform infra-red (FT-IR), UV-VIS-NIR, photoluminescence (PL), micro Raman, and cathodoluminescent (CL) spectroscopy, to determine the differences between a natural diamond (0.30 cts) and a CVD diamond (0.43 cts). The identification of a CVD diamond was difficult when using standard gemological techniques, UV-VIS-NIR, or micro-Raman spectroscopy. However, a CVD diamond could be identified using a FT-IR by the Type II peaks. In addition, we identified a CVD diamond conclusively with the uneven UV fluorescent local bands, additional satellite PL peaks, longer phosphorescence life time, and uneven streaks in the CL images. Our results suggest that using FT-IR combined with UV fluorescent images, PL, and CL analysis might be an appropriate method for identifying CVD diamonds.

• Journal of the Optical Society of Korea
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• 제10권1호
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• pp.16-22
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• 2006

Wavefront sensing using a Shack-Hartmann sensor has been widely used for estimating wavefront errors or distortions. The sensor combines the local slopes, which are estimated from the centroids of each lenslet image, to give the overall wavefront reconstruction. It was previously shown that the pupil-plane irradiance profile effects the centroid estimation. Furthermore, a previous study reported that the reconstructed wavefront from a planar wavefront with a Gaussian pupil irradiance profile contains large focus and spherical aberration terms when there is a focus error. However, it has not been reported yet how seriously the pupil irradiance profiles, which can occur in practical applications, effect the sensing errors. This paper considered two cases when the irradiance profiles are not uniform: 1) when the light source is Gaussian and 2) when there is a partial interference due to a double reflection by a beam splitting element. The images formed by a Shack-Hartmann sensor were simulated through fast Fourier transform and were then supposed to be detected by a noiseless CCD camera. The simulations found that sensing errors, due to the Gaussian irradiance profile and the partial interference, were found to be smaller than RMS ${\lambda}/50$ when ${\lambda}$ is $0.6328\;{\mu}m$, which can be ignored in most practical cases where the reference and test beams have the same irradiance profiles.

• 한국컴퓨터정보학회논문지
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• 제11권2호
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• pp.35-42
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• 2006

본 논문에서는 Parsec을 이용하여 병렬디지털신호처리용 분산공유메모리 다중처리시스템의 성능 분석을 위한 시뮬레이터를 구현한다. 이 시뮬레이터의 특징은 TMS320C6701 DSP 칩의 DMA 기능과 빠른 접근시간을 가진 지역메모리를 사용하는 시스템의 시뮬레이션에 적합하다는 것이다. 또한 시스템의 성능 매개변수 수정과 하드웨어 구성요소들에 대한 재구성이 쉽기 때문에 다양한 실행 환경에서 시스템의 성능을 분석할 수 있다. 시뮬레이션에서는 DSP 알고리즘에서 널리 사용하는 FET, 2D FET, Matrix Multiplication, Fir Filter를 사용하여 프로세서의 수 데이터 크기, 하드웨어 요소의 변화에 따른 실행 시간을 측정한다. 그리고 그 결과를 비교함으로써 본 논문에서 구현한 시뮬레이터의 성능을 검증한다.

• 한국해양공학회지
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• 제17권3호
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• pp.46-51
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• 2003

Acoustic emission (AE) signals, emanated during local failure of aluminum alloys, have been the subject of numerous investigations. It is well known that the characteristics of AE are strongly influenced by the previous thermal and mechanical treatment of the sample. Possible sources of AE during deformation have been suggested as the avalanche motion of dislocations, fracture of brittle particles, and debonding of these particles from the alloy matrix. The goal of the present study is to determine if AE occurring as the result of fatigue crack propagation could be evaluated by the joint time-frequency analysis method, short time Fourier transform (STFT), and Wigner-Ville distribution (WVD). The time-frequency analysis methods can be used to analyze non-stationary AE more effectively than conventional techniques. STFT is more effective than WVD in analyzing AE signals. Noise and frequency characteristics of crack openings and closures could be separated using STFT. The influence of various fatigue parameters on the frequency characteristics of AE signals was investigated.

• Journal of Industrial and Engineering Chemistry
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• 제68권
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• pp.109-116
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• 2018

$Eu_2(SO_4)_3$ was synthesized by chemical precipitation method and the crystal structure was determined by Rietveld analysis. The compound crystallizes in monoclinic space group C2/c. In the air environment, $Eu_2(SO_4)_3$ is stable up to $670^{\circ}C$. The sample of $Eu_2(SO_4)_3$ was examined by Raman, Fourier-transform infrared absorption and luminescence spectroscopy methods. The low site symmetry of $SO_4$ tetrahedra results in the appearance of the IR inactive ${\nu}_1$ mode around $1000cm^{-1}$ and ${\nu}_2$ modes below $500cm^{-1}$. The band intensities redistribution in the luminescent spectra of $Eu^{3+}$ ions is analyzed in terms of the peculiarities of its local environment.

• 한국압력기기공학회 논문집
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• 제10권1호
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• pp.90-95
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• 2014

Local wall thinning is a point of concern in almost all steel structures such as pipe lines covered with a thermal insulator made up of materials with low thermal conductivity(fiberglass or mineral wool); hence, Non Destructive Technique(NDT) methods that are capable of detecting the wall thinning and defects without removing the insulation are necessary. In this study we developed a Pulsed Eddy Current(PEC) system to detect the wall thinning of Ferro magnetic steel pipes covered with fiber glass thermal insulator and shielded with Aluminum plate. The developed system is capable of detecting the wall thickness change through an insulation of thickness 10cm and 0.4mm aluminum shielding. In order to confirm the thickness change due to wall thinning, two different sensors, a hall sensor and coil sensor were used as a detecting element. In both cases, the results show a very good change corresponding to the thickness change of the test specimen. During these experiments a carbon steel tube of diameter 210mm and a length of 620mm, which is covered with insulator of 95mm thickness was used. To simulate the wall thinning, the thickness of the tube is changed for a specified length such as 2.5mm, 5mm and 8 mm from the inner surface of the tube. A 0.4mm thick Aluminum plate was covered on the Test specimen to simulate the shielding of the insulated pipelines. For both hall sensor and coil detection methods Fast Fourier transform(FFT) was calculated using window approach and the results for the test specimen without Aluminum shielding were summarized which shows a clear identification of thickness change in the test specimen by comparing the magnitude spectra. The PEC system can detect the wall thinning under the 95 mm thickness insulation and 0.4 mm Al shielding, and the output signal showed linear relation with tube wall thickness.

• The Korean Journal of Physiology and Pharmacology
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• 제15권6호
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• pp.415-422
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• 2011

Previously, we reported that besides retinal ganglion cell (RGC) spike, there is ~10 Hz oscillatory rhythmic activity in local field potential (LFP) in retinal degeneration model, rd1 mice. The more recently identified rd10 mice have a later onset and slower rate of photoreceptor degeneration than the rd1 mice, providing more therapeutic potential. In this study, before adapting rd10 mice as a new animal model for our electrical stimulation study, we investigated electrical characteristics of rd10 mice. From the raw waveform of recording using $8{\times}8$ microelectrode array (MEA) from in vitro-whole mount retina, RGC spikes and LFP were isolated by using different filter setting. Fourier transform was performed for detection of frequency of bursting RGC spikes and oscillatory field potential (OFP). In rd1 mice, ~10 Hz rhythmic burst of spontaneous RGC spikes is always phase-locked with the OFP and this phase-locking property is preserved regardless of postnatal ages. However, in rd10 mice, there is a strong phase-locking tendency between the spectral peak of bursting RGC spikes (~5 Hz) and the first peak of OFP (~5 Hz) across different age groups. But this phase-locking property is not robust as in rd1 retina, but maintains for a few seconds. Since rd1 and rd10 retina show phase-locking property at different frequency (~10 Hz vs. ~5 Hz), we expect different response patterns to electrical stimulus between rd1 and rd10 retina. Therefore, to extract optimal stimulation parameters in rd10 retina, first we might define selection criteria for responding rd10 ganglion cells to electrical stimulus.

• 대한의용생체공학회:의공학회지
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• 제19권2호
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• pp.113-118
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• 1998

인체의 기도 내 섬모 세포는 세포간의 동기화된 고 속의 움직임을 통하여 호흡기를 통하여 들어오는 유해한 물질을 제거하는 중요한 역할을 한다. 본 논문에서는 자동화된 영상처리 기법을 기반으로 CBF를 객관적이고 정량적인 방법으로 측정할 수 있는 방법을 연구하였다. 광학 현미경의 세포 영상은 영상 수집 보드를 통하여 연속적으로 디지털화 된다. 이러한 디지털 영상으로부터 분석에 필요한 신호가 추출되고 분석된다. 획득된 영상을 현미경의 배율을 고려하여 적당한 크기의 사각형 블록으로 나눈 다음 각각에 대하여 FFT 방법에 의해 파워 스펙트럼을 구한다. 파워 스펙트럼의 최고치 주파수가 CBF로 간주되고 이 주파수들을 이용하여 영상 필드 내의 CBF분포를 시각적으로 보여주는 CBF 분포도가 구성된다. 스펙트럼의 최고치 주파수가 CBFD로 간주되고 이 주파수들을 이용하여 영상 필드 내의 CBF 분포를 시각적으로 보여주는 CBF분포도가 구성된다. CBF분포도는 세포간의 CBF차이를 쉽게 구분할 수 있게 해줄 뿐만 아니라 CBF분포의 전체적인 변화 양상을 파악하기 쉽게 해준다. 관찰자가 지정하는 다각형의 윈도우 내의 CBF히스토그램 분포를 통하여 세포 또는 세포 크러스트의 특정 부분의 CBF를 측정할 수 있다.