• Title/Summary/Keyword: local circulation

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The effect of coenzyme Q10 on endothelial function in a young population

  • Petrofsky, Jerrold;Laymon, M.;Lee, H.;Hernandez, E.;Dequine, D.;Thorsen, L.;Lovell, R.;Andrade, J.
    • Physical Therapy Rehabilitation Science
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    • v.1 no.1
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    • pp.6-12
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    • 2012
  • Objective: Coenzyme (CoQ10) is an enzymatic co factor used in normal cellular metabolism. Recent evidence shows that in people with heart disease it can reverse endothelial cell damage in the blood vessels. It is also a potent antioxidant. Design: One group pretest-posttest design. Methods: In the present study, endothelial function was evaluated using the response to occlusion and heat before and 2 weeks after administration of CoQ10, 300 mg/day. Thirty Eight subjects, who are physical therapy students, participated in a series of experiments to see if taking 300 mg of CoQ10 daily for 2 weeks would impact resting blood flow in the forearm skin and the blood flow response to 4 minutes of vascular occlusion and the response to local heat ($42^{\circ}C$) for 6 minutes. Results: The results showed that, for this population, there was no difference in the response to heat. However, the response to occlusion was improved after administration of CoQ10. Conclusions: It would appear that in a young population CoQ10 has no effect on the nitric oxide vasodilator pathway in skin but does influence other vasodilator pathways.

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Flow and Heat Transfer Characteristics due to the Variations of the Angle of Attack at the Vortex Generators located behind a Circular Cylinder (원주 후미에 부착된 와동발생기의 영각 변화에 따른 유동 및 열전달 특성)

  • 하홍영;홍철현;양장식;이기백
    • Journal of Advanced Marine Engineering and Technology
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    • v.26 no.4
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    • pp.439-449
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    • 2002
  • Experimental investigations of the flow structure and heat transfer enhancement in a channel with a built-in circular cylinder and a wing-let type vortex generator are presented. Without any vortex generators, relatively low heat transfer takes place in the downstream of the circular cylinder where is a recirculation region with low velocity fluid is formed. However with a wing-let type longitudinal vortex generator in the wake region behind the cylinder, heat transfer in the region can be enhanced. In order to control the strength of longitudinal vortices, the angle of attack of the vortex generators is varied from $20^{circ} to 45^{\circ}$, but spacings between the vortex generations are fixed to be 5 mm. The 3-dimensional mean velocity field downstream of the vortex generator is measured by a five-hole pressure probe, and the hue-capturing method using thermochromatic liquid crystals has been used to provide the local distribution of the heat transfer coefficient. The vorticity field and streamwise velocity contour are obtained from the velocity field. Streamwise distributions of averaged Stanton number on the measurement planes show very similar trends for all the experimental cases($\beta=20^{circ}, 30^{circ} and 45^{\circ}$). Circulation strength and heat transfer coefficient have the maximum values when the angle of attack($\beta$) is $30^{\circ}$.

Numerical Simulation of Flows inside the Various Rooms for Performance Assessment of Air Cleaning System (공기청정 시스템 성능예측을 위한 실내 유동현상에 관한 수치모사)

  • 손덕영;이두환;길재흥;최윤호;김동현
    • Journal of Energy Engineering
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    • v.11 no.4
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    • pp.306-316
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    • 2002
  • ln this paper, flowfields inside the various rooms have been investigated. A storage room, a liv-ingroom with a kitchen in an apartment, and a hospital room are considered in the present calculations. In all cases, it was found that the average of air change rate is. similar to that of perfect mixing assumption and the location of air purifier has little effects on the average air change rate. Detailed local air concentrations show that there are regions where air is not quite purified because of non-uniform circulation of air flow. The location of air purifier has great effects on this behavior.

A Study on the Value of S Children's Library (어린이도서관의 가치에 관한 연구 - S어린이도서관을 중심으로 -)

  • Cho, Keum-Ju
    • Journal of Korean Library and Information Science Society
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    • v.42 no.1
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    • pp.51-72
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    • 2011
  • This work investigated the social, cultural, and economical impacts of the services that S Children's Library provides to local community and its residents. In this study I analyzed the user statistics by using Korean Library Automation System III, practiced a comparative analysis with other libraries over circulation efficiency, and reviewed the user's evaluation through user survey. The achievement of this study is to find out the value of S Children's Library by verifying the service status of S Children's Library based on the analyzed data, assessing the role and meaning of the children's library within the community, and measuring the economical contribution through user evaluation.

Avian Gut Immune System and Local Responses to Eimerial Parasites (조류의 장내 면역체계와 콕시듐(Eimeria)기생충들에 대한 국소면역 반응)

  • Lillehoj, H.S.
    • Korean Journal of Poultry Science
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    • v.26 no.2
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    • pp.131-144
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    • 1999
  • Coccidiosis, an intestinal infection caused by intracellular protozoan parasites belonging to several different species of Eimeria seriously impairs the growth and feed utilization of livestock and poultry. Due to complex life cycle of organism and intricate host immune responses to Elmeria, coccidia vaccine development has been difficult. Understanding of basic imunobiology of pertinent host-parasite interactions is necessary for the development of novel control strategy. Although chickens infected with Eimeria spp. produce parasite-specific antibodies in both the circulation and mucosal secretions, antibody mediated responses play a minor role in protection gainst coccidiosis. Rather, increasing evidence show that cell-mediated immunity plays a major role in resistance to coccidiosis. T-lymphocytes appear to respond to coccidiosis both through cytokine production and a direct cytotoxic attack on infected cells. The exact mechanisms by which T-cells eliminate the parasites, however, remain to be investigated. Since it is crucial to understand the intestinal immune system in order to develop an immunological control strategy against any intestinal immune system in order to develop an immunological control strategy against any intestinal diseases, this presentation will summarize our current understanding of the avian intestinal immune system and mucosal immune responses to Eimeria, to provide a conceptual overview of the complex molecular and cellular events involved in intestinal immune responses to enteric pathogens.

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Space Composition Characteristics Analysis of the Community-Centered Shared Office (공유오피스의 커뮤니티 중심 공간 구성 특성)

  • Lee, hye-su;Nam, Kyung-Sook
    • Korean Institute of Interior Design Journal
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    • v.27 no.1
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    • pp.3-11
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    • 2018
  • The number of shared offices has increased and changed within the flow of the era into various forms in recent days. Co-working spaces and related shared space businesses are growing fast, keeping pace with the trend recently. It is confirmed that the need of spaces grew 180% since 2015 to 2017. Most of the shared offices in Seoul are placed in Gangnam circle, it is verified that shared office is providing work, space, and community by visiting cases of foreign companies, domestic companies, local companies. Meanwhile, shared space can be categorized into serviced office, co-working space, virtual office, and daily office. It is to consider various target levels by leasing service or the difference of costs. It is divided into forms of dispersion, circulation, and concentration and is planned to increase the utilization of communities' traffic according to the allocation of shared office. The business is conducted network-centered. During the process of communication, members can get chances to exchange and build communities. They are making business ecosystem which they can coexist and grow together. Shared offices have a view of a solution to empty rooms and will last for a while, and it is expected that co-working system be settled as office space and giving people sense of belonging on their workspace.

Chemical Imprints of the Upwelled Waters off the Coast of the Southern East Sea of Korea

  • Lee, Tong-Sup;Kim, Il-Nam
    • Journal of the korean society of oceanography
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    • v.38 no.3
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    • pp.101-110
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    • 2003
  • We made intensive observations on the coastal upwelling off the coast of the southern East Sea from June to August in 2001. The upwelling exhibited a weekly waxing and waning. The coastal upwelling of the year 2001 was characterized by abrupt outbreaks and the small local scale. Upwelling occurred more frequently off the coast of Ulsan and Gampo as reported by the earlier observers. The spread of freshly upwelled colder water was varied by each upwelling event. Generally cold waters were carried away northeastward off Pohang province. The upwelled cold waters were saltier than the resident surface waters. The pH and salinity-normalized alkalinity support the idea that the upwelled waters originate from the interior of the East Sea. The extraordinarily high concentration of dissolved oxygen suggests that the upwelled waters are closely connected to the southward flowing North Korea Cold Current. Although a lower primary productivity was reported for the upwelling region, underway surface fluorescence measurement revealed that the recently upwelled waters supported up to an order of magnitude higher algal biomass than the ambient waters. Because thermohaline circulation of the East Sea is so vigorous, with an estimated time scale of less than one hundred years, that the coastal upwelling should be considered not as an anomaly but as a regular component of a circulatory system. A quantitative understanding of upwelling seems to be a key to elucidate material cycling and the associated biological production in the East Sea.

A Study on Space alteration by User's Independent Management in Children's Library (어린이도서관에 있어서 이용자의 자주적 관리에 의한 공간변화에 관한 연구)

  • Cheon, Hye-Sun;Lee, Jeong-Mi;Kwack, Dong-Wha;Lim, Che-Zinn;Lee, Sang-Bok
    • Korean Institute of Interior Design Journal
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    • v.18 no.2
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    • pp.93-101
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    • 2009
  • This study is including the independent project, "building children's library of the town" that is conducted by a local resident. The study object is the contents of the "design workshop for library planning" and the general process during one year since the opening. This study is delivering "information of children's library" through the work-shop and is conducting the role of a professional space planner by measuring the blueprint. Thus, the study could be conducted with synthetic viewpoint on each library. The followings are the results from the study. First, there were various space operations and a variety of programs in the case library that is independently managed. This is directing to "the constructive and active space usage" by the users and finally results in positive circulation. Secondly, there is a change through the process of execution and operation in the library construction plan. There are needs for the flexible space expansion and adjustment, modifiable furniture layout and design and various keeping areas because there is on-going tendency of corresponding space change. The third, the author could draw more practicable consideration points for space planning by looking at the trend of space change in Transactionist viewpoint. Thus, this study is very meaningful in terms of planning of sustainable public areas.

A Study on the Planning of the Eco-Villages for Aging Society - Focused on the Cases of the Environmental Co-Housings in Western America - (고령화 사회를 위한 생태 공동주거 계획에 관한 연구 - 미 서부 생태 공동주거 단지 사례를 중심으로 -)

  • Koo, Jae Oh
    • KIEAE Journal
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    • v.10 no.3
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    • pp.111-116
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    • 2010
  • Ecological villages should be designed not only for simply reducing environmental impact such as energy saving and alternative energy use, resource conservation and circulation, harmony with surrounding environment and nature, but also for encouraging social contact and community activities with the residents, especially the aged people. The aim of this paper is to find the ecological and social design elements for the ecological village planning derived through case studies. The case studies are selected from the environmental Co-housings in Western America, surveyed in the years of 2008 and 2009. The results are as follows; 1. The ecological design elements, although there are some differences in size and type, were found to be basically applied in every ecological villages. 2. The community activities are actively conducted with the participation of the residents based on a variety of programs. The two main purposes of the community activities are strengthening the residents' familiarity with each other and the volunteer services to the local community where they belong.

Review of Operational Multi-Scale Environment Model with Grid Adaptivity

  • Kang, Sung-Dae
    • Environmental Sciences Bulletin of The Korean Environmental Sciences Society
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    • v.10 no.S_1
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    • pp.23-28
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    • 2001
  • A new numerical weather prediction and dispersion model, the Operational Multi-scale Environment model with Grid Adaptivity(OMEGA) including an embedded Atmospheric Dispersion Model(ADM), is introduced as a next generation atmospheric simulation system for real-time hazard predictions, such as severe weather or the transport of hazardous release. OMEGA is based on an unstructured grid that can facilitate a continuously varying horizontal grid resolution ranging from 100 km down to 1 km and a vertical resolution from 20 -30 meters in the boundary layer to 1 km in the free atmosphere. OMEGA is also naturally scale spanning and time. In particular, the unstructured grid cells in the horizontal dimension can increase the local resolution to better capture the topography or important physical features of the atmospheric circulation and cloud dynamics. This means the OMEGA can readily adapt its grid to a stationary surface, terrain features, or dynamic features in an evolving weather pattern. While adaptive numerical techniques have yet to be extensively applied in atmospheric models, the OMEGA model is the first to exploit the adaptive nature of an unstructured gridding technique for atmospheric simulation and real-time hazard prediction. The purpose of this paper is to provide a detailed description of the OMEGA model, the OMEGA system, and a detailed comparison of OMEGA forecast results with observed data.

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