• 제목/요약/키워드: liquid crystaline phase

검색결과 1건 처리시간 0.016초

액정상을 이용한 O/W형 에멀젼의 제조 및 제형 안정화에 관한 연구 (Preparation and Stabilization of an O/W Emulsion Using Liquid Crystalline Phases)

  • 안봉전;이진태;이인철;곽재훈;박정미;박찬익
    • 한국응용과학기술학회지
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    • 제21권1호
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    • pp.31-36
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    • 2004
  • Liquid crystalline phases were formed from acylglutamate; polyglyceryl-10 myristate and glycerine mixture and they were used as a base material for preparing an O/W emulsion. When an oil phase is added into the liquid crystalline phases, it was inserted into the dispersed liquid crystal droplets rather than stayed outside the liquid crystals, which can be known by the fact that the size of liquid crystal droplets increases with the increasing oil phase content. Along with the increase in the droplet size, the complex modulus increases from 100 to 350 pascals and the loss angle decreases from 60 to 24 degrees, from which it can be known that the increase in the internal phase volume results in the increase in the elastic property of oil in liquid crystalline-phases (O/LC). When the water phase was lastly added into the O/LC phase, the emulsification occurred to form a O/W emulsion and the averaged particle size of the O/W emulsion changes from 22.5nm to 538nm with the addition of water phase. The results from the droplet size measurements and stability tests under accelerated conditions such as high temperature show that the obtained O/W emulsion is very consistent with time.