• Investigative Magnetic Resonance Imaging
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• 제26권1호
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• pp.66-70
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• 2022

Paratesticular liposarcoma is a very rare tumor that is typically reported as isolated cases of or as components of larger studies of liposarcomas. Image findings are similar to those of other anatomic sites, but in less-common sites, their appearance may be less familiar, and they may be mistaken for other pathologies. In addition, atypical image findings of liposarcoma make diagnosis more difficult. Herein, we report on the case of a 45-year-old male patient who presented with a painless, palpable mass in the right scrotum. The patient was diagnosed with paratesticular liposarcoma by excisional biopsy.

• 대한두경부종양학회지
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• 제19권1호
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• pp.71-74
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• 2003

Liposarcoma is one of the most common malignancies originating from human soft tissue. Because most of liposarcoma occur in the lower extremities or retroperitoneum, there are few reports about liposarcoma of head and neck region, including larynx and pharynx. Histologically, there are four types of liposarcoma, and prognosis and recurrence rate are different according to histologic subtype. Wide excision is the treatment of choice and liposarcoma hardly respond to primary radiotherapy. A 56-year-old man presented with voice change and foreign body sensation in laryngopharynx. Hypopharyngeal liposarcoma was diagnosed by surgical biopsy and performed totallaryngopharyngoesophagectomy and gastric pull-up. Here we report our experience on this case with review of literature.

• Archives of Plastic Surgery
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• 제34권1호
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• pp.119-122
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• 2007

Purpose: Although liposarcoma is the second most common soft tissue sarcoma in adults, the incidence of liposarcoma of the head and neck is rare. There is only one reported case in Korea and moreover, only in adolescence. We report a case of liposarcoma on the neck in a 32-year-old male in adult. Methods: The patient had a slow growing, none tender mass on the posterior neck without lymphadenopathy, which has been present for 3 years and recurred twice during that time. MRI showed a 1.5 cm sized ovoid, well demarcated mass that was located in the subcutaneous layer of the posterior neck. Results: The mass was surgically removed. The resection margin was free of tumor on frozen biopsy and histopathologic examination indicated myxoid and round cell liposarcoma. The whole body F-18 FDG PET-CT applied on the fourteenth day postoperatively, revealed a moderate FDG-uptaking soft tissue lesion showing postoperative wound healing process on the posterior neck region and there was no distant metastasis. Conclusion: Liposarcoma is the second most common soft tissue sarcoma in adults. But, it rarely involves the head and neck region. Prognosis is principally dependent on histologic subtype and grade. Low grade liposarcoma such as well differentiated and myxoid liposarcoma tend to recur locally, rarely metastasize. On the other hand, high grade liposarcoma such as round cell and pleomorphic liposarcoma have higher rates of local recurrence and distant metastasis. Complete surgical excision provides the most effective means of treatment. Radiotherapy or chemotherapy can be used as an asjunctive treatment modality.

• 대한두경부종양학회지
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• 제28권2호
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• pp.139-142
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• 2012

Liposarcoma is the second most common soft tissue sarcoma in adult. The incidence of liposarcoma in the head and neck area is very uncommon. Liposarcoma of the neck usually express non-tender palpable mass. The main treatment of cervical liposarcoma is surgical excision and adjuvant radiation therapy. Herein, we report a case of cervical liposarcoma with the review of literature.

• Investigative Magnetic Resonance Imaging
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• 제21권4호
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• pp.252-258
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• 2017

Primary mesenteric liposarcoma is rare. It is difficult to make an accurate preoperative diagnosis of the myxoid type of liposarcoma by using imaging such as ultrasound or computed tomography (CT) due to the very small amount of fat that is located in the tumor. We report a case of primary myxoid liposarcoma of the mesentery which was difficult to differentiate from other solid mesenteric tumors with a myxoid component such as low grade fibromyxoid sarcoma, myxoid leiomyosarcoma or myxoma. Use of chemical shift magnetic resonance (MR) imaging to detect small fat components and its cystic appearance with solid components on the MR images can be useful to differentiate myxoid liposarcoma from the other mesenteric tumors with a myxoid component.

• Journal of Chest Surgery
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• 제37권11호
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• pp.942-945
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• 2004

원발성폐지방육종은 극히 드문 질환일 뿐만 아니라, 국소재발이 빈번하고 발병 초기에 원격전이가 발생하여 예후가 불량한 질환이다. 지방육종의 치료를 위해서는 수술적인 절제가 우선적이나, 완전히 절제를 못하였을 경우 지방육종이 국소적으로 재발하게 되고 상당히 빠른 속도로 자라게 된다. 저자들은 원발성폐지방육종을 완전 절제하여 10개월 간 재발 및 전이가 없는 예를 경험하였기에 보고하는 바이다.

• 임상이비인후과
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• 제29권2호
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• pp.295-300
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• 2018

Pleomorphic liposarcoma is extremely rare in the head and neck region. It can be diagnosed by identifying multivacuolated lipoblast with pleomorphism. Most studies have reported that pleomorphic liposarcoma shows an aggressive behavior with poor prognosis. The treatment of choice is wide resection to ensure negative margin. The authors report a case of pleomorphic liposarcoma in a 67-year-old female, who was treated with primary resection of tumor and postoperative radiation therapy. The patient is well without any recurrence or metastasis after 1 year of follow-up.

• 대한두경부종양학회지
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• 제37권2호
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• pp.71-75
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• 2021

Liposarcoma is a very rare malignant tumor affecting the head and neck area. Since it is an invasive and life-threatening disease, active treatments is necessary. However, differential it from lipoma, its corresponding benign counterpart, may be difficult. Herein, we report a rare case of posterior neck myxoid liposarcoma in a 72-year-old man who was initially misdiagnosed with lipoma, including a literature review of differential diagnosis between lipoma and liposarcoma.

• 대한두경부종양학회지
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• 제26권2호
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• pp.256-258
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• 2010

Although liposarcoma is the second most common soft tissue sarcoma in adults, the incidence of liposarcoma in the head and neck is low. The histologic nature of liposarcoma is correlated clinically with treatment outcome, but histologic classification of liposarcoma is controversial. Well-differentiated liposarcoma and atypical lipoma are pathologic synonyms because they are identical lesions both morphologically and karyotypically. They represent the lowest grade lesions in the spectrum of liposarcoma. The terms "atypical lipoma" were introduced specifically to describe well-differentiated liposarcomas occurring in the extremities, because of their better prognosis in comparison with their retroperitoneal counterparts. We present 1 case of atypical lipomatous tumor of the neck.

• 대한정형외과학회지
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• 제55권4호
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• pp.331-337
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• 2020

목적: 지방육종의 치험 예들을 분석하여 생존율에 영향을 미치는 예후 인자를 밝히고, 향후 효과적인 치료의 접근에 도움이 되고자 한다. 대상 및 방법: 2002년부터 2015년까지 지방육종으로 진단, 치료받은 환자 총 45예 중 고분화 지방육종 4예를 제외한 41예를 분석하였다. 성별, 나이, 발생 부위, 병기, 조직학적 분류, 방사선 치료, 항암 화학 치료 등이 무병 생존율에 미치는 영향에 대한 후향적 연구를 시행하였다. 점액성 지방육종으로 진단된 28예에 대해서는 원형세포 성분 포함 여부에 따른 분석을 추가로 진행하였다. 결과: 진단 시 평균 연령은 52.05세(25-82세), 평균 추시 기간은 63.7개월이었으며, 평균적인 무병 생존율은 41.7%였다. 점액성 지방육종의 경우 무병 생존율은 43.2%였다. 분석 결과 나이, 발생 부위 조직학적 분류 등은 무병 생존율에 영향을 미치지 못하였으나 병기(Musculoskeletal Tumor Society stage)와 성별에서 통계적으로 유의한 연관을 나타내었다. 점액성 지방육종에 대해서는 원형세포 성분에 따른 결과의 차이를 보이지 않았다. 결론: 지방육종의 병기와 환자의 성별이 예후에 영향을 미치는 유효한 인자로 나타났다. 지방육종은 여러 예후 인자들에 의해 치료 결과에 차이를 보이므로, 치료에 있어 이러한 점을 고려하여야 한다.