• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.1
• /
• pp.1-13
• /
• 2012

Metabolic syndrome has become quite prevalent within our society. Over the past two decades, the prevalence of metabolic syndrome has sharply increased worldwide and it has become a major public health problem in several countries. It is associated with the global epidemic of obesity and diabetes mellitus and imposes numerous cardiovascular risks. Prostate cancer is the second most common cancer among men, surpassed only by non-melanoma skin cancer. A considerable body of evidence exists suggesting that some components of the metabolic syndrome have been associated with the risk of prostate cancer. These components include obesity, an abdominal fat distribution, and hyperinsulinemia. Androgen deprivation therapy (ADT) is the most widely used therapeutic modality in prostate cancer. It changed the body composition and lipid profile of men with prostate cancer. Androgen deficiency is associated with increased levels of total cholesterol, low-density lipoprotein (LDL)-cholesterol, increased production of proinflammatory factors, and increased thickness of the arterial wall and contributes to endothelial dysfunction. The aim of this review is to evaluate the association between metabolic syndrome and prostate cancer and to discuss the implications of androgen deficiency in men with cardiovascular risk factors. A comprehensive literature search was carried out with the use of PubMed from 1980 through 2011, and relevant articles pertinent to metabolic syndrome and prostate cancer are evaluated and discussed.

• Proceedings of the KIPE Conference
• /
• 2003.07a
• /
• pp.317-322
• /
• 2003

A novel three-level DC/DC converter (TLC)for high power applications operating from high input voltage Is proposed. Its switch voltage stress can be ensured to be only one-half of the Input voltage. Nevertheless, since all input voltage is applied to the transformer primary side, it has good turns ratio. The driving method of each module is same as those of the conventional phase-shifted ZVS full bridge PWM converter (PSFB) and the zero-voltage-switching (ZVS) of the leading leg are achieved exactly in the same manner as that of the PSFB. Moreover, its three-level operation can considerably reduce the current ripple through the output inductor and it has no problems of the DC-link voltage unbalance. Therefore, it features a low voltage stress, high efficiency, low EMI, high power density, and small sized filter. To confirm the operation, validity, and features of the proposed circuit, experimental results from a 200W, 600V/DC-48V/DC prototype are presented.

• Korean Journal of Weed Science
• /
• v.7 no.3
• /
• pp.247-256
• /
• 1987

The ability of three Echinochloa colona (L.) Link ecotypes to compete with rice (Oryza sativa L.) was evaluated. For all the ecotypes, E. colona was shorter and produced less leaf area and dry matter than rice at 15 days after seeding (DAS), whereas the reverse was observed from 30 to 60 DAS. Neither E. colona nor rice tillered during the first 15 DAS, but E. colona had greater accumulative tiller length than rice from 15 DAS. Rice absorbed more nitrogen than E. colona at 15 DAS. E. colona absorbed greater amounts of nitrogen, phosphorus, and potassium than did rice between 30 and 60 DAS and increase in its density decreased the nutrients uptake of rice. Differences in the competitive ability of the ecotypes were related to the growth characteristics of the ecotypes and the period of competition between the two species. At the early growth stages the Pangasinan ecotype, which increased plant size rapidly and had a shorter life cycle, was more competitive against rice than the Leyte and South Cotabato ecotypes, which had a longer vegetative growth period. However, the reverse was observed at the later growth stages of the ecotypes.

• Environmental Analysis Health and Toxicology
• /
• v.14 no.4
• /
• pp.203-216
• /
• 1999

This paper describes a set of multi-pathway models for estimating health risk to lead. The models link concentrations of an environmental contaminant (lead) in air, water and food to human exposure through inhalation, ingestion, and dietary routes. Exposure is used as the foundation for predicting risk of health detriment within the population. The process of estimating exposure using often limited data and extrapolating to a large diverse population requires many assumption, inferences, and simplification. This paper is divided into four section. The first section provides lead contaminant levels on obtaining environmental concentration of air, tap water, and foods. The second section provides a discussion of exposure parameters and uncertainty associated predicting human health risk of contaminants. The third and fourth section illustrate lifetime average daily exposure (LADE) and excess cancer risk (ECR) based on exposure parameters. The relationship between concentration of lead in an environmental medium and human exposure is determined with pathway exposure factors (PEFs). The calculation of LADE and ECR is carried out using Monte-Carlo simulation with probability density function of exposure parameters. Examination of the result reveals that, for lead exposure, ingestion (food) is the dominant route of exposure rather than inhalation (air), and ingestion (tap eater).

• International Journal of Contents
• /
• v.11 no.1
• /
• pp.7-14
• /
• 2015

In this paper, we derive the outage probability for M-ary phase shifting keying (MPSK) and M-ary quadrature amplitude modulation (MQAM) burst transmission (BT) of adaptive decode-and-forward (ADF) cooperative relay systems over quasi-static Rayleigh fading channels. Within a burst, there are pilot symbols and data symbols. Pilot symbols are used for channel estimation schemes and each relay node's transmission mode selection schemes. At first, we focus on ADF relay systems in which the probability density function (PDF) is derived on the basis of error events at relay nodes corresponding to channel estimation errors. Next, the average outage probability is derived as an approximate expression for an arbitrary link signal-to-noise ratio (SNR) for different modulation orders. Its accuracy is demonstrated by comparison with simulation results. Further, it is confirmed that BT-ADF relay systems with pilot symbol based channel estimation schemes enables to select correctly decoded relay nodes without additional signaling between relay nodes and the destination node, and it is verified that the ideal performance is achieved with small SNR loss.

• Biomedical Science Letters
• /
• v.26 no.3
• /
• pp.164-169
• /
• 2020

Atherosclerosis is a cardiovascular disease in which plaque builds up inside of an artery and can lead to various complications such as myocardial infarction, stroke, and thrombosis. Recently, hypertriglyceridemia has attracted significant attention as contributors to development of atherosclerosis. However, molecular mechanism of its contribution to atherosclerosis is poorly understood. Here we proposed a potential link between triglyceride (TG) and atherosclerosis. TG treatment promoted downregulation of certain scavenger receptor, macrophage scavenger receptor-1 (MSR-1) in phorbol myristate acetate (PMA)-derived human macrophages. TG treatment caused reduction of MSR-1 mRNA expression in a time- and dose-dependent manner. Using chemical inhibitors, we found that inhibition of signaling pathways associated with PI3K and PLC enhances TG-induced reduction of MSR-1 expression in THP-1 macrophages implying that PI3K and PLC is implicated in the expression of MSR-1 in macrophages. Since MSR-1 is associated with uptake and clearance of atherogenic lipoprotein, oxidized low density lipoprotein (oxi-LDL), our data suggest that increase of oxi-LDL due to TG-mediated reduction of its receptor MSR-1 can promote atherosclerosis.

• 한국신재생에너지학회:학술대회논문집
• /
• 2007.11a
• /
• pp.47-51
• /
• 2007

The present paper reports the life time prediction of Acrylonitrile-Butadiene rubber (NBR) fuel cell gasket materials as a function of operational variables like acid concentration, ageing time and temperature. Both material and accelerated acid-heat aging tests were carried out to predict the useful life of the NBR rubber gasket for use as a fuel cell stack. The acid ageing of the gasket compounds has been investigated at 120, 140 and $160^{\circ}C$, with aging times from 3 to 600 h and increasing acid ($H_2SO_4$) concentrations of 5, 6, 7 and 10 vol%. Material characteristics the gas compound such as cross-link density, tensile strength and elongation at break were studied. The hardness of the NBR rubber was found to decrease with decreasing acid concentration at both 120 and $140^{\circ}C$, but at $160^{\circ}C$ interestingly the hardness of the NBR rubber increased abruptly in a very short time at different acid concentrations. The tensile strength and elongation at break were found to decrease with increase in both the acid concentrate ion & temperature. The life time of the compounds were evaluated using the Arrhenius equation.

• Proceedings of the Korean Vacuum Society Conference
• /
• 2014.02a
• /
• pp.242.2-242.2
• /
• 2014

Plasma-polymer thin films (PPTF) have been deposited on a Si(100) wafer and glass under several conditions such as different RF power by using plasma-enhanced chemical vapor deposition (PECVD) system. Ethylcyclohexane, ammonia gas, hydrogen and argon were utilized as organic precursor, doping gas, bubbler gas and carrier gases, respectively. PPTFs were grown up with RF (ratio frequency using 13.56 MHz) powers in the range of 20~60 watt. PPTFs were characterized by FT-IR (Fourier Transform Infrared), FE-SEM (Scanning Electron Microscope), AFM (Atomic Force Microscope), Contact angle and Probe station. The result of FT-IR measurement showed that the PPTFs have high cross-link density nitrogen doping ratio was also changed with a RF power increasing. AFM and FE-SEM also showed that the PPTFs have smooth surface and thickness. Impedance analyzer was utilized for the measurements of C-V curves having different dielectric constant as RF power.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.25 no.5A
• /
• pp.641-650
• /
• 2000

The effects of noise and doppler for low orbit satellite range measurement using tone method are represented in this paper. Also the optimal noise bandwidth of range signal detection circuit which is used for range measurement system of KOMPSAT is proposed. Based on the effects of satellite orbit parameters via the deduction of dynamic motion characteristics of low orbit satellite and signal to noise spectral density of range measurement signal, the effects of noise and doppler for range measurement system are analyzed. The effect of satellite link noise is decreased, but the effect for doppler is increased as the PLL noise bandwidth of range signal detection circuit is increased. The validation of analyzed effect is verified via comparison of measurement results of KOMPSAT's range measurement system and simulation results in environments of low orbit satellite.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.10 no.5
• /
• pp.2144-2165
• /
• 2016

In a vehicular ad hoc network, the communication links are unsteady due to the rapidly changing topology, high mobility and traffic density in the urban environment. Most of the existing geographical routing protocols rely on the continuous transmission of beacon messages to update the neighbors' presence, leading to network congestion. Source-based approaches have been proven to be inefficient in the inherently unstable network. To this end, we propose an opportunistic beaconless packet forwarding approach based on a modified handshake mechanism for the urban vehicular environment. The protocol acts differently between intersections and at the intersection to find the next forwarder node toward the destination. The modified handshake mechanism contains link quality, forward progress and directional greedy metrics to determine the best relay node in the network. After designing the protocol, we compared its performance with existing routing protocols. The simulation results show the superior performance of the proposed protocol in terms of packet delay and data delivery ratio in realistic wireless channel conditions.