• Title/Summary/Keyword: linear mixed effect model

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The wage determinants of the vocational high school graduates using mixed effects mode (혼합모형을 이용한 특성화고 졸업생의 임금결정요인 분석)

  • Ryu, Jangsoo;Cho, Jangsik
    • Journal of the Korean Data and Information Science Society
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    • v.27 no.4
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    • pp.935-946
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    • 2016
  • In this paper, we analyzed wage determinants of the vocational high school graduates utilizing both individual-level and work region-level variables. We formulate the models in the way wage determination has multi-level structure in the sense that individual wage is influenced by individual-level variables (level-1) and work region-level (level-2) variables. To incorporate dependency between individual wages into the model, we utilize hierarchical linear model (HLM). The major results are as follows. First, it is shown that the HLM model is better than the OLS regression models which do not take level-1 and level-2 variables simultaneously into account. Second, random effects on sex, maester dummy and engineering dummy variables are statistically significant. Third, the fixed effects on business hours and mean wage of regular job for level-2 variables are statistically significant effect individual-level wages. Finally, parental education level, parental income, number of licenses and high school grade are statistically significant for higher individual-level wages.

EFFECT OF THE SURFACE MODIFICATIONS AND THE USE OF WASHER ON THE REVERSE TORQUE OF THE IMPLANT PROSTHETIC GOLD RETAINING SCREW

  • Lee, Jae-Hyuck;Jang, Kyung-Soo;Kim, Chang-Whe;Kim, Yung-Soo
    • The Journal of Korean Academy of Prosthodontics
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    • v.40 no.3
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    • pp.246-261
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    • 2002
  • The screw loosening is one of the complications that happen frequently in dental implant prostheses. The purpose of this study was to evaluate the changes of reverse/loosening (opening) torque of the screw according to the surface modifications by sandblasting and 24K gold electroplating as well as to determine the possibility of the clinical use of a washer in dental implant. The reverse torque of 4 experimental conditions(control, sandblasted, use of washers, electroplasted) was measured by digital torque gauge (Model MGT50Z, Mark-10 Corp., 458 West John Street Hicksville, NY 11801 USA). Electronic torque controller (Nobel Biocare DEA 020) was used in fastening the gold screws into abutment replicas. Mixed Linear Model Analysis method was used for statistical analysis. To examine the changes of screw thread surface, microphotographs were taken by Olympus PME-3 metallurgic microscope (Olympus Optical Co. Ltd., Tokyo, Japan). Within the limitations of this study, the following results were drawn: 1. The surface modifications of the gold screws and the use of a washer have significantly affected the reverse torque value compared to the control group (P<0.01). 2. Sandblasting and electroplating treatments demonstrated significantly higher reverse torque value than that of control group. 3. The use of a washer may be one of the useful clinical methods that prevent the screw loosening. However, further studies are necessary for the material selection and design of the washer.

Mercury Exposure in Association With Decrease of Liver Function in Adults: A Longitudinal Study

  • Choi, Jonghyuk;Bae, Sanghyuk;Lim, Hyungryul;Lim, Ji-Ae;Lee, Yong-Han;Ha, Mina;Kwon, Ho-Jang
    • Journal of Preventive Medicine and Public Health
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    • v.50 no.6
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    • pp.377-385
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    • 2017
  • Objectives: Although mercury (Hg) exposure is known to be neurotoxic in humans, its effects on liver function have been less often reported. The aim of this study was to investigate whether total Hg exposure in Korean adults was associated with elevated serum levels of the liver enzymes aspartate aminotransferase (AST), alanine transaminase (ALT), and gamma-glutamyltransferase (GGT). Methods: We repeatedly examined the levels of total Hg and liver enzymes in the blood of 508 adults during 2010-2011 and 2014-2015. Cross-sectional associations between levels of blood Hg and liver enzymes were analyzed using a generalized linear model, and nonlinear relationships were analyzed using a generalized additive mixed model. Generalized estimating equations were applied to examine longitudinal associations, considering the correlations of individuals measured repeatedly. Results: GGT increased by 11.0% (95% confidence interval [CI], 4.5 to 18.0%) in women and 8.1% (95% CI, -0.5 to 17.4%) in men per doubling of Hg levels, but AST and ALT were not significantly associated with Hg in either men or women. In women who drank more than 2 or 3 times per week, AST, ALT, and GGT levels increased by 10.6% (95% CI, 4.2 to 17.5%), 7.7% (95% CI, 1.1 to 14.7%), and 37.5% (95% CI,15.2 to 64.3%) per doubling of Hg levels, respectively, showing an interaction between blood Hg levels and drinking. Conclusions: Hg exposure was associated with an elevated serum concentration of GGT. Especially in women who were frequent drinkers, AST, ALT, and GGT showed a significant increase, with a significant synergistic effect of Hg and alcohol consumption.

Generalized Linear Mixed Model for Multivariate Multilevel Binomial Data (다변량 다수준 이항자료에 대한 일반화선형혼합모형)

  • Lim, Hwa-Kyung;Song, Seuck-Heun;Song, Ju-Won;Cheon, Soo-Young
    • The Korean Journal of Applied Statistics
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    • v.21 no.6
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    • pp.923-932
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    • 2008
  • We are likely to face complex multivariate data which can be characterized by having a non-trivial correlation structure. For instance, omitted covariates may simultaneously affect more than one count in clustered data; hence, the modeling of the correlation structure is important for the efficiency of the estimator and the computation of correct standard errors, i.e., valid inference. A standard way to insert dependence among counts is to assume that they share some common unobservable variables. For this assumption, we fitted correlated random effect models considering multilevel model. Estimation was carried out by adopting the semiparametric approach through a finite mixture EM algorithm without parametric assumptions upon the random coefficients distribution.

A Study on the Management and Effect of Dysmenorrhea Care Program by Korean Traditional Medicine (한방 월경통 개선교실의 운영 및 효과에 관한 연구)

  • Jeong, Da-Un;Kim, Myung-Jae;Mo, Seung-Hee;Kim, Eun-Young;Lee, Kyoung-Sim;Park, Sung-Hee;Yu, Kyung-Soon
    • The Journal of Korean Obstetrics and Gynecology
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    • v.25 no.3
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    • pp.132-148
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    • 2012
  • Objectives: The aim of this study was to evaluate the effectiveness of dysmenorrhea care program by Korean traditional medicine on dysmenorrhiec juveniles. Methods: 47 adolescent dysmenorrhiec patients in local girls' high school took part in dysmenorrhea care program by Korean traditional medicine. The subjects were treated by acupuncture, ear-acupuncture, acupressure education, herbal extract medication and qigong exercise. The results were investigated by visual analogue scale(VAS), multidimensional verbal rating scale(MVRS) and verbal rating scale (VRS). Data was collected every three months from March, 2011 to March, 2012. Additionally satisfaction survey was conducted. Results: VAS score was reduced after treatment, but rebounded back to baseline after 6 months of discontinued dysmenorrhea care program. There was no significant difference of time and group interaction in linear mixed model analysis. MVRS and VRS outcomes showed similar pattern. Conclusions: Dysmenorrhea care program by Korean traditional medicine is effective in juveniles with dysmenorrhea for several months but not for long as nine months after treatment. However, the effect can last for three months at the very least.

Comparison of the bite force and occlusal contact area of the deviated and non-deviated sides after intraoral vertical ramus osteotomy in skeletal Class III patients with mandibular asymmetry: Two-year follow-up

  • Kwon, Hyejin;Park, Sun-Hyung;Jung, Hoi-In;Hwang, Woo-Chan;Choi, Yoon Jeong;Chung, Chooryung;Kim, Kyung-Ho
    • The korean journal of orthodontics
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    • v.52 no.3
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    • pp.172-181
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    • 2022
  • Objective: The objectives of this study were to compare the time-dependent changes in occlusal contact area (OCA) and bite force (BF) of the deviated and non-deviated sides in mandibular prognathic patients with mandibular asymmetry before and after orthognathic surgery and investigate the factors associated with the changes in OCA and BF on each side. Methods: The sample consisted of 67 patients (33 men and 34 women; age range 15-36 years) with facial asymmetry who underwent 2-jaw orthognathic surgery. OCA and BF were taken before presurgical orthodontic treatment, within 1 month before surgery, and 1 month, 3 months, 6 months, 1 year, and 2 years after surgery. OCA and BF were measured using the Dental Prescale System. Results: The OCA and BF decreased gradually before surgery and increased after surgery on both sides. The OCA and BF were significantly greater on the deviated side than on the non-deviated side before surgery, and there was no difference after surgery. According to the linear mixed-effect model, only the changes in the mandibular plane angle had a significant effect on BF (p < 0.05). Conclusions: There was a difference in the amount of the OCA and BF between the deviated and non-deviated sides before surgery. The change in mandibular plane angle affects the change, especially on the non-deviated side, during the observation period.

Perception of Korean Vowels by English and Mandarin Learners of Korean: Effects of Acoustic Similarity Between L1 and L2 Sounds and L2 Experience (영어권, 중국어권 학습자의 한국어 모음 지각 -모국어와 목표 언어 간의 음향 자질의 유사성과 한국어 경험의 효과 중심으로-)

  • Ryu, Na-Young
    • Journal of Korean language education
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    • v.29 no.1
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    • pp.1-23
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    • 2018
  • This paper investigates how adult Mandarin- and English- speaking learners of Korean perceive Korean vowels, with focus on the effect of the first language (L1) and the second language (L2) acoustic relationship, as well as the influence of Korean language experience. For this study, native Mandarin and Canadian English speakers who have learned Korean as a foreign language, as well as a control group of native Korean speakers, participated in two experiments. Experiment 1 was designed to examine acoustic similarities between Korean and English vowels, as well as Korean and Mandarin vowels to predict which Korean vowels are relatively easy, or difficult for L2 learners to perceive. The linear discriminant analysis (Klecka, 1980) based on their L1-L2 acoustic similarity predicted that L2 Mandarin learners would have perceptual difficulty rankings for Korean vowels as follows: (the easiest) /i, a, e/ >> /ɨ, ʌ, o, u/ (most difficult), whereas L2 English learners would have perceptual difficulty rankings for Korean vowels as follows: (the easiest) /i, a, e, ɨ, ʌ/ >> /o, u/ (most difficult). The goal of Experiment 2 was to test how accurately L2 Mandarin and English learners perceive Korean vowels /ɨ, ʌ, o, u/ which are considered to be difficult for L2 learners. The results of a mixed-effects logistic model revealed that English listeners showed higher identification accuracy for Korean vowels than Mandarin listeners, indicating that having a larger L1 vowel inventory than the L2 facilitates L2 vowel perception. However, both groups have the same ranking of Korean vowel perceptual difficulty: ɨ > ʌ > u > o. This finding indicates that adult learners of Korean can perceive the new vowel /ɨ/, which does not exist in their L1, more accurately than the vowel /o/, which is acoustically similar to vowels in their L1, suggesting that L2 learners are more likely to establish additional phonetic categories for new vowels. In terms of the influence of experience with L2, it was found that identification accuracy increases as Korean language experience rises. In other words, the more experienced English and Mandarin learners of Korean are, the more likely they are to have better identification accuracy in Korean vowels than less experienced learners of Korean. Moreover, there is no interaction between L1 background and L2 experience, showing that identification accuracy of Korean vowels is higher as Korean language experience increases regardless of their L1 background. Overall, these findings of the two experiments demonstrated that acoustic similarity between L1 and L2 sounds using the LDA model can partially predict perceptual difficulty in L2 acquisition, indicating that other factors such as perceptual similarity between L1 and L2, the merge of Korean /o/ and /u/ may also influence their Korean vowel perception.

BMDL of blood lead for ADHD based on two longitudinal data sets (주의력 결핍 과잉 행동장애를 종점으로 하는 혈중 납의 벤치마크 용량 하한 도출: 두 동집단 자료의 병합)

  • Kim, Si Yeon;Ha, Mina;Kwon, Hojang;Kim, Byung Soo
    • The Korean Journal of Applied Statistics
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    • v.31 no.1
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    • pp.13-28
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    • 2018
  • The ministry of Environment of Korea initiated two follow-up surveys in 2005 and 2006 to investigate environmental effect on children's health. These two cohorts, referred to as the 2005 Cohort and 2006 Cohort, were followed up three times every two years. This data set was referred to as the Children's Health and Environmental Research (CHEER) data set. This paper reproduces the existing research results of Kim et al. (Journal of the Korean Data and Information Science Society, 25, 987-998, 2014) and Lee et al. (The Korean Journal of Applied Statistics, 29, 1295-1310, 2016) and derive a benchmark dose lower limit (BMDL) for blood lead level for attention deficit hyperactivity disorder (ADHD) after pooling two cohort data sets. The different ADHD rating scales were unified by applying the conversion formula proposed by Lee et al. (2016). The random effect model and AR(1) model were built to reflect the longitudinal characteristics and regression to the mean phenomenon. Based on these models the BMDLs for blood lead levels were derived using the BMDL formula and the simulation. We obtained a hight level of BMDLs when we pooled two independent cohort data sets.

Association of genetic polymorphism in fatty acid synthase with BodyFat and fatty acid composition in Hanwoo (한우 FASN 유전자변이와 한우 지방형질 및 지방산조성과의 연관성 분석)

  • Lee, Seung-Hwan;Kim, Hyeong-Cheol;Cho, Won-Mo;Chang, Sun-Sik;Kim, Bum-Soo;Chang, Gul-Won;Lee, Jun-Hun;Yeon, Seong-Heum;Hong, Seong-Koo
    • Korean Journal of Agricultural Science
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    • v.38 no.2
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    • pp.257-262
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    • 2011
  • The aim of this study was to identify the polymorphism on fatty acid synthase (FASN) gene and its association with fat traits and fatty acid composition in Hanwoo. We genotyped a SNP (g.16024G${\rightarrow}$A) detected in Exon34 of FASN on 90 Hanwoo steers by PCR RFLP. A linear mixed model revealed an association of g.16024G${\rightarrow}$A with total body fat contents (P=0.006), while there is no significant effect between g.16024G${\rightarrow}$A and other traits (IMF, BF and fatty acid composition). Regression coefficient and $R^2$ of the SNP was -1.5 kg and 0.36 in this anslysis. Expecially, AA type of g.16024G${\rightarrow}$A bas a less amount of body fat (1.5 kg) than GG type of the SNP in Hanwoo. In conclusion, this study indicates an important role for FASN gene in determining body fat content in Hanwoo.

Association of a missense mutation in the positional candidate gene glutamate receptor-interacting protein 1 with backfat thickness traits in pigs

  • Lee, Jae-Bong;Park, Hee-Bok;Yoo, Chae-Kyoung;Kim, Hee-Sung;Cho, In-Cheol;Lim, Hyun-Tae
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.8
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    • pp.1081-1085
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    • 2017
  • Objective: Previously, we reported quantitative trait loci (QTLs) affecting backfat thickness (BFT) traits on pig chromosome 5 (SW1482-SW963) in an F2 intercross population between Landrace and Korean native pigs. The aim of this study was to evaluate glutamate receptor-interacting protein 1 (GRIP1) as a positional candidate gene underlying the QTL affecting BFT traits. Methods: Genotype and phenotype analyses were performed using the 1,105 $F_2$ progeny. A mixed-effect linear model was used to access association between these single nucleotide polymorphism (SNP) markers and the BFT traits in the $F_2$ intercross population. Results: Highly significant associations of two informative SNPs (c.2442 T>C, c.3316 C>G [R1106G]) in GRIP1 with BFT traits were detected. In addition, the two SNPs were used to construct haplotypes that were also highly associated with the BFT traits. Conclusion: The SNPs and haplotypes of the GRIP1 gene determined in this study can contribute to understand the genetic structure of BFT traits in pigs.