• Journal of Ginseng Research
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• 제15권2호
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• pp.117-119
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• 1991

In continuation of previous isolation of two lignan components, Gomisin A and -N, from Korean Red Ginseng the presence of the two lignans was identified in the hexane extract of Korean White Ginseng by gas chromatographic analysis.

• Natural Product Sciences
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• 제4권4호
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• pp.238-240
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• 1998

A new lignan, gossypiline (1) has been isolated from the aerial parts of Jatropha gossypifolia. The structure of 1 was established from its spectral data. The conversion of isogadain, a known lignan, to 1 confirmed the structure as well as the stereochemistry of 1.

• 한국작물학회지
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• 제48권
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• pp.65-71
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• 2003

Sesame seed are one of the oldest oil-bearing crops known to man. Not only are they nutritious, they are physicologically beneficial. Because of these properties, the promotion of sesame as a crop is set to increase from now on. The lignan component of sesame, which has an antioxidative function, varies considerably. In addition, the seeds remain viable for longer than other crops. At low temperature, it has been reported that the seed remain viable for up to thirty years. This is due to the lignan content of the seeds. In the last twenty years, the mysteries of the natural chemistry of sesame seeds have been unravelled one by one. Up to now, the lignan component has been found to have an $\alpha$-tocopherol synergist effect, an anti-aging effect, a cancer suppressing effect, a hypertension reduction effect, an effect on the promotion of liver function, an effect on the control of the ration of unsaturated fat, and an effect on the synthesis of unsaturated fatty acids. The lignan component of sesame does not simply have an anti-oxidant function, but has diverse recently discovered physiological uses which make the study of lignan highly rewarding.

• Archives of Pharmacal Research
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• 제29권12호
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• pp.1109-1113
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• 2006

A new furofuran lignan, 4-hydroxykobusin (3), together with known lignans, kobusin (1), and 7,7'-dihydroxybursherenin (2), were isolated from the whole plant of Geranium thunbergii Sieb. et Zucc (Geraniaceae). The structures were determined based on the spectral data and a comparison with the published data. This is the first report of the presence of furofuran lignan in Geranium species.

• 한국유기농업학회지
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• 제24권4호
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• pp.893-905
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• 2016

본 연구에서는 팽화처리 된 오미자의 lignan 성분 함량과 항산화 활성 평가를 통해 가공에 따른 품질 특성을 비교하고자 하였다. 팽화오미자의 lignan 성분 함량은 대조구에 비해 모두 증가하였고, $5kgf/cm^2$의 압력에서는 다소 감소하는 경향을 보였다. 항산화 활성 또한 오미자를 팽화처리 하였을 때 총 폴리페놀 함량과 플라보노이드 함량은 대조구에 비해 모두 증가하였고, 압력이 높아질수록 함량이 증가하다가 $5kgf/cm^2$의 압력에서는 다시 감소하였으며 DPPH radical, ABTS radical 소거능에서도 유사한 경향을 보였다. 이는 팽화 처리에 의한 추출수율의 증가 및 약리성분이 변화됨으로써 생리활성 변화에 기인한 것으로 판단되어지며 어느 일정 압력의 이상으로 처리할 경우 오히려 lignan 성분 함량과 항산화 활성이 감소하는 것을 확인할 수 있었다. 따라서, 오미자를 팽화처리 하였을 때 lignan 성분 함량이 증가하였으며 항산화 활성 또한 대조구에 비해 증가하였고 $3kgf/cm^2$의 압력으로 처리하였을 때 가장 효과적이었다.

• 한국작물학회:학술대회논문집
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• 한국작물학회 1992년도 춘계 학술대회지
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• pp.132-133
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• 1992

• 약학회지
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• 제21권2호
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• pp.81-86
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• 1977

A lignan glycoside, mp 263-$5^{\circ}$, $C_{34}H_{46}O_{18}$, was isolated from the cortex of Acanthopanax sessiliflorum forma chungbunensis C.S.Yook and it was identified as lirioresinol ${\beta}$-diglucoside, liriodendrin. The compound stimulated the incorporation of $^{14}$C-leucine into mouse liver protein.

• Archives of Pharmacal Research
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• 제13권3호
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• pp.289-291
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• 1990

A lignan (+) isolariciresinol, was isolated from Rubia akane Nakai. This is the first reporting form Rubiaceae.

• Applied Biological Chemistry
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• 제32권4호
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• pp.350-356
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• 1989

무주산 오미자로부터 lignan 화합물인 deoxyschizandrin, gomisin N, schizandrin, gomisin A, wuweizisu C, angeloygomisin H 및 tigloylgomisin H를 분리 동정하고 capillary-GC (FID)를 이용하여 이들 화합물의 정량성을 조사하였다. 이 때 lignan 화합물의 동정에는 GC/MS (Finigan MAT 212; El, 70eV), 1H-NMR (Bruker FT; 300MHz) 및 IR (Perkin Elmer 599B)을 이용하였으며, lignan 화합물의 정량에는 FID 및 integrator(Hewlett-Packard 3393A)가 부착된 GC (Hewlett-Packard 5890A)를 이용하였다. 한편, GC column은 SPB-1 fused silica capillary$(0.25mm\;ID{\times}30m,\;Supelco)$를 사용하였고 column oven의 온도는 $200^{\circ}C$부터 $300^{\circ}C$까지 분당 $4^{\circ}C$씩 승온하였으며, carrier gas는 $N_2$, 1.0ml/min(split ratio=40 : 1)을 사용하였다. 각 lignan 화합물의 정량 가능농도범위는 deoxyschizandrin과 wuweizisu C가 $2{\sim}500ppm$이었고 gomisin N, schizandrin, gomisin A, angeloylgomisin H 및 tigloygomisin H 가 $5{\sim}500ppm$이었으며 무주산 오미자의 lignan성분 함량은 schizandrin이 6.50mg/g으로 가장 높았고 gomisin N, gomisin A, wuweizisu C, angeloylgomisin H, deoxyschizandrin, tigloylgomisin H의 순으로 낮은 경향이었다.

• Food Science and Biotechnology
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• 제16권6호
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• pp.981-987
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• 2007

Effects of lignan compounds (sesamol, sesamin, and sesamolin) extracted from roasted sesame oil on the autoxidation at $60^{\circ}C$ for 7 days and thermal oxidation at $180^{\circ}C$ for 10 hr of sunflower oil were studied by determining conjugated dienoic acid (CDA) contents, p-anisidine values (PAV), and fatty acid composition. Contents of lignan compounds during the oxidations were also monitored. ${\alpha}$-Tocopherol was used as a reference antioxidant. Addition of lignan compounds decreased CDA contents and PAY of the oils during oxidation at $60^{\circ}C$ or heating at $180^{\circ}C$, which indicated that sesame oil lignans lowered the autoxidation and thermal oxidation of sunflower oil. Sesamol was the most effective in decreasing CDA formation and hydroperoxide decomposition in the auto- and thermo-oxidation of oil, and its antioxidant activity was significantly higher than that of ${\alpha}$-tocopherol. Sesamol, sesamin, and sesamolin added to sunflower oil were degraded during the oxidations of oils, with the fastest degradation of sesamol. Degradation of sesamin and sesamolin during the oxidations of the oil were lower than that of ${\alpha}$-tocopherol. The results strongly indicate that the oxidative stability of sunflower oil can be improved by the addition of sesamol, sesamin, or sesamolin extracted from roasted sesame oil.