• Title/Summary/Keyword: life-time use

Search Result 1,785, Processing Time 0.037 seconds

P-Selectin-mediated Acute Inflammation Can Be Blocked by Chemically Modified Heparin, RO-Heparin

  • Gao, Yanguang;Li, Na;Fei, Rui;Chen, Zhihong;Zheng, Sheng;Zeng, Xianlu
    • Molecules and Cells
    • /
    • v.19 no.3
    • /
    • pp.350-355
    • /
    • 2005
  • Selectins are carbohydrate-binding cell adhesion molecules that play a major role in the initiation of inflammatory responses. Heparin can bind to P-selectin, and its anti-inflammatory property is mainly due to inhibition of P-selectin. However, the strong anticoagulant activity of heparin limits its clinical use. We prepared periodate-oxidized, borohydride-reduced heparin (RO-heparin) by chemical modification and tested its anticoagulant and anti-inflammatory activities. Activated partial thromboplastin time (aPTT) assays showed that, compared with heparin, RO-heparin had greatly reduced anticoagulant activity. Intravenous administration of this compound led to reduction in the peritoneal infiltration of neutrophils in a mouse acute inflammation model. In vitro cell adhesion experiments demonstrated that the effect of RO-heparin on inflammatory responses was mainly due to inhibiting the interaction of P-selectin with its ligands. These results indicate that RO-heparin may be a safer treatment for inflammation than heparin, especially when selectin is targeted.

Strengthening Performance of Aged Papers with Chemical Strengthening Treatments (화학적 보강 방법에 따른 열화 종이의 보강 특성)

  • Lee, Hyeyoon;Lee, Jegon;Kim, Minsu;Sim, Kyujeong;Youn, Hye Jung
    • Journal of Korea Technical Association of The Pulp and Paper Industry
    • /
    • v.46 no.5
    • /
    • pp.35-42
    • /
    • 2014
  • Many historical archives have been deteriorated by aging with time. Various kinds of defects such as worm-hole, yellowing, brittleness are observed and their severity was dependent on raw material type, storage condition, and so on. For a long-term use and storage, a proper preservation treatment is required. Many studies on preservation and conservation have been carried out on hanji which was made from mulberry fiber, but there are few concerns on foreign paper. Therefore, aging and chemical strengthening treatment was done on paper made of bamboo and wood fibers depending on aging condition, the type and pickup weight of chemicals and treatment method. When methyl cellulose was treated with impregnation or brushing, the aged paper was strengthened effectively. The strengthening effect by chemicals was dependent on the aged condition of the paper.

Medium Optimization for the Production of Probiotic Lactobacillus acidophilus A12 Using Response Surface Methodology

  • Lee, Na-Kyoung;Park, Yeo-Lang;Choe, Ga-Jin;Chang, Hyo-Ihl;Paik, Hyun-Dong
    • Food Science of Animal Resources
    • /
    • v.30 no.3
    • /
    • pp.359-364
    • /
    • 2010
  • Lactobacillus acidophilus A12 was isolated from chicken feces for use as an immunostimulating livestock probiotic. The purpose of this study was to optimize the production of L. acidophilus A12 using response surface methodology (RSM). Initially, the influence of growth medium was studied in terms of carbon sources (glucose, fructose, lactose, glycerol, sucrose, ethanol, and mannitol), nitrogen sources (beef extract, yeast extract, malt extract, and tryptone), and inorganic salts ($CaCl_2$, $MgSO_4$, $KH_2PO_4$, $(NH_4)_2SO_4$, $FeSO_4$, and NaCl). Through one factor-at-a time experiment, lactose, yeast extract, and $CaCl_2$ were determined to be the best sources of carbon, nitrogen, and inorganic salt, respectively. The optimum composition was found to be 17.7 g/L lactose, 18.6 g/L yeast extract, and 0.9 g/L $CaCl_2$. Under these conditions, a maximum cell density of 9.33 Log CFU/mL was produced, similar to the predicted value.

The Effects of Life Stress on University Life Satisfaction and Major Satisfaction Convergence Era. (융복합시대에 생활스트레스가 대학생활만족도와 전공만족도에 미치는 영향)

  • Lee, Jae-Ra;Kim, Seo-Yeon
    • Journal of Convergence for Information Technology
    • /
    • v.8 no.6
    • /
    • pp.21-29
    • /
    • 2018
  • The purpose of study is to investigate the effect of life stress on university life satisfaction and majors' From April 2, 2018 to April 23, 2018, 364 students enrolled in Jeollanam-do and Gwangju were enrolled. The university life satisfaction and major satisfaction according to the general characteristics were the highest in the subjective health condition. Among the stresses of life, the professions were high in the interpersonal relations area and the academic problems were the highest among the task areas. The total stress of life was the lowest in 6-8 hours in the case of usual sleeping time. The major factor influencing college life satisfaction was majors' satisfaction. The major factor influencing major satisfaction was college life satisfaction, and the higher the life stress, the lower the satisfaction of major. Therefore, I would like to use this data as basic data for the development of programs that can alleviate life stress of University students.

Single Phase Switched Reluctance Motor for Vacuum Cleaner (진공청소기용 단상 스위치드 리럭턴스 모터)

  • Lim, Jun-Young;Jung, Yun-Chul;Kim, Sang-Young;Choi, Yong-Won;Kim, Jungn-Chul
    • Proceedings of the KIPE Conference
    • /
    • 2001.07a
    • /
    • pp.247-251
    • /
    • 2001
  • Universal motors are mainly used for vacuum cleaner application. There are a lot of researches on SRM that applys home appliance throughout the world. The manufacturing cost of SRM drive makes it hard to expand its application to home appliance. This paper presents Single Phase SRM for the vacuum cleaner that has advantge in cost and performance over conventional universal motor. This paper proposes new power device driving scheme by using SRM switching characteristic. The driving scheme is very simple and inexpensive. Dwell Time Control method is used for the minimum switching loss of power device. The switching frequency of power device is less than 4.5kHz at 45,000rpm. By use of this scheme, power device based on very small switching losses can be used on SRM drive. Also, the biggest problem in single phase SRM is starting, this paper shows a new starting algorithm with two hall sensors, accelerating and running sensors, respectively. Finally, the proposed Single Phase SRM achieves higher efficiency and long life time compared to universal motor. Its life time is more than 1500 hours. Its life time is extended 4 times than that of conventional motor and its suction power is increased $20\%$ at the same volume of conventional universal motor.

  • PDF

The Effect of Paraffin Treatment with Exercise on Muscle Strength and Fatigue of the Hand According to the Use of Smartphone

  • Kim, Su-Hyon
    • The Journal of Korean Physical Therapy
    • /
    • v.32 no.4
    • /
    • pp.198-202
    • /
    • 2020
  • Purpose: This study examined the effects of a paraffin treatment with exercise on the muscle strength and fatigue of the hand according to the use of smartphones. Methods: The measurement subjects were 30 healthy males in their 20s who were divided randomly into the control and paraffin treatment groups. A typing exercise using a smartphone was performed. The pinch grip force was measured to evaluate the muscle strength of the thumb, and muscle fatigue analysis using electromyography was performed to analyze muscle fatigue. Results: The functional changes to the arm and the fatigue of the hand through the use of a smartphone were examined to determine the effects of the paraffin treatment. The dominant hand-pinch grip force test did not show a significant difference, but the non-dominant hand-pinch grip force test showed a significant difference between the groups (p=0.030). In the dominant hand fatigue test, there was a significant difference between the groups (p=0.037). In the non-dominant hand, there was a significant difference between time (p=0.012) and the groups (p<0.001). Conclusion: The effects of paraffin intervention on the hand muscle strength and fatigue due to repeated use of the smartphone were confirmed. These results can be used as a basis for clinical use and can be a guide for the correct use of smartphones, which are essential in modern life.

Consumer Awareness, Use, and Satisfaction of Nutrition Labeling at Bakery and Ice-cream Stores in Daejeon (대전지역 베이커리와 아이스크림 전문점의 영양표시에 대한 소비자의 인지, 활용 및 만족도)

  • Choi, Myeong;Lee, Joung-Won
    • Journal of the Korean Society of Food Culture
    • /
    • v.26 no.5
    • /
    • pp.417-428
    • /
    • 2011
  • To promote use of nutrition labels, degrees of awareness, use, and satisfaction of nutrition labeling on eating-out menus were investigated by a self-recorded questionnaire from May to July 2010 in 629 participants who visited four bakery chains (n=409) and three ice-cream chains (n=220) located in Daejeon. Of the subjects 53.4% were female, 68.8% aged 20~29 years, and 59.3% visited bakery or ice-cream stores 1~3 times per month. Only 38.2% of participants had knowledge of nutrition-labeling mandates for eating-out menus, and 74.9% had seen labels before in bakery and ice-cream stores. Most subjects understood calorie amount and daily value of sodium very well, but they failed to understand the meaning of daily value. Only 21.2% of the subjects understood nutrition label information completely. Of the participants, 46.7% read nutrition labels in bakery or ice-cream stores when purchasing. Among the subjects who read the labels, 77.2% (36.1% of total subjects) referred to the label information when selecting a menu and 46.9% (21.9% of total subjects) had experienced altering their menu choice based on the information. Exactly 53.3% of subjects answered they did not read nutrition labels since they were not interested or had no time, or because the labels were not noticeable. Satisfaction of the place, timing, and format of nutrition labels at bakery and ice-cream stores fell below average overall. Many subjects wanted trans fat and cholesterol to be added to the labels. In conclusion, degrees of perception, use, and satisfaction of nutrition labels at bakery and ice-cream stores were still low. More effective publicity and consumer education about nutrition labeling will be necessary, and bakery or ice-cream companies should make efforts to improve nutrition labeling such as providing format and place.

Online Food Delivery App Distribution and Determinants of Jakarta's Gen Z Spending Habits

  • INDRIYARTI, Eko Retno;CHRISTIAN, Michael;YULITA, Henilia;RUMINDA, Marthaleina;SUNARNO, Sunarno;WIBOWO, Suryo
    • Journal of Distribution Science
    • /
    • v.20 no.7
    • /
    • pp.73-86
    • /
    • 2022
  • Purpose: Considering the COVID-19 pandemic and the increasing number of online food delivery applications (OFDA), this study aims to assess the distribution of the presence of Indonesian OFDA and to measure the factors that influence the spending habits of OFDA users. Research design, data and methodology: Two hundred and nine OFDA users from Jakarta's Generation Z were surveyed via a questionnaire. The data were analyzed using Structural Equation Modeling and SMART PLS 3.0. Results: OFDAs were introduced into Indonesia in the recent past with varying degrees of popularity determined by the number of downloads. Users' intention to use was not determined by the speed of the introduction of an OFDA. This study also reveals that previous experience of the service, the orientation of time and price savings had a significant effect on spending habits. A moderating role of the saving variable on time and price was not demonstrated. Conclusions: The results of the study suggest that, in COVID-19 pandemic conditions, the spending habits of Generation Z are not based on impulse, thrift, or extravagance. The pandemic shaped specific motivations in spending habits, namely prioritizing need. This study has limitations, including the small sample size and the use of internal variables.

Time Allocation of Farm wives:A Household Production Approach (농가주부의 시간배분연구: 가정생산이론적 접근)

  • 김인숙
    • Journal of Families and Better Life
    • /
    • v.14 no.3
    • /
    • pp.181-196
    • /
    • 1996
  • This study examined the time allocation pattern of farm wives. In particular it addressed i)the differences in extent of time spent in farming housework child care and leisure between on-farm and off-farm seasons ii)differences in the extent of time spent in such activities among farm wives and urban wives and iii) the determinants of time spent in such activities. To achieve these goals a system of time allocation equations based on household production theory was employed. On hundred and eight farm wives wiere selected in 1993 by the methods of judgement sampling and cluster sampling. Two major questions in the survey elicited sociodemographic information and time-use of farm wives using the time-diary method, The results indicate that farm wives different decisions about how to allocate their time to farming housework child care leisure during on-farm and off-farm seasons. In addition it was that farm wives are more likely to have dual responsibilities than are urban wives. Finally in the off-farm season education number of younger children and region were significant variables in explaining the time allocation decisions of farm wives. However only age was a significant factor in their time allocation decisions during the on-farm season. This leads one to conclude that time allocation is not a choice for farm wives in the on-farm season.

  • PDF

A survey on sex life behavior and factors of low back pain (요통환자들의 성생활 행태와 영향 요인 조사)

  • Nam, Chul-Hyun;Woo, Kwang-Seog
    • Journal of Korean Physical Therapy Science
    • /
    • v.9 no.3
    • /
    • pp.31-49
    • /
    • 2002
  • The purpose of this study was to investigate discomforts and sexual life and to identify the relation between the discomforts and sexual life with low back pain. The data were collected from March 2 through July 31, 2001. Four hundred forty-two questionnaires were returned (response rate=88.0%). Analysis of the data was done with SPSS PC+ and use descriptive statistics, $x^2$-test, t-test, ANOVA. regression. The statistics shows that over than 80% of the adults experienced lumbago at least one time in their life, and Back pain is known as one of the most common complaints made by the patients of all ages in the general hospital or local medical clinics throughout. However, in certain case it leads to a chronic condition which can cause a great deal of problems in management and in financial burden to individuals and society. The result of this study was summarized as follows: 1) It appeared that regarding the distribution of gender, male was the higher(63.6%) then that of female, the portion of forties was 28.5%. Sitting for long time was 23.1% in men and 21.7% in women. Unknown reason including sexual behaviour was 12.9% in men and 15.5% in women. Patients treated medicine and physical therapy were 36.4%. In level of educational background, the rate of high school was 31.0%, technical college was 28.5%. The highest proportion by occupation was 18.3% of office workers, occupation posture was 41.9% of sitting. 2) Men(26.0%) and most of women(34.8%) were not satisfied in the explanation satisfaction rate of sex life concerned disease. 23.8% in men and 23.6% in women considered flexibility of waist good. Man(33.3%) and most of woman(35.0%) considered that Health education is necessary. 32.7% in men and 27.3% in women did't mind educator is whoever. Preventing of lower back pain(LBP) and proper Health education of sex life are demanded in daily life. 3) 58.0% of man and 64.0% of woman mostly had a posture which is man over woman. 28.5% in men and 27.8% in women considered that proper information finding of LBP and sex life was very few and few. 37.7% in men and 42.7% in women have acquired information about sex life flung their friends. 4) The number of sex life was decreased from 2.96 0.98 to 2.61 1.63 and also the time of sex life was decreased from 3.65 1.89 to 226 1.64. The satisfaction rate of sex life changed from 3.60 0.86 to 2.77 1.10. In the number of sex life, The non correct group was 2.62 1.91 and the correct group was higher in 2.68 1.65. In the time of sex life, The non correct group was 2.02 1.47 and the correct group was higher in 229 1.65. The satisfaction rate of sex life was 2.76 0.86 in non correct group and 2.88 1.10 in correct group. So there was a difference. 5) In the satisfaction rate of sex life, Men who have a lower back pain were higher than women and no attack group was higher than attack group. As they had many sex life, the satisfaction rate was higher significantly in statistics. As the time of sex life was short, the satisfaction rate was lower significantly in statistics. As the age was low, the demand rate of Health education was high and as means of patient who had a lower back pain was high, the demand rate of Health education was high. As the patient who had a lower back pain had a long married life, the demand rate of Health education was high and as education level was high, the demand rate of Health education was high. It is necessary to provide patients with conservative treatment, educational teaching, and training to prevent further injuries in the future. In general, it is important to educate the public how to prevent back injuries and how to treat themselves in an onset period to prevent further injuries sliding into a chronic state. Sexuality is an integral part of normal and healthy relationships, but patients are unable to enjoy sex because they are riot able to get into a comfortable position due to back pain. Many conditions of the spine can make certain positions uncomfortable. Health educator should make the education program of the discomforts and the sexual pattern for low back pain in workplace and/or hospital. Further study Is needed on how to integrate the educational program on sexuality into the total rehabilitation program.

  • PDF