• Title/Summary/Keyword: left kidney

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Spontaneous Hydronephrosis in $C57BL/KsJ-Lepr^{db}/Lepr^{db}$ Mouse, an animal Model for Human NIDDM (인슐린비의존형 당뇨병 마우스 $C57BL/KsJ-Lepr^{db}/Lepr^{db}$ 의 수신증 발생 예)

  • Jeong, Su-Yeon;Yun, Young-Min;Seong, Je-Kyung
    • Korean Journal of Veterinary Pathology
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    • v.3 no.2
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    • pp.93-94
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    • 1999
  • Spontaneous hydronephrosis was found in a 19 month-old female C57BL/KsJ-Lep $r^{db}$ / Lep $r^{db}$ mouse. We described the gross and histological appearance of spontaneous in db mouse The left kidney was dilated and filled with urine. Microscopically the renal pelvis was remarkedly dilated and the renal cortex and renal papilla were flattened.

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Spontaneous nephroblastoma in a New Zealand White rabbit : A case report (New Zealand White 토끼의 신아세포종(Nephroblastoma) 자연발생례)

  • Kang, Booh-yon;Ha, Cbang-su
    • Korean Journal of Veterinary Research
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    • v.32 no.1
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    • pp.111-115
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    • 1992
  • A round, milkish white mass, approximately $4{\times}4{\times}5cm$ in size was found at the cranial part of the left kidney from a New Zealand White rabbit which was used as an untreated control animal in the safety evaluation test in the Toxicology Research Center, Korea Research Institute of Chemical Technology. The mass was lobulated and encapsulated. The cut surface revealed several round well-circumscribed lobules which were 0.5-3cm in diameter. No metastasis was observed. The microscopic features consisted of blastema and epithelial structures at variable stages of differentiation including primitive tubules, ducts, glomeruloid bodies. Normal mesenchymal cells were distributed among them. A diagnosis of nephroblastoma was made on the basis of the gross and microscopic features.

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Nutcracker syndrome combined with immunoglobulin A nephropathy: two case reports

  • So Hyun Ki;Min Hwa Son;Eujin Park;Hyung Eun Yim
    • Childhood Kidney Diseases
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    • v.27 no.2
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    • pp.133-138
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    • 2023
  • Nutcracker syndrome (NCS) is a disease caused by compression of the left renal vein between the superior mesenteric artery and the abdominal aorta. Immunoglobulin A (IgA) nephropathy (IgAN) is characterized by the predominance of IgA deposits in the glomerular mesangial area. Hematuria and proteinuria can be present in both diseases, and some patients can be concurrently diagnosed with NCS and IgAN; however, a causal relationship between the two diseases has not yet been clarified. Here, we report two pediatric cases of NCS combined with IgAN. The first patient presenting with microscopic hematuria and proteinuria was diagnosed with NCS at the initial visit, and the second patient was later diagnosed with NCS when proteinuria worsened. Both patients were diagnosed with IgAN based on kidney biopsy findings and treated with angiotensin-converting enzyme inhibitors and immunosuppressants. A high index of suspicion and timely imaging or biopsy are essential for the proper management of NCS combined with glomerulopathy.

Regional Differences of Entry Rate of Freely Diffusible Substances from Peritoneal Cavity (복강내 확산성 물질의 부위별 흡수속도)

  • Cho, Byeong-Deuck;Shin, Dong-Hoon
    • The Korean Journal of Physiology
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    • v.1 no.2
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    • pp.157-168
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    • 1967
  • The entry of antipyrine and urea from the peritoneal cavity of rabbit into organ tissue and blood plasma was studied. Two hundred mg of antipyrine plus 300 mg of urea in 10 ml Ringer's solution was injected into the peritoneal cavity of anesthetized rabbit. The injection was made from above of a rabbit kept tying right side down and it enabled part of the abdominal organs (liver, intestine, kidney) was immersed in the injected solution and kept high concentration gradient throughout the experimental period. The remaining part of the organs was revered only by a thin film of the test solution. Subsequently, in this part of the organs the concentration gradient of the diffusible substances during entry was presumed to decrease as time elapsed. Four pieces of the liver tissue were taken namely, the right superficial, right deep, left superficial and left deep portions. Two were taken from the small intestine, one from the portion which was immersed in. the fluid and the other from that above the fluid mass. Both kidneys were separately analyzed. As a remote organ the gastrocnemius muscle was taken from the right leg of the animal. The intervals which were the time periods elapsed after injections were 5,7,10,15 or 30 minutes. At each point 5 animals were sacrificed and the concentrations of the test substances in the tissue water were measured. The results obtained were as follows. 1. In the liver the right portion which was immersed in the fluid showed higher concentration if the test substances than the left portion and the superficial region exceeded the deep region. The concentrations diminished as the time elapsed after infusion, particulary in the case of antipyrine, suggesting circulatory removal of the substances. In urea such decreasing tendency of the concentration was not obvious, and suggested slower removal rate of it as compared with that of antipyrine. 2. In the small intestine there was no regional difference in the concentration of the test substances. Because of the intestinal motility different portions of the intestine were seemed to have bathed in the fluid of the same concentration. In general the concentrations in the intestinal wall exceeded those of the liver, suggesting a slower removal rate than in the latter. 3. In the kidney the accumulation of the endogenous urea was predominant, and the accumulating mechanism in the renal tissue went on during the period of the experiment. Therefore it revealed increasing tendencies as the time elapsed. The penetration of the test substances in this organ from the peritoneal cavity seemed to be slower than in other abdominal organs, namely liver or small intestine. Part of the test substances in the kidney were obviously brought by the blood stream. 4. Rapid exponential decay of the concentration of antipyrine and of the osmolality of the peritoneal fluid was attributed to the extensive removal through the whole dimension of the peritoneal surface, and the remote organ such as the gastrocnemius muscle attained a fairly close value to that of the abdominal organs in less than 30 minutes. The factors which related to the absorption rate were discussed. They were the concentration gradient, permeability and the regional perfusion rate.

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Latest Study on the Assignment of the Eight Trigrams in Human Body (팔괘(八卦)의 인체 배속(配屬)에 대한 새로운 연구 - (하도 락서)河圖 洛書를 중심으로-)

  • Shin, Soon-Shik;Kim, Hun;Kim, Yi-Soon;Kim, Gyeon-Cheol
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.20 no.6
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    • pp.1447-1450
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    • 2006
  • To study on the assignment of the eight trigrams (八卦) in human body being based on based the number of HADO(河圖)-NAGSEO(洛書). Being based on the number of HADO(河圖)-NAGSEO(洛書) and the BEOK-HEE's diagram of eight trigrams order(伏羲次序圖), human being organ (five-Jang organs (liver, heart, spleen, lung and kidney), five organs (ear, eye, mouth and nose), provisional namely six entera for the process on intake, digestion, excretion of food (mouth, stomach, small intestine, large intestine, rectum, anus) are assigned eight trigrams (八卦). Eight trigrams(八卦) are attached to the based on the number HADO(河圖)-NAGSEO(洛書): 1-GEON(乾), 2-TAE(兌), 3-LEE(離), 4-JIN(震), 9-SON(巽), 6-GAM(坎), 7-GAN(艮), 8-GON(坤). And (八卦) are attached to the human being organs (five-Jang organs (live, heart, spleen, lung and kidney), five organs (ear, eye, mouth, nose, anus) : 1-GEON(乾)-left lung-left nose, 6-GAM(坎)-right kidney-right ear, 7-GAN(艮)-left heart-anus, 8-GON(坤)-right liver-right ear. Eight trigrams(八卦) are attached to the provisional namely six entera for the process on intake, digestion, excretion of food : the air(GEON 乾), the month(TAE 兌), the stomach(LEE 離), the small intestine(JIN 震), the large intestine(Son 巽), the rectum(GAM 坎), the anus(GAN 艮), the excrements(GON 坤). The BEOK-HEE's diagram of eight trigrams order(伏羲次序圖) means immutable order naturally. The process of the human being organs( five-Jang organs, five organs and six entera's digestion) is also unchangeable in region and program. Therefore we can set up the five-Jang organs, five organs and the process of six entera's digestion as the category of observation on the basis of BEOK-HEE's diagram of eight trigrams order(伏羲次序圖), and then we can arrange eight trigrams (八卦) on the five-Jang organs, five organs and the process of six entera's digestion.

Discrepancy and Correlation in the renal length between Kidney CT and 99mTc-DMSA Renal scan (신장 CT 검사와 99mTc-DMSA Renal Scan 검사에서 측정한 신장 길이의 차이 및 상관분석)

  • Jung, Woo-Young;Shim, Dong-Oh;Lee, Dong-Hun;Choi, Jae-Min
    • The Korean Journal of Nuclear Medicine Technology
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    • v.25 no.1
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    • pp.15-20
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    • 2021
  • Purpose This article studies the relationship between the length of a kidney measured by two scanning methods: Kidney Computed Tomography (CT) and 99mTc-Dimercaptosuccinic acid (DMSA) renal scan. Kidney CT provides a better anatomic assessment, while 99mTc-DMSA renal scan is superior in the kidney function test. Materials and Methods From January to December of 2019, two hundred patients who had Kidney CT and Tc99m-DMSA renal scan were chosen for this study. SPSS17.0 was selected for statistical analysis. Results Due to the effect of the breathing and resolution of 99mTc-DMSA renal scan, it showed the kidney's relatively longer length than the length of Kidney CT. For the same kidney, the length comparison among different brands' Gamma cameras was negligible. The length difference within the same age group did not show a noticeable discrepancy. However, there was a length difference between the radio technologists. Kidney CT and 99mTc-DMSA renal scan indicated a strong positive correlation between the length of the left and right kidney. Conclusion It is necessary to establish a standardized measurement method for measuring kidney length using 99mTc-DMSA renal scan. The kidney's functional changes and length changes are indications of Kidney diseases. Especially, pediatric patients tend to use 99mTc-DMSA renal scan for assessing the kidney's shape and the function to avoid potential radiation exposure during the Kidney CT. Therefore, it is significant to provide not only the kidney's functional information but also an anatomic analysis, including the kidney's size, length, and location through the 99mTc-DMSA renal scan.

Incidentally detected abnormal finding of femoral bone density image due to treatment of postoperative lymphatic leakage

  • Han-Kyung Seo;Do-Cheol Choi;Jae-Yung Jeong;Cheol-Min Shim;Yung-Hwan Jeong
    • The Korean Journal of Nuclear Medicine Technology
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    • v.28 no.1
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    • pp.13-17
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    • 2024
  • Bone Mineral Densitometry (BMD) values is determined numerically with T or Z-score while the image is not considered in the interpretation. Abnormal finding was observed in the left femoral bone density image of a 64-year-old female patient who underwent a left kidney transplantation. This was due to the ethiodized oil used for embolization in the treatment of lymphatic leakage. Radiologic technologists should not only monitor changes of BMD values, but keep in mind to assess the changes in the image to provide accurate information to the patient.

Pulmonary Lymphangiomyomatosis - A Case Report - (폐림프관근종증 치험 1례)

  • 정수상;박병률;이종수;양석숭
    • Journal of Chest Surgery
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    • v.26 no.2
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    • pp.160-162
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    • 1993
  • Pulmonary lymphangiomyomatosis is rare but extremely interesting condition caused by progressive widespread smooth muscle proliferation in the perilymphatic regions throughout the lungs. The patient was a 25-year-old female. She had angiofibromas in the face, and angiomyolipoma in the left kidney which was removed 5 years earlier. Three years ago she started having severe dyspnea with bilateral pneumothoraces. Treatment was initiated with bilateral closed thoracotomies followed by open thoracotomy through median sternotomy and lung biopsy, which revealed the diagnosis of pulmonary lymphangiomyomatosis. Recurrence of pneumothorax was treated by repeated chemical pleurodesis with tetracycline. She has been in good condition during medroxyprogesterone administration for 3 years.

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Nephroblastoma of the Avian Leukosis/Sarcoma Group (닭 백혈병(白血病)-육종군(肉腫群)의 신배아종(腎胚芽腫))

  • Lim, Chang Hyeong;Mun, Hi Cheol
    • Korean Journal of Veterinary Research
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    • v.14 no.1
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    • pp.49-51
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    • 1974
  • Nephroblastoma of avian leukosis/sarcoma group was encountered in a Shaver pullet. The tumor, measuring $10{\times}5mm$ in base and 5 mm in height, was located on the surface of anterior lobe of the left kidney. The tumor mass was irregular in shape, firm in consistency and greyish white in color. Histologically, the neoplastic tissues consisted of embryonal uriniferous tubules and fibrosarcomatous stroma.

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Antioxidant Effects of Ascorbic Acid on Renal-Ischemia Reperfusion Injury in Rabbit Model

  • Kim, Jong-Man;Lee, Jae-Yeon;Kim, Duck-Hwan;Jeong, Seong-Mok;Park, Chang-Sik;Kim, Myung-Cheol
    • Journal of Veterinary Clinics
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    • v.25 no.3
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    • pp.165-169
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    • 2008
  • Renal ischemia-reperfusion (I/R) injury is great clinical important because viability of the organ depends on the tolerance to ischemia-reperfusion injury, an inevitable processing during surgery. The purpose of this study was to investigate the effects of premedicated ascorbic acid alone in I/R injury model induced by cross-clamping of renal vessels. In the rabbit models, 2-4 kg New Zealand white rabbits were subjected to 30 minutes of warm unilateral renal ischemia followed by removal of contralateral kidney and then divided into five groups, control (2) arid treatment groups (3). In control group 1, the rabbits only received right nephrectomy. In control group 2, the rabbits received I/R on left kidney after the right nephrectomy. In treatment group 1, the rabbits received ascorbic acid 50 mg/kg IV before the operation. In treatment group 2, the rabbits received ascorbic acid 100 mg/kg IV before the operation. In treatment group 3, the rabbits received ascorbic acid 200 mg/kg IV before the operation. Blood samples were collected from these rabbits for measurement of kidney function tests at the 0, 1 st, 3rd and 7th day and antioxidant enzyme( SOD, GSHPx, CAT) at 24 hours. Kidney function tests (serum creatinine and BUN) showed a significant difference between group 2 and group 4, 5. Activity of antioxidant enzymes in plasma were significant decrease in group 4, 5 compare to group 2. The result of this study suggested that the exogenous ascorbic acid had a role of attenuation of renal I/R injury in rabbit model.