• 한국포장학회지
• /
• 제28권1호
• /
• pp.15-21
• /
• 2022

본 연구는 국내 유통 되는 식품용 유리제 총 110개 제품을 대상으로 유리제에서 식품으로 이행될 우려가 있는 납, 카드뮴 및 바륨에 대하여 이행량을 조사하고 안전성 평가를 실시하였다. 납, 카드뮴 및 바륨은 ICP-OES로 측정되었고, 시험법은 직선성, 검출한계, 정량한계, 회수율, 정밀도 및 측정불확도 추정에 의해 검증되었다. 납과 바륨의 이행량은 각각 불검출 ~ 0.7949 mg/L 및 불검출 ~ 0.1823 mg/L 이었으며, 카드뮴은 모든 시료에서 검출되지 않았다. 식이를 통한 이행물질의 일일추정섭취량 및 위해도를 확인한 결과 국내 유통되는 식품용 유리제는 안전하게 관리되고 있음을 확인하였다.

• 청정기술
• /
• 제17권2호
• /
• pp.124-133
• /
• 2011

2006년 시행되어 온 RoHS 규제에 유해물질을 추가하여 더 강화된 RoHS II의 공표에 대비하여 본 연구에서는 RoHS II의 최우선 규제 물질이면서 2010년 발표된 REACH SVHC 후보목록에도 포함된 물질인 Hexabromocyclododecane (HBCDD) 및 3종 프탈레이트, Dibutyl phthalate (DBP), Butyl benzyl phthalate (BBP), Diethylhexyl phthalate (DEHP)의 국내 전기 전자제품내의 함유 여부를 사전 검토해보려는 목적으로 사례 연구를 진행하였다. 이에 고분자 소재로 구성된 세탁기, 냉장고, 혹은 전자렌지의 부품 20개를 12개 전기전자 부품 생산회사로부터 수거하여 4종 규제 물질을 기체크로마토그래피 질량분석법으로 분석하여 그 함유량을 측정한 결과 Nitrile Butadine Rubber (NBR), Polypropylene (PP), Polybutylene Terephthalate (PBT), Ethylene Propylene Rubber (EPDM), Polyvinyl Chloride (PVC) 등의 소재로 된 부품 중 HBCDD는 NBR 소재로 된 3종 부품에서 42~381 mg/kg 범위로 검출되어 규제값 0.1 wt% (1,000 mg/kg)보다는 적지만 주의를 요한다. DBP 및 BBP는 20개 부품모두에서 검출되지 않고 있어 이 두 물질은 전지전자 제품용 플라스틱 소재에서 넓게 사용되지 않고 있을 가능성을 시사하고 있다. 그러나 DEHP는 40~59,400 mg/kg 범위로 NBR, PP, PBT, EPDM 및 PVC로 이루어진 부품에서 모두 검출되어 광범위하게 사용되고 있음을 알 수 있었고 특히 NBR 및 PVC로 이루어진 8개 부품에서 예상 규제치인 0.1 wt% (1,000 mg/kg)을 훨씬 능가한 0.45~5.94 w%로 검출되고 있어 이에 대한 대비가 필요함을 알 수 있었다. 추가로 REACH SVHC (고위험성 물질)에 속하는 Diarsenic pentaoxide, Diarsenic trioxide, Lead hydrogen arsenate, Triethyl arsenate의 4종 물질의 함유 여부를 ICP에 의한 비소(Arsenic) 분석으로 스크리닝해 본 결과 NBR, PBT 소재의 4개 부품에서 15~700 mg/kg으로 검출되었고 이 중 PBT소재의 부품인 Thermistor에서는 규제되는 비소화합물이 규제값(0.1 wt%, 1,000 mg/kg)을 초과할 가능성이 매우 높다.

• 한국의학물리학회지:의학물리
• /
• 제19권1호
• /
• pp.1-8
• /
• 2008

테크니슘$(^{99m}Tc)$은 현재 핵의학 분야에서 진단용 방사선원으로 가장 널리 쓰이고 있는 방사성 동위원소 중 하나이다. 일반적으로 테크니슘은 $^{99m}Tc$ Generator라 불리는 장치 안에서 모핵종인 $^{99}Mo$의 붕괴를 통해 생산되는데, $^{99}Mo$과 $^{99m}Tc$에서 비교적 높은 방사선을 방출하기 때문에 이를 차폐하기 위하여 주로 납으로 제작되어 있다. 본 논문에서는 국내에서 비교적 사용 빈도가 높고 교정 방사능이 500 mCi인 일본 제품을 대상으로, 최대 방사능량 적제조건에서 차폐용기 표면으로부터 10 cm, 100 cm에서 각각 2.0 mSv/h, 0.02 mSv/h를 초과하지 않아야 한다는 국내 법적 제한치를 만족시키는지 여부를 GEANT4를 이용하여 시뮬레이션하였다. 계산 결과 용기 밖으로 방출되는 방사선량이 법적 기준치를 초과하지 않는 것으로 나타났다.

• 한국환경보건학회:학술대회논문집
• /
• 한국환경보건학회 2003년도 Challenges and Achievements in Environmental Health
• /
• pp.177-180
• /
• 2003

A glassy carbon electrode(GCE) modified with nafion-DTPA-glycerol was used for the highly selective and sensitive determination of a trace amount of Cu$\^$2+/. Various experimental parameters, which influenced the response of nafion-DTPA-glycerol modified electrode to Cu$\^$2+/, were optimized. The copper(II) was accumulated on the electrode surface by the formation of the complex in an open circuit, and the resulting surface was characterized by medium exchange, electrochemical reduction, and differential pulse voltammetry, A linear range was obtained in the concentration range 1.0${\times}$10$\^$-8/M∼1.0${\times}$10$\^$-6/M Cu(II) with 7 min preconcentration. Further, when an approximate amount of lead(II) is added to the test solution, nafion-DTPA-glycerol modified glassy carbon electrode has a dynamic range of 2 orders magnitude(1.0${\times}$10$\^$-9/M∼1.0${\times}$10$\^$-7/M). The detection limit(3 $\sigma$) was as low as 5.0${\times}$10$\^$-6/M(0.032ppb). The interferences from other metal ions could be reduced by adding KCN into the sample solutions. This method was applied to the determination of coppe,(II) in certified reference material(3.23${\times}$10$\^$-7/M, 21ppb), sea water(9.50${\times}$10/sup-7/M, 60ppb). The result agrees satisfactorily with the value measured by Korea Research Institute of Standard and Science.

• 대한치과보철학회지
• /
• 제36권5호
• /
• pp.701-720
• /
• 1998

Research advances in dental implantology have led to the development of several different types of materials and it is anticipated that continued research will lead to advanced dental implant materials. Currently used pure titanium has relatively low hardness and strength which may limit its ability to resist functional loads as a dental implant. Ti-6Al-4V also has potential problems such as corrosion resistance. osseointegration properties and neurologic disorder due to aluminium and vanadium, known as highly toxic elements, contained in Ti-6Al-4V. Newly developed titanium based alloys(Ti-20Zr-3Nb-3Ta-0.2Pd-1In, Ti-20Zr-3Nb-3Ta-0.2Pd) which do not contain toxic metallic components were designed by the Korea Institute of Science and Technology (KIST) with alloy design techniques using Zr, Nb, Ta, Pd, and In which are known as non-toxic elements. Biocompatibility and osseointegration properties of these newly designed alloys were evaluated after implantation in rabbit femur for 3 months. The conclusions were as follows : 1. Mechanical properties of the new designed Ti based alloys(Ti-20Zr-3Nb-3Ta-0.2Pd-1In, Ti-20Zr-3Nb-3Ta-0.2Pd) demonstrated close hardness and tensile strength values to Ti-6Al-4V. 2. New desinged experimental alloys showed stable corrosion resistance similar to the pure Ti but better than Ti-6Al-4V. However, the corrosion rate was higher for the new alloys. 3. Cell culture test showed that the new alloys have similar cell response compared with pure Ti and Ti-6Al-4V with no cell adverse reaction. 4. New designed alloys showed similar bone-metal contact ratio and osseointegration properties compared to pure Ti and Ti-6Al-4V after 3 months implantation in rabbit femur. 5. Four different surface treatments of the metals did not show any statistical difference of the cell growth and bone-metal contact ratio.

• 지구물리와물리탐사
• /
• 제7권1호
• /
• pp.14-18
• /
• 2004

High levels of ambient noise and safety factors often limit the use of 'active-source' seismic methods for geotechnical investigations in urban environments. As an alternative, shear-wave velocity-depth profiles can be obtained by treating the background microtremor wave field as a stochastic process, rather than adopting the traditional approach of calculating velocity based on ray path geometry from a known source. A recent field test in Melbourne demonstrates the ability of the microtremor method, using only Rayleigh waves, to resolve a velocity inversion resulting from the presence of a hard, 12 m thick basalt flow overlying 25 m of softer alluvial sediments and weathered mudstone. Normally the presence of the weaker underlying sediments would lead to an ambiguous or incorrect interpretation with conventional seismic refraction methods. However, this layer of sediments is resolved by the microtremor method, and its inclusion is required in one-dimensional layered-earth modelling in order to reproduce the Rayleigh-wave coherency spectra computed from observed seismic noise records. Nearby borehole data provided both a guide for interpretation and a confirmation of the usefulness of the passive Rayleigh-wave microtremor method. Sensitivity analyses of resolvable modelling parameters demonstrate that estimates of shear velocities and layer thicknesses are accurate to within approximately $10\%\;to\;20\%$ using the spatial autocorrelation (SPAC) technique. Improved accuracy can be obtained by constraining shear velocities and/or layer thicknesses using independent site knowledge. Although there exists potential for ambiguity due to velocity-thickness equivalence, the microtremor method has significant potential as a site investigation tool in situations where the use of traditional seismic methods is limited.

• 한국지진공학회논문집
• /
• 제18권4호
• /
• pp.201-212
• /
• 2014

The plastic hinge region of RC pier ensures its nonlinear behavior during strong earthquake events. It is assumed that the piers secure sufficient strength and ductility in order to prevent the collapse of the bridge during strong earthquake. However, the presence of a lap-splice of longitudinal bars in the plastic hinge region may lead to the occurrence of early bond failure in the lap-splice zone and result in significant loss of the seismic performance. The current regulations for seismic performance evaluation limit the ultimate strain and displacement ductility considering the eventual presence of lap-splice, but do not consider the lap-splice length. In this study, seismic performance test and analysis are performed according to the cross-sectional size and the lap-splice length in the case of longitudinal bars with lap-splice located in the plastic hinge region of existing RC bridge columns with circular cross-section. The seismic behavioral characteristics of the piers are also analyzed. Based upon the results, this paper presents a more reasonable seismic performance evaluation method considering the lap-splice length and the cross-sectional size of the column.

• Mass Spectrometry Letters
• /
• 제13권4호
• /
• pp.146-151
• /
• 2022

Rotigotine (RTG) is a non-ergot dopamine agonist used to manage the early stage of Parkinson's disease (PD) as transdermal patch. However, the poor medication compliance of PD patients and skin issues related with repeated applications of RTG patches lead to the search for alternative formulations and it also requires appropriate analytical methods for their in vivo evaluation. Thus, here, a sensitive, efficient, and cost-effective method to determine RTG in rat plasma using liquid-liquid extraction (LLE) and multiple reaction monitoring was developed. The use of 20 µL of rat plasma for sample treatment, 8-OH-DPAT as the internal standard, and methyl tert-butyl ether as the LLE solvent in the present method gives it advantages over previous methods for the analysis of RTG in biological samples. The good analytical performance of the developed method was confirmed in specificity, linearity (the coefficient of determination ≥0.999 within 0.1-100 ng/mL), sensitivity (the lower limit of quantitation at 0.1 ng/mL), accuracy (81.00-115.05%), precision (≤10.75%), and recovery (81.00-104.48%) by following the FDA guidelines. Finally, the applicability test of the validated method to the in vivo evaluation of a RTG formulation showed that the present method is the only method which can be accurately applied to that longer than 24 hours, critical for the development of formulations with reduced dosing frequencies. Therefore, the present method could contribute to the development of new RTG formulations helpful to people suffering from PD.

• 한국터널지하공간학회 논문집
• /
• 제17권2호
• /
• pp.127-140
• /
• 2015

단층은 굴착공사 중 발생하는 붕괴의 주요원인 중 하나이다. 하지만 단층대 내에서 주요 파괴면으로 작용하는 단층 핵은 파쇄암과 가우지가 불균질하게 분포하는 부분으로서 전단강도의 분포범위가 넓기 때문에 안정성 해석 시 경험적으로 결정되는 경우가 많다. 본 연구에서는 경주와 울산의 12개 지점에서 채취한 62개의 단층 핵 시료를 대상으로 직접전단시험과 입도 분석을 수행하였다. 실내시험으로 얻어진 결과를 이용하여 회귀 분석을 수행하여 수직응력별 입도에 따른 전단강도의 범위를 결정하였다. 자갈의 무게비는 전단강도와 비례하며, 실트 및 점토의 무게비는 반비례하는 것으로 나타났다. 결정계수는 대부분 약 0.7 이상으로 시료의 불균질성을 고려할 때 비교적 높게 나타났으며, 분석된 회귀모형의 95% 신뢰 구간을 설정하여 무게비에 따른 전단강도의 상한과 하한 범위를 결정하였다.

• 한국환경농학회지
• /
• 제37권3호
• /
• pp.197-206
• /
• 2018

BACKGROUND: The present study aimed to examine the crops capable of growing and adapting to the external environment and various stresses of reclaimed agriculture land for the development of high value-added agricultural utilization technology based on reclaimed land through standardization and empirical study of cultivation environment for cultivating crops. METHODS AND RESULTS: Two crops namely turnips and beets were selected for the salt tolerance test of soil environmental conditions on reclaimed land. Turnip and beet seedlings were planted on the soil collected at the 'Seokmun' reclaimed land. There are five treatments such as non-treatment, 1.0, 2.0 (control), 4.0 and $8.0dS{\cdot}m^{-1}$ of EC. The contents of betacyanin in beet roots was highest in control and decreased with increasing salt concentration. The GSL contents in the turnip roots waswere highest at EC 2.0 and decreased with increasing salt concentration, whereas those in turnip leaves waswere high both in the non-treated control and atthe EC 1.0-treatment. But, tThere was, however, no statistical differences among the treatments. CONCLUSION: The degree of salt tolerance of crops was examined, and the limit EC iswas expected to be $3.0{\sim}4.0dS{\cdot}m^{-1}$ as reported to date. If the soil improvement is performed and irrigation systems are used in the actual reclaimed land, the EC of supplied irrigation will be low, and desalination effecttreatment by the lower EC of the supplied irrigation on the soil will lead to more favorable soil condition of the rhizosphere and cultivation environment offor the crops than those in the port experiment. Therefore, monitoring the salinity, water content and ground water level will enable prediction of the rhizosphere environment, and setting up irrigation management and supplying irrigation will lead to crop cultivation results that are close to normal.