• Journal of Korea Association of Health Promotion
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• v.3 no.1
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• pp.55-61
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• 2005

Functional constipation is regarded as a long-standing symptomatic manifestation of abnormal defecation expressed by either a reduced frequency of bowel movements and /or an altered act of evacuation. Patients with constipation can be treated with laxatives, diets and regular habits. Thorough evaluation of functional constipation is considered in those in whom conservative treatment with dietary advice and use of laxatives fails. Patients with normal colonic transit and normal anorectal function may only need reassurance, education and dietary advice with fiber supplementation. For constipated patients in whom such treatment modalities fail, laxatives including bulk-forming and osmotic agents may be used Although most laxatives, if used intermittently, are relatively safe, they must be chosen bearing in mind possible side effects, patient compliance and their action mechanisms. A subgroup of patients with slow transit through the colon ay be unresponsive to conventional laxatives, and, in these subjects, a trial with enteroprokinetics and sometimes stimulant laxatives should be attempted. This article presents our view of the assessment and pharmacologic treatment of functional constipation.

• The Journal of Internal Korean Medicine
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• v.39 no.5
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• pp.1052-1060
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• 2018

Objectives: This study reports the effect of herbal medicine to replace laxatives for patients with chronic constipation. Methods: The patients who took laxatives due to long-term constipation were prescribed herbal medicine instead. We assessed whether they could defecate without laxatives and if their bowel habits improved using only herbal medicine. Results: The use of herbal medicine instead of laxatives improved patients' defecation and reduced symptoms such as hard stool, difficulty during defecation, and sensation of incomplete evacuation. Conclusions: Through two cases, we found that herbal medicine is effective for patients who are dissatisfied with laxatives.

• The Korean Journal of Nuclear Medicine Technology
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• v.18 no.1
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• pp.3-9
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• 2014

Purpose: Our goals were to evaluate the effect of high dose radioiodine treatment for thyroid cancer by taking in laxatives. Materials and Methods: Twenty patients(M:F=13:7, age $46.3{\pm}8.1\;yrs$) who underwent high dose radioiodine treatment were seperated into Group 1 taking $^{131}I$ 5,500 MBq and Group 2 with the use of laxatives after taking $^{131}I$ 5,500 MBq. The whole body was scanned 16 hours and 40 hours after taking radioactive iodines by using gamma camera, the ROIs were drawn on the gastro-intestinal tract and thigh for calculation of reduction ratio. At particular time during hospitalization, the radioactivity remaining in the body was measured in 1 meter from patient by using survey meter (RadEye-G10, Thermo Fisher Scientific, USA). Schematic presentation of an Origin 8.5.1 software was used for spatial dose rate. Statistical comparison between groups were done using independent samples t-test. P value less than 0.05 was regarded as statistically significant. Results: The reduction ratio in gastro-intestinal 16 hours and 40 hours after taking laxatives is $42.1{\pm}6.3%$ in Group 1 and $72.1{\pm}6.4%$ in Group 2. The spatial dose rate measured when discharging from hospital was $23.8{\pm}6.7{\mu}Sv/h$ in Group 1 and $8.2{\pm}2.4{\mu}Sv/h$ in Group 2. The radioactivity remaining in the body is much decreased at the patient with laxatives(P<0.05). Conclusion: The use in combination with laxatives is helpful for decreasing radioactivity remaining in the body. The radioactive contamination could be decreased at marginal individuals from patients.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.13 no.1
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• pp.60-67
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• 2006

Purpose: To identify the relationship between medication use and falls among hospitalized stroke patients. Method: The medical records of 472 patients with strokes were reviewed using a questionnaire on falling developed by the authors. Frequencies, percentages, means, standard deviations, and t-test and ${\chi}^2$-test, multiple logistic regression analysis were done using the SAS program. Results: The rate for falls by the patients during their stay in the hospital was 14.0%. The length of stay was longer and the morbidity duration of stroke shorter in the fall group than in the non-fall group. The use of sedatives, laxatives, and antidepressants was a significant predictor of falls and was associated with increase likelihood of falling(1.82, 1.81, 1.75 times respectively). Conclusion: In hospitalized stroke patients, there was a significant association between the use of sedatives, laxatives, antidepressants and falls. The number and kinds of ingested drugs was also associated with falls. It is necessary to further analyze the causes of falls based on results of the present study.

• Child Health Nursing Research
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• v.13 no.1
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• pp.90-101
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• 2007

Purpose: To evaluate the effects of abdominal meridian massage either with the use of aroma oils or without using the oils for the relief of constipation in institutionalized children with cerebral palsy. Method: Using a nonequivalent control group pretest-posttest design, 40 children were randomly assigned to experimental (n=21) and control (n=19) groups. The experimental group received abdominal meridian massage with mixture of aroma oils, and the control group received abdominal meridian massage only. Prior to the intervention, baseline data were collected, and then abdominal meridian massage with or without aroma oils were given to both groups every morning for 15 minutes a day, six days a week, for 2 weeks. Outcome measures were number of bowel movements, amount of stool (gm), and frequency of laxatives, suppositories or enema. Using SPSS/Win 12.0 program, data were analyzed by $X^2$ test, t-test, and repeated measures ANOVA. Results: Children in the experimental group defecated a larger volume of stool, and used fewer laxatives than those in the control group. The treatment effects lasted for 1 week after treatment. Conclusion: Abdominal meridian massage with aroma oils appears to be an effective adjunct maneuver in relieving constipation among institutionalized children with cerebral palsy.

• Advances in pediatric surgery
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• v.19 no.2
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• pp.130-139
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• 2013

The application of laparoscopic techniques for the surgical management of Hirschsprung's disease is the recent trend. We described the surgical technique and postoperative long-term outcomes of the one-stage, laparoscopic-assiseted endorectal pull-through operation for Hirschsprung's disease. The technique uses three to four small abdominal ports. Laparoscopic mobilization of the sigmoid colon and rectum is performed and marginal artery-preserving colon pedicle is prepared. The rectal mobilization is performed using a transanal endorectal sleeve technique. The anastomosis is performed 0.5~1 cm above the dentate line. The age at surgery ranged from 6 days to 4 years. The average operative time was 144 minutes. Almost all of the patients passed stool and flatus within 36 hours of surgery. The average hospital stay after surgery was 6.5 days. Among 42 patients, 32 patients older than 3 years old were evaluated for function on defecation. All 32 patients have been continent, of those who needed laxatives were 11 (34.3%) due to constipation and overflow incontinence. Four children (12.5%) have remained dependent on laxatives. Laparoscopic-assisted endorectal pull-through operation for Hirschsprung's disease appears to be safe, provides the less pain, shorter time to full feeding, shorter hospital stay, and excellent cosmetic outcomes. Helping patients and parents ensure the quality of life, they should be provided with counseling, education, and longer-term follow-up care.

• The Journal of Korean Academic Society of Nursing Education
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• v.10 no.2
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• pp.252-261
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• 2004

Purpose: This study attempts to develop the basic data of Constipation reduction program for institutionalized elderly by surveying the constipation and the ADL (Activities of Daily Living) of them. Method: Data are collected by nurses caring for four hundreds five institutionalized elderly during May through July in 2004. Questionnaire contains a bowel assessment, constipation control intervention, and ADL. Result: The constipation rate was found to be 43%. The 82.5% of the study sample was treated with laxatives, and a 59.9% of the sample was practicing enema. The average score of the ADL was 38.32(range: 0 - 100). According to surveying on the ADL in relation to the function of the constipation, ADL is found to be higher in the non-constipation group than the constipation group (t=-2.786, p=.006). Conclusions: The institutionalized elderly tended to have a high rate of constipation. The elderly having constipation was almost dependent on laxatives and enema for relaxing constipation. The high rate of constipation was related to the low performance of the ADL.

• The Korean Journal of Pain
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• v.32 no.2
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• pp.69-78
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• 2019

Pain therapy often entails gastrointestinal adverse events. While opioids are effective drugs for pain relief, the incidence of opioid-induced constipation (OIC) varies greatly from 15% to as high as 81%. This can lead to a significant impairment in quality of life, often resulting in discontinuation of opioid therapy. In this regard, a good doctor-patient relationship is especially pivotal when initiating opioid therapy. In addition to a detailed history of bowel habits, patient education regarding the possible gastrointestinal side effects of the drugs is crucial. In addition, the bowel function must be regularly evaluated for the entire duration of treatment with opioids. Furthermore, if the patient has preexisting constipation that is well under control, continuation of that treatment is important. In the absence of such history, general recommendations should include sufficient fluid intake, physical activity, and regular intake of dietary fiber. In patients of OIC with ongoing opioid therapy, the necessity of opioid use should be critically reevaluated in terms of an with acceptable quality of life, particularly in cases of non-cancer pain. If opioids must be continued, lowering the dose may help, as well as changing the type of opioid. If these measures do not suffice, the next step for persistent OIC is the administration of laxatives. If these are ineffective as well, treatment with peripherally active ${\mu}$-opioid receptor antagonists should be considered. Enemas and irrigation are emergency measures, often used as a last resort.

• YAKHAK HOEJI
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• v.27 no.1
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• pp.37-43
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• 1983

The rhizome of Polygonum sachalinense Fr. Schm. (=Reynoutria sachalinensis Nakai, Polygonaceae) has been used as "Polygoni Rhizoma" (Hu Zhang) in the Orient as laxatives, diuretics and for treatment of suppurative dermatitis, gonorrhoea, favus and athlete's foot. From the methanolic extract of the dried rhizome physcion, emodin, emodin-8-O-$\beta$-D-glucoside as anthraquinone derivatives and .betha.-sitosterol glucoside were isolated and identified. Stilbene derivatives which have antibacterial and antifungal activities were also isolated.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.6
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• pp.1331-1346
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• 2008

The aim of this study was to establish opinions of Kum Won Sa dea ga on jaundice and find out clinical significance. Contents dealing with jaundice were searched manually in works of Kum Won Sa dea ga. Those were translated into Korean and studied. Yoo wan so(劉完素) had opinion that jaundice is induced by dampness with heatness(濕熱) or dryness with heatness(濕熱) and should be treated with diuretics and laxatives. Jang jong jung(張從政) had opinion that jaundice is induced by spleen(脾) mainly and should be treated with diaphoretics, emetics, laxatives. Lee dong won(李東垣) had opinion that jaundice is induced by mistaken diaphoretics, dysfunction of spleen(脾), heatness(熱) and treatments should depend on six meridian pathways(六經). Ju jin hyeong(朱震亨) had opinion that jaundice is induced by dampness with heatness(濕熱) and coldness with dampness(濕熱) and should be treated with diuretics and detoxicant. Kum Won Sa dae ga thought jaundice in induced by dampness with heatness(濕熱) and explained pathology by the five viscera and the six entrails(五臟六腑). And they treated patients with jaundice according to etiologic source.