• 대한족부족관절학회지
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• 제27권4호
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• pp.123-130
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• 2023

Purpose: "Hallux valgus" is a common disease encountered in clinical practice and is accompanied by foot deformities. Conservative treatment is commonly used in the early stages of hallux valgus. On the other hand, surgical treatment often becomes necessary as the deformity progresses. Surgical treatments involve various osteotomy methods or joint fusion procedures combined with soft tissue release, and outcomes from these surgical treatments are generally favorable. This study compared two soft tissue release techniques in the hallux region. Materials and Methods: This study conducted a retrospective cohort study on 48 participants who underwent surgical treatment for hallux valgus at a single institution from March 1, 2018, to March 31, 2023. A scarf osteotomy was performed in all cases, and the "Modified Mcbride procedure" or "Trans-articular approach" was done for soft tissue release. Hallux valgus angle (HVA), intermetatarsal angle (IMA), and the degree of subluxation of the lateral sesamoid were measured through simple foot radiographs taken before surgery and one year after surgery. Results: In the Modified Mcbride procedure group, HVA, IMA, and the sesamoid position grade decreased from 34.94° to 9.98°, 15.64° to 5.44°, and 2.47 to 0.44, respectively. In the trans-articular approach group, HVA, IMA, and the sesamoid position grade decreased from 33.42° to 7.34°, 15.06° to 6.03°, and 2.17 to 0.58, respectively. There was no significant difference in these changes between the preoperative and one-year postoperative measurements for both techniques (p-value>0.05). Conclusion: A radiological assessment of soft tissue release through the Modified Mcbride procedure and trans-articular approach in hallux valgus did not show significant differences. Therefore, both surgical techniques can be considered in the distal soft tissue release for a hallux valgus correction.

• Archives of Plastic Surgery
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• 제47권6호
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• pp.622-625
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• 2020

Corner mouth lift is in increasing demand among young patients in East Asia. Although various surgical methods exist for corner mouth lift, many patients are reluctant to undergo surgery due to fears of postsurgical scarring. We present a new technique aimed at reducing postoperative scarring. The technique involves triangular excision of the corner of the mouth and incision of the commissure with transposition of a lateral vermilion flap to lift the corner of the mouth. The muscle around the corner of the mouth is dissected to release tension. The corner mouth lift was successfully performed in all patients. It can be effectively used even in patients, such as young Asian women, who are susceptible to hypertrophic scars.

• BMB Reports
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• 제50권5호
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• pp.237-246
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• 2017

Synapse is the basic structural and functional component for neural communication in the brain. The presynaptic terminal is the structural and functionally essential area that initiates communication and maintains the continuous functional neural information flow. It contains synaptic vesicles (SV) filled with neurotransmitters, an active zone for release, and numerous proteins for SV fusion and retrieval. The structural and functional synaptic plasticity is a representative characteristic; however, it is highly vulnerable to various pathological conditions. In fact, synaptic alteration is thought to be central to neural disease processes. In particular, the alteration of the structural and functional phenotype of the presynaptic terminal is a highly significant evidence for neural diseases. In this review, we specifically describe structural and functional alteration of nerve terminals in several neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Amyotrophic lateral sclerosis (ALS), and Huntington's disease (HD).

• International Journal of Industrial Entomology and Biomaterials
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• 제29권1호
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• pp.120-127
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• 2014

The cerebral neurosecretory cells (NSC) constitute four paired groups, medial (MNC), lateral (LNC-I, LNC-II) and posterior (PNC) in the brain of larvae of tasar silkworm Antheraea mylitta (D) Eco-race Bhandara. The MNC is the largest groups of peptidergic neurosecretory cells and are located in the pars intercerebralis region. The transmission electron microscopic (TEM), ultrastructure of the NSC confirmed the presence of mitochondria, endoplasmic reticulum, Golgi bodies, lysosomes and neurosecretory granules. The median neurosecretory cells shows secretory activity and release of secretory products, the neurosecretory granules (NSG) in the axons of NSC as well as the blood sinus.

• 대한관절경학회지
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• 제5권2호
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• pp.104-110
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• 2001

목적 : 슬개골 탈구에 동반된 골연골 골절의 양상을 분석하고 관절경적 치료에 따른 임상결과를 평가하고자 한다. 대상 및 방법 : 1989년 3월부터 1998년 4월까지 경험한 슬개골 탈구 환자 중 골연골 골절을 동반하여 관절경적으로 치료한 14례를 대상으로 평균 32개월 추시하였다. 전례에서 관절경적 시술을 하였으며 수술시 골절편의 위치와 크기를 기록하였다. 결과는 Larsen과 Lauridson의 방법으로 평가하였다. 결과 : 골연골 골절의 위치는 슬개골의 내측면이 8례, 외측면이 1례, 대퇴외과의 외측면이 5례였다. 각 골연골 골편의 최대 직경의 범위는 1cm에서 4.2cm이었고 치료는 절제술만 시행한 경우가 6례, 절제술과 내측지대 봉합술을 병행한 경우가 2례, 절제술과 내측지대 봉합술, 외측지대 이완술을 같이 한 경우가 3례, 고정술만 시행한 경우가 3례 있었다. 기능적 결과는 우수 5례, 양호 6례 보통 1례, 그리고 불량이 2례였다. 결론 : 슬개골 탈구에 동반된 골연골 골절에 대한 관절경적 치료는 최소한의 절개와 철저한 관절내 병변의 파악을 통한 적절한 치료 방법의 선택으로 합병증을 최소화할 수 있는 좋은 방법이 라 사료된다.

• 한국화재소방학회논문지
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• 제29권4호
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• pp.67-72
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• 2015

본 연구는 콘칼로리미터 실험을 통해 건축물 마감재와 가구소재로 널리 적용되는 목재 가공품의 화염연소와 훈소시 화재특성을 파악하고자 한다. 시험대상 목재 가연물은 MDF, 합판, 칩보드이며 $50kW/m^2$의 복사열유속을 시편에 가하여 점화를 유도하였다. 실험과정에서 화재특성을 나타내는 발열량, 연소가스 생성율, 유효연소율 등의 주요 인자를 가연물의 두께에 따라 정량화하였다. 실험결과 초기 평면방향의 화염전파와 후기 시편의 관통에 의한 화재확대로 인해 단위면적당 발열량에 대한 두 개의 피크점이 관측되었다. 화염연소시의 질량감소율이 훈소시에 비해 5배 이상 높게 나타난 반면에 훈소과정에서 CO 생성율은 화염연소에 비해 10배 이상 높게 측정되어 훈소시 높은 독성가스 생성율을 보였다. 본 연구는 목재 가연물의 화재성상을 이해하고 화재해석을 위한 물성자료로 활용될 수 있다.

• Archives of Plastic Surgery
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• 제35권6호
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• pp.716-722
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• 2008

Purpose: Split or full thickness skin graft is generally used to reconstruct the palmar skin and soft tissue defect after release of burn scar flexion contracture of hand. As a way to overcome and improve aesthetic and functional problems, the authors used the preserved superficial fat skin(PSFS) composite graft for correction of burn scar contracture of hand. Methods: From December of 2001 to July of 2007, thirty patients with burn scar contracture of hand were corrected. The palmar skin and soft tissue defect after release of burn scar contracture was reconstructed with the PSFS composite graft harvested from medial foot or below lateral and medial malleolus, with a preserved superficial fat layer. To promote take of the PSFS composite graft, a foam and polyurethane film dressing was used to maintain the moisture environment and Kirschner wire was inserted for immobilization. Before and after the surgery, a range of motion was measured by graduator. Using a chromameter, skin color difference between the PSFS composite graft and surrounding normal skin was measured and compared with full thickness skin graft from groin. Results: In all cases, the PSFS composite graft was well taken without necrosis, although the graft was as big as $330mm^2$(mean $150mm^2$). Contracture of hand was completely corrected without recurrence. The PSFS composite graft showed more correlations and harmonies with surrounding normal skin and less pigmentation than full thickness skin graft. Donor site scar was also obscure. Conclusion: The PSFS composite graft should be considered as a useful option for correction of burn scar flexion contracture of hand.

• Archives of Plastic Surgery
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• 제34권5호
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• pp.587-592
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• 2007

Purpose: In case of postburn flexion contracture of the fingers, skin graft, geometrical relaxation techniques, local flap, and free flap have been used. Among these procedures, full-thickness skin grafts from the inguinal area are widely used to reconstruct a postburn flexion contracture in the fingers. But there are many esthetic and functional problems in this procedure. Especially, hyperpigmentation of the skin-grafted fingers poses a troublesome problem, particularly in the patients who have dark colored skin. To solve the problem, we have used pulp graft which was harvested from the lateral aspect of great toe. In the present study, we report pulp graft, with which we have obtained a good result in the treatment of postburn flexion contracture of the fingers. Methods: Between September of 2004 and August of 2006, great toe pulp graft was performed to 20 sites of 15 patients. After release of the postburn flexion contracture using Z-plasty, the composite tissue (pulp) harvested from the lateral aspect of great toe was grafted on the raw surface. Moisture dressing with ointment and foam dressing material was performed. Stratum corneum of the graft got stripped off in two to four weeks after pulp graft. The color of the pulp graft was slightly reddish, then it became similar to the adjacent tissue. Results: There was complete take in all the patients who were treated with pulp graft. Great toe pulp graft provided similar color and texture to the adjacent skin, high rate of graft take, and left only a minimal scar at donor site. Conclusion: Thick keratin layer and inelastic nature of the pulp make this type of the graft much easier and simpler, and ensure a better take. Pulp graft is useful method for the reconstruction of the postburn flexion contracture in fingers.

• 대한수의학회지
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• 제48권3호
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• pp.251-258
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• 2008

The neurotoxicity of C-terminal fragments of amyloid precusor protein (CT) is known to play some roles in Alzheimer's disease progression. In this study, we investigated the effects of the recombinant C-terminal 105 amino acid fragment of amyloid precusor protein (CT105) on cholinergic function using CT105-injected rat. To study the effects of CT105 on septohippocampal pathway, choline acetyltransferase (ChAT) positive neurons were examined in the medial septum and in the diagonal band after an injection of CT105 peptide into the lateral ventricle. Immunohistological analysis revealed that the number of ChAT-immunopositive cells decreased significantly in both medial septum and diagonal band. In addition, CT105 decreased ChAT-immunopositive cells in the hippocampal area, particulary in the dentate gyros. To study the effect of amyloid beta peptide ($A{\beta}$) and CT105 on the cholinergic system, each peptide was injected into the left lateral ventricle, and acetylcholine (ACh) levels were monitored in hippocampus. ACh level in the hippocampal area was reduced to 60% of control level in $A{\beta}$-treated group, and the level was reduced to 15% of control level in CT105-treated group, at one week after the injection. ACh level was further reduced to 35% of control in $A{\beta}$-treated group, whereas the level was slightly increased to 30% of control in CT105-treated group at 4 weeks after the injection. Taken together, the results in the present study suggest that CT105 impairs the septohippocampal pathway by reducing acetylcholine synthesis and release, which results in damage of learning and memory.

• 한국운동역학회지
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• 제24권3호
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• pp.217-227
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• 2014

The purpose of this study was to investigate the relationship between distance and factors of javelin in korean male's javelin throwing. To accomplish this purpose, the analyzed trail selected total 29 trails (subjects 9) recorded more than 65 m in the 93rd National Sports Festival. The Kwon3D 3.1 version was used to obtain the three dimensional coordinates about the top, grip, end of javelin. And the kinematic data such as projection factors and direction angle of javelin calculated using Matlab2009a program. The statical analysis on the records (n=29) were used to Pearson's product moment correlation coefficient. There was a statistically positive relationship between the records and horizontal velocity (r=.866, ${\rho}$<.01), height (r=.541, ${\rho}$ <.001), height rate (r=.373, ${\rho}$ <.05) and horizontal displacement of javelin (r=.749, ${\rho}$ <.01), but the medial/lateral velocity showed a negative relationship to r=-.663 (${\rho}$ <.01). The attack and yaw angle showed not a significant relationship between the records, but the medial-lateral tilt (E1:r =-.557 [p<.01)] E2:r=-.629 [${\rho}$<.01], E3:r=-.528 [${\rho}$ <.01]) and attitude angle (E2:r=-.629 [[${\rho}$<.01], E3:r=-.619 [${\rho}$ <.01]) of javelin showed a negative relationship between the records, as well as the projection angle of javelin (r=-.419, ${\rho}$ <.05) showed a negative relationship between the records.