• 제목/요약/키워드: lateral flow test

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편재하중을 받는 연약지반의 측방유동에 관한 연구 (A Study on the Lateral Flow in Soft Soils subjected to Unsymmetrical Surcharges)

  • 안종필
    • 지질공학
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    • 제3권2호
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    • pp.177-190
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    • 1993
  • 연약지반에서 성토나 교대등에 의한 편재하중이 작용하게 되면 지반중에는 침하, 측방변위, 융기 및 전단파괴 등의 큰 소성적인 전단변형이 발생하여 지반 및 구조물에 큰 피해를 주는 것을 많이 볼 수 있다. 본 연구는 이러한 연약지반에서 편재하중에 의한 지반의 제반변형에 대한 거동을 연구하기 위하여 기존의 이론적인 배경을 조사하고 모형실험을 통한 실측치를 이용하여 서로 비교분석하여 보았다. 모형실험은 먼저 모형재하장치를 제작하고 토조안에 연약한 흙시료를 채워 비배수상태에서 일정한 시간간격으로 하중단계를 증가시켜 가면서 변형의 상태를 관측하였다. 실험결과를 토대로 지반특성과 변위량의 관계, 한계하중 및 극한지지력, 지반의 소성유동의 상태 및 측방 유동압의 검토 등을 상세하게 분석하여 기존의 이론과 비교해 봄으로써 실제 연약지반상에서의 측방변형에 대한 원인을 규명함으로써 그로 인한 피해를 사전에 방지하고자 한다.

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The motion rule of sand particles under control of the sand transportation engineering

  • Xin, Lin-gui;Cheng, Jian-jun;Chen, Bo-yu;Wang, Rui
    • Wind and Structures
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    • 제27권4호
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    • pp.213-221
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    • 2018
  • In the desert and Gobi regions with strong wind and large sediment discharge, sand transporting engineering is more effective than sand blocking and sand fixing measures in sand prevention. This study uses the discrete phase model of 3D numerical simulation to study the motion trail, motion state and distribution rule of sand particles with different grain diameters when the included angle between the main shaft of the feather-row lateral transportation sand barrier and the wind direction changes, and conducts a comparison in combination with the wind tunnel test and the flow field rule of common sand barrier. According to the comparison, when wind-sand incoming flow passes through a feather-row sand barrier, sand particles slow down and deposit within the deceleration area under the resistance of the feather-row sand barrier, move along the transportation area formed by the transportation force, and accumulate as a ridge at the tail of the engineering. With increasing wind speed, the eolian erosion of the sand particles to the ground and the feather-row sand barrier is enhanced, and the sand transporting quantity and throw-over quantity of the feather-row sand barrier are both increased. When sand particles with different grain diameters bypass the feather-row sand barrier, the particle size of the infiltrating sands will increase with the included angle between the main shaft of the feather-row sand barrier and the wind direction. The obtained result demonstrates that, at a constant wind speed, the flow field formed is most suitable for the lateral transportation of the wind-drift flow when the included angle between the main shaft of the feather-row sand barrier lateral transportation engineering and the wind speed is less than or equal to $30^{\circ}$.

Effects of excess pore pressure dissipation on liquefaction-induced ground deformation in 1-g shaking table test

  • Wang, B.;Zen, K.;Chen, G.Q.;Kasama, K.
    • Geomechanics and Engineering
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    • 제4권2호
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    • pp.91-103
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    • 2012
  • Focusing on the effect of excess pore pressure dissipation on liquefaction-induced ground deformation, a series of 1-g shaking table tests were conducted in a rigid soil container by use of saturated Toyoura sand, the relative density of which was 20-60%. These tests were subjected to the sinusoidal base shaking with step increased accelerations: 100, 200, 300 and 400 Gals for 2-4 seconds. Shaking table tests were done using either water or polymer fluid with more viscous than water, thus varying the sand permeability of model tests. Excess pore pressures, accelerations, settlements and lateral deformations were measured in each test. Test results are presented in this paper and the effect of sand permeability on liquefaction and liquefaction-induced ground deformation was discussed in detail.

횡방향 새그를 가진 자정식 현수교의 공탄성 거동(I) -주형의 거동을 중심으로- (Aeroelastic Behaviors of Self-anchored Suspension Bridge with Lateral Sag of Main Cable(I) -Focused on the Behavior of Girder-)

  • 권순덕;장승필
    • 한국강구조학회 논문집
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    • 제9권2호통권31호
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    • pp.259-267
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    • 1997
  • 본 연구에서는 주 케이블에 횡방향 새그를 가진 자정식 현수교의 내풍안정성을 검토하기 위하여 풍동실험을 수행하고, 주형의 거동을 중심으로 그 결과를 분석하였다. 등류와 난류하에서 수행한 부분 모형 실험에서 가장 내풍안정성이 뛰어난 단면을 최종단면으로 선정하고, 전교 모형 실험을 통하여 검증하였다. 또한 차후 연구를 위한 플러터 계수를 측정하여 제시하였다. 교량의 사용성과 피로문제를 검토하기 위하여 버페팅 응답을 조사하였지만, 공학적 관점에서 만족할 만한 수준인 것으로 나타났다. 주형의 항력계수가 상당히 큼에도 불구하고 횡방향 변위가 매우 작게 나타났는데, 이는 주 케이블의 횡방향 새그가 주형의 변위를 구속하기 때문인 것으로 판단된다.

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PCR 방법과 면역학적 분석법을 이용한 두부와 비지에서 GM 콩의 검출법 (Detection of Genetically Modified Soybean in Tofu and Biji using PCR and Immunological Methods)

  • 김묘영;김재환;김해영
    • Applied Biological Chemistry
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    • 제48권1호
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    • pp.77-81
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    • 2005
  • GM 콩으로 제조된 두부와 비지 등 콩 가공제품들의 효율적인 모니터링을 위하여 GM 콩이 0%, 1%, 3%, 5%, 100% 함유된 두부와 비지를 제조하여 이들의 삽입유전자인 5-enolpyruvylshikimate-3-phosphate synthase(epsps)를 검출하기 위한 PCR 방법과 EPSPS 발현 단백질 검출을 위한 western blotting과 lateral flow strip을 사용하여 검출 감도를 비교하였다. PCR 결과 산물의 크기가 큰 600 bp의 증폭에서 두부의 경우에는 100% GM으로 제조된 두부에서만 확인이 가능하였고, 비지에서는 5%, 100%에서 확인이 되었다. 크기가 작은 123 bp가 생성되는 실험에서는 0%를 제외한 모든 두부와 비지에서 검출되었다. Western blot 결과는 100% 두부, 비지에서만 검출이 되었고, lateral flow strip test에서는 100% 비지에서만 검출되었다. 이러한 결과로부터 GM 콩 가공식품 검출은 면역학적 방법보다는 PCR이 더 높은 민감도가 나타내는 것을 확인하였고, 또한 가공식품에서 효율적인 GMO 검출을 위해서는 100 bp 정도의 작은 크기의 PCR 산물을 이용해야 민감한 검출 결과를 보여주는 것을 확인하였다.

Centrifuge modelling of pile-soil interaction in liquefiable slopes

  • Haigh, Stuart K.;Gopal Madabhushi, S.P.
    • Geomechanics and Engineering
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    • 제3권1호
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    • pp.1-16
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    • 2011
  • Piles passing through sloping liquefiable deposits are prone to lateral loading if these deposits liquefy and flow during earthquakes. These lateral loads caused by the relative soil-pile movement will induce bending in the piles and may result in failure of the piles or excessive pile-head displacement. Whilst the weak nature of the flowing liquefied soil would suggest that only small loads would be exerted on the piles, it is known from case histories that piles do fail owing to the influence of laterally spreading soils. It will be shown, based on dynamic centrifuge test data, that dilatant behaviour of soil close to the pile is the major cause of these considerable transient lateral loads which are transferred to the pile. This paper reports the results of geotechnical centrifuge tests in which models of gently sloping liquefiable sand with pile foundations passing through them were subjected to earthquake excitation. The soil close to the pile was instrumented with pore-pressure transducers and contact stress cells in order to monitor the interaction between soil and pile and to track the soil stress state both upslope and downslope of the pile. The presence of instrumentation measuring pore-pressure and lateral stress close to the pile in the research described in this paper gives the opportunity to better study the soil stress state close to the pile and to compare the loads measured as being applied to the piles by the laterally spreading soils with those suggested by the JRA design code. This test data shows that lateral stresses much greater than one might expect from calculations based on the residual strength of liquefied soil may be applied to piles in flowing liquefied slopes owing to the dilative behaviour of the liquefied soil. It is shown at least for the particular geometry studied that the current JRA design code can be un-conservative by a factor of three for these dilation-affected transient lateral loads.

복합통수능시험기를 이용한 실린더형 플라스틱 보드 드레인의 성능 평가 (Capacity Evaluation of Cylindrical Plastic Board Drain with The Composite Discharge Capacity Apparatus)

  • 이찬우;정두회;김윤태;진규남
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2008년도 춘계 학술발표회 초청강연 및 논문집
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    • pp.293-299
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    • 2008
  • If a conventional type of Plastic Board Drain (PBD) is installed to the deep clay deposit, it is subjected to a high lateral earth pressure. a flow channel of PBD may be reduced by the collapse of cores and clogged by the intrusion of filter into the space between cores which are made by lateral pressure. It could decrease the ability of initial discharge capacity and the reliability of long term discharge capacity. A cylindrical plastic board drain (C-PBD) considered in this study consists of cylindrical core and several supports so that it can prevent the reduction of area of flow channel from the higher lateral earth pressure effectively. The discharge capacity of C-PBD was compared to that of a conventional PBD through performing experiments using the composite discharge capacity apparatus which can consider in-situ condition such as penetration of drains, ground settlement and discharge capacity. As a result, C-PBD showed much better performance than PBD in the ability of discharge. It was observed that the C-PBD was folded whereas the conventional PBD was folded after the experiment.

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Are Accuracy Studies for Periprosthetic Joint Infection Diagnosis Inherently Flawed? And What to Do with Schrödinger's Hips? A Prospective Analysis of the Alpha Defensin Lateral-Flow Test in Chronic Painful Hip Arthroplasties

  • Jesse W.P. Kuiper;Steven J. Verberne;Pim W. van Egmond;Karin Slot;Olivier P.P. Temmerman;Constantijn J. Vos
    • Hip & pelvis
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    • 제34권4호
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    • pp.236-244
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    • 2022
  • Purpose: The most recent diagnostic criteria for periprosthetic joint infection (PJI) include the use of the alpha-defensin (AD) lateral-flow (LF) test, but hip and knee arthroplasties were usually combined in previous studies. This prospective study was designed to examine the accuracy of the AD-LF test for diagnosis of PJI in chronic painful total hip arthroplasties (THA). Materials and Methods: Patients with chronic painful hip arthroplasties were prospectively enrolled between March 2018 and May 2020. Exclusion criteria included acute PJI or an insufficient amount of synovial fluid. The modified Musculoskeletal Infection Society (MSIS) criteria were primarily used for PJI diagnosis. Fifty-seven patients were included in the analysis group. Revision surgery was not performed in 38 patients, for different reasons (clinical group); these patients remain "Schrödinger's hips": in such cases PJI cannot be excluded nor confirmed until you "open the box". Results: The result of the AD-LF test was positive in nine patients and negative in 48 patients. Six patients were diagnosed with PJI. AD-LF sensitivity (MSIS criteria) was 83% (95% confidence interval [CI] 36-100%) and specificity was 92% (95% CI 81-98%). The positive and negative predictive value were 56% and 98%, respectively. Conclusion: The AD test is useful in addition to the existing arsenal of diagnostic tools, and can be helpful in the decision-making process. Not all patients with chronical painful THA will undergo revision surgery. Consequently, in order to determine the reliable diagnostic accuracy of this test, future PJI diagnostic studies should include a second arm of "Schrödinger's hips".

어류 중 4계열 잔류 항생물질 검출을 위한 Lateral Flow Immunoassay Kit 개발 (A Lateral Flow Immunoassay Kit for Detecting Residues of Four Groups of Antibiotics in Farmed Fish)

  • 조미라;손광태;권지영;목종수;박홍제;김현용;김경동;김지회;이태식
    • 한국수산과학회지
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    • 제48권2호
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    • pp.158-167
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    • 2015
  • A lateral flow immunoassay kit based on antigen-antibody interactions was developed to detect residues of beta-lactams, quinolones, tetracyclines, and sulfonamides in farmed fish. Group-specific antibodies showing cross-reactivity with other antibiotics in the same group were produced in rabbits. The rabbits were immunized eight times to obtain the maximum titers. Antibodies were extracted from the antisera collected from the immunized rabbits and produced group-specific reactions with antibiotics from the four groups. A kit was prepared that optimize conditions for the antigen-antibody reaction, using colloidal gold conjugated antibodies, and was designed to detect the four groups of antibiotics simultaneously. The kit enabled the detection of antibiotics in the four groups at below maximum residue limits (MRLs), which were $200{\mu}g/kg$ for tetracyclines, $100{\mu}g/kg$ for sulfonamides, $50{\mu}g/kg$ for beta-lactams, and $100{\mu}g/kg$ for quinolones. The cross-reactivity of the antibodies ranged from 10-80% for the sulfonamides, 20-100% for tetracyclines, 38-100% for quinolones, and 20-100% for the beta-lactams, confirming that the antibodies were group specific. The test kit was used 30 times to examine spiked antibiotics at the limits of detection (LODs) and all produced positive results, indicating high sensitivity. The LODs for the assay ranged from 4-20 ng/mL for beta-lactams, 25-50 ng/mL for sulfonamides, 20-100 ng/mL for tetracyclines, and 30-80 ng/mL for quinolones, and there were no false negative reactions at above these LODs. In addition, all of the LODs of the developed kit were correlated with high-performance liquid chromatography (HPLC) data. Our lateral flow immunoassay kit can simultaneously detect antibiotic residues from a large number of fish samples rapidly, strengthening the safety of domestic farmed and imported fish.

STRUCTURAL INTEGRITY EVALUATION OF NUCLEAR FUEL WITH REDUCED WELDING CONDITIONS

  • Park, Nam-Gyu;Park, Joon-Kyoo;Suh, Jung-Min;Kim, Kyu-Tae;Jeon, Kyeong-Lak
    • Nuclear Engineering and Technology
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    • 제41권3호
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    • pp.347-354
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    • 2009
  • Welding is required for a connection between two different components in the nuclear fuel of a pressurized water reactor. This work relies on a mechanical experiment and analytic results to investigate the structural integrity of nuclear fuel in a situation where some components are not welded to each other. A series of lateral vibration tests are performed in a test facility, and the test structures are examined in terms of dynamic behavior. In the tests, the displacement signal at every grid structure that sustains fuel rods is measured and processed to identify the dynamic properties. The fluid-elastic stability of the structure is also analyzed to evaluate susceptibility to a cross flow with an assumed conservative cross flow distribution. The test and analysis results confirm that the structural integrity can be maintained even in the absence of some welding connections.