• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2010년 춘계학술대회논문집
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• pp.530-533
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• 2010

This paper presents numerical analysis and design optimization of various turbine blade cooling techniques with three-dimensional Reynolds-averaged Navier-Stokes(RANS) analysis. The fluid flow and heat transfer have been performed using ANSYS-CFX 11.0. A fan-shaped hole for film-cooling has been carried out to improve film-cooling effectiveness with the radial basis neural network method. The injection angle of hole, lateral expansion angle of hole and ratio of length-to-diameter of the hole are chosen as design variables and spatially averaged film-cooling effectiveness is considered as an objective function which is to be maximized. The impingement jet cooling has been performed to investigate heat transfer characteristic with geometry variables. Distance between jet nozzle exit and impingement plate, inclination of nozzle and aspect ratio of nozzle hole are considered as geometry variables. The area averaged Nusselt number is evaluated each geometry variables. A rotating rectangular channel with staggered array pin-fins has been investigated to increase heat transfer performance ad to decrease friction loss using KRG modeling. Two non-dimensional variables, the ratio of the eight diameter of the pin-fins and ratio of the spacing between the pin-fins to diameter of the pin-fins selected as design variables. A rotating rectangular channel with staggered dimples on opposite walls are formulated numerically to enhance heat transfer performance. The ratio of the dimple depth and dimple diameter are selected as geometry variables.

• 대한토목학회논문집
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• 제9권1호
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• pp.53-62
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• 1989

점변일차원이층류(漸變一次元二層流)모델로서의 염수(塩水)쐐기형상(形狀)의 계산(計算)을 행함에 있어서 필요(必要)한 계면저항계수(界面低抗係數)의 평가수단(評價手段)에 대(對)하여 논(論)한다. 예(例)를 들면, 폭(幅)이 좁은 실험수로(實驗水路)에서 얻어진 염수(塩水)쐐기의 형상(形狀)에 의해 계면저항계수(界面低抗係數)를 역산(逆算)하는 경우는 실제(實際)의 하천(河川)에서는 무시(無視)할 수 있는 수로(水路)의 측벽(側壁)의 영향(影響)을 보정(補正)하지 않으면 안된다. 본연구(本硏究)에서는 이러한 점(點)을 고려(考慮), 정상(定常) 염수(塩水)쐐기의 형상(形狀) 및 계면저항계수(界面低抗係數)에 미치는 수로(水路)의 측벽(側壁)의 영향(影響)을 밝힌다.

• Clinical and Experimental Pediatrics
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• 제58권6호
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• pp.218-223
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• 2015

Purpose: Idiopathic scoliosis is a structural lateral curvature of the spine of unknown etiology. The relationship between degree of spine curvature and cardiopulmonary function has not yet been investigated. The purpose of this study was to determine the association between scoliosis and cardiopulmonary characteristics. Methods: Ninety children who underwent preoperative pulmonary or cardiac evaluation at a single spine institution over 41 months were included. They were divided into the thoracic-dominant scoliosis (group A, n=78) and lumbar-dominant scoliosis (group B, n=12) groups. Scoliosis severity was evaluated using the Cobb method. In each group, relationships between Cobb angles and cardiopulmonary markers such as forced vital capacity (FVC), forced expiratory volume in one second ($FEV_1$), $FEV_1$/FVC, left ventricular ejection fraction, pulmonary artery flow velocity, and tissue Doppler velocities (E/E', E'/A') were analyzed by correlation analysis linear regression. Results: In group A, 72 patients (92.3%) underwent pulmonary function tests (PFTs), and 41 (52.6%) underwent echocardiography. In group B, 9 patients (75.0%) underwent PFT and 8 (66.7%) underwent echocardiography. Cobb angles showed a significant negative correlation with FVC and $FEV_1$ in group A (both P<0.05), but no such correlation in group B, and a significant negative correlation with mitral E/A ratio (P<0.05) and tissue Doppler E'/A' (P<0.05) in group A, with a positive correlation with mitral E/A ratio (P<0.05) in group B. Conclusion: Pulmonary and cardiac function was significantly correlated with the degree of scoliosis in patients with thoracic-dominant scoliosis. Myocardial diastolic function might be impaired in patients with the most severe scoliosis.

• Computers and Concrete
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• 제1권3호
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• pp.325-354
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• 2004

Slabs in buildings and bridge decks, which are restrained against lateral displacements at the edges, have ultimate strengths far in excess of those predicted by analytical methods based on yield line theory. The increase in strength has been attributed to membrane action, which is due to the in-plane forces developed at the supports. The benefits of compressive membrane action are usually not taken into account in currently available design methods developed based on plastic flow theories assuming concrete to be a rigid-plastic material. By extending the existing knowledge of compressive membrane action, it is possible to design slabs in building and bridge structures economically with less than normal reinforcement. Recent research on building and bridge structures reflects the importance of membrane action in design. This paper describes the finite element modelling of membrane action in reinforced concrete slabs through optimisation of a simple concrete model. Through a series of parametric studies using the simple concrete model in the finite element simulation of eight fully clamped concrete slabs with significant membrane action, a set of fixed numerical model parameter values is identified and computational conditions established, which would guarantee reliable strength prediction of arbitrary slabs. The reliability of the identified values to simulate membrane action (for prediction purposes) is further verified by the direct simulation of 42 other slabs, which gave an average value of 0.9698 for the ratio of experimental to predicted strengths and a standard deviation of 0.117. A 'deflection factor' is also established for the slabs, relating the predicted peak deflection to experimental values, which, (for the same level of fixity at the supports), can be used for accurate displacement determination. The proposed optimised concrete model and finite element procedure can be used as a tool to simulate membrane action in slabs in building and bridge structures having variable support and loading conditions including fire. Other practical applications of the developed finite element procedure and design process are also discussed.

• 한국터널지하공간학회 논문집
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• 제8권4호
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• pp.355-363
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• 2006

본 연구에서는 연약한 지반에 속하는 모래지반과 풍화토가 터널상부에 존재하며 연암층에 위치하는 해저터널을 대상으로 터널 배면의 간극수압이 터널의 안정성에 미치는 영향을 분석하였다. 이를 위해 비배수 조건과 배수조건을 가정하여 연계해석을 수행하였다. 비배수 터널의 경우에도 숏크리트 두께를 달리하여 안정성을 비교하였으며, 배수 터널의 경우는 숏크리트의 투수계수와 공극률을 달리하여 민감도분석을 수행하였다. 해저터널의 안정성은 유광호 등(2000, 2001, 2005)에 의해 제안된 전단강도감소 기법을 사용하여 수치적으로 구해지는 안전율을 사용하였다. 본 연구에서는 수리-역학적 연계해석 시 시공단계별 정상류 상태를 먼저 재현하고 터널의 안전율을 구했다. 연구결과 터널내로의 지하수 유입량을 어느 정도 허용함으로써 오히려 터널의 안정성이 높아짐을 확인할 수 있었다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7409-7414
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• 2015

Loop-mediated isothermal amplification (LAMP) developed by Notomi et al. (2000) has made it possible to amplify DNA with high specificity, efficiency and rapidity under isothermal conditions. The ultimate products of LAMP are stem-loop structures with several inverted repeats of the target sequence and cauliflower-like patterns with multiple loops shaped by annealing between every other inverted repeats of the amplified target in the similar strand. Because the amplification process in LAMP is achieved by using four to six distinct primers, it is expected to amplify the target region with high selectivity. However, evaluation of reaction accuracy or quantitative inspection make it necessary to append other procedures to scrutinize the amplified products. Hitherto, various techniques such as turbidity assessment in the reaction vessel, post-reaction agarose gel electrophoresis, use of intercalating fluorescent dyes, real-time turbidimetry, addition of cationic polymers to the reaction mixture, polyacrylamide gel-based microchambers, lateral flow dipsticks, fluorescence resonance energy transfer (FRET), enzyme-linked immunosorbent assays and nanoparticle-based colorimetric tests have been utilized for this purpose. In this paper, we reviewed the best-known techniques for evaluation of LAMP amplicons and their applications in molecular biology beside their advantages and deficiencies. Regarding the properties of each technique, the development of innovative prompt, cost-effective and precise molecular detection methods for application in the broad field of cancer research may be feasible.

• Nuclear Engineering and Technology
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• 제24권3호
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• pp.263-273
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• 1992

핵연료 집합체의 속도분포, 압력강하는 열수력 설계와 안전해석에 중요하다. 본 실험적 연구의 목적은 봉다발 지지 격자 하류에서의 수력학적 혼합을 고찰하는데 있다. 이 연구에서 가압경수로형 5X5 봉다발 부수로의 상세한 수력학적 특성들을 1차익 He-Ne LDV를 이용하여 측정하였다. 축방향 유속, 난류강도와 압력강하를 주로 측정하였고 LDV의 정렬을 조정하여 측방향의 유속, 난류강도, Reynolds 전단응력 등도 역시 측정하였다. 봉다발의 마찰계수와 지지 격자의 손실계수는 측정된 압력 강하로부터 평가하였다. 서로 다른 종류의 지지 격자의 수력학적 혼합성능을 이웃하는 부수로 간에서의 난류 횡류 혼합률을 예측함으로써 고찰할 수 있었다.

• Archives of Reconstructive Microsurgery
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• 제12권1호
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• pp.19-29
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• 2003

Soft tissue reconstruction of dorsum of the foot and ankle has long presented challenging problems for the reconstructive surgeon. Limitations of available local tissue, the need for specialized tissue, and donor site morbidity restrict the options. In an effort to solve these difficult problems, we have begun to use adipofascial flap based on the perforating branch of the peroneal artery. We present our early experience of 5 patients treated with this flap. Our patients ranged from 6 to 26 years in age and included 3 males and 2 females. The etiologies of the wounds were secondary to traffic accident, and crushing injury. The flaps had reverse flow in all patients. The flap and the adjoining raw area were covered with a full-thickness skin graft, while the donor site at the lateral aspect of the leg was closed primarily without grafting. The skin graft was taken from the inguinal area, which was closed primarily. Compared with other flap, this adipofascial flap is thinner, producing less bulkiness to the recipient site and minor aesthetic sequelae to the donor site. In our opinion, this flap is versatile, effective, and an addition to the armamentarium of the reconstructive surgeon for coverage of difficult wounds of the foot and ankle.

• Archives of Reconstructive Microsurgery
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• 제20권1호
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• pp.51-56
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• 2011

During below knee amputation, the amputation stump must be covered with well-vascularized and sensate soft tissue. Many flaps can be used for this purpose, but available reconstructive options are limited. We performed reverse flow ALT flap elevation on two patients with below knee amputations to reconstruct defects in the stumps. The sizes of the defects in the stumps were $4{\times}16$ cm and $5{\times}5$ cm, respectively. The most distal portion of the defects were located 20 cm and 16 cm lateral to the knee joint in a curve, respectively. The size of the elevated flap was $5{\times}18$ cm for case 1 and $18{\times}10$ cm for case 2. The respective pivot points of the pedicles were 7 cm and 6 cm above the patella and the respective lengths of the pedicles were 17 cm and 16 cm. In both cases, venous congestion occurred on the second postoperative day and the flap distal to 10 cm or more from below the knee joint was necrotized at the second postoperative week. Surgeons should be cautious when using a reverse ALT flap to reconstruct a soft tissue defect located 10 cm or more distal from below the knee joint. Since a pedicle longer than 15 cm may develop partial necrosis of the flap, simultaneous application of antegrade venous drainage is recommended.

• 한국펄프종이공학회:학술대회논문집
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• 한국펄프종이공학회 2006년도 PAN PACIFIC CONFERENCE vol.1
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• pp.147-152
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• 2006

Restoration of historical documents and arts has become important to inherit cultural properties. Most of historical documents were recorded on paper. Therefore, restoration of ancient papers is demanded and techniques for this purpose must be developed and sophisticated. In our study, several nondestructive methods for analyzing ancient paper have been developed. Image analysis using fast Fourier transform with suitable modifications was applied to optical micrographs of traditionally-handmade Korean and Japanese papers. This analysis determines the angle and anisotropy of fiber orientation of paper surfaces. Fiber orientation of traditionally-handmade Korean and Japanese papers was found to show their own characteristics in accordance with the motion of a papermaking screen made of bamboo splints. Consequently, the information on fiber orientation was found to be possible to distinguish the flow-sheet forming typical of Japanese paper and still-sheet forming typical of Korean paper. Moreover, the anisotropy was always higher for the screen side than for the top side, thus meaning that surface fiber orientation is possible to distinguish the two sides of paper of which papermaking history is unknown. An application of this technique to actual historical documents evidenced that wrapping papers were used as envelops with a lateral side up, namely, after rotating 90 degrees. A variety of cultural habits in writing letters was revealed by discrimination of the two sides.