• BMB Reports
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• 제40권2호
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• pp.156-162
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• 2007

Two lysis-defective but DNA synthesis non-defective temperature-sensitive (ts) mutants of mycobacteriophage L1, L1G23ts23 and L1G25ts889 were found to be defective also in phage-specific RNA synthesis in the late period of their growth at 42$^{\circ}C$each to the extent of 50% of that at 32$^{\circ}C$The double mutant, L1G23ts23G25ts889 showed the ts defect in phage RNA synthesis that was nearly additive of those shown individually by the two single-mutant parents. Both G23 and G25 were shown to start functioning sometimes between 30 and 45 min after infection but the former gene might be dispensable after 45 min, while the latter was not. Northern analysis also shows that at 42$^{\circ}C$>, L1G23ts23 affects RNA synthesis more strongly than L1G25ts889 from L1 DNA segments that serve as the template for late gene transcription. Among the 21 virion and 12 non-virion late proteins synthesized by L1, L1G23ts23 is defective in the synthesis of at least 9 virion and all of non-virion proteins at 42$^{\circ}C$>. In contrast, L1G25ts889 is completely defective in synthesis of all the 33 late proteins. Possible roles of G23 and G25 in the positive regulation of transcription of different sets of late genes of L1 have been discussed.

• 한국초지조사료학회지
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• 제20권3호
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• pp.161-168
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• 2000

The experiment was carried out to investigate the effect of extension of grazing duration in late autumn on grass growth in following spring, in order to improve the rate of self-sufficiency for roughage feed. Plant height, total biomass and litter production of herbage were increased when the grazing was finished early in late autumn. The proportions of clover and litter, and amounts of animal intake were decreased, with extended grazing duration in late autumn. But when the grazing was finished late in autumn, the contents of crude protein (CP, %) of herbage were increased, contents of acid detergent fiber (ADF, %), neutral detergent fiber (NDF, %) and crude ash (%) were decreased in pasture after grazing, therefore the contents of total digestible nutrients (TDN, %) and relative feed value (RFV) of herbage were improved. The early end grazing showed that plant height, total biomass and litter production of herbage in following spring were higher than those in late end grazing. However, increased yields were not significantly different among end grazing treatments (0.12-0.15 tonha), except for the final end grazing in late autumn (0.01 tonha). With extended grazing duration in late autumn, the contents of CP of herbage in following spring were increased, contents of ADF, were decreased, and RFV were improved. (Key words : Extension of grazing duration, Plant height, Biomass, Amount of intake, Increased yield, Crude protein, TDN) rll\ulcorner c# qiil x i 9 ~ 1 a% * (College of Natural Resources, Taegu Univ., Kyongsan, 71 2-714, Korea) * $4 4 qiil 34 qq(Co1lege of Liberal Arts & Sciences, Yonsei Univ., Wonju, 220-701, Korea) '* 8 * jL@%ft@ &@%(Faculty of Agriculture, Hokkaido Univ., Sapporo, 060 Japan)

• Human Ecology Research
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• 제52권6호
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• pp.639-649
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• 2014

The main purpose of this study was to find the relationship between the delinquency-onset time in the source and the continuity of delinquency. In order to achieve this objective, we divided 350 first-year high school students into three groups early-onset type, late-onset type, and non-delinquent adolescents on the basis of the delinquency onset. The results of this study were as follow: (1) for the boys, the early-onset type shows a higher continuity of delinquency than both the late-onset type and the general adolescents. On the other hand, for the girls, the early-onset type shows a higher continuity of delinquency than the late-onset type, but there was no difference in the persistence duration between the late-onset type and the non-delinquent adolescents. (2) For the boys, the examination reveals that the early-onset type has a higher degree of sensation seeking and impulsivity than the general adolescents. In addition, the early-onset type shows a higher degree of sensation seeking than the late-onset type, whereas the two show no difference in impulsivity. For the girls, sensation seeking did not show any difference depending on the delinquency onset. However, more impulsivity appeared in the early-onset type than in the late-onset type or the non-delinquent adolescents. (3) The relative priorities of variables determining the group to which the students belong on the basis of the delinquency onset are in the order of sensation seeking and juvenile impulsivity. Therefore, this study, suggests that the early-onset type requires a different kind of intervention than the late-onset type.

• Asian Pacific Journal of Cancer Prevention
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• 제14권7호
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• pp.4373-4377
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• 2013

Background: The majority of cervical cancers, the most prevalent cancer among Nepali women, are diagnosed in advanced stage leading to high mortality in Nepal. The present study explored factors associated with late diagnosis. Materials and Methods: A cross-sectional study was carried out in two specialized cancer hospitals of Nepal from August 12 to October 12, 2012. Randomly selected 110 cervical cancer patients were interviewed and their medical records were reviewed. Multivariate logistic regression analysis was performed to predict associations. Results: Mean age of patients was 52.7years (SD=10.6), 66% were illiterate and 77% were rural inhabitants. Medical shops (33.6%) and private hospitals (31%) were major first contact points of patients with health care providers (HCP). There was no cervical/per-speculum examination (78.2%) and symptoms misinterpretation (90%) of patients occurred in initial consultation with HCP. Four in every five cases (80.9%) of cervical cancer had late diagnosis. Literate women (adjusted OR=0.121, CI: 0.030-0.482) and women having abnormal vaginal bleeding as early symptom (adjusted OR=0.160, CI: 0.035-0.741) were less likely to suffer late diagnosis. Women who shared their symptoms late (adjusted OR=4.272, CI: 1.110-16.440) and did so with people other than their husband (adjusted OR=12.701, CI: 1.132-142.55) were more likely for late diagnosis. Conclusions: High level of illiteracy among women and their problematic health seeking behavior for gynecological symptoms are responsible for late diagnosis of cervical cancer in Nepal. In the absence of a routine screening program, prevention interventions should be focused on raising awareness of gynecological symptoms and improving health seeking behavior of women for such symptoms.

• 한국초지조사료학회지
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• 제16권2호
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• pp.161-168
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• 1996

This experiment was canied out to determine the effect of cultivar, harvest date and drying method on the changes of moisture content and quality of spring harvest oat(Avena sativa L.) hay. Disign of the experiment was a spilt-split-plot arrangement with early and late cultivars as main plots, early and late harvest dates as sub-plots, and drying agent and tedding as sub-subplots in three replications. Moisture content of early harvest oat was higher than that of late harvest oat by 127.1% dry weight(DW) in 'Swan' and 39.8%DW in 'Foothill'. Moisture content difference between 'Foothill' and 'Swan' was 117.6%DW at early and 204.9%DW at late harvest dates, respectively. Cultivar effect on moisture content of cut oat was higher at late harvest date, but drying method effect was higher at early harvest. Total nitrogen content of early harvest was higher than that of late harvest by 0.70% and that of 'Foothill' was higher than that of 'Swon' by 0.86%. But no difference in total nitrogen content was found between the drying method. ADF and NDF contents were increased at late harvest by 29% and 1 I%, respectively(P<0.05). ADF and NDF contents of 'Swan' were higher than those of 'Foothill' by 2.8% and 4.5%, respectively. No difference in ADF and NDF contents was obtained by drying methods. RFV of early harvest oat hay was 95.1 and 103.8 for 'Swan' and 'Foothill' but late harvest 'Swan' and 'Foothill' showed 74.8 and 85.0, respectively.

• 한국의사학회지
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• 제25권2호
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• pp.1-10
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• 2012

The late Goryeo and Early Joseon period marks the development of Hyang-yak medicine in medical history in Korea. There have been not a few outcomes in organizing Hyang-yak medicine through the hitherto research works, but there has hardly any attempt to view the medicine in the late Goryeo and Early Joseon period from a different standpoint besides Hyang-yak. This writer, in the middle of doing research on 'Book for Alimentotherapy' named "Sikuisikgam", came to know that not a few parts of this book were quoted in a large volume of "Biebaekyobang" in the late Goryeo, "Hyangyakjipseongbang" which compiled the early Joseon Hyangyak medicine, "Uibangyuchi" which wrapped up the medical knowledge in East Asia before the early Ming Dynasty, and "Sikryochangyo" which was a representative book for alimentotherapy in the early period of Joseon Dynasty. The reason that the representative medical books written in the period of Late Goryeo and Early Joseon thought much of the knowledge contained in "Sikuisikgam" is that they showed a great concern for prevention and treatment of diseases through alimentotherapy. When we say that Hyangyak medicine, which has provided the Late Goryeo and Early Joseon medicine, bases its standard on 'Regionality' and 'Properties of Medicinal ingredients', then alimentotherapy puts its focus on a 'Remedial method' itself. As for food, they might have given priority to the food that was easy to get nearby, so there is no way for alimentotherapy but to have the realm which is overlapped with Hyangyak medicine in some measure, That's the very reason why alimentotherapy has remained inseparate from Hyangyak medicine. Through 'Alimentotherapy' and Late Goryeo and Early Joseon medical books, this writer thinks that it might be possible for us to take a view of the Late Goryeo and Early Joseon not only from the perspective of Hyangyak medicine but also from a new perspective of so-called alimentotherapy.

• 한국수학교육학회지시리즈E:수학교육논문집
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• 제32권4호
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• pp.519-536
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• 2018

본 연구는 후기성인학습자를 위한 수리문해 프로그램 개발 연구이다. 이를 위하여 먼저, 수리문해의 성격을 조명하고 이를 통해 후기성인학습자들을 위한 수리문해 학습 내용을 선정하였다. 또한 선별한 수학 내용을 후기성인학습자의 경험에 기반한 실생활과 연관 지어 교수학습 자료를 개발하였다. 이러한 수리문해 프로그램을 후기성인학습자들에게 적용한 결과 학습초기 흥미와 같은 정의적 영역의 변화를 동반하며 학습이 지속됨에 따라 수학적 정형화 단계를 거쳐 수학적 정교화가 발현되는 양상을 관찰할 수 있었다. 본 연구는 후기성인들의 경험에 기반하여 후기성인을 위한 산술을 수리문해 측면에서 재정의함으로서, 비형식적인 후기성인학습자들의 문제해결과정을 정교한 수학적 문제해결 해결로 정당화시킬 수 있도록 후기성인학습자의 수학적 정교화에 기여할 수 있었다는 점에서 그 의의가 있다.

• 한국수학사학회지
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• 제13권2호
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• pp.145-150
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• 2000

This paper is intended to show that fuzzy logic can be understood in the context of the late Wittgenstein's philosophy. It introduces the view of language presupposed by fuzzy logic and parallels it with the late Wittgenstein's view of language. To make the parallel clear it contrasts the views of the early Wittgenstein and the late Wittgenstein.

• 한국잠사곤충학회지
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• 제40권1호
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• pp.60-62
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• 1998

To understand expression of some early and late genes of Bombyx mori nuclear polyhedrosis virus (BmNPV) in the B. mori-derived BmN cell line, the transcripts were analyzed by polymerase chain reaction with synthetic primers. After infection, the transcript of early genes, which include p35, IE1 and helicase p143, was immediately detected in the infected cells. In addition, the transcript of late genes, which include p10 and polyhedrin, was also detected in just-infected cells. In conclusion, our results revealed that transcripts of early and late genes of BmNPV are immediately expressed from the cells after infection.

• 대한조선학회논문집
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• 제48권5호
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• pp.414-420
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• 2011

Decades of studies of geophysical flow have unveiled that the flow downstream of obstacles in stratified flow consists of attached wake and strong gravity waves, or separated, fluctuating wake and persistent late wakes. Among unique and interesting characteristics of the stratified flow past obstacles is the generation of coherent vortex in the late wake far downstream of the object. Unlike in homogeneous fluid, the flow field downstream self-develops coherent vortex even after diminishing of the near wake, no matter how small the stratification is. This paper present a computational approach to simulate the generation of the coherent vortex structure in the late wake of a moving sphere submerged in weakly stratified fluid. The results are in consistent with several experimental observations and the vortex stretching mechanism is employed to explain the process of coherence.