• The Korean Journal of Nuclear Medicine Technology
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• v.14 no.1
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• pp.90-93
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• 2010

Purpose: In our nuclear medicine department, we suggested AMC RBC labeling method improved by modifying a part of existing modified in-vitro method to raise the efficiency of $^{99m}Tc$-RBC labeling. However, it needs to be more additional time and efforts than existing modified in-vitro method because the AMC RBC labeling method has to carry out the centrifugal separation process for 3~5 minutes. Therefore, in this study, we conducted researches to aim to maintain stable labeling effects and supplement a problem about additional time by reducing rotating time when labeling $^{99m}Tc$-RBC. Materials and Methods: This research has been conducted the object of 30 patients who examined study using $^{99m}Tc$-RBC and agreed to this research at our hospital from May 2009 to September 2009. We made 4 blood samples which consisted of ACD 1 cc along with 5 cc blood from each patient and used the AMC RBC labeling method. At this moment, each labeling efficiency was calculated by different rotating time 5 min, 10 min, 15 min, and 20 min and then we compared differences. Results: As a result, When comparing the $^{99m}Tc$-RBC labeling method efficiency by using the AMC RBC labeling method which differents from rotating time, each labeling efficiency were $92.3{\pm}5.0%$ in 5 min, $95.9{\pm}5.0%$ in 10 min, $97.4{\pm}4.9%$ in 15 min and $97.7{\pm}4.8%$ in 20 min. We analyzed differences of the labeling efficiency from change of rotating time by using an one-way ANOVA and verified that in Duncan method. There was relatively efficiency low in 5min rotating time and no statistically significant change in over. Conclusions: When comparing a existing method, the AMC RBC labeling method which goes through the centrifugal separation process again offers more favorable condition to combine RBC with $^{99m}TcO4^-$ by eliminating an plasma ingredient. When using the modified in-vitro method, we have almost 20 min to rotate to acquire stable labeling efficiency. But, when using the AMC RBC labeling method, we acquire labeling efficiency well what we want within only 10 min to rotate. Decrease of rotating time can complement the AMC RBC labeling method which goes through the centrifugal separation process again and also provide more rapid study such as G-I bleeding study due to fast labeling.

• 제어로봇시스템학회:학술대회논문집
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• 1996.10b
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• pp.1280-1283
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• 1996

The labels are used for products configuration of the labeling in hot coil. Robot system is constructed to labeling in hot coils automatically, so we achieve the confidence of labeling work and the promotion of operation efficiency.

• The Korean Journal of Nuclear Medicine Technology
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• v.16 no.2
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• pp.131-134
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• 2012

Purpose : The labeling efficiency of radiopharmaceuticals in nuclear medicine is important in terms of accuracy and reliability of the examination. Usually $^{99m}Tc$-HMPAO used for brain SPECT scan is chemically unstable since lots of impurities are existing. Therefore, occurrence of loss of labeling efficiency is easy to appear. In this paper, labeling and use of $^{99m}Tc$-HMPAO should be helpful through experiments on factors affecting the labeling efficiency of $^{99m}Tc$-HMPAO. Materials and Methods : Domestic HMPAO vials (Dong-A) used for brain SPECT scan were tested. Domestic Samyeong Generator 55.5 GBq (1,500 mCi), TLC measurement sets (ITLC-SG, butanone, saline, TLC chamber) and radio-TLC scanner (Advantest, Bioscan) were used. In the first experiment, after eluting generator at 1, 8, 16, 24, 28 hours apart, each eluted $^{99m}Tc$-pertechnetate were labeled with HMPAO and the labeling efficiency was measured. In the second experiment, after eluting $^{99m}Tc$-pertechnetate from a generator, $^{99m}Tc$-pertechnetate was drawn at 0, 1, 3, 6 hours. And each drawn $^{99m}Tc$-pertechnetate were labeled with HMPAO for measuring labeling efficiency. In the third experiment, labeling efficiency was measured at 0, 0.5, 3, 5, 7 hours after labeling $^{99m}Tc$-HMPAO. Results : In the first experiment, measured values were appeared 95.05, 94.64, 94.94, 95.64, 96.76% in passing order of time. In the second experiment, measured values were appeared 94.38, 94.23, 93.26, 91.03% in passing order of time. In the third experiment, measured values were appeared 95.76, 94.17, 88.19, 83.6, 76.86% in passing order of time. Conclusion : In the first experiment of this paper, labeling efficiency of $^{99m}Tc$-HMPAO labeled with $^{99m}Tc$-pertechnetate eluted after 24 hours from first elution. Additional experiments will be needed to discuss for usability. In the second experiment, the labeling efficiency was slightly decreased in chronological order, but it was measured higher than 90%. Also, additional experiments will be needed to discuss for usability. In the third experiment, the labeling efficiency was decreased considerably. Especially, within 3 hours after the labeling is recommended to use $^{99m}Tc$-HMPAO

• Journal of KIISE:Databases
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• v.36 no.2
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• pp.150-167
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• 2009

XML has become the new standard for storing, exchanging, and publishing of data over both the internet and the ubiquitous data stream environment. As demand for efficiency in handling XML document grows, labeling scheme has become an important topic in data storage. Recently proposed labeling schemes reflect the dynamic XML environment, which itself provides motivation for the discovery of an efficient labeling scheme. However, previous proposed labeling schemes have several problems: 1) An insertion of a new node into the XML document triggers re-labeling of pre-existing nodes. 2) They need larger memory space to store total label. etc. In this paper, we introduce a new labeling scheme called a Circle Labeling Scheme. In CLS, XML documents are represented in a circular form, and efficient storage of labels is supported by the use of concepts Rotation Number and Parent Circle/Child Circle. The concept of Radius is applied to support inclusion of new nodes at arbitrary positions in the tree. This eliminates the need for re-labeling existing nodes and the need to increase label length, and mitigates conflict with existing labels. A detailed experimental study demonstrates efficiency of CLS.

• Journal of the Korean Institute of Intelligent Systems
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• v.21 no.1
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• pp.138-144
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• 2011

L(2, 1)-labeling problem of a graph G = (V, E) is a problem to find an efficient way to distribute radio frequencies to various wireless equipments in wireless networks. In this work, we suggest a Simulated Annealing algorithm that can be applied to the L(2, 1)-labeling problem. By applying the suggested algorithm to various graphs we will try to show the efficiency of our algorithm.

• Reproductive and Developmental Biology
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• v.35 no.4
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• pp.503-510
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• 2011

Cellular uptake of nanoparticles for stem cell labeling and tracking is a critical technique for biomedical therapeutic applications. However, current techniques suffer from low intracellular labeling efficiency and cytotoxic effects, which has led to great interest in the development of a new labeling strategy. Using silica-coated nanoparticles conjugated with rhodamine B isothiocyanate (RITC) (SR), we tested the cellular uptake efficiency, biocompatibility, proliferation or differentiation ability with murine bone marrow derived hematopoietic stem/progenitor cells. The bone marrow hematopoietic cells showed efficient uptake with SR with dose or time dependent manner and also provided a higher uptake on hematopoietic stem/progenitor cells. Biocompatibility tests revealed that the SR had no deleterious effects on cell cytotoxicity, proliferation, or multi-differentiation capacities in vitro and in vivo. SR nanoparticles are advantageous over traditional labeling techniques as they possess a high level of cellular internalization without limiting the biofunctionality of the cells. Therefore, SR provides a useful alternative for gene or drug delivery into hematopoietic stem/progenitor cells for basic research and clinical applications.

• Journal of Energy Engineering
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• v.23 no.3
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• pp.58-65
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• 2014

The study examined the post-monitoring programs under the energy efficiency labeling program in developed countries. This study suggests a few solutions to improve the post-monitoring activities under the program. First, samples should be selected from each category for the post-monitoring activities, taking account of the consumer's continuous buying behavior. Second, it is necessary to check of detailed label contents and to perform the frequent monitoring the reinforcement of the measurement of items which have violated labeling more than once over the past few years. Last, this study suggests that the entire post-monitoring process should be disclosed and be posted on the websites on the internet in general.

• Journal of The Korean Radiological Technologist Association
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• v.30 no.1
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• pp.63-69
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• 2004

Purpose : We underwent this study to evaluate the factors which influence labelling efficiency when modified in vivo erythrocyte labeling technique was used. Materials and methods : Thirty healthy volunteers (M : F = 19 : 11, age : 25$\pm$2yrs)

• BMB Reports
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• v.28 no.5
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• pp.433-436
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• 1995

In order to assign NMR signals, conditions for the specific labeling of cytochrome $c_3$ of D. vulgaris Miyazaki F through the culture in a minimal medium were established. Phenylalanine residue was specifically deuterated at more than 85% efficiency. Cytochrome $c_3$ has two phenylalanine residues. The signals of one phenylalane were missing and this was tentatively assigned to Phe20.

• Journal of Energy Engineering
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• v.24 no.2
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• pp.179-186
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• 2015

This study suggests a few solutions to improve the post-monitoring activities under the Energy Efficiency Labeling Program. First, samples should be selected from each category for the post-monitoring activities, taking account of the consumer's continuous buying behavior, while it is also important to form and operate a deliberation committee. Second, it is necessary to alleviate the checking process of the label content of 9 items which have never been violated the labeling regulation since 2005. This study suggests the detailed checking of label contents and the reinforcement of the measurement of 17 items which have violated labeling more than once over the past few years. Third, this study suggests that the entire post-monitoring process should be disclosed and be posted on the websites of related agencies and on the Internet in general.