• Title/Summary/Keyword: kyushu

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Efficacy and Safety of an Increased-dose of Dexamethasone in Patients Receiving Fosaprepitant Chemotherapy in Japan

  • Kumagai, Hozumi;Kusaba, Hitoshi;Okumura, Yuta;Komoda, Masato;Nakano, Michitaka;Tamura, Shingo;Uchida, Mayako;Nagata, Kenichiro;Arita, Shuji;Ariyama, Hiroshi;Takaishi, Shigeo;Akashi, Koichi;Baba, Eishi
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.1
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    • pp.461-465
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    • 2014

  • Background: Antiemetic triplet therapy including dexamethasone (DEX) is widely used for patients receiving highly emetogenic chemotherapy (HEC). In Japan, the appropriate dose of DEX has not been established for this combination. Materials and Methods: To assess the efficacy and safety of increased-dose DEX, we retrospectively examined patients receiving HEC with antiemetic triplet therapy. Results: Twenty-four patients (fosaprepitant group) were given an increased-dose of DEX (average total dose: 45.8mg), fosaprepitant, and 5-HT3 antagonist. A lower-dose of DEX (33.6mg), oral aprepitant, and 5-HT3 antagonist were administered to the other 48 patients (aprepitant group). The vomiting control rates in the fosaprepitant and aprepitant groups were 100% and 85.4% in the acute phase, and were 75.0% and 64.6% in the delayed phase. The incidences of toxicity were similar comparing the two groups. Conclusions: Triplet therapy using an increased-dose of DEX is suggested to be safe and effective for patients receiving HEC.

  • https://doi.org/10.7314/APJCP.2014.15.1.461 인용 PDF KSCI

Typhoon damage analysis of transmission towers in mountainous regions of Kyushu, Japan

  • Tomokiyo, Eriko;Maeda, Junji;Ishida, Nobuyuki;Imamura, Yoshito
    • Wind and Structures
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    • v.7 no.5
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    • pp.345-357
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    • 2004

  • In the 1990s, four strong typhoons hit the Kyushu area of Japan and inflicted severe damage on power transmission facilities, houses, and so on. Maximum gust speeds exceeding 60 m/s were recorded in central Kyushu. Although the wind speeds were very high, the gust factors were over 2.0. No meteorological stations are located in mountainous areas, creating a deficiency of meteorological station data in the area where the towers were damaged. Since 1995 the authors have operated a network for wind measurement, NeWMeK, that measures wind speed and direction, covering these mountainous areas, segmenting the Kyushu area into high density arrays. Maximum gusts exceeding 70 m/s were measured at several NeWMeK sites when Typhoon Bart (1999) approached. The gust factors varied widely in southerly winds. The mean wind speeds increased due to effects of the local terrain, thus further increasing gust speeds.

  • https://doi.org/10.12989/was.2004.7.5.345 인용