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Effects of Pine Needle Extract Oil on Blood Glucose and Serum Insulin Levels in db/db Mice (2형 당뇨 마우스에서 솔잎 추출용액의 경구투여가 혈당조절에 미치는 영향)

  • Kim, Mi-Joung;Ahn, Jin-Hong;Choi, Kang-Ho;Lee, Yun-Hak;Woo, Gyeong-Jin;Hong, Eun-Kyung;Chung, Young-Shin
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.3
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    • pp.321-327
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    • 2006
  • This study was performed to investigate the hypoglycemic effect of pine needle extract oil against type 2 diabetes. Six-week-old male C57BL/Ks(db/db) mice were divided into four groups : negative control, pine needle extract oil low dose, high dose and positive control groups, which fed daily for 6 weeks with corn oil, pine needle extract oil 112.5 mg/kg, 450 mg/kg or metformin (150 mg/kg ), respectively. The oral administration of the pine needle extract oil resulted in the significant and dose-dependent decreases of blood glucose levels in comparison with corn oil treatment. The levels of HbAlc showed a tendency of the decrease by the high dose treatment of the pine needle extract oil and were positively correlated with blood glucose levels (r=0.5046, p=0.0023) . However, the levels of serum insulin and C-peptide were not affected by pine needle extract oil or metformin treatments. The levels of serum leptin, which is related with the insulin sensitivity, showed a tendency of the increases by pine needle extract oil treatment and were negatively correlated to blood glucose levels (r=-0.4754, p=0.0052). In conclusion, these results suggest that the pine needle extract oil have a potential for the oral anti-hyperglycemic agent and the mode of action may be related with the improvement of the insulin sensitivity through blood leptin.

Properties and Glue Shear Strength of the Water Soluble Urea-Phenol Copolymer Adhesive as a High Temperature Curing Binder for Plywood (합판용(合板用) 고온경화형(高温硬化型) 수용성(水溶性) 요소(尿素)·페놀공축합수지(共縮合樹脂)의 성질(性質)과 그 접착강도(接着強度))

  • Lee, Hwa Hyoung
    • Journal of Korean Society of Forest Science
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    • v.60 no.1
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    • pp.51-57
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    • 1983
  • Properties and glue shear strength of each water soluble rues-phenol copolymer adhesive and phenolic resin adhesive were examined as a high temperature curing binder through the manufacture of plywood made of Kapur veneer. The former has different molar ratio and the latter was made from different catalyst method. The results are summarized as follows: 1) Specific gravities of air dried plywood manufactured from each adhesive ranged from 0.67 to 0.82 and their moisture contents met the K.S. standard 2) In dry and wet shear strength, adhesives with 60 percent of non volatile content showed higher values than those with 50 percent except phenolic resin. Urea-phenol copolymer resin with 20 percent of phenol content exhibited the highest, and that with 70 percent the lowest. Filling effect of wood flour on the bonding strength is great in urea-phenol copolymer resin with more than 50 percent of phenol content, especially significant in 50 percent of non volatile content including alkali catalyst phenolic resin. Alkali and acid catalyst methods were the highest among the adhesive manufacture methods. In wet strength, urea resin belongs to the lowest group. 3) In glue shear strength after boiling and drying test, no method for manufacturing phenolic formaldehyde resin adhesive was stronger than alkali and acid catalyst methods. Phenolic resin made from alkali catalyst method needs a wood flour filler to improve the bonding quality. Urea-phenol copolymer resin with 10 percent of phenol content showed the reasonable water resistance.

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Studies on the Properties of the Fiberboard - I. Hardboard (S-1-S) from Juvenile Wood of Sycamore (Platanus orientalis L.) (섬유판(纖維板)의 재질(材質)에 관한 연구(硏究) - I. 유령(幼齡)버즘나무를 원료(原料)로 한 경질섬유판(硬質纖維板))

  • Min, Du-Sik;Shin, Dong So
    • Journal of Korean Society of Forest Science
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    • v.26 no.1
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    • pp.57-65
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    • 1975
  • This study was carried out to examine the effect of manufacturing factors on physical properties of hardboard (S.I.S) made from the juvenile wood of sycamore (Platanus orientalis L.) The results obtained may be summarized as follows: 1. The difference among the yields of pulp treated with preheat time (defibrate condition) was significant in those of treatments. There was no difference in the yield of pulp treated with defibrate time. The yields of pulp on the tree age classes were shown the difference by 2<4<6<8 years. 2. The specific gravities of hardboard that were treated with hot pressing conditions showed us significantly in those of treatments. There was no difference on the specific gravities among hardboards, treated with resin and wax contents. But in all cases of the specific gravities satisfied the standard which specified the KS F 3203 (Hardboard) 3. The moisture contents of hardboard satisfied the standard which calls for 13-percent below. There were difference in moisture contents between hardboard, treated with preheating time, resin and wax contents and hot pressing conditions. And the moisture contents of hardboard on the tree age classes showed the difference by 2<4<6<8 years. 4. The water absorption and thickness swelling of hardboard treated with defibrations, resin and wax contents, and hot pressing conditions were significant in those of treatments. And the water absorption and thickness swelling of hardboard on the tree age classes showed us the significant difference by 8<6<4<2 years. 5. The difference among the flexural strength in using tested three conditions showed us the difference by defibration$200kg/cm^2$) of hardboard, it is likely to be recommened that the juvenile wood of sycamore is valuable for the raw materials of hardboards.

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Assessment on the Content of Heavy Metal in Orchard Soils in Middle Part of Korea (중부지역 과수원 토양중의 중금속 함량 평가)

  • Jung, Goo-Bok;Kim, Won-Il;Lee, Jong-Sik;Shin, Joung-Du;Kim, Jin-Ho;Yun, Sun-Gang
    • Korean Journal of Environmental Agriculture
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    • v.23 no.1
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    • pp.15-21
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    • 2004
  • Objectives of this study were to monitor the distribution of heavy metals, to compare extractable heavy metal with total content and to investigate the relationships between soil physico-chemical properties and heavy metals in orchard soil. Sampling sites were 48 in Gyeonggi, 36 in Gangwon, 36 in Chungbuk, and 44 in Chungnam, Soils were collected farm form two depths, 0 to 20 and 20 to 40 cm (here after referred to as upper and lower layers) from March to May in 1998. Total contents of heavy metal in soils were analyzed by ICP-OES after acid digestion ($HNO_3$:HCl:$H_2O_2$) whereas extractable contents were measured after successive extraction of 0.1N-HCl, 0.05 M-EDTA, and 0.005 M-DTPA. Mercury was analysed by mercury atomizer. The average contents of Cd Cu, and Pb in the extractant with 0.1N-HCl at upper layer were 0.080, 4.23, and 3.42 mg/kg, respectively. As content in the extractant with 1N-HCl was 0.44 mg/kg, and total contents of Zn, Ni and Hg were 78.9, 16.1, and 0.052 mg/kg, respectively. The ratios of concentrations of heavy metals to threshold values (Cd 1.5, Cu 50, Pb 100, Zn 300, Ni 40, Hg 4 mg/ke in Soil Environmental Conservation Act in Korea (2001) were low in the range of $1/2.5{\sim}1/76.9$ in orchard soils. The ratios of extractable heavy metal to total content ranged $5.4{\sim}9.21%$ for Cd, $27.9{\sim}47.8%$ for Cu, $12.6{\sim}21.8$% for Pb, $15.8{\sim}20.3%$ for Zn, $5.3{\sim}6.3%$ for Ni, and $0.7{\sim}3.6%$ for Zn, respectively. Cu and Pb contents in 0.05 M-EDTA extractable solution were higher than those in the other extractable solution. Total contents of Cd, Ni and Ni in soils were negatively correlated with sand content but positively correlated with silt and clay contents. Ratios of extractable heavy metal to total content were negatively correlated with clay content but ai and Ni contents were positively correlated with soil pH, organic matter, and available phosphorous. Therefore, the orchard soil was safe because the heavy metal contents of orchard soil were very low as compared to its threshold value in the Soil Environmental Conservation Act. However, it need to consider the input of agricultural materials to the agricultural land for farming practices for assessment of heavy metals.

The Result of Rotator Cuff Repair Using Arthroscopic Margin Convergence Technique in Irreparable Large and Massive Rotator Cuff Tears (해부학적 봉합이 불가능한 회전근 개 파열에서 관절경하 모서리 맞춤 술식을 이용한 봉합의 결과)

  • Choi, Eui-Sung;Park, Kyoung-Jin;Kim, Yong-Min;Kim, Dong-Soo;Shon, Hyun-Chul;Cho, Byung-Ki;Park, Ji-Kang;Lee, Hyung-Joon
    • Clinics in Shoulder and Elbow
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    • v.14 no.1
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    • pp.46-52
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    • 2011
  • Purpose: This study was performed to assess the usefulness of non-anatomical repair for irreparable large and massive rotator cuff tears by the arthroscopic margin convergence technique. Materials and Methods: Twenty-two patients were followed up more than 1 year after non-anatomical repair for irreparable large and massive rotator cuff tears using the arthroscopic margin convergence technique. The clinical evaluation was performed according to the KSS score, the UCLA score and the Visual analogue scale (VAS). The measurement of the acromio-humeral distance was performed using the shoulder anterior-posterior radiographs. The measurement of fatty degeneration and the healing status was performed using the shoulder MRI after 6 months. Results: Among twenty-two patients, follow up MRI was performed in eleven cases. Three cases were well healed, four cases were partial healed and another four cases were re-torn. The KSS and UCLA scores had significantly improved from a preoperative average of 45.0${\pm}$8.014 and 10.8${\pm}$2.302 points to 77.1${\pm}$10.151 and 30.0${\pm}$1.521 points, respectively, and the pain VAS had decreased from a preoperative average of 7.7${\pm}$0.616 points to 3.0${\pm}$1.021 points at the last follow up. Less favorable results were obtained when the patient had a grade of fatty degeneration higher than grade 3 on the preoperative MRI. Conclusion: Non-anatomical repair for irreparable large and massive rotator cuff tears by the arthroscopic margin convergence technique showed good functional results. It seems to be one of the effective treatment methods for irreparable large and massive rotator cuff tears.

Preliminary Study for Development of Low Dose Radiation Shielding Material Using Liquid Silicon and Metalic Compound (액상 실리콘과 금속화합물을 융합한 저선량 방사선 차폐 소재 개발을 위한 사전연구)

  • Jang, Seo Goo;Han, Su Chul;Kang, Sung Jin;Lim, sung wook;Lee, Sung Soo
    • Journal of radiological science and technology
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    • v.40 no.3
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    • pp.461-468
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    • 2017
  • This study measured and compared the protective clothing using Pb used for shielding in a diagnostic X-ray energy range, and the shielding rates of X-ray fusion shielding materials using Si and $TiO_2$. For the experiment, a pad type shielding with a thickness of 1 mm was prepared by mixing $Si-TiO_2$, and the X-ray shielding rate was compared with 0.5 mmPb plate of The shielding rate of shielding of 0.5 mmPb plate 95.92%, 85.26 % based on the case of no shielding under each 60 kVp, 100 kVp tube voltage condition. When the shielding of $Si-TiO_2$ pad was applied, the shielding rate equal to or greater than 0.5 mmPb plate was obtained at a thickness of 11 mm or more, and the shielding rate of 100% or more was confirmed at a thickness of 13 mm in 60 kVp condition. When the shielding of $Si-TiO_2$ pad was applied, the shielding rate equal to or greater than 0.5 mmPb plate was obtained at a thickness of 17 mm or more, and a shielding rate of 0.5 mmPb plate was observed at a thickness of 23 mm in 100 kVp condition. Through the results of this study, We could confirm the possibility of manufacturing radiation protective materials that does not contain lead hazard using various metalic compound and liquid Si. This study shows that possibility of liquid Si and other metalic compound can harmonize easily. Beside, It is flexible and strong to physical stress than Pb obtained radiation protective closthes. But additional studies are needed to increase the shielding rate and reduce the weight.

A Study on the Bonding Strength, Reactivity and Thermal Properties of Epoxy Resin Mixed with ESBO (에폭시수지-ESBO 혼용 비율에 따른 목재접착제의 접착력, 반응성 및 열분석에 관한 연구)

  • Choi, Jin Lim;Park, Heon
    • Journal of the Korean Wood Science and Technology
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    • v.35 no.3
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    • pp.36-44
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    • 2007
  • The purpose of this study was to investigate thermal stability, reactivity, and bonding strength of existing epoxy resin mixed with the epoxidized soybean oil (ESBO) in order to use soybean oil economically. In the dry shear test, the marked strengths showed $30.5kgf/cm^2$ at the ratio of ESBO to epoxy resin 9 : 1 and $6.2kgf/cm^2$ at the ratio 8 : 2. The bonding strengths of the others, except mixing ratios 2 : 8 and 1 : 9, exceeded the requirement of Korean plywood standard of $7.0kgf/cm^2$. In the wet shear test, the result was $5.8kgf/cm^2$ at the ratio 9 : 1. There were no thickness swelling and moisture absorption in the water resistance of the film. The value of activation energy, Tg (${\Delta}E$), by DSC analysis showed between $110^{\circ}C$ and $120^{\circ}C$ through all ratios. Epoxy in the epoxy resin fully reacted with the hardener (TETA), but it is difficult to decide that epoxys in the ESBO were reacted directly with the hardener from FT-IR analysis. As the mixing ratio of ESBO increased, the thermal stabilities dropped from TGA analysis. From the comprehensive view on the results of above experiments, it could be confirmed through experiments that the ESBO in the mixed adhesive of epoxy resin/ESBO played a role as an extending agent level of epoxy adhesive, and we were able to know that in order to utilize ESBO as an adhesive, a study should be performed on the condition of hardening, inducible of the hardening reaction.

Adoption and Efficacy of ISO 15189 in Medical Laboratories for Diagnostic and Research (메디컬시험기관에서 ISO 15189 도입의 필요성과 시행의 효용성)

  • Yang, Man-Gil;Lee, Won Ho;Jun, Jin Hyun
    • Korean Journal of Clinical Laboratory Science
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    • v.48 no.2
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    • pp.158-167
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    • 2016
  • The requirements for medical laboratories ISO 15189 is examined in organization and a quality management system, stressing the importance of evidence, document control, and control of records and clinical material. Medical services are provided from the areas of resource management, and pre-examination, examination and post-examination processes. The main goal of ISO 15189 accreditation is to improve the quality of laboratory services provided for patients and clinical users not only through compliance with consensually developed and harmonized requirements but also by adopting the philosophy of continual improvement using the Plan-Do-Check-Act cycle. Laboratory quality should be evaluated and improved in all steps of the testing process as the state-of-the art indicates that the pre- and post-analytical phases are more vulnerable to errors than the intra-analytical phase. The Korea Laboratory Accreditation Scheme (KOLAS), a national accreditation body, provides medical laboratory accreditations for appropriate approaches to evaluating the competence of a medical laboratory in providing effective services to its customers and clinical users. Adoption of ISO 15189 in 2010s as a government policy has been delayed, and only 5 laboratories have been accredited to date in Korea. The medical laboratories should seek the adoption of ISO 15189 with a positive attitude for quality improvement and strengthening of international competitiveness.

Spectroscopic Studies on U(VI) Complex with 2,6-Dihydroxybenzoic acid as a Model Ligand of Humic Acid (분광학을 이용한 흄산의 모델 리간드인 2,6-Dihydroxybenzoic acid와 우라늄(VI)의 착물형성 반응에 관한 연구)

  • Cha, Wan-Sik;Cho, Hye-Ryun;Jung, Euo-Chang
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.9 no.4
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    • pp.207-217
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    • 2011
  • In this study the complex formation reactions between uranium(VI) and 2,6-dihydroxybenzoate (DHB) as a model ligand of humic acid were investigated by using UV-Vis spectrophotometry and time-resolved laser-induced fluorescence spectroscopy (TRLFS). The analysis of the spectrophotometric data, i.e., absorbance changes at the characteristic charge-transfer bands of the U(VI)-DHB complex, indicates that both 1:1 and 1:2 (U(VI):DHB) complexes occur as a result of dual equilibria and their distribution varies in a pH-dependent manner. The stepwise stability constants determined (log $K_1$ and log $K_2$) are $12.4{\pm}0.1$ and $11.4{\pm}0.1$. Further, the TRLFS study shows that DHB plays a role as a fluorescence quencher of U(VI) species. The presence of both a dynamic and static quenching process was identified for all U(VI) species examined, i.e., ${UO_2}^{2+}$, $(UO_2)_2{(OH)_2}^{2+}$, and $(UO_2)_3{(OH)_5}^+$. The fluorescence intensity and lifetimes of each species were measured from the time-resolved spectra at various ligand concentrations, and then analyzed based on Stern-Volmer equations. The static quenching constants (log $K_s$) obtained are $4.2{\pm}0.1$, $4.3{\pm}0.1$, and $4.34{\pm}0.08$ for ${UO_2}^{2+}$, $(UO_2)_2{(OH)_2}^{2+}$, and $(UO_2)_3{(OH)_5}^+$, respectively. The results of Stern-Volmer analysis suggest that both mono- and bi-dentate U(VI)-DHB complexes serve as groundstate complexes inducing static quenching.

Studies on the Strength of Briquette Ash Hardened by Cement (연탄재를 시멘트로서 경화(硬化)시켰을 때의 강도(强度)에 관(關)한 연구(硏究))

  • Kim, Seong-Wan
    • Korean Journal of Agricultural Science
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    • v.6 no.1
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    • pp.45-55
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    • 1979
  • This study made to find the variation of strengths of briquette ash which were hardened into cement. The briquette ash were mixed with the cement, ((cement (90%)+slaked lime (10%)) and ((cement (80%)+fly ash (20%)) in the ratio of 1:2, 1:3, 1:4, 1:5, 1:7 and 1:9, respectively, and these were compared with the one made of cement plus standard sand in the strengths of compression, tension and bending at the ages of 7 days and 28 days. The results from the study conducted preliminary without studying the economical aspects or duration of the products are summarized as follows: 1. The compressive strengths of mortar made of 1 to 2 ratios of cement to briquette ash, (cement+slaked lime) to briquette ash and (cement+fly ash) to briquette ash were 84%, 90% and 75% at the age of 7 days and 84.9%, 73.5% and 69.8%, respectively of those of Korean Standard values. 2. The compressive strength s of mortar made of 1 to 2 ratios of cement to briquette ash, (cement+slaked lime) to briquette ash and (cement+fly ash) to briquette ash were 69.3%, 75.1% and 41.3% at the age of 7 days and 56.4%, 49%, and 46.5% at the age of 28 days, respectively of the mortar made of standard sand. 3. The tension strengths of mortar made of 1 to 2 ratios of cement to briquette ash, (cement+slaked lime) to briquette ash, and (cement+fly ash) to briquette ash were 64.4%, 47.1% and 35.4% at the age of 7days and 69.6%, 64.8%, and 57.3%, respectively of that of the mort ar produced with standard sand. 4. The bending strengths of mortar made of 1 to 2 ratios of cement to briquette ash, (cement+slaked lime) to briquette ash, and (cement+fly ash) to briquette ash were 46.3%, 65.9% and 39.1% at the age of 7 days and 89.9%, 96.7%, and 85.1%, respectively of that of mortar produced with standard sand. 5. The bending strength of the mortar was lower than that of cement mortar, when the briquette ash were harqened into cement. However, the mortar produced by such method seemed to be used as the secondary products of cement or concrete. The additional usefullness of the hardened biquette ash can be found in contributing toward the solving the various pollution problems, the saving the labor costs needed to clean-up waste materials, and the saving the construction materials.

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