• 대한치과교정학회지
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• 제52권6호
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• pp.439-450
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• 2022

This case report describes the treatment of an adult female patient with a history of periodontal disease, Class I malocclusion with extrusion, dental spaces, and pathologic tooth migration. The patient was treated with clear aligners, which effectively controlled the strength and direction of orthodontic forces after 3 months of systematic periodontal treatment. The Peer Assessment Rating (PAR) index was calculated from study models before and after treatment. The pretreatment PAR score was 24, and the posttreatment PAR score was 4. The PAR score for this patient changed by 83%. Satisfactory appearance and good function were achieved for this patient.

• 한국심리학회지 : 문화 및 사회문제
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• 제8권2호
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• pp.33-49
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• 2002

본 연구에서는 성인기 자녀 381명을 대상으로 가족분화수준, 가족관계의 질 및 친밀감간의 관계를 살펴보았다. 첫째, 가족분화수준과 가족관계의 질간의 관계를 통하여 가족분화의 개념이 원가족에 대해 지각하는 정서적 건강과 실제 가족관계에서 심리적 안녕감을 나타내는 개념인지 알아보았다. 그 결과, 가족분화수준과 가족관계의 질간에는 유의한 정적 상관을 보였다. 둘째, 원가족의 가족분화수준과 성인기 자녀의 이성파트너와의 친밀감간의 관계를 토대로 원가족의 부모와의 정서적 역동이 성인기 자녀의 현재 이성파트너와의 관계에 영향을 미치는지 살펴보았다. 연구결과, 성인기 자녀는 모든 하위체계에서 원가족의 가족분화수준과 이성파트너와의 친밀감간의 관계에서 유의한 정적 상관을 보였으며, 아들이 딸보다 부모의 가족분화수준에 민감한 것으로 나타났다.

• 한국발생생물학회지:발생과생식
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• 제14권1호
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• pp.35-41
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• 2010

Mammalian reproduction is regulated by a feedback circuit of the key reproductive hormones such as GnRH, gonadotropin and sex steroids on the hypothalamic-pituitary-gonadal axis. In particular, the onset of female puberty is triggered by gain of a pulsatile pattern and increment of GnRH secretion from hypothalamus. Previous studies including our own clearly demonstrated that genistein (GS), a phytoestrogenic isoflavone, altered the timing of puberty onset in female rats. However, the brain-specific actions of GS in female rats has not been explored yet. The present study was performed to examine the changes in the activities of GnRH neurons and their neural circuits by GS in female rats. Concerning the drug delivery route, intracerebroventricular (ICV) injection technique was employed to eliminate the unwanted actions on the extrabrain tissues which can be occurred if the testing drug is systemically administered. Adult female rats (PND 100, 210-230 g BW) were anaesthetized, treated with single dose of GS ($3.4{\mu}g$/animal), and sacrificed at 3 hrs post-injection. To determine the transcriptional changes of reproductive hormone-related genes in hypothalamus, total RNAs were extracted and applied to the semi-quantitative reverse transcription polymerase chain reaction (RT-PCR). ICV infusion of GS significantly raised the transcriptional activities of enhanced at puberty1 (EAP-1, p<0.05), glutamic acid decarboxylase (GAD67, p<0.01) which are known to modulate GnRH secretion in the hypothalamus. However, GS infusion could not change the mRNA level of nitric oxide synthase 2 (NOS-2). GS administration significantly increased the mRNA levels of KiSS-1 (p<0.001), GPR54 (p<0.001), and GnRH (p<0.01) in the hypothalami, but decreased the mRNA levels of LH-$\beta$ (p<0.01) and FSH-$\beta$ (p<0.05) in the pituitaries. Taken together, the present study indicated that the acute exposure to GS could directly activate the hypothalamic GnRH modulating system, suggesting the GS's disrupting effects such as the early onset of puberty in immature female rats might be derived from premature activation of key reproduction related genes in hypothalamus-pituitary neuroendocrine circuit.

• 대한치과교정학회지
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• 제18권1호
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• pp.127-139
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• 1988

Esthetic is one of the prime goal of the orthodontic treatment. It is represented by the word of harmony or balance. There is no absolute esthetic norm but it is important to study about it in orthodontic and orthognatic surgical treatment planning. The purpose of this study is to obtain the norm of Korean female adolescents who were candidates of 1986, 1987 Miss Korea Beauty Contest. The 77 individual samples were selected and studied by cephalometric analysis. Obtained results were as follows: 1 Korean esthetic norm was obtained. 2. Simple correlation coefficient was obtained between each measurements. 3. Holdaway ratio of Korean beauty was 3.3 : 1. 4. To compare with caucasian, profile of Korean beauty had less prominant nose, more prominant lip and deeper sulcus depth.

• Tuberculosis and Respiratory Diseases
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• 제55권1호
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• pp.107-112
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• 2003

A congenital cystic adenoid malformation of the lung(CCAM) is characterized by an anomalous fetal development of the terminal respiratory structures, resulting in the adenomatoid proliferation of the bronchiolar elements and cystic formation. CCAM has been detected on the fetus, premature babies and stillborn as well as infants and children. An adult presentation of CCAM is extremely rare. When cystic lesions occur with a repeated infection, an evaluation of the cystic lesions requires a differential diagnosis of CCAM, sequestration, a lung abscess, a pneumatocele and a bronchogenic cyst. The definite treatment of CCAM is the surgical removal of the involved lobe. We report a case of a CCAM in a 24-year-old female with a brief review of the relevant literature.

• 한국임상수의학회지
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• 제18권3호
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• pp.297-303
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• 2001

A female pug was presented with severe anemia, dyspnea and hemoglobinuria. By B- and M-mode echocardiography, the large number of heartworm were founded in the right ventricle, right atrium and pulmonary artery. The heartworm mass was moved from the right ventricle to the right atrium with the motion of the tricuspid value. Paradoxic septum motion were visible in M-mode of left ventrcular outflow tract and chordae tendineae level short-axis view. Flattened interventricular septum was find in B-mode of papillary muscle level short-axis view. In autopsy, 81 adult heartworms and 7 filarial debris were found. Most of adult heartworm were found in the right ventricle and pulmonary artery. 3 of them were found in the venaca and right atrium, respectively.

• BMB Reports
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• 제44권6호
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• pp.393-398
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• 2011

Polydnaviruses are a group of double-stranded DNA viruses and are symbiotically associated with some ichneumonoid wasps. As proviruses, the replication of polydnaviruses occurs in the female reproductive organ at the pupal stage. This study analyzed the effects of two developmental hormones, juvenile hormone (JH) and ecdysteroid, on the viral replication of Cotesia plutellae bracovirus (CpBV). All 23 CpBV segments identified contained a conserved excision/rejoining site ('AGCTTT') from their proviral segments. Using quantitative real-time PCR based on this excision/rejoining site marker, initiation of CpBV replication was determined to have occurred on day 4 on the pupal stage. Pyriproxyfen, a JH agonist, significantly inhibited adult emergence of C. plutellae, whereas RH5992, an ecdysteroid agonist, had no inhibitory effect. Although RH5992 had no effect dose on adult development, it significantly accelerated viral replication. The results of immunoblotting assays against viral coat proteins support the effects of the hormone agonists on viral replication.

• 가정과삶의질연구
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• 제20권1호
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• pp.65-73
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• 2002

The purpose of this study was to describe 1) the prevalence of caregiving among adult men and women in Korea and 2) the characteristics of caregiving context. The main results were as follows: 1) About 1 in 6 adults reported that they provided care for the relatives and friends during the previous year. 2) The proportion of male to female caregivers was similar, indicating a higher prevalence of male involvement than previous studies indicated. Yet, the relationships to care recipients and types of care were found to be different by gender of caregiver 3) Adult caregivers are most likely to provide care for the elderly, but continue to provide care for younger persons as well. 4) A nontrivial proportion of the respondents reported providing care for more than one person, suggesting the need to pay special attention to these multiple caregivers.

• Annals of Clinical Neurophysiology
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• 제24권2호
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• pp.107-110
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• 2022

We describe the case of a 22-year-old female complaining of ophthalmoplegia, which deteriorated with seizure. Leigh syndrome (LS) was diagnosed by identifying the m.9176T>C mutation. She improved with vitamin cocktail therapy plus intravenous methylprednisolone, and had an excellent prognosis. This was the first case of an adult patient with LS presenting with the m.9176T>C mutation and reporting cortical symptoms, which in this case comprised cortical vision loss, and cortical, basal ganglia, and brainstem signal changes on magnetic resonance imaging.

• Journal of Chest Surgery
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• 제28권8호
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• pp.747-753
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• 1995

Patients over 14 years of age who have undergone a surgical correction of a congenital cardiac malformations during period of August 1959 through December 1993 have been reviewed. During this period, there were 6894 cases of congenital cardiac lesions consisting of 4576 acyanotic and 2318 cyanotic cases. Among them, a total of 1389 adults [20.1%with various congenital cardiac malformations, 1126 acyanotic group and 263 cyanotic group were operated on. 677 patients were male and 712 patients were female. There were 444 patients under 20 years of age, 365 patients between 20-24 years, 220 patients between 25-29 years, 138 patients between 30-34 years and 222 patients over 34 years. The most common defects were atrial septal defect which accounted for 500 cases [36.0%and another common malformations were ventricular septal defect [276 cases, 19.9% , patent ductus arteriosus [207 cases, 14.9% , tetralogy of Fallot [185 cases, 13.3%and pulmonary stenosis [44 cases, 3.2%in order of incidence. Overall operative mortality for this series was 2.7% [1.5% of acyanotic group and 7.9% of cyanotic groupcompared with 4.6% of operative mortality of total cases of congenital cardiac malformations [2.9% of acyanotic group and 16.7% of cyanotic group . This reviewed series reveals the incidence of operable congenital heart defects appearing in any adult life and demonstrates that surgical repair can be accomplished with a satisfactory low mortality rate.