• 대한골관절종양학회지
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• 제13권2호
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• pp.190-194
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• 2007

거대 세포종은 서서히 자라는 일측성의 국소형 종물로서 수부에서 흔하고 고관절, 족지관절에서도 보고되나 슬관절내에서는 드물게 발생한다. 이에 저자들은 슬관절 관절강내에서 발생한 거대 세포종 1예를 관절경하에 제거한뒤 병리학적으로 확진하였으며 이를 문헌고찰과 함께 보고하고자 한다.

• 대한골관절종양학회지
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• 제1권1호
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• pp.1-6
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• 1995

Giant cell tumors are primary bone tumors originating from non-osteoblastic connective tissue. The sites of involvement were commonly distal femur, proximal tibia, proximal humerus, distal radius and others (including os calcis, ilium and sacrum). Giant cell tumor located around knee joint has been difficult to treat because of local recurrence following curettage with or without bone graft. Although primary resections reduce recurrence of the lesion, the joint function will be markedly impaired. Marginal excision was very often complicated by a loss of joint integrity since all the giant cell tumors occupy juxtaarticular positions. Techniques involving physical adjuncts(high speed burr and electric cauterization) have been used in the hope of decreasing the rate of local recurrence and avoiding the morbidity of primary resection. A meticulous clinical, radiological and histological evaluation is needed to choose the correct treatment, keeping in mind the possibility of recurrence after each treatment modality.

• 대한골관절종양학회지
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• 제5권1호
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• pp.9-16
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• 1999

A new method of limb sparing by resection, extracorporeal irradiation and reimplantation has several theoretical advantages. This method preserves the mobility of a joint and avoids the problem of loosening or breakage of tumor prosthesis. This study involved using extracorporeal irradiated autogenous joint transplantation for reconstruction after en bloc resection, and observed the periods of functional union and histological changes in irradiated tissue of the knee joint. This study also aimed to clarify whether the degeneration of articular cartilage is induced in rabbits by a single 50Gy dose of irradiation at the knee joint. Twenty New Zealand rabbits about three kilograms were randomized into two groups of 10 rabbits each. In group 1, as control, we resected the knee joint followed by reimplantation without irradiation. Group 2 received extracorporeal irradiation on the resected knee joint followed by reimplantation. Following are the results of these observations. The osteotomy site showed external callus formation in the roentgenographic finding eight weeks after reimplantation. There was marked degenerative changes in the collagen fiber of the irradiated anterior cruciate ligament and meniscus during the fourth week, but new blood-vessel formation was observed in the vicinity. There was degenerative changes in the collagen fiber of articular cartilage treated extracorporeal irradiation at four and eight weeks in the scanning electron micrographic findings. These findings was in contrast to those of subchondral bone which showed decreased cellularity and empty lacuna at four and eight weeks. Autoradiography demonstrated active [$^3H$]uridine incorporation by irradiated chondrocyte at eight weeks after reimplantation. These results indicate that when destruction of the articular cartilage and soft tissue of the knee joint is not severe, extracorporeal irradiation and reimplantation can be used with several advantage in maintaining movement of the joint while avoiding problems of tumor prosthesis and rejection, and therefore extracorporeal irradiated autogenous joint transplantation can be used as a limb-sparing procedure for temporary biological spacer in the childhood bone tumor around the knee.

• 대한정형외과 초음파학회지
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• 제1권1호
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• pp.18-22
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• 2008

결절종(ganglion cyst)은 관절 또는 건막과 연결된 두꺼운 결체 조직내에 맑고 높은 점도의 액체를 함유한 낭포성 종양으로 슬관절 주위에서는 흔하지 않다. 73세 여성의 슬관절 내측에 발생한 딱딱한 종괴가 만져졌으며 종양의 가능성을 의심할 만 하였다. 이것을 초음파로 간단하게 결절종임을 밝혀내고 실시간으로 병변내 주사 바늘의 위치를 확인하면서 흡인하여 확진할 수 있었다. 초음파는 낭종의 진단에는 매우 편리하고 유용한 진단 기구임을 알 수 있었다.

• 대한골관절종양학회지
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• 제18권2호
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• pp.51-58
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• 2012

목적: 슬관절 주위에 발생한 골종양 환자에서 종양 대치물을 이용한 재건술의 결과와 보행 분석의 유용성을 알아보고자 하였다. 대상 및 방법: 2001년부터 2010년까지 슬관절 주위에 발생한 골종양에 대하여 광범위 절제술 후 종양 대치물을 이용한 재건술을 시행 받은 30명 중 7명을 대상으로 하였으며 기능적 결과 및 보행 분석 검사를 평가하였다. 결과: SF-36 점수는 신체적, 정신적 역할제한 항목에서 각각 100% (100점)으로 높은 점수를 보였으며 일반 건강상태, 신체적 기능 정도, 활력, 사회적 기능에서 낮은 점수를 나타냈다. 또한 MSTS 평가의 종합 평균 점수는 88.1% (23.8점[17-27])였다. 보행 분석 검사상 평균 보행속도 97.2 m/s, 평균 분속수 105.6 step/min, 평균 활보장 111.3 m, 평균 보장 61.5 cm, 유각기 39.8%cycle, 입각기 60.1%cycle, 평균 단하지 지지기 37.1%cycle, 평균 양하지 지지기 13.0%cycle, 평균 발 들림시기 60.7%cycle였다. 결론: 슬관절 주위 종양에 대한 광범위 절제술 후 종양 대치물을 이용한 재건술은 좋은 기능적결과를 기대할 수 있으며, 보행 분석 검사는 술후 환자의 상태를 정량적으로 평가함으로써 보행 모습 및 기능을 객관화 할 수 있는 한 방법으로 사료되며 기능적 평가 방법과 함께 치료 및 술 후 재활 계획을 세우는데 도움이 되리라 생각된다.

• 대한골관절종양학회지
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• 제3권1호
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• pp.18-25
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• 1997

Prosthetic replacement is one of the most common methods of reconstruction after resection of malignant tumor around the knee. Gait analysis provides a relative objective data about the gait function of patients with prosthesis. The purpose of this study was to compare the gait pattern of the patients who underwent limb salvage surgery with prosthesis for distal femur and that of patients with prosthesis for proximal tibia. This study included ten patients (4 males, 6 females, mean age 22.7 years, range 14-36) who underwent a wide resection and Kotz hinged modular reconstruction prosthesis replacement and six normal adult(Control). The site of bone tumor was the distal femur (Group 1) in six patients and proximal tibia (Group 2) in 4 patients. The follow-up period ranged from 15 to 82 months (mean : 33 months). The evaluation consisted of clinical assessment, radiographic assessment, gait analysis using VICON 370 Motion Analysis System. The gait analysis included the linear parameters such as, walking velocity, cadence, step length, stride length, stance time, swing time, single support and double support time and the three-dimensional kinematics (joint rotation angle, velocity of joint rotation) of ankle, knee, hip and pelvis in sagittal, coronal and transverse plane. For the kinetic evaluation, the moment of force (unit: Nm/kg) and power (unit: Watt/kg) of ankle, knee and hip joint in sagittal, coronal and transverse plane. In the linear parameters, cadence, velocity, step time and single support were decreased in both group 1 and group 2 compared with control. Double support decreased in group 2 compared with control significantly(p<.05). In contrast to our hypothesis, there was no significant difference between group 1 and group 2. In Kinematics, we observed significant difference (p<.05) of decreased knee flexion in loading response (G2

• 대한골관절종양학회지
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• 제13권1호
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• pp.31-36
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• 2007

목적: 악성 골종양 환자에서 사지구제술 후 결손부위의 재건방법 중 체외 방사선 조사를 이용한 재활용 자가골 이식술이 한 방법으로 시행되고 있다. 그러나 관절주위에서 발생한 종양의 수술시 관절 내 절제술 및 재활용 자가 관절이식술 시행 후 발생하는 관절의 불안정성, 진행되는 관절염 등의 단점이 있다. 이러한 단점을 보완하기 위해 생각되어진 관절외 절제술 및 체외 방사선 조사를 이용한 재활용 전 자가 관절 이식술을 시행하여 그 결과를 알아보고자 하였다. 대상 및 방법: 1997년 6월부터 2006년 2월까지 슬관절 주위의 악성 골종양으로 진단받고, 동일한 수술을 시행한 5례를 대상으로 하였다. 추시 중 합병증과 재발의 유무를 확인하기 위해 주기적 진찰 및 검사를 시행하였다. 추시 기간은 최단 93개월에서 최고 105개월로 평균 100개월이었으며, 평균 나이는 21.6세였다. 결과: 단순 방사선상 골 유합기간은 평균 15.6개월(9~40개월)이었으며, Enneking 기준의 기능적 평가결과 평균 71.6%(66.6~80%)였으며 재발은 1례도 없었다. 합병증은 골단부 붕괴 3례, 관절 불안정성 5례가 발생하였고, 전례에서 종양 대치물로 관절 치환술을 시행하였다. 결론: 슬관절 주위에 원발성 골종양이 발생한 경우 체외 방사선 조사를 이용한 재활용 전자가 관절이식술은 관절 불안정성을 일으켜 영구적인 관절 기능을 유지하지 못하므로 종양 대치물의 사용이 적절할 것으로 생각된다.

• 대한골관절종양학회지
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• 제1권2호
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• pp.145-153
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• 1995

Giant cell tumor is most frequently found in juxtaarticular region, and difficult to treat because of local recurrence. Although primary resections reduce recurrence, the joint function will be markedly impaired. Techniques involving physical adjuncts(high speed burr and electric cauterization), acrylic cement or en bloc resection with VFG(vascularized fibular graft) have been employed to reduce local recurrence. From October 1984 to April 1994, twenty-nine patients diagnosed as giant cell tumor were treated at department of Orthopaedic Surgery, School of Medicine, Kyung Hee University. There were eleven men and 18 women, ranging in age from 17 to 52 years(mean: 34 years). The average follow-up period was four years and five months. The location of the lesion was around the knee in 15, distal radius in three, femoral head in three, and others in eight patients. Fifteen patients around the knee joint were treated with several modalities; curettage with bone graft in five, curettage with cement filling in three, curettage with bone graft and physical adjuncts in five, en bloc resection with VFG in one and en bloc resection with arthroplasty in one patient. The functional results, according to the Marshall's knee score, were excellent in one, good in two, and fair in two after the curettage with bone graft, good in three after the curettage with bone cement filling, excellent in one, good in four after the curettage with bone graft and physical adjuncts, and good in two after the en bloc resection with VFG or arthroplasty. Three patients had local recurrence among 15 patients with giant cell tumor around knee. Vascularized fibular graft around wrist joint provided good functional restoration without local recurrence in all three patients who had giant cell tumor in distal radius. Although there is no statistical significance, it seems that curettage with bone graft using physical adjuncts or acrylic cement reveals better results than simple curettage with bone graft. Excellent functional result were obtained without local recurrence by using vascularized fibular graft after en bloc resection.

• 대한골관절종양학회지
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• 제20권2호
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• pp.85-88
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• 2014

국소형 거대 세포종은 주로 지 관절의 활액막에서 호발하는 것으로 알려져 있으며 슬관절 내에서는 드물게 발생하는 것으로 알려져 있다. 병리학적으로 다핵의 거대 세포를 특징적으로 가지는 질환으로 완전 절제 시 재발율은 낮다. 슬관절 내에 발생하는 경우 무증상에서 간헐적 잠김 증상까지 다양하게 나타날 수 있으며, 관절경적으로 완전 절제가 가능하나 불완전 절제 시 45%까지 재발하는 것으로 보고되고 있다. 저자들은 후방 십자 인대의 전연에 발생한 거대 세포종 1예를 관절경 하에서 절제 후 병리학적으로 확진하여 이를 보고하고자 한다.

• Archives of Reconstructive Microsurgery
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• 제21권2호
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• pp.143-148
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• 2012

Purpose: This report presents the authors' experience of twelve patients with sural artery flap for soft tissue defects around the knee joint. Materials and Methods: The patients' age ranged from 25 to 80 years; seven of the patients were male and five were female. The cause of soft-tissue defects involved wide excision for malignant soft tissue tumor, tumor prosthesis related infection, infection after total knee arthroplasty and chronic osteomyelitis. Postoperative range of motion was checked. The sensibility of flap was evaluated by Semmes-Weinstein monofilaments and two-point discrimination. Results: All flaps survived and provided satisfactory coverage of the defect. There was no complication except one delayed skin graft incorporation at donor site. Seven knee joints which had been stiff previously gained average 58 degrees of ROM postoperatively. All flaps retained sensibility and showed no significant increase in sensory thresholds comparing with contralateral side. Conclusion: Sural artery flap not only shows high survival rate and broad coverage ability, but also offers improvement in range of motion and preservation of sensation. We speculate that sural artery flap is valuable for the reconstruction of the soft tissue defects around knee joint.