• Bulletin of the Korean Chemical Society
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• v.34 no.12
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• pp.3629-3634
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• 2013

In this study, an improved method for the quantitative analysis of ginkgolic acids (GAs) in Ginkgo biloba leaf extract was developed. The samples were extracted with a mixture of chloroform and 50 % ethanol, after which the chloroform extract was dried and reconstituted in methanol. GAs with 13:0, 15:1, and 17:1 in the extract were successfully separated within 40 min and determined with high throughput performance using an online column-switching HPLC method using an SP column C8 SG80 ($4.6{\times}150mm$, $5{\mu}m$) and a Cadenza 5CD C18 column ($4.6{\times}150mm$, $3{\mu}m$). The developed HPLC method was validated for Ginkgo biloba leaf extract. The validation parameters were specificity, linearity, precision, accuracy, and limits of detection and quantitation (LODs and LOQs, respectively). It was found that all of the calibration curves showed good linearity ($r^2$ > 0.9993) within the tested ranges. The LODs and LOQs were all lower than $0.04{\mu}g/mL$. The established method was found to be simple, rapid, and high throughput for the quantitative analysis of GAs in ten commercial Ginkgo biloba leaf extract and dietary supplements. The samples were also analyzed in LC-electrospray ionization (ESI) tandem mass spectrometry (MS/MS) - multiple-ion reaction monitoring (MRM) mode to confirm the identification results that were obtained by the column switching HPLC-DAD method. The developed method is considered to be suitable for the routine quality control and safety assurance of Ginkgo biloba leaf extract.

• Journal of The Korean Society of Integrative Medicine
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• v.8 no.3
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• pp.63-69
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• 2020

Purpose : Various research studies are needed to raise the perception of the CE of Korean physical therapists. However, there are little studies have been conducted, and relatively few studies are available to read on online. The purpose of the study is to find out the differences in the perception of CE according to the physical therapist's academic background. In this way, this article intends to strengthen the perception of the CE of health-care workers, such as physical therapists and occupational therapists in the Republic of Korea so that contributing to the development of national health. Methods : Present study showed that 431 out of 563 people who participated in the two meetings of CE conducted by the Gwangju Metropolitan City of the Korea Physical Therapy Association responded in the survey in 2015. Among them, only 238 people were surveyed on the awareness of CE in 2014, excluding 181 questionnaires due to poor responses and 112 questionnaires that did not participate in CE in the previous year. Descriptive analyses were conducted to identify the perception among those who experienced CE, and simple linear regression analysis was performed using dummy variables to identify awareness of the education based on their academic background. Results : Question 3 (p=.000, R2=.067) was significant in the significance test of the regression equation for perception of the CE (p<.05). Question 1 (p=.687), 2 (p=.066), 4 (p=.430), 5 (p=.085), and 6 (p=.054), 7 (p=.111), 8 (p=.088), 9 (p=.213), 10 (p=.191) and 11 (p=. 169), the regression formula was not significant (p>.05). Conclusion : Physical therapists had a moderate perception of the need for a CE and had the idea that improvements were required in what was provided in that education. In addition, there was no statistically significant difference, although there was a greater awareness of CE in the Master of Science Course or higher than college or university graduates.

• The Korean Journal of Food And Nutrition
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• v.35 no.5
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• pp.389-397
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• 2022

A total of 51 vegetables and fruits, commonly consumed agriculture products in Korea, were analyzed for their α-carotene, β-carotene, and β-cryptoxanthin contents as provitamin A. The beta-carotene content (㎍/100 g) was high in a few green leaf vegetables such as coriander (5,924.07), gegeol radish leaf (5.855.72), and curried mallow (5,138.01), while α-carotene and β-cryptoxanthin contents were not detected. The β-carotene in 8 kinds of 20 general vegetables was detected in the range of 214.06~1,437.67 ㎍/100 g, while α-carotene was detected at 460.17 ㎍/100 g in only old pumpkin. The β-cryptoxanthin was detected in the range of 106.55~315.49 ㎍/100 g in Japanese elm, watermelon, white cucumber, and lettuce. However, carotenoids were not detected in 10 kinds of agricultural products including oriental melon, potato, etc. In fruits, the beta-carotene contents ranged from 165.72~3,997.39 ㎍/100 g, showing maximum value in apple mango and minimum value in persimmon. The β-cryptoxanthin was detected at 232.22 ㎍/100 g in only passion fruit, while the α-carotene was detected at 77.25 ㎍/100 g in only darae. Thus, based on the analyzed results of carotenoids of agriculture products consumed or cultivated in Korea, and it was found that green leaf vegetables comprise high beta-carotene overall.

• Annual Conference on Human and Language Technology
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• 2020.10a
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• pp.47-53
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• 2020

문서 요약은 주어진 문서에서 핵심 내용만을 남긴 간결한 요약문을 생성하는 일로 자연어처리의 주요 분야 중 하나이다. 최근 방대한 데이터로부터 심층 신경망 표상을 학습하는 기술의 발전으로 문서 요약 기술이 급진적으로 진화했다. 이러한 데이터 기반 접근 방식에는 모델의 학습을 위한 양질의 데이터가 필요하다. 그러나 한국어와 같이 잘 알려지지 않은 언어에 대해서는 데이터의 획득이 쉽지 않고, 이를 구축하는 것은 많은 시간과 비용을 필요로 한다. 본 논문에서는 한국어 문서 요약을 위한 대용량 데이터셋을 소개한다. 데이터셋은 206,822개의 기사-요약 쌍으로 구성되며, 요약은 표제 형식의 여러 문장으로 되어 있다. 우리는 구축한 학습 데이터의 적합성을 검증하기 위해 수동 평가 및 여러 주요 속성에 대해 분석하고, 기존 여러 문서 요약 시스템에 학습 및 평가하여 향후 문서 요약 벤치마크 데이터셋으로써 기준선을 제시한다. 데이터셋은 https://github.com/hong8e/KHS.git의 스크립트를 통해 내려받을 수 있다.

• Journal of Trauma and Injury
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• v.37 no.2
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• pp.97-105
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• 2024

Purpose: Massive transfusion protocols (MTPs) implementation improves clinical outcomes of the patient's resuscitation with hemorrhagic trauma. Various predictive scoring system have been used and studied worldwide to improve clinical decision. However, such research has not yet been studied in Korea. This systematic review aimed to assess the predictors of MTPs activation in patients with trauma in Korea. Methods: The PubMed, Embase, Cochrane Library, Research Information Sharing Service databases, KoreaMed, and KMbase were searched from November 2022. All studies conducted in Korea that utilized predictors of MTPs activation in adult patients with trauma were included. Results: Ten articles were eligible for analysis, and the predictors were assessed. Clinical assessments such as systolic and diastolic blood pressure, shock index (SI), prehospital modified SI, modified early warning system (MEWS) and reverse SI multiplied by the Glasgow Coma Scale (rSIG) were used. Laboratory values such as lactate level, fibrinogen degradation product/fibrinogen ratio, and rotational thromboelastometry (ROTEM) were used. Imaging examinations such as pelvic bleeding score were used as predictors of MTPs activation. Conclusions: Our systematic review identified predictors of MTPs activation in patients with trauma in Korea; predictions were performed using tools that requires clinical assessments, laboratory values or imaging examinations only. Among them, ROTEM, rSIG, MEWS, SI, and lactate level showed good effects for predictions of MTPs activation. The application of predictors for MTP's activation should be individualized based on hospital resource and skill set, also should be performed as a clinical decision supporting tools.

• 보존과학연구
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• s.37
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• pp.27-41
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• 2016

This study surveyed color awareness and color systems according to pedigree(Ilseob, Woljoo, Hyegak, Manbong ect.) targeting Dancheongjang (craftsman) who has inherited Dancheong (traditional multicolor). From the survey of color awareness, standardized color system of 'traditional color' awareness by Dancheongjang is 'the color inherited by the master' and it was identified that there is the standardized color system in awareness and its standard is either same or similar to traditional Dancheong. Also, according to each period, colors of Dancheong have been changed, it was thought that change in color materials and preference had went with times. From eleven main colors of Dancheong, chromaticity materials which were preferred by Dancheongjang were analyzed by the faction of Dancheongjang and colors and it resulted in a variety of color ranges over all. In the case of Yangnok, Noerok, Juhong it showed a high deviation with a wide color range while there was a low deviation with a narrow color range in Hayeop, Daja, Seokganju. Through this study it was difficult to identify clear correlations and tendencies of color system by the faction of Dancheongjangs. This is judged to be a reflection of the subjective artistry of the members.

• Journal of Korea Game Society
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• v.15 no.4
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• pp.29-38
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• 2015

In the stealth game design, level designers are to develop many interesting game environments with a variety of difficulties. J. Tremblay and his co-authors developed a Unity-based level design tool to help and automate this process. Given a map, if the designer inputs several game factors such as guard paths and velocities, their vision, and the player's initial and goal positions, then the tool visualizes simulation results including (clustered) possible paths a player could take to avoid detection. Thus with the help of this tool, the designer can ensure in realtime if the current game factors result in the intended difficulties and players paths, and if necessary adjust the factors. In this note, we present our improvement on this tool in two aspects. First, we integrate a function that if the designer inputs some vertices in the map, then the tool systematically generates and suggests interesting guard paths containing these vertices of various difficulties, which enhances its convenience and usefulness as a tool. Second, we replace the collision-detection function and the RRT-based (player) path generation function, by our new collision-check function and a Delaunay roadmap-based path generation function, which remarkably improves the simulation process in time-efficiency.

• Journal of Korean Society on Water Environment
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• v.27 no.4
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• pp.467-474
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• 2011

In an effort to investigate water pollution characteristics of Juam lake, water samples were collected from three sites (Sites A, B, and C) of Oenam stream which is a typical tributary of rural watershed in the lake and analyzed for N concentration and the corresponding isotope ratio (${\delta}^{15}N$) of ${NO_3}^-$. Concentrations of ${NO_3}^-$ were not dramatically different among the sites; $0.8{\pm}0.2mgNL^{-1}$ (range: $0.0{\sim}4.3mgNL^{-1}$) for Site A, $1.1{\pm}0.2mgNL^{-1}$ ($0.0{\sim}4.3mgNL^{-1}$) for Site B, and $1.1{\pm}0.1mgNL^{-1}$ ($0.1{\sim}2.6mgNL^{-1}$) for Site C. Meanwhile, ${\delta}^{15}N$ tended to decrease with river flow; it was highest for Site A ($45.5{\pm}5.3$‰) followed by Site B ($19.7{\pm}2.0$‰) and Site C ($8.7{\pm}1.5$‰). Such high ${\delta}^{15}N$ values of ${NO_3}^-$ in Site A suggested that ${NO_3}^-$ derived from livestock feedlot (specifically livestock excrete of which ${\delta}^{15}N$ is higher than 10‰) is the predominant pollution sources despite mountainous area occupied the most of land-use in the watershed. Using the two-sources isotope mixing model, it was estimated that the contribution of cropping activities (i.e. fertilization) became greater in down-stream area (Sites B and C) due to the higher agricultural land-use than the up-stream area (Site A). Particularly, during the active cropping season, the low contribution of organic pollution sources indicated that domestic sewage was not the predominant pollution source. Therefore, it was suggested that agricultural sources such as livestock farming and cropping rather than mountainous and residential are the dominant sources of water pollution in the study area. These results could be effectively utilized in elucidating water pollution sources in rural areas and selecting water management practices.

• Journal of Conservation Science
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• v.37 no.6
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• pp.679-688
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• 2021

In this study, we investigated the applicability of a termiticide based on metofluthrin for termite control on traditional wooden buildings. To evaluate their mortality, termites were exposed to the agent, diluted to various concentrations, for seven days; it was found that it had a sufficient insecticidal effect although there was a difference depending on the degree of agent dilution. Next, the effect on Dancheong, used in traditional wooden structures, was measured based on the color change according to the number of agent treatments. The results showed that only the color difference value of two pigments (i.e., Bun and Juhong) was measured as 3.0 or higher. However, there this varied according to the dilution ratio. Thus, it was found that most pigments had little effect on the color of Dancheong. Finally, the termiticidal efficacy of the agent when applied to wood was evaluated. We found that the specimens coated with 10-fold and 20-fold dilutions exhibited 2.83 and 6.28% mass loss, respectively. The 10-fold dilution satisfied the performance of termiticide as a mass loss of less than 3%. In conclusion, the metofluthrin-based agent used in this study has little effect on various Dancheong pigments and has a termiticidal effect against termites; it is therefore suggested that it may be used in preserving traditional wooden cultural properties in Korea.