• Biomolecules & Therapeutics
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• v.27 no.6
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• pp.562-569
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• 2019

Niacinamide (NIA) is a water-soluble vitamin that is widely used in the treatment of skin diseases. Moreover, NIA displays antioxidant effects and helps repair damaged DNA. Recent studies showed that particulate matter 2.5 ($PM_{2.5}$) induced reactive oxygen species (ROS), causing disruption of DNA, lipids, and protein, mitochondrial depolarization, and apoptosis of skin keratinocytes. Here, we investigated the protective effects of NIA on $PM_{2.5}$-induced oxidative stress in human HaCaT keratinocytes. We found that NIA could inhibit the ROS generation induced by $PM_{2.5}$, as well block the $PM_{2.5}$-induced oxidation of molecules, such as lipids, proteins, and DNA. Furthermore, NIA alleviated $PM_{2.5}$-induced accumulation of cellular $Ca^{2+}$, which caused cell membrane depolarization and apoptosis, and reduced the number of apoptotic cells. Collectively, the findings show that NIA can protect keratinocytes from $PM_{2.5}$-induced oxidative stress and cell damage.

• Journal of Convergence for Information Technology
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• v.11 no.6
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• pp.107-112
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• 2021

This study aims to analyze a cafe built by reflecting the characteristics of Jeju among the cafes in Jeju. This is to provide practical help to prospective prep entrepreneurs who want to start a cafe in Jeju. The cafe reflecting the characteristics of Jeju maintains its own competitiveness and constant interest of tourists by securing differentiation and uniqueness. In addition, by looking at the characteristics of Jeju applied to cafe architecture, the academic foundation for understanding the Jeju and applicable characteristics of Jeju were summarized. The study was conducted in parallel with literature analysis and on-site analysis, and as a result, the following contents were found. First, it is a reflection of Jeju's phenomenal materiality. Second, it is a reflection of Jeju's interpretive everyday life. Third, it is a reflection of Jeju's materiality time. In this regard, if prep entrepreneurs start a cafe that reflects the characteristics of Jeju, they can create a cafe with very specific characteristics if they integrate the three characteristics above.

• Journal of the Korean Society of Radiology
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• v.82 no.2
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• pp.481-486
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• 2021

Endosalpingiosis is a condition that causes the non-neoplastic proliferation of ectopic tubal epithelium. Florid cystic endosalpingiosis is an atypical subtype that is very rarely reported. It presents as a mass-like feature and therefore needs to be differentiated from tumorous conditions. Here, we report the imaging findings of a case of multicentric florid cystic endosalpingiosis in the extraperitoneal pelvic cavity and the retroperitoneal spaces.

• Journal of the Korean Society of Radiology
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• v.85 no.2
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• pp.463-467
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• 2024

Acupuncture is increasingly being used in Asian countries and is generally considered a relatively safe procedure. However, adverse events have been reported consistently. Therefore, clinicians should be aware of the possibility of acupuncture-related complications and should actively treat serious cases. We report a case of an acupuncture-induced large abscess in the retroperitoneal cavity and thigh muscles treated with percutaneous catheter drainage, surgical incision, and drainage.

• Proceedings of the Korea Contents Association Conference
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• 2014.06a
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• pp.411-412
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• 2014

• Proceedings of the Korea Contents Association Conference
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• 2014.06a
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• pp.353-354
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• 2014

• Proceedings of the Korean Environmental Sciences Society Conference
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• 2018.10a
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• pp.214-214
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• 2018

• Tuberculosis and Respiratory Diseases
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• v.84 no.3
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• pp.245-246
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• 2021

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2018.05a
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• pp.375-376
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• 2018

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.21 no.2
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• pp.127-133
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• 2018

Purpose: For 3 consecutive years from 2012-2014, we analyzed the causative factors for why the Jeju Island had the highest obesity prevalences of school children among the 15 provinces in Korea. Methods: From our analysis of 28,026 elementary school children with obesity or normal weight in the 15 provinces, we analyzed 12 factors related to eating habits, exercise habits, lifestyle, and mental health. The differences between the obese and normal weight children were researched. Finally, Jeju was compared with Seoul, which has the lowest obesity prevalence in school age children. Statistical analysis was performed using the chi square test of PASW Statistics ver. 18.0. Results: Compared to the normal weight group, the obese group had significantly higher rates of consuming soft drinks (p<0.001), fast food intake (p=0.019), skipping breakfast (p<0.001), insufficient sleep (p<0.001), bullying experiences (p=0.001) and runaway impulses (p=0.012). Compared to Seoul, Jeju Island had significantly higher rates of Ramen intake (3.4% vs. 5.4%, p=0.021) and meat intake (46.0% vs. 52.9%, p=0.003). On the other hand, Jeju Island was significantly lower than was Seoul in their fruit intake (83.4% vs. 67.1%, p<0.001), vegetable intake (71.4% vs. 64.2%, p=0.001), and intense physical activity (63.4% vs. 47.7%, p<0.001). Meanwhile, insufficient sleep (15.4% vs. 9.6%, p<0.001) and runaway impulses (5.6% vs. 3.3%, p=0.027) in children were significantly lower in Jeju Island than in Seoul. Conclusion: The results of the obesity factor analysis of elementary school students in Jeju Island can be used as useful educational material for lowering the obesity prevalence in Jeju community.