• Journal of Periodontal and Implant Science
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• v.35 no.4
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• pp.1003-1017
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• 2005

이 논문은 단일조사 저출력 $CO_2$ Laser조사가 치주인대 섬유아세포의 증식과 분화에 미치는 영향을 살펴보고 가장 효과적인 에너지와 파워밀도(power density)를 알아보기 위해 다음과 같이 실험하였다. 0.5W 출력, 10.6 ${\mu}m$ 파장, 50 Hz 연속형 $CO_2$ Laser를 사용하여, 실험군은 laser tip과 배양된 세포 사이의 거리를 2cm, 3cm으로 나누고, 조사시간을 1초, 3초로 나누어 4개의 군으로 설정하였고 대조군은 laser를 조사하지 않은 군으로 하였다. 치주인대 섬유아세포의 증삭정도와 골모세포로의 분화정도를 보기 위하여 각각 MTT 실험과 ALP activity 실험을 시행하여 다음과 같은 결과를 얻었다. 1. Laser를 조사하고 난 후 5일째에, 모든 군에서 유의하게 세포가 증식되는 것을 확인할 수 있었고 조사방법간에 유의한 차이가 없었다. 2. 대조군과 살험군에서 0일째에 비하여 3일째, 5일째, 7일째, 10일째에 통계적으로 유의 하게 ALP activity가 증가하였고, 이중 2cm,1sec 군을 제외하면 3일째에서 가장 높은 ALP activity 값을 보였다. 특징적으로 2cm,1sec 군은 3일째부터 10일까지 통계적으로 유의하지는 않지만 시간이 지남에 따라서 ALP activity가 증가함을 보였다. 7일과 10일째에는 2cm,1sec, 3cm,3sec군에서 다른 군에 비하여 큰 activity값을 보였다. 이번실험에서 저출력 $CO_2$ Laser 조사는 세포의 증식보다는 분화에 더 큰 영향을 끼쳤고, 2cm, 1sec, 3cm, 3sec 군이 치주인대 섬유아세포의 분화에 가장 효과적인 laser 조사방법으로 분석되었다.

• Journal of Periodontal and Implant Science
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• v.35 no.2
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• pp.437-448
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• 2005

This study is an analysis of distribution of patients who installed Xive implant in Yonsei University Hospital and types of implant site for about 2 years recall check and cumulative survival rate. 41 implant were used in this study. It shows the conclusion below. 1. Patients at the age of 40s and 50s were 60% of all implant cases and average number of implant was 2.4(man), and 1.9(woman). All cases were operated on mandible, 3 implants on anterior region and 38 implants on posterior region. 2. The major cause of tooth loss is dental caries(48.8%), followed by periodontal disease. 3. Most distribution of bone qaulity for mandibular implant site was type II(65.8%) and bone quantity was type B(75.6%). 4. The majority of implants were those of 11, 13mm in length(95%) and regular diameter in width (64%). 5. The 41(19 persons) Xive implants that were placed in the mandibular anterior and posterior region were all survival and showed a 100% 2 year cumulative survival rate. The results provided us with basic data on patient type, implant distribution, bone condition, and survival rate. We wish that our results coupled with other research data helps assist in the further study for better implant success rates, etc.

• Proceedings of the Korea Water Resources Association Conference
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• 2010.05a
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• pp.1360-1364
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• 2010

도시유역 물순환 해석 모형(Catchment hydrologic cycle Analysis Tool, CAT)은 기존의 개념적 매개변수 기반의 집중형 수문모형과 물리적 매개변수 기반의 분포형 수문모형의 장점을 최대한 집약하여, 도시유역 개발 전/후의 장/단기적 물순환 변화특성을 정량적으로 평가하고 물순환 개선시설의 효과적인 설계를 지원하기 위한 물순환 해석 모형이다. 이 모형은 수문학적으로 균일하게 판단되는 범위를 소유역으로 분할하여 지형학적 요인에 의한 유출 특성을 객관적으로 반영할 수 있으며, 개발 공간 단위별로 침투, 증발, 지하수 흐름 등의 모의가 가능하도록 하는 링크-노드 방식으로 개발되었다. 모형의 UI(User Interface)는 사용자가 손쉽게 모형을 적용/관리하고, 여러 시나리오를 동시에 효과적으로 모의하여 분석할 수 있도록 설계되었다. 또한, 모든 입/출력 자료를 엑셀이나 텍스트 형식과 연동되도록 하여 프로젝트별 매개변수 관리가 용이하도록 개발하였다. 특히 본 모형에서는 사용자의 목적에 맞는 다양한 물순환 개선시설(침투시설, 저류지, 습지, 빗물저장시설, 리사이클 및 외부급수 등)의 구현 및 모의가 가능하도록 개발하였다. 여기서, 물순환 개선시설이란 빗물을 흡수하고 저류할 수 있는 도시녹지시설 혹은 구조물로서 도심 내의 불투수면을 저감시키고 유출수를 줄이면서 동시에 녹지를 확보하여 효과적인 물순환 기능에 영향을 미치는 시설들이다. 이러한 물순환 개선시설은 신도시 및 지역 혁신도시 개발 등의 대규모 토지이용변화가 예상되는 개발지역에 대한 평가 및 개선 기술을 제공하여 물순환 건전화를 위한 설계에 직접적으로 활용될 수 있는 큰 장점을 지니고 있다. 먼저 침투 시설은 계획침투량을 반영하며 토양으로의 침투량과 지하수로의 이동을 모의한다. 저류시설은 하도 내에 위치한 online 저류지와 하도 외에 위치한 offline 저류지로 구분하고 저류지 수면의 증발량과 취수량을 고려하며, 방류구를 통한 방류량을 반영하였다. offline 저류지의 경우는 하도 내의 흐름의 규모에 따라서 일정량을 넘는 경우만 offline 저류지로 유입될 수 있는 양을 산정하도록 하였으며 하류 하천으로의 방류를 반영하여 홍수 후에 저류지가 비워지도록 하였다. 유역 내의 습지는 식생과 수면에서의 증발산을 반영하였다. 습지의 저류능력을 넘는 양은 월류되어 하류로 유출되며, 방류구를 통한 방류량을 반영하였다. 빗물저장시설의 경우는 초기우수와 같은 일정량 이하의 유입량과 시설용량을 초과하는 양은 방류하도록 하였고, 물 사용량을 반영하였다. 또한, 본 모형에서는 하천 내에서 취수하여 유역으로 공급할 수 있도록 리사이클 처리노드를 계획하였다. 리사이클은 용수 이용 목적에 따라 필요지역으로 공급되는 것으로 하였으며, 하천유지용수의 목적으로 취수되어 상류 혹은 하류의 임의 지역으로 공급되는 것을 포함하였다. 또한, 유역외부에 광역으로 급수되는 공급량도 반영하도록 하였다.

• Journal of Embryo Transfer
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• v.32 no.3
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• pp.171-176
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• 2017

This study was conducted to investigate the breeding status of farms to improve the production efficiency of Hanwoo calf. The study was conducted on 45 farms divided into two groups. This study was conducted to investigate the breeding size and breeding area of Hanwoo cows. The average age at first delivery of Hanwoo was 28.7 months. The number of artificial insemination per pregnancy was $1.45{\pm}0.32$, and the number of artificial insemination days after birth was 119.8 days. Conception rates were $75.2{\pm}16.93%$ for small farms and $70.6{\pm}17.46%$ for medium sized farms and $71.4{\pm}11.03%$ for large farms. When we looked at farming methods, 'the farmers using estrus observation aids' had 10.42% higher calf production rate than the 'unused farmers'. The farms vaccinated with IBR and BVDV for breeding cattle showed a 4.41% decrease in abortion, stillbirth and mortality. According to farming conditions, conception rate and delivery rate improved by 3.47% and 18.29%, respectively, when grazing and exercising were performed. Observation, immunization and grazing were found to be important indicators for improving calf production efficiency in Hanwoo farm. This study can be used as a research data to improve the reproductive rate of farmhouse sites through the survey on the breeding status of Hanwoo farmers.

• Journal of Korean Society of Transportation
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• v.28 no.2
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• pp.65-75
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• 2010

When the cost-benefit analysis is applied for social discount rate(SDR), the choice of SDR to be used in analysis is critical. One of the important issues when public investment project evaluate what is the SDR theory, so there have studied about SDR and no exact answer it so far. In this study, there are three of SDR theories that be estimated social time preference rate, social investment returns and the weighted average method from 1990s, 2000 to 2003 and 2004 to 2008.. First, social time preference method computes consumer's interest rate and the model of Pearce and Ulph(1999). Second, social investment returns method computes private returns of capital. Third, the weighted average method computes the model of Squire, L., Herman G. van der Tak(1975) and private consumption expense and the private investment expense. SDR is estimated in the rage between 2.4% and 3.9% from 2004 to 2008. It is not appropriate that the interest rate was unstable. But it is consider for social equity from present to future generations. Considering this things, downward need to the value of current SDR 5.5%.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.1
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• pp.251-256
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• 2021

This study analyzed the most frequently used navigation cases in a desktop environment. As a result of the research, GNB induces users' search as the top element of the search structure and can place color, text, icon, and image elements. LNB could be classified in the form of a dropdown, flyout, dropline and mega menu. In this study, the navigation structure of Interpark and Interpark among open markets used by users was analyzed. G-Market's GNB has a two-tier structure with color, text, image, and icon elements, and Interpark has a three-tiered horizontal label. Interpark's GNB drew attention by placing a badge on the seasonal label, which is a temporary content section, unlike G-market. It can be seen that the LNBs of both shopping malls have flyout menus that protrude when you mouse over the category menu arranged in a vertical text form under the logo placed on the left. The flyout menu has a complex structure consisting of the layout of the mega menu. This study is meaningful in revealing user experience elements by analyzing the GNB and LNB of shopping malls these days where internet shopping is increasing.

• Animal Bioscience
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• v.35 no.10
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• pp.1545-1555
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• 2022

Objective: Our study aimed to investigate the effects of a 2% increase in dietary total digestible nutrients (TDN) value during the growing (7 to 12 mo of age) and fattening (13 to 30 mo of age) period of Hanwoo steers. Methods: Two hundred and twenty Hanwoo steers were assigned to one of two treatments: i) a control group (basal TDN, BTDN, n = 111 steers, growing = 70.5%, early fattening = 71.0%, late fattening = 74.0%) or high TDN (HTDN, n = 109 steers, growing = 72.6%, early = 73.1%, late = 76.2%). Growth performance, carcass traits, blood parameters, and gene expression of longissimus dorsi (LD) (7, 18, and 30 mo) were quantified. Results: Steers on the BTDN diets had increased (p≤0.02) DMI throughout the feeding trial compared to HTDN, but gain did not differ appreciably. A greater proportion of cattle in HTDN received Korean quality grade 1 (82%) or greater compared to BTDN (77%), while HTDN had a greater yield grade (29%) than BTDN (20%). Redness (a^*) of LD muscle was improved (p = 0.021) in steers fed HTDN. Feeding the HTDN diet did not alter blood parameters. Steers fed HTDN diet increased (p = 0.015) the proportion of stearic acid and tended to alter linoleic acid. Overall, saturated, unsaturated, monounsaturated, and polyunsaturated fatty acids of LD muscle were not impacted by the HTDN treatment. A treatment by age interaction was noted for mRNA expression of myosin heavy chain (MHC) IIA, IIX, and stearoyl CoA desaturase (SCD) (p≤0.026). No treatment effect was detected on gene expression from LD muscle biopsies at 7, 18, and 30 mo of age; however, an age effect was detected for all variables measured (p≤0.001). Conclusion: Our results indicated that feeding HTDN diet could improve overall quality grade while minimum effects were noted in gene expression, blood parameters, and growing performance. Cattle performance prediction in the feedlot is a critical decision-making tool for optimal planning of cattle fattening and these data provide both benchmark physiological parameters and growth performance measures for Hanwoo cattle feeding enterprises.

• Journal of Animal Science and Technology
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• v.65 no.4
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• pp.818-837
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• 2023

Understanding adipocyte development in fetus during bovine pregnancy is important for strengthening fattening technology. Additionally, nutritional level of dams during pregnancy has the potential to improve offspring growth and fat development. The purpose of this study is to evaluate the intramuscular adipocyte development and expression level of related genes in bovine fetus, and the effect of increased crude protein (CP) intake during pregnancy on the growth performance and carcass characteristics of male offspring. Eighty six pregnant Hanwoo cows (average body weight, 551.5 ± 51.3 kg, age 5.29 ± 0.61 y) were used. Fetuses were collected at 90, 180 and 270 d of gestation from 18 pregnant Hanwoo cows. The remaining 68 pregnant cows were randomly assigned to 2 feeding groups. The control (CON) group was provided the standard protein diet (n = 34), and treatment (TRT) group was provided a diet with a 5% increase in CP intake (n = 34). Male offspring were divided into two groups according to protein treatment of the pregnant cows: CON male offspring (CON-O) and TRT male offspring (TRT-O). Intramuscular adipocytes were found in the fetal skeletal muscle after 180 days of gestation. Male calf's birth weight increased in the TRT group compared to that in the CON group (p < 0.002). The final body weight (p < 0.003) and average daily gain (p < 0.019) of male offspring were significantly higher in TRT-O than in CON-O. The feed conversion ratio was also improved by 10.5% in TRT-O compared to that in CON-O (p < 0.026). Carcass weight was significantly higher in the TRT-O group than that in the CON-O group (p < 0.003), and back fat was thicker in the TRT-O group (p = 0.07). The gross receipts and net income were higher in TRT-O than in CON-O (p < 0.04). Thus, fetal intramuscular fat can be formed from the mid-gestation period, and increased CP intake during pregnancy can increase net income by improving the growth and carcass weight of male offspring rather than intramuscular fat.

• Korean Journal of Radiology
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• v.25 no.2
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• pp.146-156
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• 2024

Objective: Automated breast ultrasound (ABUS) is a relevant imaging technique for early breast cancer diagnosis and is increasingly being used as a supplementary tool for mammography. This study compared the performance of ABUS and handheld ultrasound (HHUS) in detecting and characterizing the axillary lymph nodes (LNs) in patients with breast cancer. Materials and Methods: We retrospectively reviewed the medical records of women with recently diagnosed early breast cancer (≤ T2) who underwent both ABUS and HHUS examinations for axilla (September 2017-May 2018). ABUS and HHUS findings were compared using pathological outcomes as reference standards. Diagnostic performance in predicting any axillary LN metastasis and heavy nodal-burden metastases (i.e., ≥ 3 LNs) was evaluated. The ABUS-HHUS agreement for visibility and US findings was calculated. Results: The study included 377 women (53.1 ± 11.1 years). Among 385 breast cancers in 377 patients, 101 had axillary LN metastases and 30 had heavy nodal burden metastases. ABUS identified benign-looking or suspicious axillary LNs (average, 1.4 ± 0.8) in 246 axillae (63.9%, 246/385). According to the per-breast analysis, the sensitivity, specificity, positive and negative predictive values, and accuracy of ABUS in predicting axillary LN metastases were 43.6% (44/101), 95.1% (270/284), 75.9% (44/58), 82.6% (270/327), and 81.6% (314/385), respectively. The corresponding results for HHUS were 41.6% (42/101), 95.1% (270/284), 75.0% (42/56), 82.1% (270/329), and 81.0% (312/385), respectively, which were not significantly different from those of ABUS (P ≥ 0.53). The performance results for heavy nodal-burden metastases were 70.0% (21/30), 89.6% (318/355), 36.2% (21/58), 97.3% (318/327), and 88.1% (339/385), respectively, for ABUS and 66.7% (20/30), 89.9% (319/355), 35.7% (20/56), 97.0% (319/329), and 88.1% (339/385), respectively, for HHUS, also not showing significant difference (P ≥ 0.57). The ABUS-HHUS agreement was 95.9% (236/246; Cohen's kappa = 0.883). Conclusion: Although ABUS showed limited sensitivity in diagnosing axillary LN metastasis in early breast cancer, it was still useful as the performance was comparable to that of HHUS.

• Korean Journal of Radiology
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• v.25 no.6
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• pp.511-517
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• 2024

Objective: To prospectively investigate the influence of the menstrual cycle on the background parenchymal signal (BPS) and apparent diffusion coefficient (ADC) of the breast on diffusion-weighted MRI (DW-MRI) in healthy premenopausal women. Materials and Methods: Seven healthy premenopausal women (median age, 37 years; range, 33-49 years) with regular menstrual cycles participated in this study. DW-MRI was performed during each of the four phases of the menstrual cycle (four examinations in total). Three radiologists independently assessed the BPS visual grade on images with b-values of 800 sec/mm² (b800), 1200 sec/mm² (b1200), and a synthetic 1500 sec/mm² (sb1500). Additionally, one radiologist conducted a quantitative analysis to measure the BPS volume (%) and ADC values of the BPS (ADC_BPS) and fibroglandular tissue (ADC_FGT). Changes in the visual grade, BPS volume (%), ADC_BPS, and ADC_FGT during the menstrual cycle were descriptively analyzed. Results: The visual grade of BPS in seven women varied from mild to marked on b800 and from minimal to moderate on b1200 and sb1500. As the b-value increased, the visual grade of BPS decreased. On b800 and sb1500, two of the seven volunteers showed the highest visual grade in the early follicular phase (EFP). On b1200, three of the seven volunteers showed the highest visual grades in EFP. The BPS volume (%) on b800 and b1200 showed the highest value in three of the six volunteers with dense breasts in EFP. Three of the seven volunteers showed the lowest ADC_BPS in the EFP. Four of the seven volunteers showed the highest ADC_BPS in the early luteal phase (ELP) and the lowest ADC_FGT in the late follicular phase (LFP). Conclusion: Most volunteers did not exhibit specific BPS patterns during their menstrual cycles. However, the highest BPS and lowest ADC_BPS were more frequently observed in EFP than in the other menstrual cycle phases, whereas the highest ADC_BPS was more common in ELP. The lowest ADC_FGT was more frequent in LFP.