• Journal of Energy Engineering
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• v.13 no.1
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• pp.40-50
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• 2004

Treatise that see executed investigation analysis about energy conservation technology, which skill move and skill class of introduction subject, transferㆍintroduction skill form, present condition of technology transferㆍintroduction and necessity etc. to energy conservation technology by program of Korea energy basis plan (1997∼2006) etc. Enforced company which questionnaire object achieves from the end 107 assignment practical used of energy conservation technology development propulsion assignment of Korea energy management corporation (KEMCO) to 1998-200 years and 416 companies related energy saving technology constructed to Korea Institute of Energy Research (KIER) database by post investigation and visit investigation. Question investigation result, transferㆍintroduction fields of energy conservation technology are industry sector, the enterprise size appeared with the fact that the small and medium enteifrise is many most. Also, technology transferㆍintroduction section is plan technique, form with technical cooperative form, amount of money 50,000,000 won under, appeared above 1 years in disturbance duration. In hereafter, technology transferㆍintroduction plan it appeared with the fact that the plan technique is many most.

• International conference on construction engineering and project management
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• 2009.05a
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• pp.1388-1395
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• 2009

In March 2007, Korea's Ministry of Construction & Transportation (MOCT) established "Guidelines on the Computerization and Use of Geotechnical Investigation Results," which took effect as official instructions. The 2007 Geotechnical Information DB Construction Project is underway as a model project for a stable geotechnical information distribution system based on the MOCT guidelines, accompanied by user education on the geotechnical data distribution system. This study introduces a geotechnical data entry system characterized by the standardization of the geotechnical investigation form, the standardization of metadata for creating the geotechnical data to be distributed, and the creation of borehole space data based on the world geodetic system according to the changes in the national coordinate system, to define a unified DB structure and the items for the geotechnical data entry system and to computerize the field geotechnical investigation results using the MOCT guidelines. In addition, the present operating status of the geotechnical data entry system and entry data processing statistics are introduced through an analysis of the model project, and the problems of the project are analyzed to suggest improvements. Education on, and the implementation of, the model project for the geotechnical data entry system, which was developed via the standardization of the geotechnical investigation results form and the metadata for institutions showed that most users can use the system easily. There were problems, however, including those related to the complexity of metadata creation, partial errors in moving to the borehole data window, partial recognition errors in the installation program for different computer operating systems, etc. Especially, the individual standard form usage and the specificity of the person who enters the geotechnical information for the Korea National Housing Corporation, among the institutions under MOCT, required partial improvement of the geotechnical data entry system. The problems surfaced from this study will be promptly addressed in the operation and management of the geotechnical data DB center in 2008.

• The Korean Journal of Ecology
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• v.6 no.4
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• pp.33-59
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• 1983

An investigation has been performed on the flora and life form of the vascular plants at Mt. Sori in Kwangneung from March to November in 1982. In a survey field trip, 539 species, 344 genera, 102 families of plants. are collected. Among them Hylomecon vernale, Aconitum coreanum, A. pseudoproliferum, Adonis amurensis, Anemone raddeana is important plant in this area and they are becoming sparse than past. In the life form spectrum hemiryptophytes is 40.6%.

• YAKHAK HOEJI
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• v.42 no.6
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• pp.576-582
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• 1998

Fenfluramine, an anorectic agent, is widely abused as a diet pill in Korea because it is freely marketed in China without any regulation. The optical isomers of fenfluramine hav e different phamacological actions: d-form is used as an anorectic agent, while l-form as a neuroleptic agent. To investigate the metabolism when racemic fenfluramine was administered orally, the urinary excretion of fenfluramine was studied in rats. The enantiomeric separation of fenfluramine was performed on achiral column by gas chromatography using (S)-N-(trifluoroacetyl)-l-prolyl chloride (TFP) as a derivatizing agent. After administration of 15mg/kg of racemic fenfluramine to rats, d-, l-fenfluramine and its metabolites d- and l norfenfluramine in urine were determined by chromatographic separation of TFP derivatives on DB-1 at retention time of 11.2, 11.8, 8.4 and 8.6 min respectively. Urinary recoveries of d and l-fenfluramine in rat were 0.42-5.9O% and 0.18-1.20% respectively in urine specimens collected during first 24hr. The comparison in the levels of isomers showed that d- fenfluramine were higher than l-form, while d-norfenfluramine were lower than l-form. The ratios between parent compound and metabolite revealed that d-norfenfluramine to d-fenfluramine ranged from 1.0 to 4.4, while the ratio of l-norfenfluramine to l-fenfluramine was 8.2-21.1 indicating that l-fenfluramine is metabolized faster than the d-isomer.

• The Journal of Internal Korean Medicine
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• v.30 no.1
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• pp.181-190
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• 2009

It is important to establish the safety of herbal medicine because of its frequent and widespread use in Korea. Several studies on the safety of herbal medicine have been performed and there have been rare serious adverse drug reactions from those reports in Korea. However, the results are not strongly supported because of not adopting appropriate enough research methodology as to make the safety issue clear. For improving the quality of the safety research on herbal medicine. including investigations of drug induced liver injury (DILl). the aim of this study was to suggest herbal medicine-induced liver injury investigation forms for performing reasonable safety research. After a systematic review of the preceding studies regarding herbal safety in Korea was performed in 2008, we assessed the quality and the limitations of the primary studies. Two investigation forms for herbal safety research were made as a following step. one a basic investigation form for herbal safety research and the other an advanced investigation form for suspected DILl cases, Those forms include the essential informations and data needed to make an appropriate assessment of whether DILl occurred during or after the use of herbal medicine. Guidelines for using those forms and other recommendations were also suggested. More rigorous studies are required for answering the safety issue of herbal medicine as well as the efficacy issue. We hope for wide use and improvement of those investigation forms in the study of herbal safety by many researchers for establishing better evidences in Korea.

• Journal of Pharmaceutical Investigation
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• v.40 no.spc
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• pp.9-17
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• 2010

Polymorphism has been recognized to be a critical issue throughout the drug product development process. Most of solid phase drugs have polymorphism, which has generated a great deal of interest and the field has been evolving rapidly. Preferably, thermodynamically most stable form of a drug substance is selected to obtain consistent bioavailability over its shelf life and various storage conditions. Moreover, it has the lowest potential for conversion from one polymorphic form to another. However, metastable or amorphous forms may be used intentionally to induce faster dissolution rate for rapid drug absorption and higher efficacy. For pharmaceutical industry, polymorphism is one of the key activities in form selection process together with salt selection. This article introduces the main features in the investigation of solid form selection especially polymorphic behavior with thermodynamic backgrounds, physicochemical properties with solubility, dissolution, and mechanical properties, and characterization techniques for proper analysis. The final form can be recommended based on the physicochemical and biopharmaceutical properties and by the processability, scalability and safety considerations. Pharmaceutical scientists especially in charge of formulation need to be well aware of the above issues to assure product quality.

• The Korean Journal of Ecology
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• v.6 no.3
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• pp.187-197
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• 1983

This report is a series of the investigation of the secondary vegetation and succession at the forest fire area in Dangji-Dong of Kyungsang-pookdo province. The forest fires occurred on April 8, 1982. This investigation was carried out from June 18, 1982 to May 29, 1983 once in each season. Before to fires, the Pinus densiflora was dominant and the woody plants of understory were mainly composed of the Quercus serrata, Q. dentata, Lespedeza maritima and L. macimowiczii. Compared with the florstic composition between the unburned and burned areas after the fires, the floristic composition of unburned area comprises: 79 families, 194 genera, 223 species, 26 varieties and 6 formae (255 kinds of vascular plants). The index of similary shows 0.77 (S$\Phi$renson:1948) in this area. The analyses of the life-form compositions in the unburned and burned area show 32.9% and 29.3% in dormancy form (H), 42.4% and 37.7% in disseminule form($D_1$), 80.8% and 82.2% in radicoid form ($R_5$), and 57.7% and 61.8% in erect form(e) respectively. The biological type shows H-$D_1$-R5-e, which is common in both areas, and erect form is generally prevailing in these communities.

• Journal of Pharmaceutical Investigation
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• v.30 no.4
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• pp.289-293
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• 2000

Three polymorphic modifications and one amorphous form were prepared by recrystallization under various conditions and characterized by DSC and X-ray crystallography. At $37{\pm}0.5^{\circ}C$, the polymorphic modifications showed significant differences in the dissolution rate. The dissolution rate of Mod. 4, amorphous form, was faster than that of other polymorphic modifications. When all modifications were stored at 52% RH, 95% RH, and in silica gel desiccator, amorphous form was transformed at 95% humidity condition.

• Journal of Pharmaceutical Investigation
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• v.28 no.2
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• pp.81-85
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• 1998

Three polymorphic modifications and two pseudopolymorphic modifications of cefotaxime sodium were obtained by crystallization from different organic solvents. The isolated crystal forms were characterized by UV spectrophotometry, DSC, TGA and X-ray crystallography. Crystal forms of cefotaxime sodium were also compared by dissolution rate. The dissolution rate of form 1 was the highest, followed by form 2, form 4, form 6, form 5 and form 3. Among these polymorphic modifications the dissolution rate of form 3 and form 5 was much slower than that of cefotaxime sodium on the market. All forms showed no change after 2-month storage test in the silica gel desiccator. But after the storage of 2-month at 95% relative humidity condition, all forms were deliquesced by hygroscopic property except form 1 that showed the highest dissolution rate. At 52% relative humidity condition, form 1, form 2 and form 6 had no evidence of phase transformation, but form 3, form 4 and form 5 were also deliquesced.

• Architectural research
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• v.13 no.4
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• pp.19-30
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• 2011

This investigation, based on empirical research, examined the role of complexity and order in the aesthetic experience of architectural forms. The basic assumption of this study was that perception in architectural form is a process of interpreting a pattern in a reductive way. Thus, perceptual arousal is not determined by the absolute complexity of a configuration. Rather, the actual perceived complexity is a function of the organization of the system (order). In addition, complexity and order were defined and categorized into four variables according to their significant characteristics; simple order, complex order, random complexity, and lawful complexity. The series of experiments confirmed that there is a point on the psychological complexity dimension which is optimal. By demonstrating that consensual and individual aesthetic preference can be measured to have a unimodal function of relationship with complexity, the results of the experiments indicated that complexity and orderliness are effective design factors for enhancing aesthetics of a building facade. This investigation offered a conceptual framework that relates the physical (architectural form) and psychological factors (complexity and order) operating in the aesthetic experience of building facades.