• Title/Summary/Keyword: invariant

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IL-15 in T-Cell Responses and Immunopathogenesis

  • Hoyoung Lee;Su-Hyung Park;Eui-Cheol Shin
    • IMMUNE NETWORK
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    • v.24 no.1
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    • pp.11.1-11.18
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    • 2024
  • IL-15 belongs to the common gamma chain cytokine family and has pleiotropic immunological functions. IL-15 is a homeostatic cytokine essential for the development and maintenance of NK cells and memory CD8+ T cells. In addition, IL-15 plays a critical role in the activation, effector functions, tissue residency, and senescence of CD8+ T cells. IL-15 also activates virtual memory T cells, mucosal-associated invariant T cells and γδ T cells. Recently, IL-15 has been highlighted as a major trigger of TCR-independent activation of T cells. This mechanism is involved in T cell-mediated immunopathogenesis in diverse diseases, including viral infections and chronic inflammatory diseases. Deeper understanding of IL-15-mediated T-cell responses and their underlying mechanisms could optimize therapeutic strategies to ameliorate host injury by T cell-mediated immunopathogenesis. This review highlights recent advancements in comprehending the role of IL-15 in relation to T cell responses and immunopathogenesis under various host conditions.

Improvement of Enhanced Assumed Strain Four-node Finite Element Based on Reissner-Mindlin Plate Theory (개선된 추가변형률 4절점 평판휨 요소)

  • Chun, Kyoung Sik;Park, Dae Yong;Chang, Suk Yoon
    • Journal of Korean Society of Steel Construction
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    • v.16 no.3 s.70
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    • pp.295-303
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    • 2004
  • In this paper, an improved four-node Reissner-Mindlin plate-bending element with enhanced assumed strain field is presented for the analysis of isotropic and laminated composite plates. To avoid the shear locking and spurious zero energy modes, the transverse shear behavior is improved by the addition of a new enhanced shear strain based on the incompatible displacement mode approach and bubble function. The "standard" enhanced strain fields (Andelfinger and Ramm, 1993) are also employed to improve the in-plane behaviors of the plate elements. The four-node quadrilateral element derived using the first-order shear deformation theory is designated as "14EASP". Several applications are investigated to assess the features and the performances of the proposed element. The results are compared with other finite element solutions and analytical solutions. Numerical examples show that the element is stable, invariant, passes the patch test, and yields good results especially in highly distorted regimes.

Molecular Characterization of a Transient Expression Gene Encoding for 1-Aminocyclopropane-1-carboxylate Synthase in Cotton (Gossypium hirsutum L.)

  • Wang, Xia;Zhang, Ying;Zhang, Jiedao;Cheng, Cheng;Guo, Xingqi
    • BMB Reports
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    • v.40 no.5
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    • pp.791-800
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    • 2007
  • Ethylene performs an important function in plant growth and development. 1-aminocyclopropane-1-carboxylate (ACC) synthase (ACS), the key enzyme involved in ethylene biosynthesis, has been the focus of most ethylene studies. Here, a cotton ACS gene referred to as Gossypium hirsutum ACS1 (GhACS1), was isolated. The full-length cDNA of GhACS1 encodes for a 476-amino acid protein which harbors seven conserved regions, 11 invariant amino acid residues, and the PLP binding active site, all of which characterize ACC synthases. Alignment analysis showed that GhACS1 shared a high degree of identity with other known ACC synthases from different species. Two introns were detected in the genomic DNA sequence, and the results of Southern blot analysis suggested that there might be a multi-gene family encoding for ACC synthase in cotton. From the phylogenetic tree constructed with 24 different kinds of ACC synthases, we determined that GhACS1 falls into group II, and was closely associated with the wound-inducible ACS of citrus. The analysis of the 5' flanking region of GhACS1 revealed a group of putative cis-acting elements. The results of expression analysis showed that GhACS1 displayed its transient expression nature after wounding, abscisic acid (ABA), and $CuCl_2$ treatments. These results indicate that GhACS1, which was transiently expressed in response to certain stimuli, may be involved in the production of ethylene for the transmission of stress signals.

A Study on the Improvement of the Facial Image Recognition by Extraction of Tilted Angle (기울기 검출에 의한 얼굴영상의 인식의 개선에 관한 연구)

  • 이지범;이호준;고형화
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.18 no.7
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    • pp.935-943
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    • 1993
  • In this paper, robust recognition system for tilted facial image was developed. At first, standard facial image and lilted facial image are captured by CCTV camera and then transformed into binary image. The binary image is processed in order to obtain contour image by Laplacian edge operator. We trace and delete outermost edge line and use inner contour lines. We label four inner contour lines in order among the inner lines, and then we extract left and right eye with known distance relationship and with two eyes coordinates, and calculate slope information. At last, we rotate the tilted image in accordance with slope information and then calculate the ten distance features between element and element. In order to make the system invariant to image scale, we normalize these features with distance between left and righ eye. Experimental results show 88% recognition rate for twenty five face images when tilted degree is considered and 60% recognition rate when tilted degree is not considered.

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Joint Tx-Rx Optimization in Additive Cyclostationary Noise with Zero Forcing Criterion (가산성 주기정상성 잡음이 있을 때 Zero Forcing 기반에서의 송수신단 동시 최적화)

  • Yun, Yeo-Hun;Cho, Joon-Ho
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.32 no.7A
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    • pp.724-729
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    • 2007
  • In this paper, we consider a joint optimization of transmitter and receiver in additive cyclostationary noise with zero forcing criterion. We assume that the period of the cyclostationary noise is the same as the inverse of the symbol transmission rate and that the noise has a positive-definite autocorrelation function. The data sequence is modeled as a wide-sense stationary colored random process and the channel is modeled as a linear time-invariant system with a frequency selective impulse response. Under these assumptions and a constraint on the average power of the transmitted signal, we derive the optimum transmitter and receiver waveforms that jointly minimizes the mean square error with no intersymbol interference. The simulation results show that the proposed system has a better BER performance than the systems with receiver only optimization and the systems with no transmitter and receiver optimization.

A Study on Illumination Normalization Method based on Bilateral Filter for Illumination Invariant Face Recognition (조명 환경에 강인한 얼굴인식 성능향상을 위한 Bilateral 필터 기반 조명 정규화 방법에 관한 연구)

  • Lee, Sang-Seop;Lee, Su-Young;Kim, Joong-Kyu
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.47 no.4
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    • pp.49-55
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    • 2010
  • Cast shadow caused by an illumination condition can produce troublesome effects for face recognition system using reflectance image. Consequently, we need to separate cast shadow area from feature area for improvement of recognition accuracy. A Bilateral filter smooths image while preserving edges, by means of a nonlinear combination of nearby pixel values. Processing such characteristics, this method is suited to our purpose in illumination estimation process based on Retinex. Therefore, in this paper, we propose a new illumination normalization method based on the Bilateral filter in face images. The proposed method produces a reflectance image that is preserved relatively exact cast shadow area, because coefficient of filter is designed to multiply proximity and discontinuity of pixels in input image. Performance of our method is measured by a recognition accuracy of principle component analysis(PCA) and evaluated to compare with other conventional illumination normalization methods.

A Feature-Based Retrieval Technique for Image Database (특징기반 영상 데이터베이스 검색 기법)

  • Kim, Bong-Gi;Oh, Hae-Seok
    • The Transactions of the Korea Information Processing Society
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    • v.5 no.11
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    • pp.2776-2785
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    • 1998
  • An image retrieval system based on image content is a key issue for building and managing large multimedia database, such as art galleries and museums, trademarks and copyrights, and picture archiving and communication system. Therefore, the interest on the subject of content-based image retrieval has been greatly increased for the last few years. This paper proposes a feature-based image retrieval technique which uses a compound feature vector representing both of color and shape of an image. Color information for the feature vector is obtained using the algebraic moment of each pixel of an image based on the property of regional color distribution. Shape information for the feature vector is obtained using the Improved Moment Invariant(IMI) which reduces the quantity of computation and increases retrieval efficiency. In the preprocessing phase for extracting shape feature, we transform a color image into a gray image. Since we make use of the modified DCT algorithm, it is implemented easily and can extract contour in real time. As an experiment, we have compared our method with previous methods using a database consisting of 150 automobile images, and the results of the experiment have shown that our method has the better performance on retrieval effectiveness.

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A Design Methodology for CNN-based Associative Memories (연상 메모리 기능을 수행하는 셀룰라 신경망의 설계 방법론)

  • Park, Yon-Mook;Kim, Hye-Yeon;Park, Joo-Young;Lee, Seong-Whan
    • Journal of KIISE:Software and Applications
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    • v.27 no.5
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    • pp.463-472
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    • 2000
  • In this paper, we consider the problem of realizing associative memories via cellular neural network(CNN). After introducing qualitative properties of the CNN model, we formulate the synthesis of CNN that can store given binary vectors with optimal performance as a constrained optimization problem. Next, we observe that this problem's constraints can be transformed into simple inequalities involving linear matrix inequalities(LMIs). Finally, we reformulate the synthesis problem as a generalized eigenvalue problem(GEVP), which can be efficiently solved by recently developed interior point methods. Proposed method can be applied to both space varying template CNNs and space-invariant template CNNs. The validity of the proposed approach is illustrated by design examples.

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SLNR-based User Scheduling in Multi-cell networks: from Multi-antenna to Large-Scale Antenna System

  • Li, Yanchun;Zhu, Guangxi;Chen, Hua;Jo, Minho;Liu, Yingzhuang
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.8 no.3
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    • pp.945-964
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    • 2014
  • In this paper, we investigate the performance of Signal to Leakage and Noise Radio (SLNR) based user scheduling in uplink of multi-cell with large-scale antenna system. Large antenna array is desired to improve the performance in future system by providing better beamforming capability. However, some studies have found that the signal channel is 'hardened' (becomes invariant) when the antenna number goes extremely large, which implies that the signal channel aware user scheduling may have no gain at all. With the mathematic tool of order statistics, we analyzed the signal and interference terms of SLNR in a homogeneous multicell network. The derived distribution function of signal and interference shows that the leakage channel's variance is much more influential than the signal channel's variance in large-scale antenna regime. So even though the signal channel is hardened, the SLNR-based scheduling can achieve remarkable multiuser diversity (MUD) gain due to the fluctuation of the uplink leakage channel. By providing the final SINR distribution, we verify that the SLNR-based scheduling can leverage MUD in a better way than the signal channel based scheduling. The Monte Carlo simulations show that the throughput gain of SLNR-based scheduling over signal channel based scheduling is significant.

Automatic Co-registration of Cloud-covered High-resolution Multi-temporal Imagery (구름이 포함된 고해상도 다시기 위성영상의 자동 상호등록)

  • Han, You Kyung;Kim, Yong Il;Lee, Won Hee
    • Journal of Korean Society for Geospatial Information Science
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    • v.21 no.4
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    • pp.101-107
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    • 2013
  • Generally the commercial high-resolution images have their coordinates, but the locations are locally different according to the pose of sensors at the acquisition time and relief displacement of terrain. Therefore, a process of image co-registration has to be applied to use the multi-temporal images together. However, co-registration is interrupted especially when images include the cloud-covered regions because of the difficulties of extracting matching points and lots of false-matched points. This paper proposes an automatic co-registration method for the cloud-covered high-resolution images. A scale-invariant feature transform (SIFT), which is one of the representative feature-based matching method, is used, and only features of the target (cloud-covered) images within a circular buffer from each feature of reference image are used for the candidate of the matching process. Study sites composed of multi-temporal KOMPSAT-2 images including cloud-covered regions were employed to apply the proposed algorithm. The result showed that the proposed method presented a higher correct-match rate than original SIFT method and acceptable registration accuracies in all sites.