• Title/Summary/Keyword: intestinal pathology

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Segmental Dilatation of the Ileum Combined with Colonic Duplication: - a Case Report - (대장 중복증과 동반된 회장 분절 확장증 1례)

  • Han, Seok-Joo;Kim, Seung-Min;Son, Soeg-U;Kim, Ho-Geun;Kim, Jai-Eok;Hwang, Eui-Ho
    • Advances in pediatric surgery
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    • v.4 no.2
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    • pp.166-171
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    • 1998
  • Segmental dilatation of the small intestine is a rare form of the congenital intestinal anomaly. Many other combined anomalies have been reported in, but the association with colonic duplication has not been reported in the literature. We report a case of segmental dilatation of the distal ileum associated with colonic duplication. The main clinical and pathogenic aspects are discussed, and the literatures are reviewed.

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Synchronous ileal inflammatory fibroid polyp and Meckel's diverticulum found during laparoscopic surgery for adult intussusception

  • Kang, Sung Il;Gu, Mi Jin
    • Journal of Yeungnam Medical Science
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    • v.37 no.3
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    • pp.226-229
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    • 2020
  • We present a rare case of synchronous ileal inflammatory fibroid polyp and Meckel's diverticulum detected during laparoscopic surgery for adult intussusception. A 48-year-old woman presented with sudden onset of severe abdominal pain. Abdominal computed tomography revealed a segment of ileocecal intussusception. Thus, laparoscopic exploration was performed, which revealed an ileal mass with an outpouching closed luminal structure in the distal ileum. Two abnormal structures were resected via mini-laparotomy, and the patient was discharged without postoperative complications. Histopathological examination confirmed an ileal inflammatory fibroid polyp and Meckel's diverticulum with ectopic pancreatic tissue.

Histochemical Properties Study on the Mucosubstances of the Intestinal Mucosa in the Raja kenojei (홍어 장점막 점액의 조직화학적 성상에 관한 연구)

  • Joo, Kyeng Woong
    • Korean Journal of Clinical Laboratory Science
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    • v.36 no.2
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    • pp.173-177
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    • 2004
  • This study is performed in order to clarify the histochemical structure, the distribution of mucous cell and goblet cell, and the histochemical properties of the mucosubstances in the middle region of intestinal mucosa and rectum of Raja kenojei. In the H&E stain, distribution of the mucous cells and acidophilic cells were a more compacted middle portion than other regions of intestine, but the former was more than the latter in the number of mucous cells to rectum. The mucosubstances were stained with aldehyde fuchsin pH 1.7-alcian blue(pH 2.5) stain and then compared to distribution of the mucosubstances used in image and microscope technology(IMT-Size5). The middle intestine of Raja kenojei was composed of mucous cells having only large amounts of mucosubstances in the distal region was much more than that of proximal region. It was two types of mucous cells to rectum, one type was the same as proximal intestine while the other had small amounts of weakly sulfated and large amounts of carboxylated mucins.

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Gizzard impaction and duodenal perforation in a yellow-billed spoonbill (Platalea leucorodia)

  • Ho-Seong, Cho;Yeonsu, Oh
    • Korean Journal of Veterinary Service
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    • v.45 no.4
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    • pp.331-335
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    • 2022
  • A yellow-billed spoonbill kept at the zoo was found dead. As a result of the necropsy, the stomach (gizzard and proventriculus) and duodenum were full of undigested fish bones, and the undigested sharp fish bones were lodged in the gastric mucosa and clumped together, blocking the lumen. Thereafter, the intestinal wall was perforated and peritonitis occurred causing death. The cause of the fish spines becoming lodged in the gastrointestinal tract is unknown. It can only be assumed that there was a lack of a mechanism for the yellow-billed spoonbill in a zoo to go around and pick up grit or small stones and assist in mechanical crushing in the gizzard.

Intestinal Lymphangiectasia in a Yorkshire terrier Dog: Clinical Outcome, Clinicopathological and Histopathological Findings (요크셔테리어견에서 발생한 Intestinal Lymphangiectasia: 임상적 결과와 임상병리학적, 조직병리학적 소견)

  • Hwang Du-Na;Park Chul;Kang Byeong-Teck;Jeong Soon-Wuk;Sur Jung-Hyang;Park Hee-Myung
    • Journal of Veterinary Clinics
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    • v.23 no.2
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    • pp.175-179
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    • 2006
  • A 7-year-old, 3.16 kg intact male Yorkshire terrier had the history of abdominal distension, diarrhea, and weight loss. On the basis of history takings, physical examination, laboratory tests, radiography, ultrasonography, exploratory laparotomy, and histopathological examination, the dog was diagnosed definitely as intestinal lymphangiectasia. In this case, signs and results are consistent with those of other reports, but some clinicopathological findings such as hypocalcemia and hypocholesterolemia are not. This means that the findings were not completely in accord with the typical ones of intestinal lymphangiectasia in this dog. Prednisolone was prescribed to treat. However, it was not effective sufficiently. Thus, azathioprine was added to the regimen used in the first trial, and it was quite efficient in inducing remission in intestinal lymphangiectasia. The clinical signs were improved to the combined therapy. This case report demonstrates that the combined therapy for intestinal lymphangiectasia can be used as an alternative to only glucocorticoid therapy.

The Prevalence of Atrophic Gastritis and Intestinal Metaplasia according to Gender, Age and Helicobacter Pylori Infection in a Rural Population (한 농촌지역 주민에서 성, 연령 및 Helicobacter pylori 감염 여부에 따른 위축성 위염과 장상피화생 유병률)

  • Kim, Hyun-Ja;Choi, Bo-Youl;Byun, Tae-Joon;Eun, Chang-Soo;Song, Kyu-Sang;Kim, Yong-Sung;Han, Dong-Soo
    • Journal of Preventive Medicine and Public Health
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    • v.41 no.6
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    • pp.373-379
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    • 2008
  • Objectives ; The objective of this study was to evaluate the prevalence of atrophic gastritis and intestinal metaplasia according to gender, age and Helicobacter pylori infection in a rural population in Korea. Methods: Between April 2003 and January 2007, 713 subjects (298 men and 415 women, age range: 18-85) among the 2,161 adults who participated in a population-based survey received gastrointestinal endoscopy. All the subjects provided informed consent. Multiple biopsy specimens were evaluated for the presence of atrophic gastritis and intestinal metaplasia. The presence of Helicobacter Pylori was determined using CLO and histology testing. Results ; The age-adjusted prevalence of atrophic gastritis was 42.7% for men and 38.1% for women and the prevalence of intestinal metaplasia was 42.5% for men and 32.7% for women. The prevalence of atrophic gastritis and intestinal metaplasia increased significantly with age for both men and women (p for trend<0.001). The age-adjusted prevalence of Helicobacter pylori was similar for men (59.0%) and women (56.7%). The subjects with Helicobacter pylori infection showed a significantly higher prevalence of intestinal metaplasia (44.3%) compared with that (26.8%) of the noninfected subjects (p<0.001). However, the prevalence of atrophic gastritis was not statistically different between the Helicobacter pylori-infected subjects and the noninfected individuals. Conclusions : Our findings suggest that the prevalence of atrophic gastritis and intestinal metaplasia is higher for a Korean rural population than that for a Western population; this may be related to the high incidence of gastric cancer in Koreans. Especially, the prevalence of intestinal metaplasia was high for the subjects with Helicobacter pylori infection. The multistep process of gastric carcinogenesis and the various factors contributing to each step of this process need to be determined by conducting future follow-up studies.

The Study on the Process and Quality Control of Rhus Verniciflua Stokes Extract (Nexia) (이공산(異功散)의 혈관신생(血管新生) 및 암전이(癌轉移) 억제효과(抑制效果)에 관한 연구(硏究))

  • Kang, Chang-Hee;Kang, Hee;Shin, Hyeun-Kyoo;;Kim, Sung-Hoon;Choi, Seung-Hoon;Ahn, Kyoo-Seok
    • Journal of Korean Traditional Oncology
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    • v.11 no.1
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    • pp.41-54
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    • 2006
  • Ekongsan (EKS) was expected to have inhibitory effects on angiogenesis, considering the fact that its constituents such as Ginseng Radix, Glycyrrhizae Radix and Citri Pericarpium were reported to inhibit angiogenesis. Moreover, recently several metabolites transformed by the human intestinal microflora were reported to enhance effectiveness compared to their crude drugs. Based on these data, this study was designed to confirm whether the EKS metabolites (EKS-M) can significantly exert the anti-angiogenic and anti-metastatic activites. Hence, with EKS and EKS-M, viability assay, proliferation assay, in vitro tube formation assay, gelatin zymogram assay, in vitro invasion assay were carried out. EKS showed less toxicity in ECV304 and HT1080 cells than EKS-M. EKS-M inhibited the proliferation of HT1080 cells by 30% at 200 ${\mu}g/m{\ell}$ and 42% at 400 ${\mu}g/m{\ell}$ respectively. Also, EKS-M degraded the tube network at 200 ${\mu}g/m{\ell}$. EKS and EKS-M inhibited the expression of MMP-9 at 200 and 400 ${\mu}g/m{\ell}$in HT1080 cells. EKS reduced the invasive activity of HT1080 cells through matrigel coated transfilter at the concentration of 200 ${\mu}g/m{\ell}$ more effectively than EKS-M. These data suggest that EKS and EKS-M has anti-angiogenic and anti-metastatic activities.

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The helminthic parasites of greenling, hexagrammos otakii Jordan et Starks, from the Korean southern sea (한국 남해안산 쥐노래미에 기생하는 연충류)

  • Kim, Ki-Hong;Huh, Sung-Hoi;Ji, Bo-Young
    • Journal of fish pathology
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    • v.10 no.2
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    • pp.137-142
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    • 1997
  • A monogenean gill parasite, Prosomicrocotyla gotoi, and a digenean intestinal fluke. Opecoelus sphaericus, were found from greenilngs (Hexagrammos otakii) captured at the Korean southern sea. P. gotoi was characterized by having two separated frills of opisthaptor and distinguished from P. chirii in testis and clamp numbers. O. sphaericus had three pairs of finger-like marginal appendages on the ventral sucker and the parasite was distinguished from O. nipponicus in the location pattern of testes. These two helminth species were the first recording species in Korea.

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Gnathostoma hispidum Infection in a Korean Man Returning from China

  • Kim, Han-Seong;Lee, Jin-Joo;Joo, Mee;Chang, Sun-Hee;Chi, Je-G.;Chai, Jong-Yil
    • Parasites, Hosts and Diseases
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    • v.48 no.3
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    • pp.259-261
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    • 2010
  • Human Gnathostoma hispidum infection is extremely rare in the world literature and has never been reported in the Republic of Korea. A 74-year-old Korean man who returned from China complained of an erythematous papule on his back and admitted to our hospital. Surgical extraction of the lesion and histopathological examination revealed sections of a nematode larva in the deep dermis. The sectioned larva had 1 nucleus in each intestinal cell and was identified as G. hispidum. The patient recalled having eaten freshwater fish when he lived in China. We designated our patient as an imported G. hispidum case from China.

Chemopreventive Effects of Ginseng on Rat Carcinogenesis

  • Wanibuchi Hideki;Ichihara Toshio;Morimura Keiichirou;Fukushima Shoji
    • Proceedings of the Ginseng society Conference
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    • 2002.10a
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    • pp.277-287
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    • 2002
  • The chemopreventive effects of ginseng on rat carcinogenesis models were investigated, In the present study, the inhibitory effects of white and red ginseng on tumor development were examined using medium-term liver, initiation and medium-term multi-organ carcinogenicity bioassay systems. No modifying potential of the ginsengs was evident in terms of the numbers or areas of glutathione S-transferase placental form (GST -P)-positive foci, which is a marker of preneoplastic lesion in rat livers. However, white ginseng, but not red ginseng was found to decrease the incidences of adenocarcinoma of the small intestine and colon in the medium-term multi-organ carcinogenesis model. These results indicate that white ginseng may have inhibitory effects on progression stage of rat intestinal carcinogenesis, but the influence is not strong. Ginseng is unlikely to have promoting or inhibitory effects in other organs under the present type of experimental conditions. Possible application on ginseng for chemoprevention of colon cancer in humans, can be concluded given the lack of obvious adverse effects.

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