• 대한한의학회지
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• 제33권3호
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• pp.120-132
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• 2012

Objectives: This study aimed to analyze the current status of treatments and patients with interstitial cystitis, and then map out a strategy for development of generalized-treatments for interstitial cystitis in Traditional Korean Medicine. Methods: We selected research paper from various databases such as PubMed, Google, KStudy, KoreanTK, OIM, and KOMS. Also, to understand current tendencies of medical cost related with interstitial cystitis, we requested Health Insurance Review and Assessment Service clinical data from 2007 to 2011. Results: It was reported that treatment of interstitial cystitis using Traditional Korean Medicine was effective. However, patients of this usually visit a Western medical center rather than seek Traditional Korean Medicine. To take charge of clinical fields related with interstitial cystitis by Traditional Korean Medicine, we need more research and experiments of interstitial cystitis using Traditional Korean Medicine, and we must make a standardized protocol. Conclusions: Various studies related with interstitial cystitis using Traditional Korean Medicine will have to be undertaken. We expect that Traditional Korean Medicine will play a role in treatment of interstitial cystitis.

• Journal of Acupuncture Research
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• 제29권2호
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• pp.107-113
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• 2012

Objectives : The purpose of this study was to evaluate the effects of $Sa-am$ acupuncture treatment on an interstitial cystitis patient. Methods : A 51 year-old woman who diagnosed as interstitial cystitis, was enrolled in this study. The clinical data was analyzed on a patient with interstitial cystitis due to $Shinheo$(腎虛). The patient had visited Korean medicine department of Yangsan public health care center, and was treated with a $Sa-am$ acupuncture($Sinjeongkyeok$) for 4 weeks. Results : After 4 weeks of $Sa-am$ acupunture treatment($Sinjeongkyeok$), improvement was seen in the subsection of the international prostate symptom score and the part of qualiveen questionnaire score. Conclusions : This clinical case indicates that acupuncture treatment is significantly effective in treatment of a interstitial cystitis.

• 대한한방부인과학회지
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• 제32권3호
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• pp.86-101
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• 2019

Objectives: This review is aimed at assessing the efficacy and effectiveness of acupuncture treatment for interstitial cystitis patients through literature research and overview. Methods: Database searching was conducted to identify relevant randomized controlled trials (RCTs) and clinical studies on the acupuncture treatment for interstitial cystitis patients. Studies were searched from Journal of Korean Obstetrics and Gynecology, KISS, KMBASE, CNKI, Cochrane library, PubMed and EmBase up to April 2019. Results: Five studies including three RCTs and two clinical studies were finally selected. Three studies showed that acupuncture was effective for interstitial cystitis. One study showed ineffectiveness of acupuncture treatment. Conclusions: From three studies, acupuncture treatment for interstitial cystitis patients showed symptoms relief and improvement of QoL (Quality of Life). Further strictly designed studies are needed to confirm the efficacy and setup the acupuncture treatment protocol.

• 대한한방내과학회지
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• 제33권2호
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• pp.222-230
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• 2012

Background : Interstitial cystitis is a disorder of the bladder characterized by urgency and frequency of urination, and pelvic pain. The cause of interstitial cystitis is not clear. Modern medical treatments include behavioral therapy, medication, intravesical infusion therapy, and surgical treatment, but the goal of treatment is based on symptom relief rather than a cure. According to a recent report, in an animal model, oriental medicine treatment, Yukmijihwang-tang improved the symptoms of interstitial cystitis. However, clinical studies and experimental research are lacking. Objectives : In this study, We investigated Chuknyojetong-tang, acupuncture, moxibustion and bee venom effect on interstitial cystitis. Methods : We targeted 25 patients diagnosed with interstitial cystitis at the university hospital and treated them for more than one month. We used acupuncture, Chuknyojetong-tang, and bee venom. The effects were evaluated using ICSI and ICPI at the begin of treatment and at the end of treatment. Results : All of the 25 patients were female, average age was $53.3{\pm}13.5$ years, and the average month of disease-duration was $69.0{\pm}59.8$. The duration of treatment was $8.0{\pm}5.4$ months, and 60% of patients were improved. After treatment, we used correlation coefficient method, multiple regression analysis. ICSI difference increased as treatment period increased. ICPI difference increased as age decreased. Total difference also increased as treatment period increased. These results imply that treatment effect was improved. Conclusions : These findings suggest that oriental medicine therapy using Chuknyojetong-tang, acupuncture, moxibustion, and bee venom would be very effective on interstitial cystitis.

• 대한한방부인과학회지
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• 제34권1호
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• pp.82-92
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• 2021

Objectives: The purpose of this study is to report the clinical effectiveness of Korean medicine treatment on interstitial cystitis. Methods: The patient diagnosed with Interstitial cystitis/Bladder pain syndrome (IC/BPS) was treated with Korean medicine treatment during 22 days of hospitalization. The patient received Korean medicine treatment including herbal medicine, acupuncture, pharmacopuncture, moxibustion, cupping and extracorporeal magnetic stimulation therapy. The effect of treatment on IC/BPS was evaluated through the Numeric Rating Scale (NRS), voiding diary, and Interstitial Cystitis Symptom Index/Problem Index (ICSI/ICPI). Results: After the treatment, the clinical symptoms of IC/BPS such as pelvic pain, pelvic pressure, frequent urination and urinary urgency were improved. Also, the patient had better scores in ICSI/ICPI. Conclusions: This case report proved that the Korean medicine treatment may be effective for improving clinical symptoms of IC/BPS. However, a large-scale clinical study is needed in the future to prove the effectiveness of Korean medicine treatment for IC/BPS.

• The Korean Journal of Pain
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• 제18권2호
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• pp.208-209
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• 2005

Interstitial cystitis is an extremely painful and distressing condition, characterized by severe suprapubic pain, which increases with bladder filling and is relieved by voiding. The daily frequency of micturition may approach 100 times, but no incontinence is observed. The symptoms persist throughout the night, which consequently affects sleep. The etiology of this condition is still unknown, but includes infection, autoimmune response, allergic reaction, neurogenic inflammation, epithelial dysfunction and inherited susceptibility. Herein, a case of interstitial cystitis, with severe symptoms, which was successfully treated with lumbar sympathetic block, is reported.

• 여성건강간호학회지
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• 제15권4호
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• pp.381-386
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• 2009

Interstitial Cystitis/Painful Bladder Syndrome: Prevalence Estimates, Quality of Life and Depression among Older Adult Korean Women. What is already known about the topic? 1) Interstitial Cystitis/Painful bladder syndrome (IC/PBS) is a chronic, painful, inflammatory condition of the bladder wall. 2) Previous studies examining the prevalence and impact were focused on middle life women and not elderly women. 3) Epidemiologic studies of IC/PBS have been predominantly conducted in Western countries and little research reported in Asian countries.

• International Neurourology Journal
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• 제22권4호
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• pp.246-251
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• 2018

Purpose: To determine whether responses to serotonin are altered in bladder strips from cats diagnosed with a naturally occurring form of bladder pain syndrome/interstitial cystitis termed feline interstitial cystitis (FIC). Methods: Full thickness bladder strips were isolated from aged matched healthy control cats and cats with clinically verified FIC. Bladder strips were mounted in an organ bath and connected to a tension transducer to record contractile activity. A serotonin dose response ($0.01-10{\mu}M$) was determined for each strip with the mucosa intact or denuded. Results: Bladder strips from control and FIC cats contracted in response to serotonin in a dose-dependent manner. The normalized force of serotonin-evoked contractions was significantly greater in bladder strips from cats with FIC (n=7) than from control cats (n=4). Removal of the mucosa significantly decreased serotonin-mediated responses in both control and FIC bladder preparations. Furthermore, the contractions in response to serotonin were abolished by $1{\mu}M$ atropine in both control and FIC bladder strips. Conclusions: The effect of serotonin on contractile force, but not sensitivity, was potentiated in bladder strips from cats with FIC, and was dependent upon the presence of the mucosa in control and FIC groups. As atropine inhibited these effects of serotonin, we hypothesize that, serotonin enhances acetylcholine release from the mucosa of FIC cat bladder strips, which could account for the increased force generated. In summary, FIC augments the responsiveness of bladder to serotonin, which may contribute to the symptoms associated with this chronic condition.

• 대한상한금궤의학회지
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• 제12권1호
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• pp.161-169
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• 2020

Objective: This case report describes the improvements of a patient with recurrent cystitis who was treated using an herbal medication according to the Shanghanlun disease pattern identification diagnostic system (DPIDS). Methods: 'DPIDS'and 'Interpretation based on Etymological chinese characters,'the patient was diagnosed with Shaoyin-bing, provision number 315, and administered Baektong-tang herb medication for 30 days. The changes in the symptoms of recurrent cystitis were estimated using the Interstitial Cystitis Symptom Index and Problem Index-Korean version (ICSI/ICPI-K) and Visual Analogue Scale (VAS). Results : The ICSI/ICPI-K score changed from 33 to 0 and VAS score changed from 7 to 0. Conclusions: The main causes of the disease were 微 and 利,and the symptoms of recurrent cystitis

• Journal of Acupuncture Research
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• 제18권4호
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• pp.212-220
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• 2001

간질성 방광염이란 성인여성에게 생기는 질환으로 일종의 근육에 생긴 염증이며 미국에서는 아주 흔한 질환이나 국내에서는 그 동안 진단기준이 없어 단순한 방광염으로 오인 되어왔다. 증상은 일반적인 방광염과 비슷하나 너무 자주 재발하고 잘 낫지 않으며 방광용적의 감소로 빈뇨와 급뇨, 하복부와 회음부의 통증이 흔하고 방광을 비우면 증상은 호전되는 양상을 보인다. 진단을 확진할 정확한 검사가 없기 때문에 반드시 다른 질환이 없슴을 증명하여야 한다. 즉 방광염을 일으키는 원인들인 요로 감염, 골반염, 결핵, 결석, 성병, 전립선염, 방광암 등이 없이 빈뇨와 소변을 참지 못하고 하복통이 있을 때 일단 의심을 하고 방광내시경상에 방광 벽의 염증이나 점상성 출혈, 궤양이 있으면 확진한다. 양방에서는 한가지 완벽한 치료가 없어 여러 가지 복합적인 치료를 하며 일차적으로는 약물요법과 방광확장술을 시도한다. 먹는 약으로는 아직 공인된 것은 없으며 이 약들은 증상의 호전은 기대할 수 있으나 일시적인 경우가 많으며 결국은 방광확장술을 추가하는 경우가 대부분이다. 이에 이 질환을 갖고 있는 여자 환자에게 침 치료를 시행한 결과 주관적인 통증과 급박감에 있어서 감소와 객관적인 소변 횟수의 감소에 있어 만족할 만한 효과를 얻었기에 보고하는 바이다.