• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.3
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• pp.546-550
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• 2011

The aim of this study was to evaluate oriental medicine pattern identification in patients with stroke on the basis of plasma fibrinogen levels and platelet counts. 555 patients diagnosed with stroke between November 2006 and February 2010 were divided in several ways according to the plasma fibrinogen levels and platelet counts on admission. And comparative analysis of the distribution ratio of oriental medicine pattern identification was done between the groups. The mean value of the plasma fibrinogen levels of whole population was 449.18 mg/dL, and it was higher than normal range. The mean value of the platelet counts of whole population was 244.29 /mL, and it was lower but in normal range. Oriental medicine pattern identifications were not characteristic between groups divided according to the serum levels of fibrinogen and platelet counts. In this study, there was not significant correlation between Oriental medicine pattern identifications and the thrombotic factor like plasma fibrinogen levels and platelet counts. This study could be the steppingstone for the next study to develope the objective indicator for the Oriental medicine pattern identifications.

• The Korean Journal of Nuclear Medicine
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• v.24 no.1
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• pp.93-100
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• 1990

To evaluate the utility of autoradiographic technique in the detection of TRH receptor changes in brain after the various kinds of stimulation or drug administration, we tried the characterization of TRH receptor in mouse brain and autoradiography in rat brain as a preliminary study. The Kd value of [3-H] MeTRH to TRH receptors of adult male ICR mouse brain (cebellum and spinal cord were excluded) was 3.55+0.6 nM and Bmax was 3.44+0.52 fmol/mg wet tissue by saturation analysis. The Kd value of TRH to TRH receptors was 133.8+28.2 nM by competition analysis. And we could visualize the distribution of TRH receptors in rat brain by autoradiographic technique.

• Gut and Liver
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• v.12 no.6
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• pp.641-647
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• 2018

Background/Aims: Helicobacter pylori eradication rates are decreasing because of increases in clarithromycin resistance. Thus, finding an easy and accurate method of detecting clarithromycin resistance is important. Methods: We evaluated 70 H. pylori isolates from Korean patients. Dual-labeled peptide nucleic acid (PNA) probes were designed to detect resistance associated with point mutations in 23S ribosomal ribonucleic acid gene domain V (A2142G, A2143G, and T2182C). Data were analyzed by probe-based fluorescence melting curve analysis based on probe-target dissociation temperatures and compared with Sanger sequencing. Results: Among 70 H. pylori isolates, 0, 16, and 58 isolates contained A2142G, A2143G, and T2182C mutations, respectively. PNA probe-based analysis exhibited 100.0% positive predictive values for A2142G and A2143G and a 98.3% positive predictive value for T2182C. PNA probe-based analysis results correlated with 98.6% of Sanger sequencing results (${\kappa}$-value=0.990; standard error, 0.010). Conclusions: H. pylori clarithromycin resistance can be easily and accurately assessed by dual-labeled PNA probe-based melting curve analysis if probes are used based on the appropriate resistance-related mutations. This method is fast, simple, accurate, and adaptable for clinical samples. It may help clinicians choose a precise eradication regimen.

• Korean Chemical Engineering Research
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• v.52 no.3
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• pp.347-354
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• 2014

Economic evaluation of the manufacturing technology of high-value chemicals through the carbonation reaction of carbon dioxide contained in the flue gas was performed, and analysis of the IRR (Internal Rate of Return) and whole profit along the production plan of the final product was conducted. Through a carbonation reaction with sodium hydroxide that is generated from electrolysis and by using carbon dioxide in the combustion gas that is generated in the power plant, it is possible to get a high value products such as sodium bicarbonate compound and also to reduce the carbon dioxide emission simultaneously. The IRR (Internal Rate of Return) and NPV (Net Present Value) methods were used for the economic evaluation of the process which could handle carbon dioxide of 100 tons per day in the period of the 20 years of plant operation. The results of economic evaluation showed that the IRR of baseline case of technology was 67.2% and the profit that obtained during the whole operation period (20 years) was 346,922 million won based on NPV value. When considering ETS due to the emissions trading enforcement that will be activated in 2015, the NPV was improved to a 6,000 million won. Based on this results, it could be concluded that this $CO_2$ carbonation technology is an cost-effective technology option for the reduction of greenhouse gas.

• Tuberculosis and Respiratory Diseases
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• v.45 no.5
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• pp.1000-1011
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• 1998

Background: For the diagnosis or evaluation of airway obstruction in bronchial asthma and chronic obstructive lung disorders, various parameters derived from the forced expiratory volume curve and maximal expiratory flow volume curve have been used. Recently the peak expiratory flow(PEF) measured by the peak flow meter is widely used because of its simplicity and convenience. But there were still no data of the predicted normal values measured by the peak flow meter in Korea. This study was to obtain the predicted normal value of PEF and to know the accuracy of this value to predict $FEV_1$. Method: The measurements of PEF by the MiniWright peak flow meter and several parameters derived from the forced expiratory volume and maximal expiratory flow volume curves by the Microspiro HI 501(Chest Co.) were done in 129 men and 125 women without previous history of the respiratory diseases. The predicted normal values of parameters according to the age and the height were obtained, and the regression equation of $FEV_1$ by PEF was calculated. Results: The predicted normal values of PEF(L/min) were -2.45$\times$Age(year) +1.36 $\times$ Height(cm)+427 in men, and -0.96 $\times$ Age (year) + 2.01 $\times$ Height (cm) + 129 in women. FEFmax derived from the maximal expiratory flow volume curve was less than by 125 L/min in men and 118 L/min in women respectively compared to PEF. $FEV_1$(ml) predicted by PEF was 5.98 $\times$ PEF(L/min) + 303 in men, and 4.61 $\times$ PEF(L/min) + 291 in women respectively. Conclusion : The predicted normal value of PEF measured by the peak flow meter was calculated and it could be used as a standard value of PEF while taking care of patients with airway obstruction. $FEV_1$, the gold standard of ventilatory function, could be predicted by PEF to a certain extent.

• Proceedings of the Korean Society For Composite Materials Conference
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• 2005.04a
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• pp.21-24
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• 2005

Three dimensional circular braided Glass/Aramid hybrid fabric/epoxy resin composite was fabricated. FBG sensor was embedded along the braid yam in order to monitor the internal dimensional changes of the 3-D braid composite. The amount of cure and thermal shrinkage of epoxy resin was also determined using FBG sensor system. FBG sensors with different grating length were embedded and their response were compared. The thermo-optic coefficient of FBG sensor was measured by several preliminary experiments. The internal strain that measured by FBG sensor and electric strain gauge was compared during compressive test. The released residual strain of the fabricated tubular composite was estimated using cutting method. The internal strain of the composite was estimated using FBG sensor system, and the result was compared with the value from electric strain gauge. It was found that FBG sensor system is a very useful technique to investigate inside region of complicated structure.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2003.10b
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• pp.51-54
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• 2003

Internal defects such as chevron crack occasionally occur in the process of cold extrusion or cold drawing. It is known that the existence and property of inclusion greatly influences the generation of the internal crack. However, in the plastic working field, research about the effect of the inclusion on the fracture is not theoretically analyzed. This paper describes effects of the physical property of inclusion on the internal fracture generation in the process. Prediction of fracture was evaluated by critical damage value calculated by the equation of Cockcroft & Latham and its change by the inclusion physical property such as size and stiffness was investigated.

• Transactions of Materials Processing
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• v.8 no.6
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• pp.612-619
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• 1999

Internal and external defects of an inner pulley for automobile air conditioner are investigated in this study. Inner pulley is a part of compressor clutch assembly of automobile air conditioner. In cold forging of inner pulley, the design requirement are to keep the same height of the inner rib and outer one and to make uniform distribution of hardness in the forged product. At the end of the forging of inner pulley, the piping defect as an external defect begins to form at the back center of the billet. The internal crack as an internal defect also occur at the adiabatic shear band which usually has maximum ductile fracture value. It is important to predict when the internal and external defects occur during the deformation process, in order to minimize the amount of discard that is generated. The finite element simulations are applied to analyze the defects. The validity of the computational results are examined by experiments. These computational results are in good agreement with the experimental ones.

• Journal of Advanced Marine Engineering and Technology
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• v.22 no.4
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• pp.451-459
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• 1998

THe influence of internal acoustic exitation through a square prism on the turbulent wake flow characteristics was investigated. The intermediate wake region where is about ten times the respective length of the body was experimentally investigated using a conditional phase average technique. At first the static base pressures of square prism and the shedding frequencies have been measured at various internal acoustic exciation frequencies. The experiment were performed under the four cases of internal acoustic excitation frequencies 0Hz 30Hz($St_e$=0.09) 65Hz($St_e$=0.20) 120Hz($St_e$=0.38) And velocity vector fields were presented and discussed. The influence of acoustic exvitation frequencies on the structure of intermediate turbulent wake region is evident. As the internal acoustic frequency increased shedding frequency gradually increased and aerodynamic force decreased. Also it was found that the vortex shedding occurs dratically well and shedding frequency reached nearly the same value as the internal acoustic frequency. but above Strouhal number 0.3 the influence disappeared.

• Clinical Endoscopy
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• v.55 no.4
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• pp.518-519
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• 2022