• The Journal of Internal Korean Medicine
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• v.26 no.3
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• pp.596-604
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• 2005

Objectives : Geopungjeseub-tang(Gufengchushi-tang) has been used in oriental medicine for many centuries as a therapeutic agent for hemiplegia caused by deficiency of qi(氣虛) and damp phlegm(濕痰). This study was performed to evaluate effects of Geopungjeseub-tang extract(GJT) on hemodynamics[regional cerebral blood flow(rCBF), pial arterial diameter(PAD), mean arterial blood pressure(MABP), heart rate(HR)] in normal rats and in rats with cerebral ischemia by middle cerebral artery(MCA) occlusion. Also, effects of adrenergic ${\beta}-receptor$, cyclooxygenase on response to GJT were evaluated. Methods : Laser-doppler flowmetry(LDF) measured changes of rCBF, MABP and HR. Video microscope and width analyzer measured changes in PAD. Results : rCBF and PAD increased after treatment with GJT(10mg/kg, i.v.) during the period of cerebral reperfusion, and pretreatment with indomethacin raised rCBF and PAD increased after treatment with GJT during the same period as above. Pretreatment with propranolol decreased rCBF, but increased after GJT treatment, but raised PAD increased after GJT treatment during this period of reperfusion. Conclusion : CR caused diverse responses were observed in rCBF and PAD after treatment with GJT. ACF action is mediated by adrenergic ${\beta}-receptor$ and cyclooxygenase. Result suggest that GJT has an anti-ischemic effect through the improvement of cerebral hemodynamics and has theraputic potential for cerebral apoplexy.

• Herbal Formula Science
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• v.10 no.1
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• pp.93-103
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• 2002

This experimental studies were done to investigate the effects of Sambutang(SBT) and consitituent herbs on the regional cerebral blood flow(rCBF) and mean arterial blood pressure(BP) in rats. The results are as follows: SBT and consitituent herbs(SBT omitting Zingiberis Rhizoma Recens, Zingiberis Rhizoma Recens. Ginseng Radix and Aconiti iateralis preparata Radix) was increased rCBF significantly in a dose-dependent manner. SBT omitting Zingiberis Rhizoma Recens and Ginseng Radix were decreased significantly BP in rats. But, SBT, Aconiti iateralis preparata Radix and Zingiberis Rhizoma Recens were not affected BP in rats. According to the above findings. it is suggested that SBT causes a diverse response of rCBF, and specially the rCBF by increasing SBT is mediated action of Zingiberis Rhizoma Recens.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2005.11a
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• pp.201-206
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• 2005

The effect of internal liquid flow on spray plume characteristics was performed experimentally in subsonic crossflows. The injector internal flow was classified as three modes such as a normal, cavitation, and hydraulic flip. The objectives of the research are to investigate the effect of internal liquid flow on the spray plume characteristics and compare the trajectory of spray plume with previous works. The results suggest that the trajectory of spray plume can be correlated as a function of liquid/air momentum flux ratio(q), injector diameter and normalized distance from the injector exit(x/d). It's also found that the injector internal turbulence influences the spray plume characteristics significantly.

• The Journal of Internal Korean Medicine
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• v.16 no.1
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• pp.181-196
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• 1995

The present experiments were designed to investigate the effects of BangPoongSan on the cardiovascular system in the experimental Animals. And thus the change of blood pressure, auricular blood flow, artery contraction, death rate, platelet aggregation repression, plasma coagulation factor activity, plasma antithrombin activity, whole blood viscosity and plasma viscosity were studied. The result were summarized as the followings: 1. BangPoongSan dropped the blood pressure in the spontaneous hypertensive rat. 2. The drug increased the auricular blood flow in rabbit. 3. The drug relaxed the artery contraction by pretreated norepinephrine in white rat. 4. The drug inhibited the death rate of mouse which was led to thromboembolism by serotonin and collagen. 5. The drug inhibited the platelet aggregation in rat. 6. The drug prolonged the prothrombin time and activated partial thromboplastin time on the test of plasma coagulation factor activity in rat, but was not valuable. 7. The drug presented the antithrombin activity in rat. 8. The drug reduced the whole blood viscosity and plasma viscosity in rat, but the latter was not valuable. According to the results, Bangpoongsan increased the blood flow and dropped the blood pressure by dilatation of blood vessel smooth muscle. And the drug presented the antithrombin acivity, inhibited the platelet aggregation and reduced blood viscosity. Therefore these effects are assumed to improve the cardiovascular circulation disorder and prevent thrombosis.

• Journal of the Society of Naval Architects of Korea
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• v.48 no.6
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• pp.544-551
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• 2011

The internal flows of moonpool usually causes huge added resistance on drillships, and those are very complex to analyze. Therefore, not only experimental approaches but also numerical simulations are required for better investigations when dealing with the hydrodynamic problems of moonpool. In the present research, numerical simulations are used to find out why the resistance increases by moonpool on a running drillship. That is, the three-dimensional numerical simulations and model tests are carried out to examine the characteristics of internal flow and added resistance by changing the section of the moonpool in both longitudinal and transverse directions. Finally, based on the present studies, an optimized shape of the moonpool is suggested, which effectively reduces added resistance, and that is confirmed with three-dimensional numerical simulations and model tests.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.25 no.8
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• pp.450-456
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• 2013

The composite electric oven is one of the fixing utensil, various functions are required. Steam generating function, which is one of its functions, and allows various food cooking. The location of the outlet of the steam generator is designed around ease of installation, consideration of internal fluid is not. Distribution of the steam can not be non-uniformly. Accordingly, cooking time becomes longer, the energy consumption increases. As a result of the analysis, it was confirmed stagnation phenomenon of the internal flow through the interpretation of the calculations for the position of the outlet of the steam generator existing. Further, by computing the analysis of various locations of the outlet of the steam generator, we investigated the distribution and characteristics of the internal flow.

• The KSFM Journal of Fluid Machinery
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• v.17 no.5
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• pp.67-71
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• 2014

Recently, the cross flow turbine attracts more and more attention for its good performance over a large operating regime at off design point. This study adopts a very low head cross flow turbine that has barely been studied before, and investigates the effect of air layer on the performance of the cross flow turbine. As open duct is applied in this study and free surface model is used between the air layer and water, an engineering definition of efficiency, instead of traditional definition of efficiency, is used. As torque at the runner fluctuates up and down at a reasonable limit, statistical method is used. Pressure and water volume fraction contours are shown to present the characteristics of air-water flow. With constant air suction in the runner chamber, the water level gradually drops below the runner and efficiency of the turbine can be raised by 10 percent. All considered, the effect of air layer on the performance of turbine is considerable.

• International Journal of Fluid Machinery and Systems
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• v.3 no.2
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• pp.102-112
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• 2010

Artificial heart pumps have attracted the attention of researchers around the world as an alternative to the organ used in cardiac transplantation. Conventional centrifugal pumps are no longer considered suitable for long-term application because of the possibility of occurrence of blood leakage and thrombus formation around the shaft seal. To overcome this problem posed by the shaft seal in conventional centrifugal pumps, the magnetically suspended centrifugal pump has been developed; this is a sealless rotor pump, which can provide contact-free rotation of the impeller without leading to material wear. In Europe, clinical trials of this pump have been successfully performed, and these pumps are commercially available. One of the aims of our study is to numerically examine the internal flow and the effect of leakage flow through the gap between the impeller and the pump casing on the performance of the pump. The results show that the pressure head increases compared with the pump without a gap for all flow rates because of the leakage of the fluid through the gap. It was observed that the leakage flow rate in the pump is sufficiently large; further, no stagnant fluid or dead flow regions were observed in the pump. Therefore, the present pump can efficiently enhance the washout effect.

• The KSFM Journal of Fluid Machinery
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• v.15 no.2
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• pp.57-62
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• 2012

The constant air volume flow fan can maintain constant flow rate to the wide range of exit pressure. Therefore, the use of this fan is increasing recently for ventilation of high building. Brushless DC motor is adopted to this fan because that has advantages of compactness and performance. But this type of motor protrude from impeller hub side to fan inlet. The Impeller inlet flow is influenced by size of this obstacle called hub. In this paper, the influence of hub shape on the fan performance characteristics are experimentally and numerically analyzed. CFX 12.0 is used to perform the fan internal flow analysis and numerical results are compared with the experiments. Depending on hub shape, internal loss is generated and the performance and efficiency are reduced. The best performance is occurred around $h/b_1$ = 0.25. The results of this study will be contribute to initial design of constant air volume flow fan development.

• The Journal of Korean Medicine
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• v.31 no.4
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• pp.178-186
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• 2010

Objectives: This study was to investigate the effect of moxibustion on peripheral blood flow by Doppler ultrasound in post-stroke hemiplegia patients. Methods: Moxibustion was applied on the points of LI4, TE3, TE5 and LI11 on the affected side, and blood flow of the radial artery was measured using the Minimax-Doppler-K device. Blood flow velocity and pulsation index were analyzed before, during, and after moxibustion. Results: The mean value of blood flow velocity in 13 patients showed a tendency of increase during moxibustion, but there was no significant difference in blood flow velocity before and after moxibustion, or pulsation index during and after moxibustion. In addition, among the five patients who showed marked increase tendency on the blood velocity graph, there was significant increase in blood velocity during, and after moxibustion compared with before moxibustion. Conclusions: This study suggests that moxibustion has an effect on peripheral blood flow in stroke patients with hemiplegia. Further validity tests with a larger scale sample are needed for the evidence of its practical use.