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Comparison between domestic and foreign Clinical guidelines and previous researches on Korean medicine for psoriasis to develop the clinical trial guideline of psoriasis using Korean medicine (건선 한약제제 임상시험 가이드라인 개발을 위한 관련 국내외 가이드라인과 기존 건선치료 한약제제 연구와의 비교)

  • Kang, Se Hyun;Moon, Young-Kyun;Jeong, Woo-Yeol;Nam, Hae-Jung;Kim, Yoon-Bum;Lee, Jun-Hee;Kim, Kyuseok
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.29 no.2
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    • pp.12-32
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    • 2016
  • Objectives : The objective of this study is to develop the strategies of the psoriasis clinical trials guideline on Korean medicine by comparison between Clinical guidelines and domestic and foreign clinical trials papers of psoriasis on Korean medicine. Methods : This study is based on analysis of papers on Clinical trials guidelines, Clinical practice guideline and clinical trials about Korean medicine. The papers were searched from Pubmed, Medline, Oasis(Oriental Medicine Advanced Searching Integrated System), Korean Traditional Knowledge Portal and Google portal database. Results : A total 8 Clinical practice guidelines and 2 Clinical trials guidelines were found. Moreover, there were 15 foreign papers about clinical trials and 29 internal articles about case studies. They suggested the diagnostic strategy, classification, effective outcome measure, severity measure, precaution of combination therapy, precaution and treatment period of clinical trials, safety evaluation, patterns of Korean Medicine, clinical specific features on psoriasis.Conclusions : The criteria of every item to provide the clinical trials guideline using Korean medicine on psoriasis were developed by apply the results. If we accumulate the more clinical articles on Korean medicine, it will be great help to develop the reliable standard of that guideline.

The Development of the Simple SHGC Calculation Method in Case of a Exterior Venetian Blind Using the Simulation (시뮬레이션을 이용한 외부 베네시안 블라인드의 약식 SHGC 계산법 개발)

  • Eom, Jae-Yong;Lee, Chung-Kook;Jang, Weol-Sang;Choi, Won-Ki
    • Journal of the Korean Solar Energy Society
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    • v.35 no.2
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    • pp.73-83
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    • 2015
  • When it comes to these buildings for business use, cooling load during summertime was reported to have great importance which, as a result, impressively increased interest in Solar Heat Gain Coefficient (SHGC). Such SHGC is considered to be lowered with the help of colors and functions of glass itself, internal shading devices, insulation films and others but basically, these external shading devices for initial blocking that would not allow solar heat to come in from outside the buildings are determined to be most effective. Of many different external shading devices, this thesis conducted an analysis on Exterior Venetian Blind. As for vertical shading devices, previous researches already calculated SHGC conveniently using concepts of sky-opening ratios. However in terms of the Venetian Blind, such correlation is not possibly applied. In light of that, in order to extract a valid correlation, this study first introduced a concept called shape factor, which would use the breadth and a space of a shade, before carrying out the analysis. As a consequence, the concept helped this study to find a very similar correlation. Results of the analysis are summarized as follows. (1) Regarding SHGC depending on the surface reflectance of a shade, an average of 2% error is observed and yet, the figure can always be ignored when it comes to a simple calculation. (2) As for SHGC of each bearing, this study noticed deviations of 4% or less and in the end, it is confirmed that extraction can be achieved with no more than one correlation formula. (3) When only the shape factor and nothing else is used for finding a correlation formula, the formula with a deviation of approximately 5% or less is what one would expect. (4) Since the study observed slight differences in bearings depending on ranges of the shape factors, it needed to extract a weighted value of each bearing, and learned that the smaller the shape factor, the wider the range of a weighted value. The study now suggests that a follow-up research to extract a simple calculation formula by dealing with all these various inclined angles of shade, solar radiation conditions of each region (the ratio of diffuse radiation to direct radiation and others) as well as seasonal features should be carried out.

A Study on Analysis of efficient Shelter Guide For Multiple-use Facilities (다중이용시설물에서의 효율적인 피난유도에 관한 현황 분석)

  • Park, In-Sook;Kim, Whoi-Yul;Kim, Byeoung-Su;Ahn, Byung-Ju;Lee, Yoon-Sun;Kim, Jae-Jun
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • 2007.11a
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    • pp.791-796
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    • 2007
  • As large-scale buildings, skyscrapers, and multi-purpose buildings recently increase in numbers dramatically, the internal space of such buildings becomes more and more large and complicated accordingly. Since such structures usually accommodate a number of random people, the potential possibilities of disastrous tragedies are high, and the rates of injury and physical damage caused by the complicated system of the building also increase as well. However, most of the shelter designs of the existing buildings are based on the specifications according to the assigned laws and involved regulations. In this case, only general criteria are referred to regardless of the characteristics of each structure while other disaster-related features are not taken into consideration sufficiently. Since any actual fire may cause a terrible calamity, in such plans, shelter inducement can be neither safe nor effective. Thus, this study examines and analyzes currently run disaster prevention systems and shelter inducement facilities with COEX Mall as its subject, and analyzes the responding system to each situation based on the fire scenarios by means of As-Is Model. Through this analysis, presented are the measures to solve the problems of current disaster prevention systems and to improve shelter inducement methods effectively.

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Intelligent Diagnosis Assistant System of Capsule Endoscopy Video Through Analysis of Video Frames (영상 프레임 분석을 통한 대용량 캡슐내시경 영상의 지능형 판독보조 시스템)

  • Lee, H.G.;Choi, H.K.;Lee, D.H.;Lee, S.C.
    • Journal of Intelligence and Information Systems
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    • v.15 no.2
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    • pp.33-48
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    • 2009
  • Capsule endoscopy is one of the most remarkable inventions in last ten years. Causing less pain for patients, diagnosis for entire digestive system has been considered as a most convenience method over a normal endoscope. However, it is known that the diagnosis process typically requires very long inspection time for clinical experts because of considerably many duplicate images of same areas in human digestive system due to uncontrollable movement of a capsule endoscope. In this paper, we propose a method for clinical diagnosticians to get highly valuable information from capsule-endoscopy video. Our software system consists of three global maps, such as movement map, characteristic map, and brightness map, in temporal domain for entire sequence of the input video. The movement map can be used for effectively removing duplicated adjacent images. The characteristic and brightness maps provide frame content analyses that can be quickly used for segmenting regions or locating some features(such as blood) in the stream. Our experiments show the results of four patients having different health conditions. The result maps clearly capture the movements and characteristics from the image frames. Our method may help the diagnosticians quickly search the locations of lesion, bleeding, or some other interesting areas.

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Study of the standardization of mobile laboratories by comparative analysis (이동식 측정분석차량 비교분석을 통한 표준화 방안 연구)

  • Ahn, Sung-Ryoung;Kim, Sungbum;Cho, Munsik;Chun, Kwangsoo;Kwon, Yongho;Seok, Gwangseol
    • Journal of the Society of Disaster Information
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    • v.9 no.3
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    • pp.282-289
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    • 2013
  • Mobile laboratory in the country (BL3 class) for research and technological development there has been continuous attempts . However, primarily as a feasibility problem and apply production techniques to move outside the laboratory by introducing the entire vehicle or domestic supply parts manufactured outside the shelter to the body in a way that introduces two special vehicles have been produced . Shelter in car parts production technology of positive pressure and negative pressure to secure perspective, and specific features of each facility through the analysis to find out the localization and standardization strategy direction and enhancements Check the current issue of the existing equipment was introduced and the internal structure of special vehicles the comparison function production technology at home and abroad through the analysis confirm and secure by applying advanced technology equipment and positive pressure inside the shelter facility that can be applied to the localization of the structure plan seeks to move existing analytical laboratory, equipped with the specifications of equipment Also introduced in the present state of the domestic vehicle production as portable measurement and analysis is to look for.

Saprolegnia parasitica Isolated from Rainbow Trout in Korea: Characterization, Anti-Saprolegnia Activity and Host Pathogen Interaction in Zebrafish Disease Model

  • Shin, Sangyeop;Kulatunga, D.C.M.;Dananjaya, S.H.S.;Nikapitiya, Chamilani;Lee, Jehee;De Zoysa, Mahanama
    • Mycobiology
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    • v.45 no.4
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    • pp.297-311
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    • 2017
  • Saprolegniasis is one of the most devastating oomycete diseases in freshwater fish which is caused by species in the genus Saprolegnia including Saprolegnia parasitica. In this study, we isolated the strain of S. parasitica from diseased rainbow trout in Korea. Morphological and molecular based identification confirmed that isolated oomycete belongs to the member of S. parasitica, supported by its typical features including cotton-like mycelium, zoospores and phylogenetic analysis with internal transcribed spacer region. Pathogenicity of isolated S. parasitica was developed in embryo, juvenile, and adult zebrafish as a disease model. Host-pathogen interaction in adult zebrafish was investigated at transcriptional level. Upon infection with S. parasitica, pathogen/antigen recognition and signaling (TLR2, TLR4b, TLR5b, NOD1, and major histocompatibility complex class I), pro/anti-inflammatory cytokines (interleukin $[IL]-1{\beta}$, tumor necrosis factor ${\alpha}$, IL-6, IL-8, interferon ${\gamma}$, IL-12, and IL-10), matrix metalloproteinase (MMP9 and MMP13), cell surface molecules ($CD8^+$ and $CD4^+$) and antioxidant enzymes (superoxide dismutase, catalase) related genes were differentially modulated at 3- and 12-hr post infection. As an anti-Saprolegnia agent, plant based lawsone was applied to investigate on the susceptibility of S. parasitica showing the minimum inhibitory concentration and percentage inhibition of radial growth as $200{\mu}g/mL$ and 31.8%, respectively. Moreover, natural lawsone changed the membrane permeability of S. parasitica mycelium and caused irreversible damage and disintegration to the cellular membranes of S. parasitica. Transcriptional responses of the genes of S. parasitica mycelium exposed to lawsone were altered, indicating that lawsone could be a potential anti-S. parasitica agent for controlling S. parasitica infection.

Housing Welfare Policies in Scandinavia: A Comparative Perspective on a Transition Era

  • Jensen, Lotte
    • Land and Housing Review
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    • v.4 no.2
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    • pp.133-144
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    • 2013
  • It is commonplace to refer to the Nordic countries of Sweden, Norway, Denmark, Finland and Iceland as a distinctive and homogenous welfare regime. As far as social housing is concerned, however, the institutional heritage of the respective countries significantly frames the ways in which social housing is understood, regulated and subsidized, and, in turn, how housing regimes respond to the general challenges to the national welfare states. The paper presents a historical institutionalist approach to understanding the diversity of regime responses in the modern era characterized by increasing marketization, welfare criticism and internationalization. The aim is to provide outside readers a theoretically guided empirical insight into Scandinavian social housing policy. The paper first lines up the core of the inbuilt argument of historical institutionalism in housing policy. Secondly, it briefly introduces the distinctive ideal typical features of the five housing regimes, which reveals the first internal distinction between the universal policies of Sweden and Denmark selective policies of Iceland and Finland. The Norwegian case constitutes a transitional model from general to selective during the past quarter of a decade. The third section then concentrates on the differences between Denmark, Sweden and Norway in which social housing is, our was originally, embedded in a universal welfare policy targeting the general level of housing quality for the entire population. Differences stand out, however, between finance, ownership, regulation and governance. The historical institutional argument is, that these differences frame the way in which actors operating on the respective policy arenas can and do respond to challenges. Here, in this section we lose Norway, which de facto has come to operate in a residual manner, due to contemporary effects of the long historical heritage of home ownership. The fourth section then discusses the recent challenges of welfare criticism, internationalization and marketization to the universal models in Denmark and Sweden. Here, it is argued that the institutional differences between the Swedish model of municipal ownership and the Danish model of independent cooperative social housing associations provides different sources of resistance to the prospective dismantlement of social housing as we know it. The fifth section presents the recent Danish reform of the governance model of social housing policy in which the housing associations are conceived of as 'dialogue partners' in the local housing policy, expected to create solutions to, rather than produce problems in social housing areas. The reform testifies to the strategic ability of the Danish social housing associations to employ their historically grounded institutional relative independence of the public system.

A Study on the Factors Affecting the Use and Satisfaction of Internet Ticketing Systems (인터넷 티켓팅 시스템의 사용과 만족에 영향을 미치는 요인)

  • Woo, Sung-Hwa;Kim, Kyung-Kyu;Chang, Hang-Bae;Shin, Ho-Kyoung
    • Asia pacific journal of information systems
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    • v.17 no.3
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    • pp.1-24
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    • 2007
  • With the development of information technology (IT), various information systems (IS) such as Web-based systems and mobile systems have appeared utilizing different technologies. However, recent studies on IS use and user satisfaction rarely account for technological differences among IS and environmental characteristics where IS are intended to be used. The purpose of this research is to investigate the determinants of the use of Web-based ticketing systems for cultural activities and to empirically validate their relationships. Environmental psychology suggests that human beings respond to external stimuli from environments with their emotions, and their emotional states influence human actions, e.g., IS use in this research. Applying environmental psychology to the use of Web-based systems in the culture and entertainment industry, we propose that web site characteristics first influence a user's internal state of mind (i.e., flow) and then the flow state influences the IS use. Studies related to the state of flow collectively affirm the key role played by the flow construct in shaping individual attitudes and behaviors toward IS. Users' flow states are captured by their shopping enjoyment, perceived behavioral control, and the level of concentration on the IS use. Referring to social presence theory, we have included such web site characteristics as content quality, context of web site, and community quality. In our research model, a second order construct is utilized to represent web site quality, because flow theory suggests that holistic experiences with web-based systems (rather than individual characteristics of the web site) are important in explaining the IS use. Further, we have included trust as another important factor influencing the IS use since business transactions on the web encompass higher uncertainty comparing to offline transactions. In order to test our hypotheses, we have conducted an online survey which results in 1,141 valid responses in the final sample. The data were collected from respondents who have experiences in Internet ticketing systems. Although it was a convenient sample, the sample represents a wide variety of user demographics. Validity and reliability of the research instrument were tested and research hypotheses were examined using PLS Graph 3.0. The results indicate that web site characteristics significantly influence the level of user concentration, user's enjoyment in shopping, and perceived behavioral control. Further, the use of Internet ticketing systems is influenced by users' flow states and trust in the web channel. User satisfaction is turned out to be affected by the use of Internet ticketing systems. Unlike extant research on the relationship between web site characteristics and its use, our study has found that, in the culture and entertainment industry, the impact of web site characteristics on IS use is mediated by a user's flow state. This finding has a practical implication that web site design should include as many features that enhance shopping enjoyment and concentration. Other practical implications of these findings and future research implications are also discussed.

Functional Dyspepsia (기능성 소화불량증)

  • Song, Kyung Ho
    • Korean Journal of Psychosomatic Medicine
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    • v.24 no.1
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    • pp.3-8
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    • 2016
  • Functional dyspepsia is one of the most common bowel disorders as prevalent of 7.7% Korean population. The cardinal manifestations include bothersome postprandial fullness, early satiation, epigastric burning or pain. These features are chronic and should be presented recurrently with no other compatible organic disease to explain the symptoms. Even though it is not life-shortening, functional dyspepsia usually make the health-related quality of life worse especially if other functional bowel disorder coexist. The coexistence of functional bowel disorders is called as 'overlap syndrome'. Anxiety, somatization and insomnia is more prevalent in overlap syndrome compared with sole functional bowel disorder. Therefore, it is worthwhile that physician interviews and elucidates whether the dyspeptic patient had other kinds of functional bowel disorders, and manages the underlying psychotic pathology. Placebo effect is large in functional dyspepsia, and there is only four kinds of prokinetics that is proven to be superior to placebo. Adverse events relating prolonged administration of prokinetics sometimes fatal or irreversible, physician willing to describe prokinetics should be familiar to the possible adverse effects and the relating risk factors. Pathologic acid reflux is not uncommon in functional dyspepsia, and acid-suppressant is equivalent to the prokientics in most of dyspeptic patients.

Forensic Analysis of HEIF Files on Android and Apple Devices (스마트폰에서 촬영된 HEIF 파일 특징 분석에 관한 연구)

  • Kwon, Youngjin;Bang, Sumin;Han, Jaehyeok;Lee, Sangjin
    • KIPS Transactions on Software and Data Engineering
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    • v.10 no.10
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    • pp.421-428
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    • 2021
  • The High Efficiency Image File Format (HEIF) is an MPEG-developed image format that utilizes the video codec H.265 to store still screens in a single image format. The iPhone has been using HEIF since 2017, and Android devices such as the Galaxy S10 have also supported the format since 2019. The format can provide images with good compression rates, but it has a complex internal structure and lacks significant compatibility between devices and software, making it not popular to replace commonly used JPEG (or JPG) files. However, despite the fact that many devices are already using HEIF, digital forensics research regarding it is lacking. This means that we can be exposed to the risk of missing potential evidence due to insufficient understanding of the information contained inside the file during digital forensics investigations. Therefore, in this paper, we analyze the HEIF formatted photo file taken on the iPhone and the motion photo file taken on the Galaxy to find out the information and features contained inside the file. We also investigate whether or not the software we tested support HEIF and present the requirement of forensic tools to analyze HEIF.