• 제목/요약/키워드: internal evaluation

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Evaluation of Pyunkang-tang® Administration on Hematological, Biochemical, and Protein and Lipid Profiles in Dogs

  • Park, Won-Keun;Park, Sung-Jae;Kim, Seung-Gon;Kang, Min-Hee;Park, Hee-Myung
    • 한국임상수의학회지
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    • 제33권5호
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    • pp.255-260
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    • 2016
  • $Pyunkang-tang^{(R)}$ is a kind of herbal medicine and has been used for the treatment of atopy and allergic disease in humans over forty years. The purpose of this study was to evaluate the hematological, biochemical, and protein and lipid electrophoresis profiles after the oral administration of $Pyunkang-tang^{(R)}$ in healthy dogs. Fifteen clinically healthy beagle dogs were selected and orally administered either 33 ml of $Pyunkang-tang^{(R)}$ (group I, n = 5), 16.5 ml of $Pyunkang-tang^{(R)}$ (group II, n = 5), or 33 ml of distilled water (group III, n = 5) 3 times a day for 4 weeks. The results of the hematological, serum biochemical, and urine analysis did not differ significantly among the 3 groups. The oral administration of $Pyunkang-tang^{(R)}$ for 4 weeks was associated with significant changes in the serum globulin levels and an elevation in the high-density lipoprotein (HDL) concentrations in groups I and II (p < 0.05), compared to group III. The ${\alpha}1-globulin$ and ${\gamma}-globulin$ levels were significantly increased in group I, and the ${\alpha}1-globulin$ and ${\beta}-globulin$ levels were significantly increased in group II. The ${\alpha}2-globulin$ levels were significantly decreased in both groups. During the short-term evaluation of $Pyunkang-tang^{(R)}$ administration, we did not detect any specific adverse effects in the dogs. However, further evaluation of the safety and efficacy of $Pyunkang-tang^{(R)}$ for the treatment of atopic disease in dogs is needed.

유동 덮개 형상이 축소 APR+ 내부 유동분포에 미치는 영향에 대한 수치해석 (Numerical Analysis for the Effect of Flow Skirt Geometry on the Flow Distribution in the Scaledown APR+)

  • 이공희;방영석;우승웅;김도형;강민구
    • 설비공학논문집
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    • 제25권5호
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    • pp.269-278
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    • 2013
  • In this study, in order to examine the applicability of computational fluid dynamics with the porous model to the analysis of APR+ (Advanced Power Reactor Plus) internal flow, simulation was conducted with the commercial multi-purpose computational fluid dynamics software, ANSYS CFX V.14. In addition, among the various reactor internals, the effect of flow skirt geometry on reactor internal flow was investigated. It was concluded that the porous model for some reactor internal structures could adequately predict the hydraulic characteristics inside the reactor in a qualitative manner. If sufficient computation resource is available, the predicted core inlet flow distribution is expected to be more accurate, by considering the real geometry of the internal structures, especially located in the upstream of the core inlet. Finally, depending on the shape of the flow skirt, the flow distribution was somewhat different locally. The standard deviation of the mass flow rate (${\sigma}$) for the original shape of flow skirt was smaller, than that for the modified shape of flow skirt. This means that the original shape of the flow skirt may give a more uniform distribution of mass flow rate at the core inlet plane, which may be more desirable for the core cooling.

공감과 사회적 평가가 아동의 친사회적 행동에 미치는 영향 (The Effect of Empathy and Social Evaluation on Children's Prosocial Behaviors)

  • 양성은;정문자
    • 아동학회지
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    • 제16권2호
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    • pp.97-112
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    • 1995
  • The purpose of this study was to investigate the effect of selected internal and situational factors on children's prosocial behaviors. While child's sex and trait empathy were chosen as internal factors, state empathy and social evaluation were regarded as situational factors. The subjects were 72 bays and 72 girls chosen from 288 eleven-year-olds. This selection was based on their emplathic scores measured by the Bryant Empathy Scale (1982). Half of the 144 children belonged to the high-trait empathic group and the other half to the low-trait empathic group. Within each of the high-and the low-trait empathic groups, equal numbers of boys and girls were randomly assigned to one of the two state empathy conditions and two social evaluation conditions. The state empathy conditions were divided into the arousal condition and the disregarding condition. To control social evaluation, subjects were led to believe that the experimenter either would or would not evaluate their donation of colorful ball-point pens to handicapped children. The data was analyzed by 4-way ANOVA [sex(2)${\times}$trait empathy(2)${\times}$state empathy(2)${\times}$social evaluation(2)]. The results were that (1) children's prosocial behaviors were significantly different by sex, state empathy, and social evaluation, and (2) children's prosocial behaviors were not significantly different by their trait empathy level.

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2009년 발생한 신종인플루엔자 대유행에 대한 정책적 대응 평가 (The Evaluation of Policies on 2009 Influenza Pandemic in Korea)

  • 최원석;김우주;정희진
    • Journal of Preventive Medicine and Public Health
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    • 제43권2호
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    • pp.105-108
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    • 2010
  • Objectives: To evaluate the policies on 2009 influenza pandemic in Korea at the end of first wave. Methods: The main policies and the estimation of these were described according to the progress of 2009 influenza pandemic. Results: The public health measures for containment were estimated to be successful in the early stage. The preparedness of antiviral agents and vaccines before the pandemic, risk-communication on pandemic influenza and policies of government including vaccines, and the education of health care worker and support of health care institutions was not enough to respond to the pandemic. Conclusions: The additional evaluation should be performed at the end of the pandemic in various aspects including health and socioeconomic effects.

Drug-induced blood cell dyscrasia associated with phenobarbital administration in a dog

  • Jung, Han-Byeol;Kang, Min-Hee;Park, Hee-Myung
    • 대한수의학회지
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    • 제55권4호
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    • pp.263-266
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    • 2015
  • A 13-year-old, spayed, female Chihuahua dog was referred for evaluation of fever, lethargy, and dyspnea. Hematologic evaluation revealed severe neutropenia, thrombocytopenia, and mild anemia. The dog had been undergoing phenobarbital therapy for the past 7 weeks because of generalized seizures due to meningoencephalomyelitis of unknown etiology. After ruling out other possible causes of cytopenias, a tentative diagnosis was made of drug-induced blood cell dyscrasia. The neutropenia and thrombocytopenia resolved after discontinuation of phenobarbital (8 days and 15 days after discontinuation, respectively). This is the first case report in Korea to demonstrate blood dyscrasia associated with idiosyncratic adverse effects of phenobarbital.

역문제 해석을 통한 탄성체 내부의 잔류응력 평가 (Evaluation of internal residual stresses in an elastic body by solving inverse problem)

  • 이상훈;김현규
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2008년도 추계학술대회A
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    • pp.597-602
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    • 2008
  • Most of structural analyses are concerned with the deformation and stress in a body subjected to external loads. In many fields, however, the interpretation of inverse problems is needed to determine surface tractions or internal stresses. In this study, the inverse processes by using the finite elements and the boundary elements are formulated for the evaluation of internal residual stresses from displacements measured on a remote surface. Small errors in the measured displacements often result in a substantial loss of accuracy of an inverse system. We use the Tikhonov regularization techniques to regularize the ill-conditioned system. Advantages and disadvantages are discussed through numerical examples.

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고리형 내부 보강재를 가진 X형 관이음부의 축방향 강도 평가 (Axial Strength Evaluation for Tubular X-Joints with Internal Ring Stiffener)

  • 조현만;류연선;김정태
    • 한국전산구조공학회:학술대회논문집
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    • 한국전산구조공학회 2001년도 봄 학술발표회 논문집
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    • pp.162-169
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    • 2001
  • Tubular joints are usually reinforced using thicker can section or ring stiffeners to increase the load carrying capacity. In this paper, a numerical study has been performed for evaluation of axial strength for X-joints with internal ring stiffener, The finite element analysis software was used for nonlinear strength analysis. According to variation of ring geometries, the effect of ring stiffener for X-joints are investigated. Internal ring stiffener is found to be efficient improving ultimate strength of tubular joints. Relations of thickness of ring and axial strength are observed considering geometric parameters of ring stiffeners.

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항공기 엔진 구성품 내부 구조 설계에 대한 구조 안전성 평가 (Evaluation of Structural Integrity about Structural Design for Internal Components of Aircraft Engine)

  • 박현범
    • 항공우주시스템공학회지
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    • 제17권5호
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    • pp.58-62
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    • 2023
  • 본 연구에서 항공기 엔진 내부 구성품의 구조 설계 결과에 대한 구조 안전성 평가 연구를 수행하였다. 엔진 내부 구성품에 라디에이터와 인터쿨러가 장착된다. 따라서 비행중에 라디에이터와 인터쿨러의 안전성을 검토하였다. 구조 해석을 통해 구조 안전성을 평가하였다. 구조 해석 기법은 유한 요소 해석 기법을 활용하였다. 구조 설계 및 해석을 위하여 가속도 하중을 고려하였다. 구조 안전성 평가 결과 구조 설계 결과는 타당한 것으로 확인되었다.

의류제품 구매과정에 있어서 내적준거가격의 영향 (Assessing the Impact of Internal Reference Price on Clothing Purchase Process)

  • 이규혜;이은영
    • 복식
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    • 제54권6호
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    • pp.1-12
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    • 2004
  • Price is one of the most important components of marketing mix. For consumers, price is an always-existing cue and definite evaluation criteria. However, information on price is meaningful only when it is perceived. Sources of price perception can be the actual retail price at the selling point, the internal reference price expected by consumers for a certain clothing product, and the external reference price advertised by marketer such as the price before mark-down. The purpose of this study was to investigate the influence of internal reference price on consumers' purchasing process of clothing products. A questionnaire including clothing stimuli was developed in order to assess consumers' internal reference price level. Usable data from 680 adult female urban residents were used for data analysis. Results indicated that consumers with relatively lower internal reference price tend to react low-price focused external reference price and use discount stores and unit price promotions. Consumers with relatively higher internal reference price advertisement are likely to have higher level of education, tend to infer price information to higher quality or prestige of products, and purchase clothing with regular retail price or coupons.