• Journal of the Korean Chemical Society
• /
• v.38 no.12
• /
• pp.921-923
• /
• 1994

• Proceedings of the Zoological Society Korea Conference
• /
• 1998.10b
• /
• pp.167.2-167
• /
• 1998

No Abstract, See Full Text

• Proceedings of the Materials Research Society of Korea Conference
• /
• 2007.11a
• /
• pp.107.1-107.1
• /
• 2007

• 한국생물공학회:학술대회논문집
• /
• 2005.10a
• /
• pp.270-271
• /
• 2005

• Bulletin of the Korean Chemical Society
• /
• v.25 no.5
• /
• pp.747-750
• /
• 2004

• YAKHAK HOEJI
• /
• v.45 no.4
• /
• pp.321-327
• /
• 2001

The synthesis of novel taxol analogues with an amine moiety at the 7- and 10-positions to examine the BBB penetration was described. The analogues were synthesized from 2'-O-(tert-butyldim-ethylsilyl)taxol and 2'-0-(tert-butyldimethylsilyl) -7-O-(triethylsilyl)-10-deacetyltaxol, the key intermediates, in 2 steps via the esterification with heterocyclic amino acids and the subsequent desilylation reaction.

• Archives of Pharmacal Research
• /
• v.27 no.10
• /
• pp.985-989
• /
• 2004

A functional divergency oriented synthetic approach to the azoninone (9-membered lactams), key intermediate for the indolizidine alkaloids library, using amide enolate induced aza-Claisen rearrangement has been achieved.

• KSBB Journal
• /
• v.15 no.5
• /
• pp.415-422
• /
• 2000

Enzymatic resolution is becoming increasingly important in the production of optically active pharmaceutical drugs and is now challenging the traditional synthetic methods for production of a variety of chiral intermediates and products. This article reviews the recent advances in chirotechnology using enzymes as a catalyst to resolve chiral compounds. The review focuses on the recent trends in chirotechnology and the application of enzymes to the production of industrially valuable pharmaceutical drugs.

• Proceedings of the Zoological Society Korea Conference
• /
• 1999.10b
• /
• pp.300.2-300
• /
• 1999

No Abstract, See Full Text

• Bulletin of the Korean Chemical Society
• /
• v.12 no.6
• /
• pp.716-717
• /
• 1991