• Development and Reproduction
• /
• v.21 no.1
• /
• pp.1-10
• /
• 2017

The use of human mesenchymal stem cells (hMSCs) in cell-based therapy has attracted extensive interest in the field of regenerative medicine, and it shows applications to numerous incurable diseases. hMSCs show several superior properties for therapeutic use compared to other types of stem cells. Different cell types are discussed in terms of their advantages and disadvantages, with focus on the characteristics of hMSCs. hMSCs can proliferate readily and produce differentiated cells that can substitute for the targeted affected tissue. To maximize the therapeutic effects of hMSCs, a substantial number of these cells are essential, requiring extensive ex vivo cell expansion. However, hMSCs have a limited lifespan in an in vitro culture condition. The senescence of hMSCs is a double-edged sword from the viewpoint of clinical applications. Although their limited cell proliferation potency protects them from malignant transformation after transplantation, senescence can alter various cell functions including proliferation, differentiation, and migration, that are essential for their therapeutic efficacy. Numerous trials to overcome the limited lifespan of mesenchymal stem cells are discussed.

• Journal of the Society of Disaster Information
• /
• v.5 no.2
• /
• pp.88-106
• /
• 2009

The potential risks of Korean public security has been increasing by economic stagnation. As a result of this, a feeling of unrest about our society causes expansion of private security industry as well as necessity of professional education. It has been 15years to produce security expert in colleges which is professional education institute, and academic efforts and contributions to society are shown remarkable results for the period. A private security industry had got public interest as a potential favorable job, because of increasing dependence of public to take care of unrest facts. Many colleges have introduced courses about public security because of facing necessity of professional education system. Then total 59 institutes including 22 universities and 37 colleges introduce courses of public security. Although name of courses are diverse depends on institution, purpose of course or members of course, the ultimate purpose of these courses is preventing public from crimes and managing public security. A fixed and out of date education system of universities in Korea can not produce talent person who people, companies and government want. The institutions have been recruiting many student so far, and it shows growth of the industry in quantity aspects. However quality aspect of the industry has been failed because it is hard to get a job for graduated students. Consequently, to improve quality of the industry people need cooperation of institution, professors and students.

• Journal of Korea Society of Digital Industry and Information Management
• /
• v.11 no.1
• /
• pp.121-133
• /
• 2015

IoT utilized network vitalization between objects are being rapidly established within current IT communication environment. Therefore the worth of smart mirrors is rising for it is a tool to allow online network between objects to be possible in human communication environment. For effective IoT generation's communication, this research intends to evaluate the smart mirror's value for practical uses based on the users' experiences. For the UX evaluation according to the locations where it will be used, Peter Morville's Honeycomb model and Jocob Nielsen's usage evaluation principles were referred to analyze effectiveness of 4 factors, utilization convenience, communication effectiveness, mass interest and space adequateness on households, public places and work places. Hence, we have were led to an objective result through statistical analysis method based on survey. As a result, we have confirmed the smart mirror's positive influence on the users' effective communication in all places. Especially in households, utilization convenience and space adequateness appeared to be high that confirmed sufficient users' need for the home-automation services. In public places, the communication effectiveness and space adequateness ranked high to confirm that the smart mirror utilization is adequate to provide location information. Also, in work places, the mass adequateness was high that we were able to confirm that supply of work place-specific service contents would bring meaningful results to the users. The smart mirrors are the adequate method to provide effective communication in IoT generation with high possibilities in further development.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.14 no.3
• /
• pp.1337-1362
• /
• 2020

Advances in localization-based technologies and the increase in ubiquitous computing have led to a growing interest in location-based applications and services. High accuracy of the position of a wireless device is still a crucial requirement to be satisfied. Firstly, the rapid development of wireless communication technologies has affected the location accuracy of radio monitoring systems employed locally and globally. Secondly, the location is determined using standard complex computing methods and needs a relatively long execution time. In this paper, two geolocalization techniques, based on trigonometric and CORDIC computing processes, are proposed and implemented for Bluetooth-based indoor monitoring applications. Theoretical analysis and simulation results are investigated in terms of accuracy, scalability, and responsiveness. They show that the proposed techniques can locate a target wireless device accurately and are well suited for timing estimation.

• Journal of the Korea Furniture Society
• /
• v.23 no.3
• /
• pp.290-297
• /
• 2012

Recently, interest in wooden construction have been growing by increasing needs and demands for eco-friendly and traditional wooden building(Hanok). Especially, Hanok has the technical development in manufacturing the mortise-tenon joint without fasteners(precut), so it could be called to modernization, industrialization and popularization. But the structural design and analysis of the structure were not regulated and had the difficulty to consider the variation of wooden member and to conduct the difficulty in the structural analysis and the design of the joint. In this study, the stiffness ratio of wooden mortise and tenon joint was evaluated according to the vertical loading, lintel and loading speed. The joint was distinguished in semi-rigid joint regardless of their factors. The stiffness ratio was 0.40 in vertical loading, 0.50 without vertical loading and 0.44 in horizontal loading with high speed. This study would be utilized to the structural analysis and design with structural analysis and design program.

• The Plant Pathology Journal
• /
• v.24 no.3
• /
• pp.245-268
• /
• 2008

The outcome of plant-pathogen interactions is influenced significantly by endogenous small molecules that coordinate plant defence responses. There is currently tremendous scientific and commercial interest in identifying chemicals whose exogenous application activates plant defences and affords protection from pathogen infection. In this review, we provide a survey of compounds known to induce disease resistance in plants, with particular emphasis on how each compound was originally identified, its putative or demonstrated mechanism of defence induction, and the known biological target(s) of each chemical. Larger polymeric structures and peptides/proteins are also discussed in this context. The quest for novel defence-inducing molecules would be aided by the capability for high-throughput analysis of candidate compounds, and we describe some issues associated with the development of these types of screens. Subsequent characterization of hits can be a formidable challenge, especially in terms of identifying chemical targets in plant cells. A variety of powerful molecular tools are available for this characterization, not only to provide insight into methods of plant defence activation, but also to probe fundamental biological processes. Furthermore, these investigations can reveal molecules with significant commercial potential as crop protectants, although a number of factors must be considered for this potential to be realized. By highlighting recent progress in the application of chemical biology techniques for the modulation of plant-pathogen interactions, we provide some perspective on the exciting opportunities for future progress in this field of research.

• Journal of the Korean Society for Precision Engineering
• /
• v.30 no.8
• /
• pp.870-877
• /
• 2013

There has been much recent research interest in developing numerous kinds of human-machine interface. This field currently requires more accurate and reliable sensing systems to detect the intended human motion. Most conventional human-machine interface use electromyography (EMG) sensors to detect the intended motion. However, EMG sensors have a number of disadvantages and, as a consequence, the human-machine interface is difficult to use. This study describes a muscle volume sensor (MVS) that has been developed to measure variation in the outline of a muscle, for use as a human-machine interface. We developed an algorithm to calibrate the system, and the feasibility of using MVS for detecting muscular activity was demonstrated experimentally. We evaluated the performance of the MVS via isotonic contraction using the KIN-COM$^{(R)}$ equipment at torques of 5, 10, and 15 Nm.

• Journal of the Korean Society for Precision Engineering
• /
• v.30 no.4
• /
• pp.359-367
• /
• 2013

With recent growth of the economy and development of construction technology, the increase of high-rise buildings is appearing rapidly in urban areas. For this reason, the interest in building maintenance has also been increasing. However, it has many safety problems because it is difficult for the workers to access the exterior wall of building. Therefore, the maintenance system of high-rise building stands out as being important issues to be developed, so that a variety of robot systems have been developed to accomplish the building-wall maintenance works. In this paper, the maintenance robots are classified in painting, inspecting, cleaning systems according to the maintenance works. Then, their locomotion and adhesion mechanisms are analyzed including their applicability to the real maintenance works. This study can be used to develop maintenance robotic system that is more efficient and stable than existing ones.

• Journal of Korean Society of Rural Planning
• /
• v.18 no.1
• /
• pp.47-57
• /
• 2012

The following study has examined possible methodological approach and prospect of implementing storytelling in rural tourism field. It is aimed towards deducing principles of space composition behind securing placeness of rural tourism village through storytelling. The research had been conducted by archival research and case study on field of interest, and its findings are as follows: 1) Storytelling exhibits principles of narrative structure (exposition, complication, climax, and resolution) in various fields, and has shown tendency to structuralize a plot. 2) It can be said that storytelling is deeply related with people's associations of their inner mind. This can be a logical explanation of a certain sight or location, which is a physical environment itself being the actual narrator and distributor in storytelling. 3) In order to convey a story in a more convincing way, storytelling a naming strategy based on a rhetorical technique, which has been shown to positively influence creating unique placeness of a rural village. As indicated in our study, means of storytelling-"Continuity and tourist circulation of space composition with a narrative structure, spatial hierarchical order, concealment and revelation, cast, and naming based on rhetorical technique and facilities positioning"-is a viable solution that can bring recovery of the rural village's unique placeness, as well as spatial development for sustainable rural tourism.

• Transactions of the Korean Society for Noise and Vibration Engineering
• /
• v.26 no.5
• /
• pp.501-510
• /
• 2016

Capabilities of several beamforming techniques are compared for estimating the position of a moving source. Beamforming has enabled to widen our perspective of aeroacoustics in wind tunnel experiments and has provided useful approach in array measurements. Meanwhile beamforming techniques have been developed in a way to improve estimation accuracy and to save ing effort at the same time. In order to achieve reasonable outcome from aeroacoustic measurement, it is important to identify the spectral characteristics of source and to select an appropriate beamformer. Though aeroacoustic sources normally generates broadband noises, many array signal processing have been focused on narrowband processing which makes calculation numerically efficient. However, calculation in frequency-domain requires selection of single frequency of interest which affects spatial resolution and sidelobe level as a consequence. To be able to localize broadband noise source, it is proposed to use broadband beamforming. The formulas implements the deletion of diagonal term from cross spectral matrix. In this study, trajectory of flying source emitting broadband noise was simulated and several beamformers are applied.